Clinical trials: Irreversible Pulpitis
Symptomatic Irreversible Pulpitis
Comparison of Postoperative Pain After Root Canal Irrigation in Symptomatic Irreversible Pulpitis
This randomized controlled trial will compare postoperative pain following root canal treatment in patients with symptomatic irreversible pulpitis.
- Trial name
- NCT07821359
- Testing
- Dexamethasone, Sodium Chloride 0.9%
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Pulpectomy, Pulpitis - Irreversible
Clinical and Radiographic Evaluation of E-IodoCal in Primary Molar Pulpectomy
This randomized controlled split-mouth clinical trial evaluates the clinical and radiographic performance of E-IodoCal paste compared to zinc oxide-eugenol (ZOE) as root canal filling materials in primary molar pulpectomies.
- Conditions
- Pulpectomy, Pulpitis - Irreversible, Zinc Oxide, Root Canal Obturation
- Trial name
- NCT07883200
- Testing
- E-IodoCal Root Canal Obturation (Group I), Zinc Oxide-Eugenol Root Canal Obturation (Group II)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Irreversible Pulpitis
Child's Behavior Using Single Rotary File System Versus Manual Instrumentation in Pulpectomy of Primary Molars
The primary aim is to compare the behavior of the children during using conventional manual instrumentation versus rotary instrumentation by single rotary system for pulpectomy in primary molars through a Randomized Clinical…
- Trial name
- NCT07415694
- Testing
- Fanta AF F one rotary files 20 taper 4, Manual files (k files ,Mani, Inc., Japan).
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis (SIP), Symptomatic Apical Periodontitis
Comparison of Postoperative Pain After Root Canal Treatment Using Hand-Held vs Rotary ProTaper Files: A Randomized Controlled Trial
This randomized controlled trial aims to compare postoperative pain after root canal treatment using two different types of ProTaper file systems: manual (hand-held) and rotary (engine-driven).
- Conditions
- Symptomatic Irreversible Pulpitis (SIP), Symptomatic Apical Periodontitis, Postoperative Pain After Endodontic Treatment
- Trial name
- NCT07887087
- Testing
- ProTaper Manual Root Canal Instrumentation, ProTaper Rotary Root Canal Instrumentation
- Volunteers
- 200 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Symptomatic Irreversible Pulpitis With Apical Peridontitis
Neurokinin A and Matrix Metalloproteinase 9 Levels in Gingival Crevicular Fluid Samples of Teeth With Symptomatic Irreversible Pulpitis With Symptomatic Apical Periodontitis
The aim of this study is to investigate the levels Neurokinin A and of Matrix Mtalloproteinase (MMP-9) in gingival crevicular fluid samples (GCF) as potential biomarkers for the diagnosis of symptomatic irreversible pulpitis with…
- Trial name
- NCT07289074
- Testing
- Gingival crevicular fluid samples from the symptomatic teeth and the healthy contrlateral teeth
- Where
- Egypt
- Volunteers
- 23 people
- Sponsor
- Hadeer Mostafa El Mohamady El Feky
Symptomatic Irreversible Pulpitis (SIP)
Short Term Comparative Assessment of MTA and Biodentine in Complete Pulpotomy for Symptomatic Irreversible Pulpitis
All Patients coming to the Operative Dentistry Department (DIDC-DUHS) with complain of pain in posterior teeth will be invited to participate. The treatment will be done by one dentist.
- Trial name
- NCT07483788
- Testing
- Biodentine pulpotomy
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Symptomatic Irreversible Pulpitis (SIP), Post Operative Pain After Root Canal Therapy
Effects of Irrigation Activation and Obturation Techniques on Pain After Root Canal Treatment
This randomized controlled clinical trial aimed to compare postoperative pain and analgesic use following single-visit root canal treatment performed using different final irrigation activation and root canal obturation…
- Trial name
- NCT07882368
- Testing
- Conventional Needle Irrigation, Sonic Irrigation Activation, Cold Lateral Condensation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Biruni University
Dental Caries, Teeth Loss
The Effect of Bitewing Radiography on Outcomes and Costs of Treating Caries in Permanent Teeth
Dentists commonly use bitewing radiographs (dental X-rays) together with a visual-tactile (clinical) examination to detect cavities between the back teeth.
