Clinical trials: Intraabdominal Infections
Intra Abdominal Infections, Appendicitis Acute
Diagnosis of Abdominal Pain Using RNA Levels: The NATURAL Study
The NATURAL Study is a prospective, observational, pragmatic study of RNA biomarkers of infections to aid in the diagnosis of abdominal pain.
- Conditions
- Intra Abdominal Infections, Appendicitis Acute, Pyelonephritis, Diverticulitis
- Trial name
- NATURAL (NCT07579312)
- Testing
- TruNAV, an RNA-based blood test for host immune activation by infections
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- True Bearing Diagnostics, Inc.
Acute Appendicitis
Presentation and Outcomes of Acute Appendicitis During COVID Pandemic
Acute appendicitis (AA) is a frequent cause of acute abdominal pain in emergency rooms around the world [1]. The lifetime risk of developing AA is estimated to be about 8% [1-3].
- Trial name
- AA (NCT05104346)
- Testing
- appendectomy
- Where
- Egypt
- Volunteers
- 1,945 people
- Sponsor
- Mansoura University
Appendicitis Acute
Leave or Laparoscopic Appendectomy With Normal Findings - a Regional Cohort Study
Based on a regional cohort, this study we will try to demonstrate the superiority of routine laparoscopic appendectomy vs. leaving an intraoperative assessed normal appendix in situ in cases of normal findings at diagnostic…
- Trial name
- NCT06000020
- Testing
- Laparoscopic appendectomy
- Where
- 4 sites in Denmark
- Volunteers
- 1,435 people
- Sponsor
- Nordsjaellands Hospital
Appendicitis
Open Versus Laparoscopic Appendectomy
The aim of this prospective randomized trial is to compare the feasibility of open with laparoscopic appendectomy in suspected acute appendicitis.
- Trial name
- NCT00908804
- Testing
- open appendectomy, laparoscopic appendectomy
- Where
- Finland
- Sponsor
- North Karelia Central Hospital
Appendicitis, Child
Conservative Treatment of Acute Appendicitis in Children
This is a feasibility study that will be performed at the Astrid Lindgren Children´s Hospital, Karolinska University Hospital, Stockholm, Sweden.
- Trial name
- CONSAPP Pilot (NCT01572558)
- Testing
- Appendectomy, Conservative, non-surgical treatment
- Where
- Sweden
- Volunteers
- 51 people
- Sponsor
- Karolinska University Hospital
Appendicitis
Diagnostic Performance of C Reactive Protein and Delta CRP in Acute Appendicitis
The diagnosis of acute appendicitis is difficult and despite important advances in medical sciences, detailed patient questioning and precise medical examination are the main keystones of the diagnosis of acute appendicitis and…
- Trial name
- dCRPappend (NCT02730585)
- Testing
- C-reactive protein measurement
- Where
- Tunisia
- Volunteers
- 500 people
- Sponsor
- University of Monastir
Acute Appendicitis
TACTILE : Validation of a Teleconsultation-Based Predictive Score for the Diagnosis of Acute Appendicitis in Children Using Artificial Intelligence Methods
Acute appendicitis is the most common abdominal surgical emergency in children and a frequent cause of pediatric emergency department visits.
- Trial name
- TACTILE (NCT07479849)
- Testing
- Score-based appendicitis risk classification in teleconsultation
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Angers
Peritonitis, Primary Closure
Outcome of Primary vs Delayed Primary Closure of Laparotomy in Dirty Abdominal Wounds
This randomized controlled trial is designed to evaluate and compare two different wound management strategies-primary closure (PC) and delayed primary closure (DPC)-in patients undergoing emergency laparotomy for peritonitis The…
- Conditions
- Peritonitis, Primary Closure, Delayed Primary Closure
- Trial name
- NCT07531576
- Testing
- Delayed Primary Laparotomy wound Closure, Primary Abdominal Closure
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Ayub Teaching Hospital
Chronic Renal Failure
Open Label Trial to Establish the Equivalence Between ANDY-Disc® and Ultrabag® in Patients on CAPD.
Apart from haemodialysis, continuous ambulatory peritoneal dialysis (CAPD) is another effective therapy for end stage renal disease (ESRD).
