Clinical trials: Intraabdominal Infections
Gastric Ulcer With Perforation But Without Obstruction, Colon Cancer
Domestic Surgical Robot Clinical Study
Central South University in collaboration with Tianjin University developed the first domestically produced Chinese minimally invasive surgical (MIS) robot system which named "Micro Hand S" in 2013.
- Conditions
- Gastric Ulcer With Perforation But Without Obstruction, Colon Cancer, Cholecystolithiasis, Appendicitis
- Trial name
- NCT02752698
- Testing
- Micro Hand S robotic surgery, laparoscopic surgery, da Vinci robotic surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Acute Appendicitis
Comparative Study on the Diagnostic Validity of the Alvarado Score, Appendicitis Inflammatory Response (AIR), and Adult Appendicitis Score (AAS) in Acute Appendicitis at East Lancashire Hospitals NHS Trust (ELHT)
This retrospective observational study aims to compare the diagnostic accuracy of Alvarado Score, Appendicitis Inflammatory Response (AIR) Score, and Adult Appendicitis Score (AAS) in predicting histologically confirmed acute…
- Trial name
- DV-AAA ELHT (NCT07804238)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- East Lancashire Hospitals NHS Trust
Incisional Hernia, Peritonitis
Prophylactic Implantation of Biologic Mesh in Peritonitis
Patients undergoing emergency surgery for peritonitis are at increased risk of abdominal wall-related complications. In patients with peritonitis the risk of incisional hernia (IH) is extremely elevated.
- Trial name
- NCT04681326
- Testing
- biological prosthesis
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Appendicitis
Practical Advantages of Single-port Over Three-port Laparoscopic Appendectomy in Children
Despite growing popularity, practical advantages of single-port laparoscopic appendectomy (SLA) over conventional three-port laparoscopic appendectomy (CLA) have yet to be established well in pediatric population.
- Trial name
- PASTA (NCT03106467)
- Testing
- Single-port laparoscopic appendectomy, Three-port laparoscopic appendectomy
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Hallym University Medical Center
Acute Appendicitis
Efficacy of Transversus Abdominis Plane Block in Alleviating Acute Appendicitis
This study aims to evaluate the efficacy of Transversus Abdominis Plane (TAP) block in preoperative pain management for patients diagnosed with acute appendicitis who are scheduled for emergency surgery in the emergency…
- Trial name
- NCT06808737
- Testing
- Transversus Abdominis Plane Blockage
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Ankara City Hospital Bilkent
Appendicitis
Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in Children
Several prior studies have demonstrated that medical management of acute appendicitis in adults is a safe first-line therapy option.
- Trial name
- NCT02991937
- Testing
- Piperacillin/Tazobactam, Surgical Treatment
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Appendicitis
Abdominal Drainage During Appendicectomy - Resources Down the Drain: A Retrospective Cohort Study
The investigators performed a retrospective review of all patients undergoing appendicectomy from March-November 2018 using the online theatre database and discharge letters.
- Trial name
- NCT04163211
- Testing
- Abdominal drain
- Where
- United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The Whittington Hospital NHS Trust
Complicated Intra-abdominal Infection, Hosptial Acquired Pneumonia
A Study to Determine the Efficacy, Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) Versus Meropenem (MER) ± Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria.
A Phase 3 comparative study to determine the efficacy, safety and tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) versus Meropenem (MER) ± Colistin (COL) for the treatment of serious infections due to Gram…
- Conditions
- Complicated Intra-abdominal Infection, Hosptial Acquired Pneumonia, Ventilator Associated Pneumonia
- Trial name
- REVISIT (NCT03329092)
- Testing
- ATM-AVI, MTZ, MER
- Where
- 157 sites in United States, Argentina and 19 more
- Volunteers
- 422 people
- Sponsor
- Pfizer
Surgical Site Infection, Post-Op Infection
Analysis of Risk Factors for Surgical Site Infections in Patients With Acute Abdomen at Hospital of State University of Haiti
The purpose of this study is to identify the risk factors associated with surgical site infection.
- Trial name
- NCT06480344
- Where
- Haiti
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Haiti
Complicated Intra-abdominal Infections (cIAI)
A Study to Evaluate the Safety and Tolerability of Eravacycline in Pediatric Patients Aged 8 to 17 With Complicated Intra-abdominal Infections (cIAI)
A Phase 2 trial to assess safety, tolerability, and pharmacokinetics of eravacycline in pediatric patients aged 8 to <18 years with cIAI.
- Trial name
- NCT06794541
- Testing
- IV Eravacycline 2mg/kg, IV Eravacycline 1.5mg/kg
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- Tetraphase Pharmaceuticals, Inc
Complicated Intra-abdominal Infection
Safety and Efficacy Study to Compare IV CXA 101/Tazobactam and Metronidazole With Meropenem in Complicated Intraabdominal Infections
A Phase 2, multicenter, prospective, randomized, double-blind study of CXA-101/ tazobactam (1000/500 mg q8h) and metronidazole (500 mg q8h) IV infusion vs.