- Conditions
- Dental Caries, Teeth Loss, Necrosis of Pulp, Irreversible Pulpitis
- Trial name
- BROCC (NCT07882693)
- Testing
- Visual-tactile caries examination, Visual-tactile caries examination and bilateral bitewing radiography
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jukka Leinonen
Pulpitis - Irreversible
Adjunctive Irrigation Strategies for Postoperative Pain After Full Pulpotomy
The goal of this clinical trial is to evaluate the effects of cryotherapy and dexamethasone on the intensity of postoperative pain in full pulpotomy procedures in permanent molars with symptomatic irreversible pulpitis.
- Trial name
- NCT07233577
- Testing
- Cryotherapy, Dexametasone
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Cukurova University
Symptomatic Irreversible Pulpitis, Postoperative Pain
Effect of Preoperative Video-Guided Breathing on Pain in Symptomatic Irreversible Pulpitis
The goal of this randomized controlled clinical trial is to evaluate whether a brief preoperative video-guided breathing exercise reduces postoperative pain in adults undergoing single-visit root canal treatment for symptomatic…
- Trial name
- NCT07859267
- Testing
- Video-Guided Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Cukurova University
Irreversible Pulpitis, Failed Inferior Alveolar Nerve Block
Articaine Versus Lidocaine for Supplemental Buccal Infiltration in Lower First Molars With Irreversible Pulpitis
Local anesthetic is used to numb a tooth before a root canal treatment. In lower back teeth with irreversible pulpitis (a painful, inflamed tooth nerve), the standard numbing injection near the jaw nerve, called an inferior…
- Trial name
- ARTLID-IP (NCT07869394)
- Testing
- Articaine 4% with epinephrine 1:100,000, Lidocaine 2% with Epinephrine 1:100,000
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Rehman Medical Institute - RMI
Pulpitis - Irreversible
Effect of Menstrual Phase on the Anesthetic Efficacy
The goal of this observational prospective clinical study is to learn whether the menstrual phase influences the anesthetic efficacy of inferior alveolar nerve block (IANB) in female patients aged 20-40 years with symptomatic…
- Trial name
- NCT07306533
- Testing
- Inferior Alveolar Nerve Block
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Jamia Millia Islamia
Pulpitis - Irreversible, Pulp Necroses
Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars
The aim of this study was to compare the clinical and radiographic success of conventional root canal treatment and lesion sterilisation tissue repair methods in deciduous molars with necrotic or irreversible pulpitis.
- Conditions
- Pulpitis - Irreversible, Pulp Necroses, Root Canal Infection
- Trial name
- NCT06811636
- Testing
- Lesion sterilization and tissue repair, Conventional pulpectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Irreversible Pulpitis, Apical Periodontitis
Success of Pulpotomy in Molars With Pulpitis With Periodontitis Detected Using AI and Those Without Periodontitis
Statement of problem: Although performing full pulpotomy in mature permanent molars with irreversible pulpitis showed success rates comparable to RCT, there is a growing need for further studies in order to determine the…
- Conditions
- Irreversible Pulpitis, Apical Periodontitis, Pulpitis
- Trial name
- NCT06767371
- Testing
- Patients with mature permanent molars diagnosed with severe pulpitis with apical periodontitis to be treated with full pulpotomy., Patients with mature permanent molars diagnosed with moderate pulpitis without apical periodontitis to be treated with full pulpotomy., Teeth with irreversible pulpitis
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Misr International University
Postoperative Pain After Endodontic Treatment, Oral Health-Related Quality of Life
Effects of Different Root Canal Filling Materials and Irrigation Agitation Techniques on Postoperative Pain in Teeth With Irreversible Pulpitis: A Randomized Clinical Trial
This clinical study is designed to evaluate the effects of different irrigation agitation techniques and root canal sealers on postoperative pain and oral health-related quality of life in patients with symptomatic irreversible…
- Conditions
- Postoperative Pain After Endodontic Treatment, Oral Health-Related Quality of Life, Symptomatic Irreversible Pulpitis, Endodontic Treatment
- Trial name
- NCT07859384
- Testing
- XP-Endo Finisher, EDDY, Passive Ultrasonic Activation
- Where
- Turkey (Türkiye)
- Volunteers
- 324 people
- Sponsor
- Ankara University
Molar Incisor Hypomineralisation, Irreversible Pulpitis
Pain Assessment Governing Partial or Full Pulpotomy of Immature Molars With Irreversible Pulpitis in Molar Incisor Hypomineralization
This randomized controlled clinical trial aims to evaluate and compare pain levels associated with partial pulpotomy (PP) and full pulpotomy (FP) in immature permanent first molars diagnosed with irreversible pulpitis.
