Clinical trials: Irreversible Pulpitis
Pulpitis - Irreversible
Prognostic Biomarkers for Pulpotomy Outcome
This study will recruit 180 molars diagnosed with irreversible pulpitis. Full pulpotomy will be performed on 120 teeth, while RCT (root canal treatment) will be conducted on another cohort of 60 teeth as the control for assessing…
- Trial name
- NCT06514053
- Testing
- Full pulpotomy, Root canal treatment
- Where
- Hong Kong
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Irreversible Pulpitis
Comparing MTA Pulpotomy to Root Canal Treatment in Management of Permanent Molars With Irreversible Pulpitis in Children
Dental caries, highly prevalent amongst children, can cause pulpitis. Coronal pulpotomy provides an easier, cost-effective, conservative and biologically-driven treatment option compared to endodontic treatment in mature…
- Trial name
- NCT06488131
- Testing
- MTA Pulpotomy, Root Canal Treatment
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pulpitis - Irreversible
A-prf,Nanochitosan Combined With A-prf Compared to Chitosan for Symptomatic Irreversible Pulpitis of Mature Teeth
Clinical and radiographic assessment of A-prf,A-prf combined with nanochitosan compared to chitosan for symptomatic irreversible pulpits in lower permanent first molar
- Trial name
- NCT06438523
- Testing
- PULPOTOMY OF MATURE PERMENANT TEETH
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Irreversible Pulpitis
Post Operative Pain and Oral Health Related Quality of Life Following Pulpotomy VS Extraction of Permanent First Molar
The goal of this clinical trial is to compare between post operative pain and oral health related quality of life in participants receiving two treatments for first permanent mandibular molars with poor prognosis.
- Trial name
- NCT06420583
- Testing
- MTA pulpotomy, Extraction
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
Single Rotary File Pulpectomy in Primary Molars
The aim of this study is to compare the clinical effectiveness of a single rotary file system versus a multiple rotary files system in pulpectomy of primary molars
- Trial name
- NCT06146686
- Testing
- Fanta AF blue rotary files 20 taper 4, Fanta AF baby rotary files 20 , 25 , 30 taper 4
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis, Tooth Extraction
Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients
To evaluate the effectiveness of intra-osseous anesthesia using Quicksleepr5 in pain elimination during dental treatment in maxillary and mandibular primary molars, compared to conventional anesthesia.
- Trial name
- NCT06245161
- Testing
- Quicksleeper5, conventional anesthesia
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Root Canal Infection, Periapical Abscess
Comparing Different Single and Combination Chelating Agents on Sealer Penetration and Dentin Erosion.
The basic aim of root canal treatment is to reduce the microbial content and prevent further recontamination in the canal. Every tooth has a variable, complex canal anatomy consisting of ramifications, accessory and lateral…
- Conditions
- Root Canal Infection, Periapical Abscess, Irreversible Pulpitis, Apical Periodontitis
- Trial name
- NCT05778227
- Testing
- Ethylene Diamine Tetra Acetic acid, smearOFF, Etidronic acid /sodium hypochlorite
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Pulpitis - Irreversible
Assessing Success of MTA and Pre-mixed Bioceramic in Mature Teeth With Irreversible Pulpitis With Full Pulpotomy.
Although many pulpotomy agents are commercially available, there is a dearth of clinical research comparing the efficacy of these agents in treating individuals with irreversible pulpitis.
- Trial name
- GCP (NCT05853185)
- Testing
- Pro Root MTA®, EBRRM®
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Pulpitis - Irreversible
Full Pulpotomy Versus Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
Background The European Society of Endodontology (ESE) and the American Association of Endodontists (AAE) position statements on the management of deep caries and exposed pulp recommended adoption and promotion of strategies…
- Trial name
- NCT06002698
- Testing
- Root canal treatment (Control), Full pulpotomy (Experimental)
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
high-quality evidence is needed to add to current knowledge and also assess the long-term outcomes for full/complete pulpotomy after carious pulpal exposure in patients with signs and symptoms indicative of irreversible pulpitis
- Trial name
- NCT05726357
- Testing
- vital pulp therapy
- Where
- Egypt
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
This study is a randomised controlled trial for complete pulpotomy as an alternative to root canal treatment for teeth with clinical diagnosis of symptomatic irreversible pulpitis (i.e.
