Clinical trials: L-PRF
Gingival Pigmentation
Effect of Injectable Platelet Rich Fibrin on Healing and Patient Satisfaction Following Laser Gingival Depigmentation
The objectives of the present study are to: 1. Evaluate the effect of I-PRF injection following laser gingival depigmentation technique on the healing period as a primary objective. 2.
- Trial name
- NCT05283668
- Testing
- i-PRF, Diode Laser
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Ain Shams University
Pulp Necrosis, Immature Permanent Teeth
PRF and CGF Scaffolds With EDTA in Regeneration
This study evaluated the regenerative outcomes of immature permanent teeth with necrotic pulps treated using three scaffold types-blood clot, platelet-rich fibrin (PRF), and concentrated growth factor (CGF)-combined with either…
- Conditions
- Pulp Necrosis, Immature Permanent Teeth, Open Apex, Periapical Periodontitis
- Trial name
- RET-EDTA-CGF (NCT07265804)
- Testing
- Blood Clot + 5% EDTA, Blood Clot + 17% EDTA, PRF + 5% EDTA
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Lateral Sinus Lifting
Lateral Sinus Augmentation Utilizing Bovine Bone Mixed with Platelet-rich Fibrin
Background: In sinus augmentation procedure, graft resorption remains a major dilemma of various graft materials. Objective: To estimate the graft volume changes following lateral sinus augmentation utilizing cone beam computed…
- Trial name
- NCT06810921
- Testing
- lateral sinus lift
- Where
- Iraq
- Volunteers
- 34 people
- Sponsor
- University of Baghdad
Dental Pulp Necroses
Efficacy of Regenerative Endodontic Treatment With PRF as a Secondary Treatment of Mature Necrotic Incisors in Adolescents
Evalaution of clinical success of secondary treatment for total 40 permanent incisors with failed root canal treatment with apical radiolucency.
- Trial name
- PRF (NCT05517187)
- Testing
- no intervention, Platelet rich fibrin
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nahda University
Anastomotic Leak, Platelet-Rich Fibrin
Leukocyte and and Platelet-rich Fibrin Plasma for the Prevention of Anastomotic Leakage in Colorectal Anastomosis
Anastomotic leak rate in colorectal surgery is estimated between 4 and 20 percent. Leukocyte and and platelet-rich fibrin plasma (L-PRF) is second generation platelet concentrate whose application in colorectal anastomosis in…
- Conditions
- Anastomotic Leak, Platelet-Rich Fibrin, Colorectal Surgery
- Trial name
- NCT05264467
- Testing
- Platelet rich fibrin on colorectal anastomosis
- Where
- Chile
- Volunteers
- 106 people
- Sponsor
- Universidad de Concepcion
A-PRF, ALLOGRAFT
Sticky Bone Compared to A-PRF(Platlet Rich Fibrin) Effect on Alveolar Ridge Preservation
In this research investigators are going to detect the effect of using different type of materials(sticky bone\platlet rich fibrin ) compared to normal healing on the dimensional changes of alveolar crest after single rooted…
- Trial name
- NCT05536492
- Testing
- A-PRF, ALLOGRAFT
- Where
- Palestinian Territories
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Arab American University (Palestine)
Maxillary Sinus
PRF Versus Advanced PRF in Sinus Augmentation
In the present study the main hypothesis , Advanced PRF will improve the bone quality and quantity in sinus augmentation
- Trial name
- NCT05134753
- Testing
- Advanced PRF, Control
- Volunteers
- 32 people
- Sponsor
- Cairo University
Oral Ulcer Due to Pemphius Vularis, Oral Ulcer Due to Benign Mucous Membrane Pemphioid
PRF in Management of Chronic Multiple Oral Ulcers
PRF in orabase will be applied as a pack material on chronic oral ulcers of chronic multiple oral lesions compared to conventional topical steroid therapy with clobetasol propionate 0.05% in orabase.
- Conditions
- Oral Ulcer Due to Pemphius Vularis, Oral Ulcer Due to Benign Mucous Membrane Pemphioid, Oral Ulcer Due to Steven Johnson's Syndrome
- Trial name
- NCT03878771
- Testing
- Platelet rich fibrin gel in Orabase, Dermovate cream in Orabase
- Where
- Egypt
- Volunteers
- 804 people
- Sponsor
- Beni-Suef University
Fibrin/Therapeutic Use, Blood Platelets
Effects of the Use of Platelet-rich Fibrin on Bone Regeneration After Impacted Third Molar Surgery
The purpose of this study is to evaluate the bone regeneration after impacted third molar surgery on split mouth design using platelet-rich fibrin.
- Conditions
- Fibrin/Therapeutic Use, Blood Platelets, Molar, Third, Bone Regeneration
- Trial name
- NCT02890680
- Testing
- Platelet-rich fibrin, Control group
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Necrotic Immature Permanent Teeth, Regenerative Endodontic Treatment
Application of Advanced Platelet-Rich Fibrin Plus (A-PRF+) in Revascularisation of Necrotic Immature Permanent Teeth
The goal of this clinical trial is to evaluate the effectiveness of an advanced platelet-rich fibrin plus (A-PRF+) revascularization procedure to promote healing and root development in necrotic immature permanent single-rooted…
- Conditions
- Necrotic Immature Permanent Teeth, Regenerative Endodontic Treatment, Pulp Regeneration, Root Maturation
- Trial name
- A-PRF+ (NCT07092488)
- Testing
- Advanced Platelet-Rich Fibrin Plus (A-PRF+) Revascularization Procedure
- Where
- Croatia
- Volunteers
- 28 people
- Sponsor
- University of Zagreb
Pulpitis
The Use of Platelet-Rich Fibrin in Partial Pulpotomy Procedure
The aim of this study is to evaluate the clinical and histological pulp responses when MTA and a combined of MTA/PRF is used as pulp-capping agents after partial pulpotomy.
- Trial name
- NCT04331964
- Testing
- partial pulpotomy
- Where
- Syria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Damascus University
Periodontitis
L-PRF Plus Non Surgical Periodontal Treatment
Abstract: Background: Leucocyte and Platelet-Rich Fibrin (L-PRF) has shown to promote regenerative processes, even reporting antibacterial effect.
- Trial name
- NCT04520438
- Testing
- Leukocyte and platelet rich fibrin, Non-Surgical Periodontal treatment
- Where
- Chile
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Osteoarthritis
Platelet Rich Plasma Combined With Platelet Rich Fibrin in Management of Temporomandibular Joint Osteoarthritis
Studying effectiveness of prp with prf comparing with prp or prf for mangement of tmj osteoarthritis as result in pain and mandibular movement in adult pt
- Trial name
- NCT06573502
- Testing
- Prp with prf or prp or prf
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Aliaa Babekir Ahmed Mohamed
Effects of; Movement of Teeth Assiste Wit MOPS and I-prf
Maxillary Canine Retraction Assisted With Micro-osteoperforations Versus Injectable Platelet Rich Fibrin
The present clinical comparative study will be undertaken for assessment of two different modalities of maxillary canine retraction assisted with microosteoperforations versus injectable platelet rich fibrin.
- Trial name
- NCT05960825
- Testing
- injectable platelet rich fibrin versus microosteoperforation
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Direct Pulp Capping
Clinical and Radiographic Assessment of Platelet Rich Fibrin and Mineral Trioxide Aggregate as Pulp Capping Biomaterials
eligible carious teeth with exposed pulp by the undergraduate students will be randomly divided into two groups to be treated with direct pulp capping (A), where (A1) represents the comparator group where teeth will be treated…
- Trial name
- NCT04488679
- Testing
- direct pulp capping
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Rahma Ahmed Ibrahem Hafiz
Effect of Piezocision and Injectable Platelets Rich Fibrin on Tooth Movement
Evaluation of Piezocision Versus Injectable Platelet-rich Fibrin During Orthodontic Canine Retraction Orthodontic Canine Retraction: A Comparative Clinical Study
Comparison of piezocisin and injectable platelets rich fibrin during canine retraction
- Trial name
- NCT07239024
- Testing
- Iprf and piezocision
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Pulpitis - Irreversible, Tooth Decay
Efficacy of PRF and MTA as Compared to Calcium Hydroxide for Pulpotomy in Human Irreversibly Inflamed Permanent Teeth
Of all the various pulpotomy medicaments that have been studied till to date, three agents have been selected for this study to compare their efficacy.
- Trial name
- NCT05266859
- Testing
- Calcium hydroxide, MTA, PRF
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Liaquat College of Medicine and Dentistry
Periodontitis
Efficacy of PRF Application on Clinical Parameters and GCF Platelet-derived Growth Factor-BB and Periostin Levels
Determine the efficacy of the non-invasive application of PRF on periodontal clinical parameters(pocket reduction) and the levels of PDGF-BB and Periostin in the gingival crevicular fluid.
- Trial name
- NCT05178771
- Testing
- Platelet rich fibrin
- Where
- Iraq
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Gingival Recession Types One(RT1), Gingival Crevicular Fluid
Comparison of Connective Tissue and PRF in Gingival Recession
Aim: In this study, it was aimed to comparatively investigate the clinical and biochemical effects of subepithelial connective tissue graft and coronally advanced flap (SCTG + CAF) or titanium-prepared platelet rich fibrin and…
- Trial name
- NCT07877064
- Testing
- Titanium-prepared Platelet-Rich Fibrin, SCTG + CAF
- Volunteers
- 22 people
- Sponsor
- Ataturk University
Chronic Periodontitis
Applied The Platelet Rich Fibrin in Chronic Periodontitis
Platelet rich fibrin is a second generation platelet concentration which contains various growth factors. The aim of this study is to evaluate the clinical and biochemical efficacy of PRF in subjects of chronic periodontitis in…
- Trial name
- NCT02594605
- Testing
- Platelet Rich Fibrin, Conventional Flap Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ataturk University