Clinical trials: Keratoconjunctivitis
Vernal Keratoconjunctivitis
Topical Immuonosuppressant Drugs in Spring Catarrh
Spring catarrh is a prevalent type of conjunctival allergic disorder in temperate countries. Topical steroids are the cornerstone management of spring catarrh beside other anti allergic drugs.
- Trial name
- NCT04705584
- Testing
- Prednisolone (as Acetate), CycloSPORINE Ophthalmic Suspension, LTacrolimus Topical
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Assiut University
Keratoconjunctivitis Sicca
Efficacy Study of Cyclosporine Ophthalmic Emulsion in Patients With Dry Eye Disease
This study will evaluate the efficacy of cyclosporine ophthalmic solution vs. other non-prescription treatments in patients with dry eye disease.
- Trial name
- NCT00717418
- Testing
- cyclosporine ophthalmic emulsion 0.05%, artificial tears
- Where
- United States
- Volunteers
- 781 people
- Sponsor
- Allergan
Probiotic, Ocular Surface Disease
Efficacy and Safety of Oral Probiotics on Ocular Symptoms and Gut Microbiome of Children with Vernal Keratoconjunctivitis
The primary goal of this study is to determine the effects of oral probiotics on the severity of ocular symptoms and the alterations of the gut microbiome of children (4-18 years old) with vernal keratoconjunctivitis.
- Conditions
- Probiotic, Ocular Surface Disease, Ocular Diseases, Ocular Dryness
- Trial name
- NCT06793514
- Testing
- Probiotic
- Volunteers
- 32 people
- Sponsor
- Mohsen Pourazizi
Keratoconjunctivitis, Vernal
Efficacy Study of FK-506 and Cyclosporine in Vernal Keratoconjunctivits (VKC)
The study was a double-blind, parallel study to compare efficacy of 0.1% tacrolimus ophthalmic ointment vs 2% cyclosporine eye drops in children with vernal keratoconjunctivitis.
- Trial name
- NCT01068054
- Testing
- tacrolimus, cyclosporins
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Siriraj Hospital
Atopic Keratoconjunctivitis
Ocular Comorbidity in Atopic Dermatitis
A clinical characterization of a large cohort of patients with different severities of AD and ocular symptoms/atopic keratoconjunktivitis (AKC).
- Trial name
- NCT04973384
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Keratoconjunctivitis, Conjunctivitis
Phase III, Long-Term, Open-Label, Extension Study of 0.1% Tacrolimus(FK506) Ophthalmic Suspension in Patients With Vernal Keratoconjunctivitis
To investigate the long-term efficacy and safety of FK506 ophthalmic suspension in patients with vernal keratoconjunctivitis
- Trial name
- NCT00567918
- Testing
- FK506
- Where
- 8 sites in Japan
- Volunteers
- 52 people
- Sponsor
- Astellas Pharma Inc
Conjunctivitis, Vernal
HORMONES IN VERNAL KERATOCONJUNCTIVITIS
VKC is more common in males and tends to resolve with pubertal development. Clinical observation was not followed by an investigation that clarified whether there is a correlation between the hormonal pattern and the evolution of…
- Trial name
- HOR-VKC-2020 (NCT05038241)
- Where
- Italy
- Volunteers
- 88 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Vernal Keratoconjunctivitis
Evaluation of Central Corneal Thickness in Patients With Vernal Keratoconjunctivitis Using Topical Steroids
This prospective observational cohort study aims to assess changes in central corneal thickness (CCT) in vernal keratoconjunctivitis (VKC) patients using topical steroids.
- Trial name
- NCT06913790
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Superior University
Uveitis, Conjunctivitis
Ocular Manifestations in Rheumatic Diseases
This is a search strategy for determining the prevalence of ocular complications in inflammatory rheumatic diseases for the purposes of a meta analysis.
- Conditions
- Uveitis, Conjunctivitis, Keratoconjunctivitis Sicca, Xerophthalmia
- Trial name
- NCT03753893
- Testing
- No intervention used
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Keratoconjunctivitis Due to Adenovirus, Viral Shedding
A Placebo Controlled Comparison of Topical Zirgan Versus Genteal Gel for the Treatment of Adenovirus Conjunctivitis
The investigators are conducting this study because the patient have an eye infection which is called adenoviral conjunctivitis, and is the most common cause of "pink eye". There is currently no treatment for this condition.
- Trial name
- NCT01533480
- Testing
- Zirgan, genteal gel
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lifelong Vision Foundation
Vernal Keratoconjunctivitis
Cyclosporin A Eye Drop Treatment in Vernal Keratoconjunctivitis
This interventional study aims to evaluate the efficacy of Cyclosporine eye drop treatment in preventing relapses of Vernal Keratoconjunctivitis (VKC) and in treating the acute phases of the disease.