- Trial name
- NCT01147640
- Testing
- CXA-101/ tazobactam and metronidazole
- Where
- 33 sites in United States, Argentina and 3 more
- Volunteers
- 122 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Laparoscopic Appendectomy
Comparison Between Metallic Clip Ligation and Suture Ligation of Appendicular Stump in Laparoscopic Appendectomy
Laparoscopic appendectomy is the standard procedure for acute appendicitis. Among the various steps of the procedure one of the rate limiting step is the ligation of the appendicular stump which can be done using suture material…
- Trial name
- NCT07129746
- Testing
- Metallic clip ligation of the appendicular stump, Suture ligation of appendicular stump
- Where
- Pakistan
- Volunteers
- 10 people
- Sponsor
- Jinnah Hospital
Enhanced Recovery After Surgery, Appendicitis
Safety and Efficacy of ERAS Therapeutic Protocol for Complicated Appendicitis in Children
Complicated appendicitis in pediatrics is frequent, potentially serious and complex to manage. The implementation of a ERAS model would allow optimizing perioperative care, offering a shorter hospital stay, reducing complications…
- Conditions
- Enhanced Recovery After Surgery, Appendicitis, Children, Only
- Trial name
- ERAS (NCT05511194)
- Testing
- Enhanced Recovery After Surgery therapeutic protocol, Conventional management
- Volunteers
- 40 people
- Sponsor
- Instituto Mexicano del Seguro Social
Intra Abdominal Infections
Soluble Immune Checkpoints in Intra-Abdominal Infections
Intraabdominal infections is a life-threatening syndrome with a high incidence and a significant economic burden. The early-stage cytokine storm and the late-stage immunosuppression contribute to the mortality of sepsis.
- Trial name
- NCT07689266
- Testing
- Soluble Immune checkpoint levels
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Postoperative Complications, Appendicitis
Impact of SARS-Cov2 Pandemic on Severity of Perioperative Complications in Patients Undergoing Appendectomy
There are 2 types of surgical procedures to remove the appendix : open appendectomy or laparoscopic appendectomy. About 60000 appendectomies are performed every year in France.
- Conditions
- Postoperative Complications, Appendicitis, COVID-19 Pandemic, Appendicitis With Peritonitis
- Trial name
- SAP-19 (NCT05178251)
- Testing
- appendectomy
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Central Hospital, Nancy, France
Appendicitis
Impact of Oral Contrast in the Large Intestine on the Recognition of Appendix
Acute appendicitis is the most common cause of abdominal pain requiring surgical intervention. The gold standard test for the diagnosis of acute appendicitis is the CT scan.
- Trial name
- NCT02497183
- Testing
- ultrasound, iodine based solution of oral contrast material
- Where
- Israel
- Volunteers
- 1 people
- Sponsor
- HaEmek Medical Center, Israel
Chronic Peritoneal Dialysis
Method of Exit Site Care in Chronic Peritoneal Dialysis Patients
Peritoneal dialysis accounts for more than 70% of the dialysis modality in Hong Kong. Exit site infection (ESI) is one of the causes leading to peritoneal catheter removal. Appropriate exit-site care can prevent ESI.
- Trial name
- NCT00416338
- Testing
- film dressing by adhesive
- Where
- Hong Kong
- Volunteers
- 11 people
- Sponsor
- Chinese University of Hong Kong
Peritoneal Inflammation, Peritoneum; Injury
Effect of Warmed Humidified CO2 on Peritoneum During Laparotomy
The operating theatre is deliberately made to be cold and dry to prevent bacteria from growing. The problem with this is that during open abdominal surgery, the intestine and the overlying peritoneum is exposed to cold dry air.
- Trial name
- NCT02975947
- Testing
- Humidified, warmed CO2 insufflation of open peritoneum using Fisher & Paykel's HUMIGARD (Fisher & Paykel Healthcare Ltd, Auckland, New Zealand), Standard heating
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- Concord Repatriation General Hospital
Appendicitis Acute, Cesarean Wound Disruption With Postnatal Complication
Are Cesarean Section and Appendectomy in Pregnancy and Puerperium Interrelated?
It is not known whether appendectomy for acute appendicitis (AA) increases the Cesarean section (CS) rate and whether CS increases the likelihood of AA and appendectomy in the early puerperium.
- Trial name
- APPENDECTOMY (NCT04876547)
- Testing
- appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Amasya University
Complicated Intra-Abdominal Infections
Antibiotic Resistant Bacteria Among Patients With Severe Intraabdominal Infections
The objectives of the study were: 1. To study risk factors for colonization and infection with antibiotic resistant bacteria among patients with severe IAI before and after antibiotic treatment and surgical intervention. 2.
- Trial name
- Bakki (NCT00860587)
- Volunteers
- 200 people
- Sponsor
- University Hospital, Linkoeping