Clinical trials: LGBTQ
HIV Infections
PrEP2Prevent An Online PrEP Navigation and Activation Intervention
The goal of this clinical trial entitled, PrEP2Prevent: An Online PrEP Navigation and Activation Intervention for YMSM, is to develop and test a method for supporting access to an HIV prevention medication called Pre-Exposure…
- Trial name
- P2P (NCT05281393)
- Testing
- PrEPresent
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
LGBTQ, Sexual Behavior
Developing Online Interventions to Reduce Stigma-Related Stress, Sexual Health, and HIV Risk Among Young Chinese MSM
This study is a 2-arm RCT that will assess the efficacy of a culturally adapted, 10-session SGM-affirmative, internet-based cognitive behavioral therapy (iCBT) among young men who have sex with men (YMSM) in Hunan province China.
- Conditions
- LGBTQ, Sexual Behavior, HIV Risk
- Trial name
- NCT04718194
- Testing
- ESTEEM iCBT, Self-monitoring control
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
Bullying of Child
Evaluation of an Online Intervention to Help LGBTQ Youth Cope With Bullying
The purpose of this research study is to conduct a pilot randomized controlled trial of a game-based intervention is able to increase help-seeking-related knowledge, attitudes, and behaviors, reduce health risk factors/behaviors…
- Trial name
- NCT03501264
- Testing
- Online Game, LGBTQ Resources
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Pittsburgh
Self-Harm, Suicidal
Co-Producing LGBTQ-Affirmative DBT Protocols.
Aims: 1. To co-produce new intervention parts that meet the needs of LGBTQ+ people at risk of self-harm or suicidal thoughts, with LGBTQ+ people and DBT therapists.
- Conditions
- Self-Harm, Suicidal, Emotional Dysregulation
- Trial name
- NCT06966193
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College London
HIV/STI Incidence, Communication About Health Information
The Gender Inclusive Sexuality Talks Program
The study is centered on helping parents answer and meet the sexuality-specific questions and needs of transgender, gender diverse, lesbian or bisexual female youth.
- Trial name
- GIST (NCT07825571)
- Testing
- The Gender Inclusive Sexuality Talks Program, GIST Control
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pennsylvania
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Sexual Harassment, Anti-Gay Bias
Effectiveness Study of the Intervention "Stop Sexual Harassment" in Secondary School
"Stop sexual harassment" is a school based intervention tailored to reduce sexual- and gendered harassment among pupils in secondary school.
- Conditions
- Sexual Harassment, Anti-Gay Bias, Non Sexual Harassment, Gender-based Violence
- Trial name
- NCT04716400
- Testing
- Stop sexual harassment
- Where
- Norway
- Volunteers
- 2,037 people, healthy volunteers welcome
- Sponsor
- NORCE Norwegian Research Centre AS
Vaping, Adolescent Behavior
Social Media Anti-Vaping Messages to Reduce ENDS Use Among Sexual and Gender Minority Teens
The investigators long-term goal is to reduce tobacco use and tobacco-related health disparities among SGM populations. The objective of Project SMART (Social Media Anti-Vaping Messages to Reduce ENDS Use Among Sexual and Gender…
- Conditions
- Vaping, Adolescent Behavior, Communication Research
- Trial name
- SMART (NCT06308081)
- Testing
- Tailored
- Where
- United States
- Volunteers
- 1,155 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
LGBTQ, Racial Disparities
Lakota Family Acceptance Project
The goal of this open pilot trial (OPT) is to develop a Lakota-adapted Family Acceptance Project (LFAP) for Indigenous 2SLGBTQ+ youth and their caregivers.
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- L-FAP OPT (NCT07326748)
- Testing
- Adapted Lakota Family Acceptance Program
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Michigan
LGBTQ, Racial Disparities
Lakota Family Acceptance Project Pilot RCT
Although research documents the concerning rates of mental and behavioral health problems (e.g., substance use/initiation) among Indigenous LGBTQ2S+ youth, there is very little known about how to prevent these deleterious issues…
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- L-FAP (NCT07865858)
- Testing
- Adapted Lakota Family Acceptance Program
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Suicide
Implementing Evidence Informed Practices in Schools to Address LGBTQ Adolescent Suicide
Reducing youth suicide in the U.S. is a national public health priority. Sexual and gender minority adolescents are at elevated risk for suicide. Safer school environments, however, can decrease this risk.
