Clinical trials: Intubation
Endotracheal Intubation
Videolaryngoscopy in the Critically Ill
Endotracheal Intubation (ETI) is done to place a plastic tube in a patient's trachea (windpipe) to assist with breathing. Patients admitted to the intensive care unit (ICU) are the sickest of patients and the majority of them…
- Trial name
- VICI (NCT00911755)
- Testing
- Endotracheal Intubation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Intubation, Intratracheal, Infant, Newborn
Video- Or Direct Laryngoscopy for Endotracheal Intubation in Newborns
Endotracheal intubation is a critical intervention for newborn babies. Laryngoscopy is the crucial part of endotracheal intubation.
- Conditions
- Intubation, Intratracheal, Infant, Newborn, Laryngoscopes
- Trial name
- VODE (NCT04994652)
- Testing
- Videolaryngoscopy, Direct laryngoscopy
- Where
- Ireland
- Volunteers
- 214 people
- Sponsor
- University College Dublin
Apnea, Anesthesia
Functional Residual Capacity Under Apnoeic Oxygenation with Different Flow Rates in Children
During induction of general anaesthesia physiological breathing stops and needs to be artificially established with facemask ventilation, and finally tracheal intubation or placement of a supraglottic airway.
- Conditions
- Apnea, Anesthesia, Intubation Complication, Children, Only
- Trial name
- FUTURE (NCT05672329)
- Testing
- 0.2 L/kg/min, FiO2 1.0 + continuous jaw thrust, 2 L/kg/min, FiO2 1.0 + continuous jaw thrust, 4 L/kg/min, FiO2 1.0 + continuous jaw thrust
- Where
- Switzerland
- Volunteers
- 108 people
- Sponsor
- Thomas Riva
Intubation; Difficult or Failed
Standard Versus Hyperangulated Video Laryngoscopy Blades for Intubation in Neonates and Small Infants
The goal of this prospective randomized cross over clinical trial is to compare the difference in the percentage of glottic opening (POGO) between two different video laryngoscopy blades, the hyperangulated Cobalt blade and the…
- Trial name
- NCT05843565
- Testing
- Non-standard blade (NSB), Standard blade (SB)
- Where
- Lebanon
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Anesthesia, Intubation
Effect Of Position On Laryngeal Visualisation With The C-Mac Videolaryngoscope
The aim of this study is to demonstrate the effect of C-Mac videolaryngoscopy with Miller Blade size 0 and 1 on the intubation conditions in children less than 2 years age with a roll inserted under the shoulders.
- Conditions
- Anesthesia, Intubation, Laryngoscopy
- Trial name
- NCT03709979
- Testing
- C-MAC videolaryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Inonu University
General Anesthesia
Ultrasonography vs Cole Formula to Predict Endotracheal Tube Diameter
This study aims to compare the accuracy of measurement between ultrasonography and Cole formula in predicting uncuffed endotracheal tube diameter.
- Trial name
- NCT02754531
- Testing
- USG, Cole Formula
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Respiratory Distress Syndrome, Newborn
LISA vs Endotracheal Surfactant in Preterm Neonates: A Lung Ultrasound Distribution Study
This prospective, non-randomized, unblinded pilot study evaluates and compares the intrapulmonary distribution of exogenous surfactant in preterm neonates when administered via Less Invasive Surfactant Administration (LISA)…
- Trial name
- LISA-Ven-LUS (NCT07514481)
- Testing
- surfactant administration by ETT, surfactant administration by thin catheter
- Where
- Qatar
- Volunteers
- 22 people
- Sponsor
- Hamad General Hospital
Intubation
Comparison of Different Stylet Angles for Orotracheal Intubation Using C-MAC® Video Laryngoscopes in Infants
The purpose of this study is to investigate whether the difference in stylet curvature affects the ease of tracheal intubation using C-MAC videolaryngoscope in infants under 1 year of age.
- Trial name
- NCT04745936
- Testing
- Style curve similar to natural curvature of endotracheal tube, Style curve similar to hockey stick shape
- Where
- South Korea
- Volunteers
- 114 people
- Sponsor
- Seoul National University Hospital
Intubation Complication, Intubation; Difficult or Failed
The DAnish VIdeo IntubaTION (DA-VITION) Study
This study aims to train an AI for video-directed endotracheal intubation (VITION) to recognise the anatomical structures of the upper airway during video-directed endotracheal intubations.
- Trial name
- DA-VITION (NCT05884645)
- Testing
- Video-directed endotracheal intubation
- Where
- 2 sites in Denmark
- Volunteers
- 10,000 people
- Sponsor
- Lise Aunsholt
Uncuffed Endotracheal Intubation
Ultrasound and Paediatric Endotracheal Tube Size
The aim of the present study was to evaluate the role of ultrasound in paediatric patients to compare the correct size of an uncuffed endotracheal tube (ETT) with the minimal transverse tracheal diameter (MTTD) measured by…
- Trial name
- NCT01535300
- Testing
- Ultrasonography of the trachea
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Heidelberg University
Respiratory Failure
The Use of the GlideScope Ranger in Pediatric Critical Care Transport
This study seeks to assess the role of the GlideScope Ranger video laryngoscope in facilitating successful neonatal/pediatric intubation by pediatric critical care transport teams.
