Clinical trials: Irritable Mood
Functional Abdominal Pain Disorder
Low-FODMAP Diet for Functional Abdominal Pain Disorders in Children.
This single-center, randomized, controlled, quadruple-blinded, superiority trial is performed to test the hypothesis that children with IBS and FAP-NOS who receive a low-FODMAP diet will have a lower mean abdominal pain intensity…
- Trial name
- NCT04528914
- Testing
- Low-FODMAP diet
- Where
- Poland
- Volunteers
- 42 people
- Sponsor
- Medical University of Warsaw
Attention Deficit and Disruptive Behavior Disorders, Marijuana Abuse
Divalproex Sodium (Depakote) for Explosive Tempers in Adolescents and Adults
The purpose of this study is to compare the effectiveness of divalproex sodium (Depakote) versus placebo in treating disruptive behavior disorder and explosive tempers in adolescents and adults.
- Trial name
- NCT00218114
- Testing
- Divalproex Sodium
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- New York State Psychiatric Institute
Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome
Peppermint Oil for the Treatment of Irritable Bowel Syndrome or Functional Abdominal Pain in Children: the MINT Study
Peppermint oil has shown to be effective in the treatment of Irritable Bowel Syndrome (IBS) symptoms in adults. Few studies of low quality are performed in an paediatric setting.
- Conditions
- Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome, Child, Adolescent
- Trial name
- MINT (NCT05799053)
- Testing
- Small intestinal release peppermint oil, Peppermint sweets
- Where
- 3 sites in Netherlands
- Volunteers
- 228 people
- Sponsor
- St. Antonius Hospital
Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction
Optimizing Research With Diverse Families - Feasibility and Acceptability Study (FAST)
Evaluate feasibility and acceptability of recruiting Black and Hispanic families for an open label clinical trial of multinutrients while collecting real-time parent-reported child behavior data and collecting at-home…
- Conditions
- Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction, Irritable Mood
- Trial name
- FAST (NCT06133231)
- Testing
- Multinutrients; a 36-ingredient blend of vitamins, minerals, amino acids, and antioxidants
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oregon Health and Science University
Irritable Bowel Syndrome (IBS), Functional Abdominal Pain
Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents
This protocol matches child subjects with peer mentors of similar age who have learned to function successfully with a chronic pain disorder.
- Conditions
- Irritable Bowel Syndrome (IBS), Functional Abdominal Pain, Fibromyalgia, Complex Regional Pain Syndrome (CRPS)
- Trial name
- NCT01118988
- Testing
- Mentorship
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Los Angeles
Bifidobacterium Adolescentis PRL2019, IBS
Gabapral in Pediatric IBS
Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disorder (FGID) characterized by recurrent episodes of defecation related abdominal pain associated with abnormal bowel habit.
- Conditions
- Bifidobacterium Adolescentis PRL2019, IBS, Pediatric
- Trial name
- NCT05737277
- Testing
- Gabapral
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliera "Sant'Andrea"
Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder
Characterization and Brain Mechanisms of Frustration in Youth With Severe Irritability or Attention Deficit Hyperactivity Disorder (ADHD)
Background: Irritability is an elevated proneness to anger. Children with irritability have difficulty tolerating frustration. They get angry and have temper outbursts more easily than their others their age.
- Conditions
- Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder, Normal Physiology
- Trial name
- NCT05357495
- Testing
- Affective Posner fMRI frustration induction task
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Autism
Oxcarbazepine Versus Placebo in Childhood Autism
The proposed study is designed to assess the effectiveness of treatment with Oxcarbazepine vs. placebo in childhood/adolescent autism.
- Trial name
- NCT00467753
- Testing
- Oxcarbazepine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Prebiotic, IBS (Irritable Bowel Syndrome)
Psyllium Husk in Pediatric IBS
Children aged 6 to 17 years with IBS will be randomly assigned to either receive psyllium husk supplementation in addition to usual care or receive usual care alone.
