Clinical trials: Intubation; Complication
Tracheal Intubation
Flow Sensor and Colourimetric Capnometer in Verifying Tracheal Tube Positioning in Term and Preterm Infants
This is a multicentre clinical trial with medical device. As currently recommended by international neonatal resuscitation guidelines, the most reliable method to verify the correct positioning of the endotracheal tube, in…
- Trial name
- FlowNET (NCT05162313)
- Testing
- confirmation of endotracheal tube positioning
- Where
- Italy
- Volunteers
- 105 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Intubation Complication
Effect of Benzydamine Hydrochloride to Postoperative Sore Throat in Pediatric Patients
This study is designed to examine the effect of benzydamine hydrochloride to postoperative sore throat in pediatric patients. We will spray benzydmaine hydrochloride or normal saline at oral cavity and the tip of endotracheal…
- Trial name
- NCT03074968
- Testing
- Benzydamine Hydrochloride, Normal saline
- Where
- South Korea
- Volunteers
- 142 people
- Sponsor
- Seoul National University Hospital
Intubation Complication, Adverse Events
CRICKET: Critical Events in Anaesthetised Kids Undergoing Tracheal Intubation
The investigators' overall objective is to assess the incidence of critical events related to tracheal intubation at all international study sites.
- Trial name
- CRICKET (NCT05804188)
- Testing
- tracheal intubation
- Where
- 8 sites in United States, Australia and 3 more
- Volunteers
- 105,000 people
- Sponsor
- Thomas Riva
Respiratory Distress Syndrome, Newborn, Endotracheal Intubation
An Educational Intervention to Improve the Success of Intubation in Newborns Using a Video Laryngoscope by Reducing the Time the Procedure Takes.
This research focuses on one of the most common problems in newborn medicine: breathing difficulties. Breathing problems are the most common reason for admission to our neonatal unit at the National Maternity Hospital.
- Conditions
- Respiratory Distress Syndrome, Newborn, Endotracheal Intubation, Neonatal Intubation Performance, Prematurity
- Trial name
- NINJA (NCT06898801)
- Testing
- Just-in-time video training
- Where
- Ireland
- Volunteers
- 140 people
- Sponsor
- University College Dublin
Cleft Palate, Cleft Lip
Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring
Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population.
- Conditions
- Cleft Palate, Cleft Lip, Laryngospasm, Bronchospasm
- Trial name
- NCT07651904
- Testing
- Standard General Anesthesia per Institutional Protocol
- Volunteers
- 150 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Intubation, Intubation Complications
A Stepped Wedge Cluster Randomised Trial Of Video Versus Direct Laryngoscopy For Intubation Of Newborn Infants
Many newborn babies have difficulty breathing. When babies need a lot of help, a doctor will intubate them - i.e. put a tube into their windpipe (trachea) - so that they can be given support with a breathing machine.
- Conditions
- Intubation, Intubation Complications, Infant, Newborn, Infant Respiratory Distress Syndrome
- Trial name
- NEU-VODE (NCT06757543)
- Testing
- Video laryngoscopy, Direct laryngoscopy with standard laryngoscope
- Where
- 17 sites in Croatia, Czechia and 8 more
- Volunteers
- 840 people
- Sponsor
- University College Dublin
Hyaline Membrane Disease, Preterm Infant
Evaluation of the Neonatal Autonomic Stress During Intubations Under Propofol in a Population of Premature Infants Under 33 w'GA
Hyaline membrane disease is one of the leading causes of morbidity and mortality in premature newborns in industrialized countries.
- Trial name
- PROPOSURF (NCT03721640)
- Testing
- electrocardiogram
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Infant, Newborn, Infant, Low Birth Weight
Delivery Room CPAP in Extremely Low Birth Weight Infants
This pilot study was designed to determine the feasibility of randomizing extremely low birth weight (ELBW) infants <28 weeks' gestation who required resuscitation to one of two resuscitation methods, either: (a) 100% oxygen by…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- DR-CPAP (NCT01223274)
- Testing
- CPAP/PEEP, Standard management practices
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- NICHD Neonatal Research Network
Newborn Morbidity, Pain
Epidemiology of Painful Procedures in Neonates
Sick or premature neonates are exposed to frequent painful and stressful procedures during their stay in neonatal intensive care units.
- Conditions
- Newborn Morbidity, Pain, Procedures, Intratracheal Intubation
- Trial name
- EPIPPAIN (NCT01346813)
- Where
- 21 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Hôpital Armand Trousseau
Airway Complication of Anesthesia
Optimal Head and Neck Position for Videolaryngoscopy
The introduction of videolaryngoscopy constituted a revolution in airway management since it could provide better laryngeal exposure (indirect) in situations of difficult or impossible visualization by direct laryngoscopy.
