Clinical trials: Labor and Delivery Complication
Preterm Birth
Which Needs for Premature New-born Babies' Parents Facing Environmental and Social Difficulties ?
This study aims to understand parents' needs regarding social difficulties faced in a child's preterm birth context.
- Trial name
- PrémaSoin (NCT03394443)
- Testing
- Semi-structured interviews
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Premature, Respiratory Distress Syndrome in Premature Infant
Novel Low Cost Bubble CPAP as an Alternative Respiratory Support in Low Resource Setting
This is a single-blind randomized controlled trial done in a Level III neonatal intensive care unit. Preterm newborns with RDS were randomized to receive oxygen therapy through bubble CPAP vs ventilator-derived CPAP.
- Trial name
- NCT06082674
- Testing
- Vayu bCPAP, Mechanical Ventilator Driven CPAP
- Where
- Philippines
- Volunteers
- 70 people
- Sponsor
- Ilocos Training and Regional Medical Center
Neonatal Intensive Care, Music Therapy
The Effect of Lullaby Listened to Preterm Babies in Neonatal Intensive Care Units on Physiological Parameters and Pain
Preterms who enter a different environment after the intrauterine period experience an adaptation process and may need special care due to conditions such as developmental disabilities or neurological disorders.
- Conditions
- Neonatal Intensive Care, Music Therapy, Pain Responses
- Trial name
- NCT05253625
- Testing
- Listening to a recorded lullaby.
- Volunteers
- 93 people
- Sponsor
- Izmir Tinaztepe University
Preterm Infant
Effect of Kinesiotaping Application in Preterm Infants Undergoing Noninvasive Ventilation
Kinesiotaping (KT) applied to the thorax is believed to enhance breathing by supporting the respiratory muscles. Infants born premature usually have respiratory problems because of depletion of surfactant and respiratory muscle…
- Trial name
- NCT03660358
- Testing
- kinesiotape application
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Baskent University
Preterm Birth
Comparison of Early Caffeine Administration Vs Supportive Therapy in Preventing Acute Kidney Injury
Recent observational data point towards a reduced incidence of acute kidney injury (AKI) with early caffeine use, but high-quality randomized controlled trials comparing early caffeine initiation to supportive therapy alone are…
- Trial name
- NCT07305935
- Testing
- Caffeine, Supportive care
- Where
- Pakistan
- Volunteers
- 236 people
- Sponsor
- Muhammad Aamir Latif
Necrotizing Enterocolitis, Premature Birth
Cohort of Premature Newborns for Charaterization of the Digestive Microbiota in Ulcerative Necrotizing Enterocolitis in Premature Infants
Compare the bacterial digestive microbiota during the stay in neonatal intensive care between a group of premature newborns developing a NEC (necrotizing enterocolitis) and a group of newborns free from NEC.
- Trial name
- CortECS (NCT04972734)
- Testing
- premature newborns developing a NEC, premature newborns without NEC
- Where
- France
- Volunteers
- 297 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pre-Term, Body Temperature Changes
Early Weaning of Preterm Newborn From Incubator to Cot at 1400 Grams
Background: To maintain the body temperature of preterm newborns is one of the essential criteria for discharge from hospital. Aim: we aimed to assess the feasibility and the safety of an early weaning protocol from incubator to…
- Conditions
- Pre-Term, Body Temperature Changes, Transition, Patient Discharge
- Trial name
- NCT04351425
- Testing
- Weaning to crib, Weaning from incubator
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
Blood Group Antigen Abnormality, Prematurity
Association Between Different Blood Groups and Sepsis in Preterm Infants
To investigate whether there is a relationship between sepsis and blood groups in preterm infants.This retrospective cohort study included preterm neonates born at <32 weeks of gestation with a birth weight <1500 g.
- Conditions
- Blood Group Antigen Abnormality, Prematurity, Sepsis
- Trial name
- NCT03734978
- Testing
- Diagnosis
- Where
- Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Ufuk Cakir
Premature Birth
Balanced Anesthesia for Intubation of Premature Infants
The study aim is to compare a balanced anesthesia of the medicines used in all other age groups with the routine premedication in use for premature's with regards to the success in the intubation procedure, the need for analgesia…
- Trial name
- NCT00216944
- Testing
- Tracheal intubation for respiratory care in preterm infants
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Lund University Hospital
Apnea of Prematurity, Prematurity
Nasal Olfactory Stimulation and Its Effect on Respiratory Drive in Preterm Infants
This trial analyzes the effect of an olfactory stimulation with vanilla or strawberry aroma compared to placebo on desaturations and bradycardia in preterm infants with apnea of prematurity.
- Conditions
- Apnea of Prematurity, Prematurity, Infant, Premature, Diseases
- Trial name
- NOSE (NCT05878925)
- Testing
- Aroma
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Zurich
Very Preterm Infants, Zinc Deficiency
Higher and Standard Doses of Enteral Zinc Supplementation in Very Preterm Infants
The goal of this randomized clinical trial is to compare the effect of higher (10 mg per day) versus standard (1 mg per day) doses of zinc supplementation The main questions it aims to answer are: Growth velocities and delta…
- Trial name
- ZnVeryPT (NCT06219525)
- Testing
- Higher dose of enteral zinc, Standard dose of enteral zinc
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Prince of Songkla University
Preterm Labor, Premature Birth
Comparison Between Natural Progesterone and Vaginal Pessary for the Prevention of Spontaneous Preterm Birth
The aim of this study is to compare the effectiveness between the cervical pessary and the natural progesterone in reduction of preterm birth rates in pregnant women with a uterine cervical length of 25 mm or less evaluated by…
- Trial name
- PAP-C (NCT02511574)
- Testing
- natural progesterone, cervical pessary
- Where
- Brazil
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Preterm Birth
Maternal Anxiety Related to How the Pediatrician Provided Prenatal Information About Preterm Birth
Women hospitalized for preterm labor require clear information about prematurity. This study assessed whether or not specific written information about prematurity delivered at admission to the unit combined with an oral…
- Trial name
- Infoprema (NCT03646578)
- Testing
- State of anxiety
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pregnancy, Preterm Birth
A RCT of CenteringPregnancy on Birth Outcomes
The purpose of this study is to evaluate whether CenteringPregnancy group prenatal care can improve preterm birth rate and other birth outcomes, maternal psychosocial and behavioral outcomes, and decrease the racial difference in…
- Trial name
- CRADLE (NCT02640638)
- Testing
- CenteringPregnancy
- Where
- 4 sites in United States
- Volunteers
- 2,350 people
- Sponsor
- Clemson University
Anemia, Neonatal, Necrotizing Enterocolitis
Alteration of Stool Microbiota in Preterm Infants With Anemia
This study evaluates the relationship between anemia and stool microbiota in premature infants. It also evaluates the relationship between blood transfusion and stool microbiota.
- Conditions
- Anemia, Neonatal, Necrotizing Enterocolitis, Dysbiosis
- Trial name
- NCT03554278
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Prematurity
Effects of a Parenting Skills Training Program on Maternal Self-Efficacy, Perceived Social Support, and Infant Development in Mothers of Preterm Infants Aged 6-12 Months
The goal of this clinical trial is to evaluate whether a structured parenting skills training intervention can improve maternal parenting self-efficacy, perceived social support, and infant developmental outcomes in mothers of…
- Trial name
- NCT07468435
- Testing
- Parental Skill Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Medipol University
Patent Ductus Arteriosus, Preterm Infant
Randomized Controlled Trial to Evaluate the Safety and Efficacy of Acetaminophen in Preterm Infants Used in Combination With Ibuprofen for Closure of the Ductus Arteriosus
The purpose of the present study is to determine whether treatment of hemodynamically significant patent ductus arteriosus with a combined therapy of intravenous Ibuprofen and oral acetaminophen has higher success rate in closing…
- Conditions
- Patent Ductus Arteriosus, Preterm Infant, Bronchopulmonary Dysplasia
- Trial name
- NCT03701074
- Testing
- Ibuprofen and acetaminophen
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of South Alabama
Very Low Birth Weight Infant, Respiratory Distress Syndrome in Premature Infant
Enteral Nutrition Tolerance And REspiratory Support (ENTARES)
This research study aims to evaluate the relation between non-invasive ventilation and feeding tolerance in preterms with respiratory distress syndrome (RDS).
- Conditions
- Very Low Birth Weight Infant, Respiratory Distress Syndrome in Premature Infant, Enteral Feeding Intolerance
- Trial name
- ENTARES (NCT03548324)
- Testing
- HHHFNC, NCPAP
- Where
- 13 sites in Italy
- Volunteers
- 280 people
- Sponsor
- University of Turin, Italy
Preterm Infant, Oral Feeding Performance
Effects of Prefeeding Oral Stimulation on Feeding Performance in Preterm Infants
The objective of this study is to evaluate the efficacy of an oral stimulation program on the length of the transition period in preterm infants (primary outcome), the length of hospital stay and the breastfeeding rates at…
- Trial name
- NCT01649362
- Testing
- prefeeding oral stimulation program
- Where
- Luxembourg
- Volunteers
- 101 people
- Sponsor
- Centre Hospitalier du Luxembourg
Extreme Prematurity
Preterm Erythropoietin Neuroprotection Trial (PENUT Trial)
Recombinant human erythropoietin (Epo) is a promising novel neuroprotective agent. Epo decreases neuronal programmed cell death resulting from brain injury; it has anti-inflammatory effects, increases neurogenesis, and protects…
- Trial name
- PENUT (NCT01378273)
- Testing
- Epo, Control
- Where
- 19 sites in United States
- Volunteers
- 941 people
- Sponsor
- University of Washington