- Trial name
- NCT01054183
- Testing
- GlideScope Ranger Intubation, Direct Laryngoscopy
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Akron Children's Hospital
Airway Management, Infant ALL
Defining the 'Sniffing Position" in Infants and Toddlers - A Pilot Study
The "sniffing position" is widely accepted as a favorable position for direct laryngoscopy (DL) in both pediatric and adult patients.
- Conditions
- Airway Management, Infant ALL, Children, Only, Endotracheal Intubation
- Trial name
- NCT04410289
- Testing
- Airway positioning per specified protocol followed by Direct Laryngoscopy and Endotracheal Intubation, Airway positioning per provider preference followed by Direct Laryngoscopy and Endotracheal Intubation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Tufts Medical Center
Cuff, Airway Edema
Determining Optimal Cuff Volume in Pediatric Patients
Background and Aim: Cuffed endotracheal tubes with appropriate size, good cuff design and cuff pressure monitoring in pediatric patients can be used safely without increasing airway morbidity.
- Conditions
- Cuff, Airway Edema, Children, Only, Tracheal Intubation Morbidity
- Trial name
- NCT04948359
- Testing
- Group I (The patients intubated with cuffed ETT of ID number 4.5), Group II (The patients intubated with cuffed ETT of ID number 5.0), Group III ( The patients intubated with cuffed ETT of ID number 5.5)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Work Related Stress
Workload in Anesthesiological Practice
The study evaluates differences in perceived and objective workload in anesthetists during intubation procedure with a direct (Mcintosh) or indirect (Glidescope) laryngoscope.
- Trial name
- NCT04050241
- Testing
- Glidescope intubation, Mcintosh intubation
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Intubation Complication
Diagnostic Accuracy of Core Stethoscope Auscultation vs. Point of Care Ultrasound in Placement of Endotracheal Tube
Misplacement of endotracheal tube (ETT) can have devastating complications for patients, some of which include respiratory failure, atelectasis, and pneumothorax.
- Trial name
- NCT04797520
- Testing
- Eko CORE Stethoscope, Point of care ultrasound
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Cuff Overinflation, Cuff Underinflation
Cuff Pressure Regulation Apparatus for Tracheal Intubation in Children
Despite the expert recommendation about rigorous monitoring of tracheal cuff pressure using a continuous or intermittent technique, cuff underinflation and overinflation are common increasing the risk of microinhalation and…
- Trial name
- CPRATIC-2 (NCT04413318)
- Testing
- Electronic device (VBM©), Pneumatic device (Nosten©)
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infant, Newborn, Infant, Low Birth Weight
Delivery Room CPAP in Extremely Low Birth Weight Infants
This pilot study was designed to determine the feasibility of randomizing extremely low birth weight (ELBW) infants <28 weeks' gestation who required resuscitation to one of two resuscitation methods, either: (a) 100% oxygen by…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- DR-CPAP (NCT01223274)
- Testing
- CPAP/PEEP, Standard management practices
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- NICHD Neonatal Research Network
Hemodynamic Response, Acute Appendicitis
Lidocaine VS Hemodynamic, Metabolic and Hormonal Response
Intravenous lidocaine - a potent local anesthetic with analgesic and anti- inflammatory properties has been shown to be an effective adjunct that reduces intra and postoperative opioid consumption and facilitates pain management…
- Conditions
- Hemodynamic Response, Acute Appendicitis, Complication of Treatment, Opioid Consumption
- Trial name
- NCT05238506
- Testing
- Intravenous lidocaine, Normal saline infusion
- Where
- Poland
- Volunteers
- 132 people
- Sponsor
- Medical University of Warsaw
Videolaryngoscopy, Intensive Care Unit Syndrome
Awake Tracheal Intubation in Critical Care Patients
Tracheal intubation in critical care is a high-risk procedure requiring significant expertise and airway strategy modifications, such as awake intubation with video laryngoscope or flexible endoscope intubation.
- Trial name
- Awake (NCT05802316)
- Testing
- tracheal intubation using videolaryngoscope with a hyperangulated blade or standard intubation videolaryngoscopy (VL) and direct laryngoscopy (DL)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Johannes Gutenberg University Mainz
Nasal Intubation, Dental Surgery
Does Altering Magill Forceps Affect Nasal Intubation Time
The purpose of this study is to see whether altering the angle of the Magill forceps by 45 degrees will affect nasal intubation time in pediatric dental surgery patients.
- Conditions
- Nasal Intubation, Dental Surgery, Pediatrics
- Trial name
- NCT02109211
- Testing
- Intubation with Magill forceps, Intubation with altered Magill forceps
- Where
- Canada
- Volunteers
- 133 people
- Sponsor
- University of Saskatchewan