Clinical trials: Labour
Labour Duration
Intravenous Paracetamol Versus Intramuscular Tramadol in Shortening the Duration of Labour.
It is a well established fact that the pain of labour can be excrutiating and ways to shorten the duration of labour has been sought after.
- Trial name
- NCT07394491
- Testing
- paracetamol, Tramadol hydrochloride
- Where
- Nigeria
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Federal Teaching Hospital Abakaliki
Gestational Diabetes, Hypoglycemia, Neonatal
Glucose Control During Labour in Gestational Diabetes Mellitus With Insulin Treatment: A Randomized Controlled Trial
Pregnant women with gestational diabetes who are treated with insulin and their daily insulin dose is 30 IU or more will be randomized into two groups. Active treatment group will receive insulin-glucose-infusion during labour.
- Trial name
- NCT02590016
- Testing
- Insulin, Aspart
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Hydration
Bioimpedance In Pregnancy and Labour: A Fluid Balance Concept Study.
The purpose of our study is to find out if using a simple bed side test can tell us information about changes that occur in women's body water content.
- Trial name
- BiPAL (NCT03823820)
- Testing
- Bioimpedance Analyser
- Where
- United Kingdom
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Birth Injuries
The Effect of Primary Delivery of the Anterior Compared With the Posterior Shoulder on Perineal Trauma: a Randomized Controlled Trial
It is unknown if primary delivery of the anterior or the posterior shoulder causes less perineal tear. The objective of this trial is to evaluate the incidence and degree of perineal trauma after primary delivery of the anterior…
- Trial name
- NCT01937546
- Testing
- Primary delivery of anterior shoulder, Primary delivery posterior shoulder
- Where
- Denmark
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Holbaek Sygehus
Labour; Induced, Pilot Study
High Volume Foleys Increasing Vaginal Birth Pilot Trial
It is currently unknown if there is a way to decrease the risk of cesarean delivery when undergoing cervical ripening and induction of labour.
- Conditions
- Labour; Induced, Pilot Study, Cervical Ripening
- Trial name
- NCT02993432
- Testing
- Foley catheter filled to 80cc, prostaglandin of the clinician's choice
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Stillbirth, Neonatal Death
Intermittent Auscultation Using Handheld Doppler: a Randomized Controlled Trial Comparing Perinatal Outcomes in Uganda
A novel handheld Doppler has been developed which is rugged and is powered only by a hand crank. This study aims to test the use of this Doppler versus the Pinard horn to monitor the fetal heart rate in labour in a hospital…
- Trial name
- NCT02273037
- Testing
- Fetal heart rate Doppler, Partograph
- Where
- 2 sites in Canada, Uganda
- Volunteers
- 1,987 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Labor, Induced
Sublingual Misoprostol for Induction of Labor
The purpose of this study is to compare effectiveness and safety of a sublingual misoprostol 12,5 mcg with vaginal misoprostol 25 mcg for induction of labour with an alive and term fetus.
- Trial name
- SUBMISO (NCT01406392)
- Testing
- Misoprostol 25mcg, Sublingual Misoprostol
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Induction of Labour, Labour, Induced
Misoprostol Labour Induction Study
Labour induction is a frequent obstetric intervention (~20%). Prostaglandins (PGs) are effective agents, but gastrointestinal (GI) intolerance has limited use to non-oral routes.
- Trial name
- NCT03489928
- Testing
- Oral Misoprostol, Vaginal Misoprostol, Dinoprostone
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- David Young
Epidural, Analgesia
Epidural Analgesia and Delivery of Second Twin
Over an 8-year period, 124 twin pregnancies at gestational age ≥32 weeks with both twins presenting as a vertex and eligible for vaginal delivery were reviewed.
- Conditions
- Epidural, Analgesia, Labor Pain
- Trial name
- Epidural (NCT04608006)
- Testing
- Bupivacaine-fentanyl
- Where
- Egypt
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Abdelrady S Ibrahim, MD
Labor Pain, Birth, First
Labour Pain and Birth-Specific Stereogram Cards (BSSC)
Background: Reducing the perception of labour pain is important to reduce the negative consequences of labour pain and to increase women's satisfaction with the birth experience.