- Trial name
- NCT00255619
- Testing
- Baxter's UltraBag® and FMC Andy·Disc®
- Where
- 6 sites in Malaysia
- Volunteers
- 264 people
- Sponsor
- Ministry of Health, Malaysia
Tuberculosis; Abdomen
Acute Presentation and Management of Abdominal Tuberculosis: A Ten-year Experience at a Tertiary Care Center in Pakistan
A prospective interventional study was conducted in Services Instituton of Medical Sciences all patients who underwent emergency laparotomy from 2008-2018 due to abdominal tuberculosis. Data were analyzed using SPSS version 21
- Trial name
- NCT03918226
- Testing
- exploratory laparotomy
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Services Hospital, Lahore
Outcome
Treatment in Right Colon Diverticulitis Patients
The right colon diverticula, unlike those in the left colon, contain all layers of the colon and is called the true diverticulum. Perforation is observed less frequently due to its full thickness.
- Trial name
- NCT04746326
- Testing
- Failure conservative treatment, Surgery, Conservative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Tepecik Training and Research Hospital
Preoperative Anxiety, Children
Effects of Cartoons and Mobile Games on Preoperative Anxiety and Fear in Children With Appendicitis: An RCT
his study aims to evaluate the effects of cartoon viewing and mobile game playing on preoperative anxiety and fear levels in children aged 7-12 years who are hospitalized for appendicitis surgery.
- Conditions
- Preoperative Anxiety, Children, Appendicitis (Diagnosis), Fear
- Trial name
- NCT07640230
- Testing
- Cartoon-Assisted Distraction (Şüko Ameliyat Oluyor), Mobile Game
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Ankara City Hospital Bilkent
Intraabdominal Abscess, Wound Infection
Appendectomy in Children Performed by Residents in the Era of Laparoscopic Surgery
Introduction: An increasing proportion of childhood appendicitis is treated with laparoscopic appendectomy (LA). The investigators wanted to elucidate the outcome of childhood appendicitis treated primarily by residents in a…
- Trial name
- NCT01657565
- Where
- Denmark
- Volunteers
- 390 people
- Sponsor
- Odense University Hospital
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Appendiceal Abscess
Early Versus Delayed Operation for Perforated Appendicitis
The objective of this study is to scientifically evaluate two different operative strategies for perforated appendicitis with abscess.
- Trial name
- NCT00414375
- Testing
- Operation on Admission, Drainage and Interval Appendectomy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Mercy Hospital Kansas City
Abdominal Trauma, Abdominal Injury
A Non-Traumatic Binder for Temporary Abdominal Wall Closure
At the end of most abdominal operations, the fascial layer is closed by stitching edges of the wound together. However, because of logistic and/or technical reasons or the patient's critical condition, the surgeon is forced to…
- Conditions
- Abdominal Trauma, Abdominal Injury, Abdominal Infection, Abdominal Sepsis
- Trial name
- ABRO (NCT03815370)
- Testing
- Experimental: ABRO™ Binder Arm
- Where
- 4 sites in Canada
- Volunteers
- 140 people
- Sponsor
- Unity Health Toronto
Urinary Tract Infections, Pyelonephritis Acute
Safety, Tolerability, and Pharmacokinetics of Sulopenem in Adolescents
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of intravenous sulopenem and oral sulopenem etzadroxil/probenecid in adolescent patients.
- Conditions
- Urinary Tract Infections, Pyelonephritis Acute, Intraabdominal Infections
- Trial name
- NCT04700787
- Testing
- Sulopenem
- Where
- United States
- Sponsor
- Iterum Therapeutics, International Limited
Gram-negative Bacterial Infections
Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative Infections
The purpose of this study is to evaluate how Aztreonam (ATM) and Avibactam (AVI) are processed in pediatric participants. This study also aims to understand participant safety and effects in pediatric participants.
- Trial name
- NCT05639647
- Testing
- ATM-AVI, BAT
- Where
- 22 sites in United States, China and 6 more
- Volunteers
- 48 people
- Sponsor
- Pfizer
Acute Appendicitis
Single Incision Versus Conventional Laparoscopic Appendectomy
This is a randomized prospective study comparing single incision versus conventional laparoscopic appendectomy for management of acute appendicitis.
- Trial name
- NCT01424631
- Testing
- single incision laparoscopic appendectomy, conventional laparoscopic appendectomy
- Volunteers
- 2 people
- Sponsor
- Mansoura University
Appendicitis
Magnetic Resonance Imaging (MRI) of Appendicitis in Children
Study to find out if MRI can diagnose appendicitis in children as well as or better than CT scan and/or ultrasound scan performed at the same time. No additional contrast material or sedation will be used to perform the MRI.
- Trial name
- NCT00723788
- Testing
- MRI of the abdomen
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's National Research Institute