Clinical trials: Iodine
Thyroid Dysfunction
Thyroid Dysfunction in Head and Neck Surgery Patients
Specific Aim I: Determine absorption of iodine after oropharyngeal application of povidone-iodine 10% solution when used in head and neck surgery involving the upper aero-digestive tract.
- Trial name
- NCT00592514
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Arkansas
Neoplasms, Prostate
Quality of Life After Permanent Interstitial Iodine Seed Prostate Brachytherapy
Retrospective study to analyze Quality of life in men after iodine seed brachytherapy for localized prostate cancer
- Trial name
- NCT02652000
- Testing
- No intervention in this retrospective study
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Kantonsspital Graubünden
Insular Thyroid Cancer, Recurrent Thyroid Cancer
Bortezomib in Treating Patients With Metastatic Thyroid Cancer That Did Not Respond to Radioactive Iodine Therapy
This phase II trial is studying how well bortezomib works in treating patients with metastatic thyroid cancer that did not respond to radioactive iodine therapy.
- Conditions
- Insular Thyroid Cancer, Recurrent Thyroid Cancer, Stage II Follicular Thyroid Cancer, Stage II Papillary Thyroid Cancer
- Trial name
- NCT00104871
- Testing
- Bortezomib
- Where
- 9 sites in United States
- Volunteers
- 24 people
- Sponsor
- National Cancer Institute (NCI)
Peripheral Arterial Disease, Renal Insufficiency
Ultra Low Iodine Loaded Spectral CT Angiography (CTA)
The objectives of this study are: Evaluation of ultra-low iodine load CTA protocols of the aorta and lower extremities. To investigate whether dual-layer in combination with with virtual monoenergetic imaging (VMI) allows for…
- Trial name
- NCT05488899
- Testing
- Half iodine Spectral CT, Standard iodine conventional CT
- Where
- Norway
- Volunteers
- 216 people
- Sponsor
- University Hospital, Akershus
Thyroid Cancer
Differentiated Thyroid Cancer Patients Treated With Different Doses of Radioactive Iodine.
1. Determine the frequency of utilizing single and multiple doses of radioactive iodine (RAI) in treatment of differentiated thyroid cancer. 2.
- Trial name
- NCT06134830
- Testing
- RAI
- Volunteers
- 100 people
- Sponsor
- Assiut University
Thyroid Cancer
177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer
Background: Oncocytic (Hurthle cell) thyroid cancer (HTC) is a rare disease with few treatment options. Researchers are developing a radioactive drug that targets a protein that appears in high numbers on HTC cancer cells.
- Trial name
- NCT06991738
- Testing
- 68Ga-DOTA-TATE PET Scan, Amino acid infusions, 177Lu-DOTA-EB-TATE
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Disinfectant Causing Toxic Effect
Chlorohexidine Versus Povidone Iodine as Apreoperative Ophthalmic Disinfectant
1. Is to assess the efficacy of preoperative disinfection with chlorohexidine and povidone iodine in different concentrations separately . 2. Is to compare the efficacy of chlorohexidine to povidone iodine. 3.
- Trial name
- NCT03957291
- Testing
- Chlorhexidine, Povidone-Iodine
- Volunteers
- 100 people
- Sponsor
- Assiut University
Dental Caries
Sequential PVP-I and FV
This prospective cohort study in children will determine if: topical povidone iodine 10% followed by topical fluoride varnish is superior to placebo iodine followed two different varnishes alone to prevent tooth decay (dental…
- Trial name
- NCT07683910
- Testing
- fluoride varnish, 2.5%, topical fluoride, 2.1%, Povidone Iodine Topical
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- Advantage Silver Dental Arrest, LLC
Skin Burns
The Counter-irritating Efficacy of Topical Povidone-iodine in Thermal Burns
Skin burns are one of the causes of disability, suffering and death in humans. Anecdotal, uncontrolled studies have shown the efficacy of povidone-iodine ointment in human skin burns, provided the preparation was applied shortly…
- Trial name
- NCT01350713
- Testing
- povidone iodine
- Where
- Israel
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Uveal Melanoma, Metastatic
Tebentafusp and Roginolisib in Uveal Melanoma to Prolong T-cell Homeostasis
This is a combination study of Tebentafusp and the PI3Kdelta inhibitor, Roginolisib
- Trial name
- TRIUMPH (NCT07203391)
- Testing
- roginolisib
- Where
- 2 sites in Australia
- Volunteers
- 8 people
- Sponsor
- St Vincent's Hospital, Sydney
Follicular Thyroid Cancer, SEER Database Analysis
Long-term Survival Outcomes of Total Thyroidectomy and Radioactive Iodine Therapy in Unilateral T3/T4 FTC
This study aims to thoroughly examine survival disparities in patients with T3 or T4 stage follicular thyroid carcinoma (FTC) as classified by the AJCC staging system.