- Trial name
- NCT03810937
- Testing
- head position
- Where
- Saudi Arabia
- Volunteers
- 170 people
- Sponsor
- King Fahad Specialist Hospital Dammam
Infant, Newborn, Infant, Small for Gestational Age
Hydrocortisone for BPD
The Hydrocortisone and Extubation study will test the safety and efficacy of a 10 day course of hydrocortisone for infants who are less than 30 weeks estimated gestational age and who are intubated at 14-28 days of life.
- Conditions
- Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight, Infant, Premature
- Trial name
- NCT01353313
- Testing
- Hydrocortisone
- Where
- 20 sites in United States
- Volunteers
- 800 people
- Sponsor
- NICHD Neonatal Research Network
Ventilation, Intubation Complication
Quality of Ventilation With Facial Versus Nasal Mask vs Nasal Mask Anesthesia in Children 3 to 12 Years Old
In this single-blind clinical trial study, 70children who are candidates for lower abdominal elective surgery under general anesthesia presented at Imam Hossein Hospital in Isfahan will be included in the study and will be…
- Conditions
- Ventilation, Intubation Complication, Intubation; Difficult or Failed
- Trial name
- NCT05018468
- Testing
- Ventilation
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Isfahan University of Medical Sciences
Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care
SEPREVEN: a Stepped-wedge Randomised Controlled Trial
Adverse events are frequent in Neonatal Intensive Care Units' (NICU) patients and account for a high morbidity and mortality. Possible severe adverse events are central line associated bloodstream infections (CLABSI), ventilator…
- Conditions
- Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care, Catheter-related Bloodstream Infection (CRBSI) Nos, Quality of Healthcare
- Trial name
- SEPREVEN (NCT02598609)
- Testing
- Education program for NICU caregivers
- Where
- 12 sites in France
- Volunteers
- 8,000 people
- Sponsor
- Dr Caeymaex Laurence
Anesthesia Intubation Complication
Prediction of Optimal Pediatric Endotracheal Tube Size "Aged Based Formula Versus Ultrasonography"
Background: Ultrasound (US) imaging technique has recently emerged as a novel, simple, portable, noninvasive tool helpful for airway assessment and management.
- Trial name
- NCT03676387
- Testing
- ultrasound guided
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Infant, Premature
Nasogastric Tube in Premature Babies - Pain and Treatment
Does sucrose or pacifier influence pain in premature babies when a nasogastric tube is inserted?
- Trial name
- NCT00218946
- Testing
- Sucrose, Pacifier, sterile water
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Anesthesia Intubation Complication, Mechanical Ventilation Complication
Endotracheal Tube Audible Leak Test
The endotracheal tube (ETT) leak test (LT), or audible leak test is a widely performed assessment to verify appropriate tube size in neonates, infants and children.
- Trial name
- NCT02461017
- Testing
- Assess for Audible Endotracheal Leak, Assess for Endotracheal Leak with direct visualization under rigid bronchoscope
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Mississippi Medical Center
Anesthesia Intubation Complication
Learning and Performance of Glidescope® Videolaryngoscope Intubation
Glidescope laryngoscope was introduced as a novel tool for difficult intubation. Its learning curve was prooved on manikin but not in adult patients.
- Trial name
- NCT01790646
- Testing
- intubation
- Where
- 3 sites in Italy
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Anesthesia Intubation Complication
Cuff Pressure in Patients: Manometer vs Invasive Pressure Monitoring Setup
This is a prospective study looking at ways to measure the cuff pressure of cuffed endotracheal tubes (ETTs). We will be comparing a hand-held manometer (MM) to the transducer of an invasive pressure monitoring setup (IPMS)…
- Trial name
- NCT01885793
- Testing
- Cuffed endotracheal tube
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Senthil G. Krishna
Respiratory Failure, Cardiac Arrest
'Single Hand Used inTubaTing Laryngoscope Evaluation' Study
This is a study to compare the new ShuttleScope with the standard Macintosh Laryngoscope
- Conditions
- Respiratory Failure, Cardiac Arrest, Difficult Intubation, Anesthesia Intubation Complication
- Trial name
- SHUTTLE (NCT04310384)
- Testing
- ShuttleScope, MacIntosh Laryngoscope
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Hemodynamic Response, Acute Appendicitis
Lidocaine VS Hemodynamic, Metabolic and Hormonal Response
Intravenous lidocaine - a potent local anesthetic with analgesic and anti- inflammatory properties has been shown to be an effective adjunct that reduces intra and postoperative opioid consumption and facilitates pain management…
- Conditions
- Hemodynamic Response, Acute Appendicitis, Complication of Treatment, Opioid Consumption
- Trial name
- NCT05238506
- Testing
- Intravenous lidocaine, Normal saline infusion
- Where
- Poland
- Volunteers
- 132 people
- Sponsor
- Medical University of Warsaw