- Conditions
- Prebiotic, IBS (Irritable Bowel Syndrome), Psyllium, Quality of Life (QOL)
- Trial name
- NCT07880327
- Testing
- Psyllium Husk, Conventional therapy group
- Volunteers
- 70 people
- Sponsor
- Eman ElHaddad
Irritable Bowel Syndrome
Prevalence of Intestinal Parasitic Infections in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is common medical disorder and represent a group of diseases of the gastrointestinal tract that is characterized by chronic abdominal pain , bloating , passage of mucus or straining with bowel…
- Trial name
- NCT05830370
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Irritable Mood
RESist Against Irritability Superiority Trial
Irritability is defined as developmentally inappropriate proneness to anger. Irritability is a symptom of several mental health conditions in children and adolescents such as attention deficit hyperactivity disorder (ADHD)…
- Trial name
- RESIST (NCT05528926)
- Testing
- Non-Violent Resistance, Parent Management Training, Treatment As Usual
- Where
- France
- Volunteers
- 270 people
- Sponsor
- University Hospital, Montpellier
Irritable Bowel Syndrome, Gluten Sensitivity
Prevalence of Gluten Sensitivity in Irritable Bowel Syndrome: The First Study in Paediatrics.
Recently a new clinical entity, gluten sensitivity (GS), a form of gluten intolerance in which neither allergic nor autoimmune mechanisms can be identified, has been added to the spectrum of gluten-related disorders.
- Trial name
- GS-IBS (NCT02431585)
- Testing
- gluten
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Bari
Irritable Bowel Syndrome With Constipation (IBS-C)
4-Week, Multi-center Dose-Ranging Study for the IBS-C in Pts. 6 to <12 Yrs
This is a randomized, double-blind, placebo-controlled dose-ranging study to assess the safety and efficacy of tenapanor for treatment of the IBS-C in pediatric patients 6 to less than 12 year old.
- Trial name
- NCT06553547
- Testing
- Tenapanor
- Where
- 20 sites in United States
- Volunteers
- 72 people
- Sponsor
- Ardelyx
Irritable Bowel Syndrome
Probiotics in the Treatment of Irritable Bowel Syndrome
The aim of the present study is to assess the efficacy of two different probiotic products, lacto-fermented sauerkraut and the supplement Mutaflor, in the treatment of irritable bowel syndrome.
- Trial name
- NCT02953171
- Testing
- Raw, lacto-fermented sauerkraut, Mutaflor, Pasteurized sauerkraut
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- University of Copenhagen
Microbial Colonization, Gut Microbiota
Diet Supplementation With Prebiotics to Improve Gut Health in Egyptian Children
The study described herein seeks to assess the extent to which diet supplementation of young Egyptian children, one of the most vulnerable groups to the risk of diarrhea, with prebiotic fiber can improve their gut health.
- Trial name
- NCT06561724
- Testing
- Biscuits maltodextrin, Biscuits includes prebiotics tartoufa inulin, Biscuits includes prebiotics chicory inulin
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Irritable Bowel Syndrome
The FAIS-Trial: Faecal Microbiota Transplantation (FMT) in Adolescents With Refractory Irritable Bowel Syndrome (IBS)
A Double-blind randomised placebo-controlled pilot study as well as a reversed translational part To investigate whether two faecal transplantations from either allogeneic (healthy) or autologous (own) donor, administered through…
- Trial name
- FAIS (NCT03074227)
- Testing
- Allogeneic faecal transplantation, Autologous faecal transplantation
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Severe Mood Dysregulation
Characterization and Sequential Pharmacotherapy of Severe Mood Dysregulation
This project will characterize children and adolescents with severe mood dysregulation (SMD) and conduct a pilot study of combination pharmacotherapy as a basis for future intervention trials.
- Trial name
- NCT01714310
- Testing
- lisdexamfetamine, fluoxetine
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of California, Los Angeles
Irritable Bowel Syndrome
The Use of VSL#3 in Irritable Bowel Syndrome in Children
The goal of this study is to determine whether the oral administration of the probiotic VSL#3 under randomized, placebo-controlled conditions will improve symptoms of irritable bowel syndrome in children, safely.
- Trial name
- VSL#3 (NCT00932841)
- Testing
- VSL#3 900 billion bacteria, VSL#3 90 billion bacteria
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Dayton Children's Hospital
Abdominal Pain, Rectal Bloodloss
Head-to-head Comparison of Two Fecal Biomarkers to Screen Children for IBD
RATIONALE: A substantial proportion of children and teenagers with suspected inflammatory bowel disease (IBD) referred for endoscopy do not have the disease.
- Conditions
- Abdominal Pain, Rectal Bloodloss, Diarrhea, Inflammatory Bowel Disease
- Trial name
- CACATU (NCT02197780)
- Where
- 19 sites in Belgium, Netherlands
- Volunteers
- 355 people
- Sponsor
- University Medical Center Groningen
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh