Clinical trials: Lactate
Arterial Access, Peripheral Access
Correlation of Arterial and Venous Lactate and Base Deficit Values
The purpose of this study is to determine the correlation between pH, base deficit, and lactate values when comparing venous and arterial blood samples in the pediatric population.
- Conditions
- Arterial Access, Peripheral Access, Central Venous Catheter
- Trial name
- NCT02888431
- Testing
- bedside point-of-care device
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Joseph D. Tobias
Hygiene
Dermacyd Infantile - Acceptability.
Primary Objective: To prove the safety of the formulation in normal conditions of use.
- Trial name
- NCT00881270
- Testing
- LACTIC ACID(ND)
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sanofi
Neurodegenerative Diseases, Leukodystrophy
Home Exercise for Individuals With Neurodegenerative Disease
The primary goal of this study is to address the need for targeted therapeutic interventions for impairments that impact walking in related neurodegenerative diseases.
- Conditions
- Neurodegenerative Diseases, Leukodystrophy, Ataxia, LBSL
- Trial name
- NCT05443906
- Testing
- Home exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Septic Shock, Sepsis
The Effect of Early Norepinephrine on Stroke Volume Index, Cardiac Index, Lactate, and Arterial Elastance in Pediatric Septic Shock
The complexity of pediatric septic shock arise from its varied pathophysiology, which includes systemic inflammation, cardiovascular collapse, and multiple organ dysfunction.
- Trial name
- NCT06461390
- Testing
- Norepinephrine, Ringer's Lactate
- Where
- Indonesia
- Volunteers
- 42 people
- Sponsor
- Universitas Indonesia
Hygiene
Dermacyd PH_DETINLYN Sweet Flower (Lactic Acid) - Safety
To prove the safety of the gynaecological formulation in normal conditions of use.
- Trial name
- NCT00785148
- Testing
- Dermacyd PH_DETINLYN Sweet Flower (Lactic Acid)
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sanofi
Hypoglycaemia
Point of Care Ketone Measurement in the Newborn
Low blood sugar levels are common in babies after birth. This may be normal as babies can use other sources of energy. However if a baby does not produce these fuels the brain can be starved of energy and be damaged.
- Trial name
- POCKET (NCT02341313)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Kathryn Beardsall
Shock
PICU Admission Lactate and Central Venous Oxymetry Study
Observational multicentre cohort study. Children admitted to a Dutch PICU are studied for lactate levels and ScvO2. Children instrumented with arterial and central venous catheters are included within the first 12 hours after…
- Trial name
- PALVOS (NCT01696175)
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Radboud University Medical Center
Judo, Recovery of Function (G11.427.698.620)
Recovery Strategies and Diurnal Variation in Adolescent Judokas
The purpose of this study is to compare the effects of three different recovery strategies-sports massage (SM), static stretching (SS), and passive rest (PR)-on physiological and neuromuscular recovery in adolescent male judokas.
- Conditions
- Judo, Recovery of Function (G11.427.698.620), Athletic Performance, Muscle Fatigue
- Trial name
- RECOV-JUDO (NCT07586007)
- Testing
- Sports Massage, Static Stretching, Passive Rest
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Inonu University
Tobacco Smoke Pollution, Maternal Exposure During Pregnancy
Prenatal Tobacco Exposure and Newborn Outcomes: A Maternal Urinary Cotinine Study
Prenatal exposure to tobacco smoke, through either active maternal smoking or secondhand exposure, has been associated with impaired fetal oxygenation, metabolic stress, and adverse early neonatal outcomes.
- Conditions
- Tobacco Smoke Pollution, Maternal Exposure During Pregnancy, Infant, Newborn, Carbon Monoxide Poisoning
- Trial name
- NCT07201181
- Testing
- Maternal Urinary Cotinine Assessment
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Post-cardiac Surgery, Hyperlactatemia
Lactate Acidosis in Postoperative Hearts
This is a single-center, observational study. Investigators aim to characterize the metabolism of lactate in children over the first forty-eight hours following cardiac surgery. Blood samples will be obtained up to 12 timepoints.