- Trial name
- RLAS (NCT02875535)
- Testing
- RLAS
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Aggression, Adolescence
Wise Intervention for Reducing Aggressive Behaviors and Promoting Prosocial Behaviors Toward LGB-TNB Individuals
This study evaluates the effectiveness of a wise Intervention to reduce aggressive behaviors and promote prosocial behaviors toward LGB-TNB individuals among Spanish adolescents.
- Trial name
- LGB-TNB (NCT07212283)
- Testing
- Wise Intervention LGB-TNB, Values alignment wise intervention
- Where
- Spain
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Deusto
LGBTQ, Sexual Behavior
A Trial of Online LGBTQ-affirmative Cognitive Behavioral Therapy to Reduce Depression and Associated Health Risks Among Young Adults
This study is to test the efficacy of an online CBT intervention (EQuIP) that addresses the pathways through which minority stress compromises LGBTQ young adults' co-occurring mental (e.g., depression) and behavioral (e.g.…
- Trial name
- NCT04408469
- Testing
- Online EQuIP, Self-monitoring control
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
Parkinson Disease, Sexual Orientation
Perspectives on Healthcare Access and Equity of People With Parkinson's Disease Identifying as LGBTQ+
Study Rationale: Older adults who identify as lesbian, gay, bisexual, transgender, or queer (LGBTQ+) have worse health than non-LGBTQ+ older adults.
- Trial name
- LGBTQ+_PD (NCT05502055)
- Testing
- Individual interviews, Focus Groups, National Survey
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Creighton University
CBT, LGBTQ
SGM Evidenced-Based Mental Healthcare Implementation
The purpose of the proposed study is to identify effective strategies for implementing lesbian, gay, bisexual, transgender, and queer (LGBTQ)- affirmative Cognitive-Behavioral Therapy (CBT) at LGBTQ community centers across the…
- Trial name
- NCT05890404
- Testing
- LGBTQ-Affirmative CBT Training: Materials Only, LGBTQ-Affirmative CBT Training: Direct Training, LGBTQ-Affirmative CBT Training: Local Supervision
- Where
- United States
- Volunteers
- 1,379 people, healthy volunteers welcome
- Sponsor
- Yale University
Sexual Minority Stress Experiences Among LGBTQ Youth
Feasibility of a Multi-Level School Intervention for LGBTQ Youth
The goal of this R21 grant is to test the feasibility of a theoretically informed, LGBTQ-affirming intervention (Proud \& Empowered; P\&E).
- Trial name
- NCT04041414
- Testing
- Proud & Empowered!
- Where
- 4 sites in United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Teen Pregnancy, STD Prevention
Evaluation of the Impact of the IN•Clued Curriculum: An LGBTQ Sex ed Program
The INclued program was implemented in 16 states across the US. The purpose of this study is to measure: Nine months after the end of the program and one year after the workshop, are IN•clued participants less likely to report…
- Trial name
- NCT04494477
- Testing
- The IN•clued program
- Where
- United States
- Volunteers
- 1,401 people, healthy volunteers welcome
- Sponsor
- Philliber Research & Evaluation
Anxiety Disorders, Depression
LGBTQ-affirmative CBT for Youth
This study will adapt LGBTQ-affirmative cognitive behavior therapy (CBT) - previously only used with adults - for youth aged 12-17 years.
- Conditions
- Anxiety Disorders, Depression, LGBTQ
- Trial name
- NCT05408858
- Testing
- LGBTQ-affirmative cognitive behavioral group therapy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Yale University
LGBTQ, Racial Disparities
Family Acceptance Project Online (Pilot RCT)
Research shows that sexual and gender minority youth (SGMY) experience high rates of mental health problems and other challenges (e.g., social, academic).
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- FAP-O (NCT06839859)
- Testing
- Family Acceptance Project - Online
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Suicide, Self-Injurious Behavior
Youth Empowerment and Safety Intervention
This clinical trial will implement and evaluate the feasibility, acceptability, and initial impact of Peer Support Specialist (PSS) services for public system-involved sexual and gender minority (lesbian, gay, bisexual, queer…
- Trial name
- YES (NCT07214233)
- Testing
- Treatment as Usual, Peer Support Services (PSS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Case Western Reserve University