- Trial name
- NCT05964933
- Testing
- Complete Pulpotomy, Pulpectomy and Root Canal Treatment
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Pulpitis - Irreversible, Apical Periodontitis
Evaluation of Nano Bioactive Glass Combined With i-PRF Scaffold in Vital Pulp Treatments
With consideration of the previous studies regarding the properties of i-PRF, it will be used in combination with another bioactive material: (Nano-BAG) versus using of i-PRF only as a pulpotomy material with using a premixed…
- Trial name
- NCT05902936
- Testing
- Pulpotomy for mature permanent mandibular molars
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vital Pulp Treatment in Mature Permanent Teeth With Irreversible Pulpitis
Clinical and Radiographic Assessment of Nano-Bioactive Glass Combined With I-PRF Scaffold in Vital Pulp Treatments in Mandibular Molars With Closed Apices
Clinical, Radiographic and pain assessment of Vital pulp treatment in patients suffering from irreversible pulpitis in mature permanent molars.
- Trial name
- I-PRF (NCT05876520)
- Testing
- Total pulpotomy with I-prf mixed with Nano-bioactive glass
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis, Deep Caries
TheraCal LC Coronal Pulpotomy and MTA Coronal Pulpotomy in Mature Permanent Molars
To evaluate and compare the clinical and radiographic success rate of TheraCal LC and MTA for coronal pulpotomy of mature permanent molar in 9-14 year children.
- Trial name
- NCT05733468
- Testing
- Theracal LC, MTA
- Where
- India
- Volunteers
- 72 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Caries, Pulpitis - Irreversible
Outcome of Pulpotomy Versus Root Canal Therapy
Root canal therapy (RCT) is indicated once the pulp is diagnosed with irreversible pulpitis. Despite favorable success rate reported for RCT in vital cases, it is time consuming, and might increases fracture susceptibility of…
- Trial name
- NCT05279781
- Testing
- Non surgical root canal treatment, Pulpotomy
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Pulpitis - Irreversible
Efficacy of Combination of Biodentine and Simvastatin as a Pulp Capping Materials in Vital Pulpotomy of Primary Molars
Objective: This study was conducted to evaluate the efficacy of combination of biodentine with simvastatin as a pulpotomy agent for vital primary molars clinically and radiographically.
- Trial name
- NCT05582317
- Testing
- Biodentine, Simvastatin
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Pain, Symptomatic Irreversible Pulpitis
Ethyl Chloride Versus 5% Lidocaine for Topical Anesthesia of Oral Mucosa
Local anesthesia in the oral cavity is a pain full experience for the patient. All means should be made to reduce the pain and anxiety of the patient for needle stick procedures.
- Trial name
- NCT05306470
- Testing
- Ethyl chloride, 5% lidocaine gel
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Pulpitis - Irreversible, Tooth Decay
Efficacy of PRF and MTA as Compared to Calcium Hydroxide for Pulpotomy in Human Irreversibly Inflamed Permanent Teeth
Of all the various pulpotomy medicaments that have been studied till to date, three agents have been selected for this study to compare their efficacy.
- Trial name
- NCT05266859
- Testing
- Calcium hydroxide, MTA, PRF
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Liaquat College of Medicine and Dentistry
Cryotherapy Effect, Irreversible Pulpitis
Cryotherapy Efficacy During Pulp Therapy of the Mandibular First Permanent Molars in Children
The aim of the study is to assess the efficacy of cryotherapy application on the success of inferior alveolar nerve block (IANB) in reducing pain during pulp therapy of the mandibular first permanent molars with irreversible…
- Conditions
- Cryotherapy Effect, Irreversible Pulpitis, Pain
- Trial name
- NCT05441995
- Testing
- Cryotherapy
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Minia University
Carious Exposure of Pulp, Irreversible Pulpitis
Comparative Study of the Outcome of Partial and Full Pulpotomy in Irreversible Pulpits
This study aims at comparing the outcome of partial pulpotomy and full pulpotomy in the management of carious pulp exposures in permanent teeth with a clinical diagnosis of irreversible pulpits.
- Conditions
- Carious Exposure of Pulp, Irreversible Pulpitis, Pulpotomy
- Trial name
- NCT05279820
- Testing
- Partial pulpotomy, Full Pulpotomy
- Where
- Jordan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology