Clinical trials: Iodine
Dental Caries
Effect of Silver Diamine Fluoride Application on Oral Microbiome of Healthy Pediatric Patient
This clinical trial aims to learn more about the working mechanism of an antimicrobial agent used to manage dental caries, especially in young, uncooperative children.
- Trial name
- NCT06699199
- Testing
- Silver diamine Fluoride 38%, Silver diamine fluoride- potassium iodide
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- King Abdulaziz University
Liver Cancer
Radioactive Iodine in Treating Patients Who Have Undergone Surgery for Liver Cancer
RATIONALE: Radioactive iodine may be effective in reducing the rate of recurrence of liver cancer after surgery to remove the tumor.
- Trial name
- NCT00027768
- Testing
- adjuvant therapy, iodine I 131 ethiodized oil
- Where
- 3 sites in Singapore
- Volunteers
- 300 people
- Sponsor
- National Medical Research Council (NMRC), Singapore
Tertiary Dentine, Indirect Pulp Capping
Silver Diamine Fluoride/ Potassium Iodide in Indirect Pulp Capping of Young Permanent Molars
The aim of this study is to evaluate and compare the clinical effectiveness of 38% silver diamine fluoride with and without potassium iodide with that of resin modified glass ionomer cement in indirect pulp capping of young…
- Trial name
- NCT04236830
- Testing
- Silver diamine fluoride/ potassium iodide, Silver diamine fluoride, Resin modified glass ionomer cement
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Nourhan M.Aly
Laceration Face, Wound Heal
Honey Versus Povidone-iodine on Laceration Wounds
This study evaluates healing time in usage of honey and povidone-iodine over paraffin gauze as dressings in the treatment of acute laceration wounds.
- Conditions
- Laceration Face, Wound Heal, Wounds and Injuries, Laceration Arm
- Trial name
- NCT03641053
- Testing
- Honey, Povidone-iodine, Paraffin gauze
- Where
- Indonesia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- S.K. Lerik General Hospital
Adenoviral Conjunctivitis
Treatment of Adenoviral Conjunctivitis With SHP640 Compared to Povidone-iodine (PVP-I) and Placebo
The purpose of this study is to determine if an investigational treatment is effective compared with placebo and PVP-Iodine in the treatment of adults and children with adenoviral conjunctivitis.
- Trial name
- NCT02998541
- Testing
- SHP640, PVP-I 0.6%
- Where
- 130 sites in United States, Australia and 14 more
- Volunteers
- 219 people
- Sponsor
- Shire
Excessive Iodine Status, Thyroid Dysfunction, Antepartum
Research on Excessive Iodine Status in Pregnancy
To explore main cause and health impact of iodine excess during pregnancy, we performed iodine evaluation for 390 consecutive pregnant women from January 1st, 2016 to December 31st, 2016.
- Conditions
- Excessive Iodine Status, Thyroid Dysfunction, Antepartum, Pregnancy Related, Neonatal Disorder
- Trial name
- NCT03422406
- Testing
- Dietary iodine intake restriction
- Volunteers
- 18 people
- Sponsor
- Peking Union Medical College Hospital
Neurocognitive Disorders
Evaluating the Long-term Neurocognitive Effects of Preconceptional Exposure to Iodinated Contrast on the Offspring
Iodinated contrast is commonly used in hysterosalpingography (HSG), a diagnostic tool in fertility work-up. This study aims to investigate the safety of contrast media used during HSG by evaluating the long-term effects on the…
- Trial name
- Neuro-H2Oil (NCT05168228)
- Testing
- Oil- versus waterbased contrast in hysterosalpingography (HSG)
- Where
- Netherlands
- Volunteers
- 64 people
- Sponsor
- Amsterdam UMC, location VUmc
Cognitive Performance
The Effect of Diet on Learning Abilities for Children in Kindergarden
The main aim of this intervention study is to test the effect of diet on improvement in cognitive performanc in kindergarden children aged 4-6 years.
- Trial name
- NCT02331667
- Testing
- Seafood, Non-seafood
- Where
- Norway
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- National Institute of Nutrition and Seafood Research, Norway
Fungal Keratitis
A Clinical Trial of the Treatment of Fungal Corneal Ulcers With Povidone-Iodine
The purpose of this study is to determine the effectiveness of 1.25% povidone-iodine ophthalmic solution for the treatment of small to medium sized fungal corneal ulcers compared with an antifungal antibiotic.
- Trial name
- NCT00516399
- Testing
- povidone-iodine 1.25% ophthalmic solution, natamycin ophthalmic suspension, USP 5%
- Volunteers
- 78 people
- Sponsor
- University of California, Los Angeles
Neuroblastoma
N2000-01: Double Infusion of Iodine I 131 Metaiodobenzylguanidine Followed by Autologous Stem Cell Transplantation
RATIONALE: Giving iodine I 131 metaiodobenzylguanidine (^131I-MIBG) may kill neuroblastoma cells by delivering radiation directly to the tumor.
- Trial name
- NCT00083135
- Testing
- filgrastim, autologous bone marrow transplantation, peripheral blood stem cell transplantation
- Where
- 7 sites in United States
- Volunteers
- 18 people
- Sponsor
- New Approaches to Neuroblastoma Therapy Consortium
Cognitive Function
Preconception Maternal Iodine Status and Offspring Cognitive Function:
Little is known about maternal iodine nutrition before conception and its relation with the child's cognitive function. Using samples and data from the Southampton Women's Survey, iodine measurements from urine collected before…
- Trial name
- NCT03322163
- Testing
- Exposure is maternal iodine
- Where
- United Kingdom
- Volunteers
- 12,583 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Iodine Deficiency, Goiter
The Effects of Iodized Salt on Cognitive Development in Ethiopia
Many school children in Ethiopia and their mothers are known to be iodine deficient. Prevalence in the Amhara region is around 29%.
- Conditions
- Iodine Deficiency, Goiter, Cretinism
- Trial name
- NCT01349634
- Testing
- Iodized salt
- Where
- Canada
- Volunteers
- 5,704 people, healthy volunteers welcome
- Sponsor
- McGill University
Urine Contamination
EPIC: Effect of Povidone Iodine Periurethral Cleansing on Level of Contamination With Clean Catch
The primary aim of this study is to see if the use of an antiseptic preparation (povidone iodine) versus cold normal saline, will decrease rates of urine contamination during the non-invasive Quick Wee (QW) collection of…
- Trial name
- NCT03933436
- Testing
- Iodine swabs., Saline flush.
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Travis Callahan
Radioactive Iodine-Induced Hypothyroidism in Graves Disease Patients
Factors Affecting Timing of Hypothyroidism Following Radioactive Iodine Therapy Patients With Graves Disease
The purpose of this retrospective study was to clarify the possible risk factors of early hypothyroidism after RAI therapy in Graves' disease.
- Trial name
- NCT05643365
- Testing
- Radioactive Iodine therapy
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Assiut University
COVID19
Virucidal Effect of Povidone Iodine on COVID-19 In-Vivo
It is an established fact that, corona virus spread through the respiratory droplets. Colonization of the virus in oropharynx and/or nasopharynx is considered to be major factor for transmissibility of the virus through…
- Trial name
- VEP-COV (NCT04549376)
- Testing
- Povidone-Iodine 0.4% NI, Povidone-Iodine 0.5% NI, Povidone-Iodine 0.6% NI
- Where
- Bangladesh
- Volunteers
- 200 people
- Sponsor
- DR. MALA KHAN
Iodine Deficiency
Prevalence of Iodine Deficiency in Remote Communities of Haiti
Haiti is one of the few remaining countries that is at risk of iodine deficiency disorders. In the 2018 survey, iodized salt was found in <20% of households and iodine excretion from non-pregnant and pregnant women suggested…
- Trial name
- NCT05275452
- Testing
- No intervention
- Where
- Haiti
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iodine Deficiency
Study of the Effect of Iodized Oil Supplementation During Infancy
In iodine-deficient countries or regions that have inadequate iodized salt distribution, the World Health Organization (WHO) recommends choosing one of two methods to improve iodine intakes in breastfeeding infants: 1) iodine…
- Trial name
- INSIGHT (NCT01126125)
- Testing
- Iodized oil
- Where
- Morocco
- Volunteers
- 241 people
- Sponsor
- Swiss Federal Institute of Technology
Iodine Excess in Pregnancy, Selenium Excess in Pregnancy
The Correlation Between Iodine and Selenium Status in Pregnancy and Risk of Thyroid Disease
Two hundred and ninety pregnant women with gestational age less than 20 weeks will be recruited in this study. Selenium and iodine conditions, and risk of thyroid disease will be monitored until termination of pregnancy, with…
- Conditions
- Iodine Excess in Pregnancy, Selenium Excess in Pregnancy, Iodine Deficiency in Pregnancy, Selenium Deficiency in Pregnancy
- Trial name
- NCT03761602
- Testing
- Not applicable (for observational studies)
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Rongrong Li
Thyroid Neoplasms
P53 in Differentiated Thyroid Cancer
In clinical practise patients with negative radioiodine scan with positive tyhroglobulin is considered as radioiodine resistant or in another words in the process of dedifferentiation.
- Trial name
- NCT01954134
- Where
- Turkey (Türkiye)
- Volunteers
- 199 people
- Sponsor
- Cumhuriyet University
Blood Culture Contamination
• Comparison of Blood Culture Contamination Rates
In this study, blood culture contamination rates will be compared in patients who used povidine/iodine-alcohol and chlorhexidine/alcohol, which were applied before the blood culture was taken by randomized two methods routinely…
- Trial name
- NCT05576233
- Testing
- disinfection of the surface that the blood culture is taken
- Volunteers
- 500 people
- Sponsor
- Dr. Behcet Uz Children's Hospital