- Trial name
- NCT05386004
- Testing
- Birth-Specific Stereogram Cards (BSSC)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Atlas University
Labor Pain
The Response Patterns to the Electrical Stimulation of Epidural Catheters With Varying Pulse Widths in Term Pregnant Women
Epidural analgesia is commonly used for labor pain relief due to its safety and effectiveness. Despite a very high success rate, the epidural technique remains a somewhat blind technique and failures continue to occur.
- Trial name
- NCT02762149
- Testing
- Nerve stimulator
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pregnancy
Home Based Life Saving Skills Training in a Rural Area in Tanzania
Background The maternal mortality ratio in Tanzania has been persistently high for ten years with no signs of the ratio going down.The Tanzania Demographic and Health Survey (TDHS) of 1999 and 2005 estimate the maternal mortality…
- Trial name
- HBLSS (NCT01192646)
- Testing
- HBLSS
- Where
- Tanzania
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Muhimbili University of Health and Allied Sciences
Microbial Colonization
Comparing Impacts of Donor Human Milk to Formula Supplementation on the Gut Microbiome of Full-term Infants
The goal of this pilot randomized controlled trial (RCT) is to examine donor human milk (DHM) as a clinical intervention targeted at achieving beneficial microbiome signatures in full-term infants who are exposed to intrapartum…
- Trial name
- PPDHM (NCT05815433)
- Testing
- Donor Human Milk - Nutritional Replacement
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Latent Phase Labour
Early Labour Assessment and Support at Home
To determine, among healthy first time mothers who are uncertain as to when to come to hospital in labour, if home visits by obstetrical nurses compared to telephone advice have an impact on reducing cesarean section rate.
- Trial name
- NCT00225329
- Testing
- Labour assessment and support
- Volunteers
- 1,466 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Work-Related Condition
Child Labour at Al-Sadat Neighborhood, Assiut City
General objective: To promote proper health status of working children in Assiut city. Specific objectives: 1. To describe the socio-demographic characteristics of children working in car repair workshops in Al-Sadat area of…
- Trial name
- NCT03588858
- Testing
- structured interview questionnaires
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hisham Ragab Ali
Post Partum Hemorrhage
Misoprostol Versus Oxytocin for Prevention of Post Partum Hemorrhage
Post partum Hemorrhage (PPH) is one of three main causes of death in pregnant women. Oxytocin is widely used for prevention of PPH. Some studies suggested misoprostol as an alternative treatment when Oxytocin isn't available.
- Trial name
- NCT01863706
- Testing
- Misoprostol, Oxytocin
- Where
- Iran
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hormozgan University of Medical Sciences
Preterm Labor
Impact of Suspected Preterm Labour on Cardiometabolic Profile and Neurodevelopment
Suspected preterm labour (SPL), define as the presence of regular and painful uterine contractions and cervical shortening, constitute a prenatal insult with potential long-term consequences.
- Trial name
- SKs (NCT05211297)
- Where
- Spain
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Mental Disorder
Improving Integration of Mentally Burdened Young Adults in the Labour Market
Young adults who do not successfully transition from compulsory education to upper secondary level are at increased risk of developing mental illness, as compared with their working peers.
- Trial name
- inklusiv (NCT03328286)
- Testing
- Weekly group meeting w/psychotherapist
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zurich University of Applied Sciences
Preterm Pregnancy, Preterm Birth
Prediction of the Onset of Term and Preterm Labour
This study will collect samples from pregnant women in order to identify biomarkers that relate to onset of spontaneous preterm labour.
- Conditions
- Preterm Pregnancy, Preterm Birth, Preterm Birth Complication, Preterm Premature Rupture of Membrane
- Trial name
- PREDICT (NCT04590677)
- Testing
- Samples required from group 1 (procedure within observational study), Samples required from group 2 (procedure within observational study)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Labor Analgesia
Anesthesia Clinical Practice During Labour Neuraxial Analgesia
The goal of this observational study is to evaluate the communication between the anesthesiologist and the patient prior the initiation and during the administration of the labor neuraxial analgesia.
- Trial name
- ACP-LNA (NCT07083167)
- Testing
- No Interventions.
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of British Columbia