- Trial name
- NCT03025659
- Testing
- Pyruvate levels
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Florida
Athletic Performance
High-Intensity Interval Training Effects on Fitness in Youth Soccer Players
This study aims to investigate the effects of an 8-week high-intensity interval training (HIIT) program on aerobic capacity, anaerobic power, blood lactate levels, and sprint performance in young male soccer players.
- Trial name
- NCT07757100
- Testing
- High-Intensity Interval Training (HIIT)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ercüment Erdoğan
Athletic Performance, Aerobic Capacity
Individualized Training to Improve Aerobic Capacity and 2,000 m Rowing Performance in Youth Rowers
The goal of this randomized clinical trial is to learn whether an individualized rowing training program based on ventilatory thresholds can improve aerobic capacity and 2,000 m rowing performance in youth rowers from Valdivia…
- Conditions
- Athletic Performance, Aerobic Capacity, Rowing Performance
- Trial name
- NCT07602244
- Testing
- Individualized Rowing Training, Usual Rowing Training
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universidad San Sebastián
Leukoencephalopathies, LBSL
Natural History Study of Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation (LBSL)
In this study, we will conduct retrospective chart and imaging reviews and prospective longitudinal virtual assessments of individuals with LBSL.
- Conditions
- Leukoencephalopathies, LBSL, Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation, White Matter Disease
- Trial name
- NCT03624374
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
HIV Infections
Vitamin B Therapy for Hyperlactatemia
The purpose of this study is to see if vitamin B can treat mild hyperlactatemia (a higher than normal level of lactate in the blood) in patients who take nucleoside reverse transcriptase inhibitors (NRTIs).
- Trial name
- NCT00031057
- Testing
- Thiamine hydrochloride, Riboflavin
- Where
- 3 sites in United States
- Volunteers
- 225 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Muscle Fatigue
Microcurrent Therapy and the Post-Exercise Physiological Response (MENS_PE)
The goal of this clinical trial is to find out whether microcurrent therapy changes blood levels of creatine kinase, a marker of muscle stress, during the first 48 hours after exercise in military personnel.
- Trial name
- MENS_PE (NCT07877337)
- Testing
- Microcurrents Therapy
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Sports Injury
Clinical Trial for Vespa Amino Acid Mixture (VAAM®)
ATP is generated mainly through anaerobic metabolism during strenuous exercise, which is then followed by the generation of lactic acid.
- Trial name
- NCT03121040
- Testing
- Vespa amino acid mixture
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Shanghai Meiji Health Science and Technology Co., Ltd.
LBSL, Leukoencephalopathies
Quantifying Disease Progression in LBSL
Leukoencephalopathy with brain stem involvement and lactate elevation (LBSL) is a genetic disorder caused by biallelic mutations in the DARS2 gene that encodes mitochondrial aspartyl tRNA synthase.(1, 2) It is characterized by…
- Trial name
- LBSL (NCT05750979)
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- M. Engelen
Antibiotic Side Effect
The Effect of Probiotic Supplement on Urinary D-lactic Acid Level in Newborns
It is thought that prophylactic enteral probiotics in newborns may play a role in the prevention of infection and NEC-related morbidity by preventing bacterial migration in the mucosa, reducing their number by competing with…
- Trial name
- NCT04620629
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people
- Sponsor
- H. Tolga Çelik
GLUT1 Deficiency Syndrome, GLUT1DS1
Sodium Lactate Infusion in GLUT1DS Patients
This study investigates the effect of lactate infusion on epileptic discharges on EEG and seizure frequency in glucose transporter 1 deficiency syndrome (GLUT1DS) patients.
- Conditions
- GLUT1 Deficiency Syndrome, GLUT1DS1, GLUT1DS2, Epilepsy
- Trial name
- NCT04112862
- Testing
- sodiumlactate
- Where
- Netherlands
- Volunteers
- 2 people
- Sponsor
- Radboud University Medical Center
Critical Illness, Enteral Feeding Intolerance
Evaluation of Enteral Nutrition in Critically Ill Children
The aim of this study was to evaluate the effect of calorie and enteral feeding timing on survival in critically ill children receiving inotropic, vasopressor and inodilatory supplements.
- Trial name
- NCT04013893
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Cukurova University