- Trial name
- NCT06437873
- Testing
- Total Thyroidectomy (TT), Radioactive iodine treatment(RAIT)
- Volunteers
- 2,957 people, healthy volunteers welcome
- Sponsor
- Dezhou Hospital Qilu Hospital of Shandong University
Nocturia
Ancillary Nocturnal Urinary Symptoms Analyses for TRIUMPH
The TRIUMPH study is a randomized, double-blinded, 3-arm, parallel-group trial designed tocompare the effects of anticholinergic bladder therapy versus a) beta-3-adrenergic agonistbladder therapy and b) no bladder pharmacotherapy…
- Trial name
- NCT07829029
- Testing
- TolterodineTartrate ER, Mirabegron
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Esophageal Squamous Cell Carcinoma
High-concentration Small-volume Versus Low-concentration Large-volume Iodine Solution for Esophageal Chromoendoscopy
This clinical trial aims to test the participants' tolerance for different concentration iodine solutions during esophageal chromoendoscopy.
- Trial name
- NCT06063941
- Testing
- 1% Lugol's iodine solution, 5% Lugol's iodine solution
- Where
- 5 sites in China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Age-related Macular Degeneration, Diabetic Retinopathy
Povidone Iodine vs AVEnova: A Pre-injection Disinfection Study (PAVE Study)
To compare the efficacy and comfort of two FDA approved pre-injection antiseptics when used for intravitreal injections.
- Conditions
- Age-related Macular Degeneration, Diabetic Retinopathy, Diabetic Macular Edema
- Trial name
- PAVE (NCT04018482)
- Testing
- Povidone Iodine, Hypochlorous Acid
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- California Retina Consultants
Vaginal Delivery, Surgical Site Infection
Skip Prep of Vaginal Delivery to Prevent Puerperal / Perinatal Infection in Vaginal Delivery
This is a multi-center, randomized, controlled trial study to find whether use of chlorhexidine-alcohol or povidone-iodine for pre-vaginal delivery skin prep is superior to reduce postpartum infection in pregnant women with…
- Trial name
- NCT05122169
- Testing
- Povidone-Iodine, Chlorhexidine
- Volunteers
- 4,140 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Iron Deficiency (ID), General Anemia
Community Interventions to Improve Iron and Iodine Status in Mother and Child Dyads in Northern Ghana
BACKGROUND Ghana has reduced food insecurity prevalence by 49.2% in two decades. However, prevalence of malnutrition especially stunting (in <children5yr) has not matched the changes in food security levels.
- Conditions
- Iron Deficiency (ID), General Anemia, Iron Deficiency Anemia (IDA)
- Trial name
- NCT03754998
- Testing
- Intervention Group
- Where
- Ghana
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Michigan State University
ICU Patients Requiring a Central Venous Access
Chlorhexidine vs Povidone Iodine in Alcoholic Solutions for Prevention of Central Venous Catheter Infection
The best antiseptic solution for cateheter care remains unknown.High concentration in aquous solution or low concentration in alcoholic solution of chlorhexidine actbetter than povidone iodine in aquous solutions.
- Trial name
- NCT00259350
- Testing
- Skin disinfection
- Where
- France
- Volunteers
- 520 people
- Sponsor
- Poitiers University Hospital
Chronic Lymphocytic Leukemia
Safety and Efficacy Study of Iodine-131 Anti-B1 Antibody for Chronic Lymphocytic Leukemia
The purpose of this study is to test the safety of Iodine-131 Anti-B1 Antibody, to see what effects it has on patients with CLL and to determine the highest dose of Iodine-131 Anti-B1 Antibody that can be given without causing…
- Trial name
- NCT00022880
- Testing
- Iodine-131 Anti-B1 Antibody
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Corixa Corporation
Thyroid Function
Mothers and Babies at Yorkhill Thyroid Health Cohort
This is an observational study in pregnant mothers and their newborn babies. The rationale of the study is to examine early markers of the effects of iodine insufficiency during pregnancy on thyroid stimulating hormone (TSH) and…
- Trial name
- MABY (NCT02390128)
- Testing
- observational only
- Where
- United Kingdom
- Volunteers
- 697 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Chronic Rhinosinusitis (CRS)
Intra-Sinus Povidone-Iodine and Budesonide After Endoscopic Sinus Surgery for Chronic Rhinosinusitis
Endoscopic sinus surgery (ESS) is commonly performed in patients with chronic rhinosinusitis (CRS) to improve sinus drainage and allow better delivery of topical therapies after surgery.
- Trial name
- PVP-I (NCT07383402)
- Testing
- Povidone-Iodine and Budesonide Gel-Forming Suspension
- Volunteers
- 180 people
- Sponsor
- Amin Javer