- Conditions
- Molar Incisor Hypomineralisation, Irreversible Pulpitis, Immature Molars
- Trial name
- NCT07850986
- Testing
- pulpotomy for MIH affected immature PFMs, partial pulpotomy for MIH affected immature PFMs, pulpotomy for non-MIH affected immature PFMs
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Alaa Khafagy
Irreversible Pulpitis, Diabetes Mellitus, Type 2
Outcome of Complete Pulpotomy in Healthy and Type 2 Diabetic Patients in Permanent Teeth With Irreversible Pulpitis
Endodontic research on the effects of DM on pulp tissues is scarce. Diabetic human and animal histological research demonstrated a decreased reparatory response in the pulp, resulting in chronic pulp inflammation and reduced…
- Conditions
- Irreversible Pulpitis, Diabetes Mellitus, Type 2, Healthy
- Trial name
- NCT06586775
- Testing
- Pulpotomy
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Symptomatic Irreversible Pulpitis (SIP), Postoperative Pain After Endodontic Treatment
A Randomized Controlled Trial Evaluating Whether Pre-operative Trinase Reduces Post-operative Pain in Patients With Symptomatic Irreversible Pulpitis Compared to Placebo, Using VAS Scores and Analgesic Intake Over 48 Hours.
This study aims to determine whether Trinase, an enzyme-based anti-inflammatory medication, can reduce pain after root canal treatment in patients with symptomatic irreversible pulpitis.
- Conditions
- Symptomatic Irreversible Pulpitis (SIP), Postoperative Pain After Endodontic Treatment, Endodontic Disease, Dental Pain
- Trial name
- NCT07239505
- Testing
- Trinase
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Fayoum University
Symptomatic Irreversible Pulpitis and Post Operative Pain
Laser-Assisted vs Conventional Total Pulpotomy in Symptomatic Irreversible Pulpitis
his randomized controlled clinical trial will compare laser-assisted total pulpotomy with conventional total pulpotomy in permanent molar teeth diagnosed with symptomatic irreversible pulpitis.
- Trial name
- LASERPULP (NCT07850258)
- Testing
- Conventional Total Pulpotomy, Laser-Assisted Total Pulpotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- meliksahgunduz
Pulp Necrosis, Irreversible Pulpitis
CLINICAL AND RADIOGRAPHIC SUCCESS OF MODIFIED LSTR TECHNIQUES IN PRIMARY SECOND MOLARS
This study aimed to evaluate and compare the clinical and radiographic success of different antibiotic and vehicle modifications of the Lesion Sterilization and Tissue Repair (LSTR) technique in infected mandibular primary second…
- Trial name
- NCT07836686
- Testing
- 3Mix-MP Antibiotic Paste, 3Mix-NS Antibiotic Paste, 2Mix-MP Antibiotic Paste
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Uşak University