- Trial name
- NCT00426023
- Testing
- Cyclosporine A 0,05% eye drop, ketotifen fumarate 0.025% eye drops
- Where
- 3 sites in Italy
- Volunteers
- 48 people
- Sponsor
- Campus Bio-Medico University
Vernal Keratoconjunctivitis, Healthy Children
Cytokine Assay in Tears of Healthy Children and With Vernal Keratoconjunctivitis: Case Control Study and Monitoring of Cases at 6 Months
The ocular surface may be the seat of an inflammatory process in many pathology as vernal keratoconjunctivitis. It has been shown that inflammatory cytokines produced by the cells themselves and the constituent cells of the…
- Trial name
- NCT02057822
- Testing
- Cytokins assay in tears
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Dry Eye Syndromes
Effects of RP101 in Post-menopausal Women With Dry Eye Syndrome
The main purpose of this study is to establish whether RP101 can reduce symptoms of dry eye syndrome in post-menopausal women.
- Trial name
- NCT03821415
- Testing
- RP101
- Where
- 8 sites in Austria, Germany and 1 more
- Volunteers
- 104 people
- Sponsor
- Redwood Pharma AB
Microsporidia Keratitis, Microsporidial Keratoconjunctivitis
Application of Real-time PCR Platform for Detection of Vittaforma Corneae Among Patients With Microsporidia Keratitis
Diagnosis of patients with microsporiosis relies on pathological findings as well as laboratory detection of the causative organism.
- Trial name
- MK (NCT03551639)
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Keratoconjunctivitis Sicca, Sjogren's Syndrome
Treatment of Dry Eye Syndrome With Cyclosporin A Eye Drops
This study will examine whether cyclosporin A eye drops alleviate dry eye syndrome, a disorder of tear deficiency or excessive tear evaporation. The condition damages the surface of the eye and causes discomfort.
- Trial name
- NCT00001731
- Testing
- Cyclosporin A
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Eye Institute (NEI)
Vernal Keratoconjunctivitis, Atopic Keratoconjunctivitis
Dermatologic Tacrolimus Ointment on Eyelids in the Treatment of Refractory Vernal Keratoconjunctivitis and Atopic Keratoconjunctivitis
To evaluate the therapeutic effects of dermatologic tacrolimus ointment on eyelids to treat refractory vernal keratoconjunctivitis and atopic keratoconjunctivitis.
- Conditions
- Vernal Keratoconjunctivitis, Atopic Keratoconjunctivitis, Tacrolimus
- Trial name
- NCT03557203
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Keratoconjunctivitis
Corneal Topography in Vernal Keratoconjunctivitis
To evaluate the corneal topographic changes in VKC patients using Pentacam and prevalence of KC development in VKC.
- Trial name
- NCT06746467
- Testing
- pentacam
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Assiut University
Moderate to Severe Vernal Keratoconjunctivitis
A Study to Compare the Effectiveness and Safety of T1695 Versus Ciclosporin in Participants With Moderate to Severe Vernal Keratoconjunctivitis
The aim of the study is to Compare the Effectiveness and Safety of T1695 Versus Ciclosporin in Participants with Moderate to Severe Vernal Keratoconjunctivitis
- Trial name
- NCT07169695
- Testing
- Slit Lamp Examination, Far Best Corrected Visual Acuity (BCVA), T1695
- Where
- 11 sites in India
- Volunteers
- 120 people
- Sponsor
- Laboratoires Thea
Vernal Keratoconjunctivitis
3% Diquafosol Ophthalmic Solution for Active Moderate-to-Severe Vernal Keratoconjunctivitis
The aim of the study is to investigate whether patients with moderate-to-severe VKC and keratitis will benefit from the addition of Diquafosol ophthalmic solution in terms of symptoms and signs of VKC, tear film metrics, ocular…
- Trial name
- NCT06903884
- Testing
- 3% Diquafosol ophthalmic solution and 0.1% Cyclosporin A cationic ophthalmic emulsion, 0.1% Cyclosporin A cationic ophthalmic emulsion
- Where
- Hong Kong
- Volunteers
- 94 people
- Sponsor
- The University of Hong Kong
Ocular Rosacea, Keratoconjunctivitis
Clinical, Meibographic and Interferometric Evaluation of Phlyctenular Keratitis in Children - MEIBO-ROSACEE
The aim of this study is to describe the clinical, meibographic and interferometric manifestations of phlyctenular keratitis in children.
- Conditions
- Ocular Rosacea, Keratoconjunctivitis, Meibomian Gland Dysfunction
- Trial name
- MEIBO-ROSACEE (NCT03479853)
- Testing
- Ophthalmologic examination and meibographic and interferometric evaluation (Lipiview device)
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild