Clinical trials: Lactic Acid
Newborn Hypoxic-Ischemic Encephalopathy
Evaluation of a PCM Mattress to Treat HIE Infants During Transport
Background the research proposed herein is in line with the Swedish Research Council's current focus on International collaborations and postdoctoral work abroad.
- Trial name
- PCMhypo (NCT05361473)
- Testing
- The NeoHilda Point of care method, Traditional evaluation
- Where
- Vietnam
- Volunteers
- 140 people
- Sponsor
- Karolinska Institutet
Brain Tumor, Anesthesia
Lactate Levels Correlates With Ki-67 in Brain Tumor Surgery
In neurosurgery, brain tumor patients show increased levels of lactate at the beginning of surgery. This has been related to malignancy. Ki-67 is a cell proliferation index used as a marker of tumor mitotic activity.
- Trial name
- NCT03531307
- Testing
- Data correlation
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Ricard Valero
Acne Vulgaris
The Effectiveness and Safety of Cleanser Containing Triethyl Citrate, Pyruvic Acid, Combination Cream Containing Triethyl Citrate, Ethyl Linoleate, GT Peptide-10, Salicylic Acid 0,5%, Zinc Lactate, Hyaluronic Acid and Spot Cream Containing Triethyl Citrate, Ethyl Linoleate, GT Peptide-10, Honokiol
The goal of this clinical study is to learn the effectiveness and safety of Cleanser containing Triethyl citrate, Pyruvic acid, Combination cream containing Triethyl citrate, Ethyl linoleate, GT peptide-10, Salicylic acid 0,5%…
- Trial name
- NCT06775314
- Testing
- Cleanser, Combination cream, spot cream
- Where
- Indonesia
- Volunteers
- 102 people
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Hygiene
Dermacyd PH_DETINLYN Tangerine Mix (Lactic Acid) - Safety.
To prove the safety of the gynaecological formulation in normal conditions of use.
- Trial name
- NCT00785642
- Testing
- Dermacyd PH_DETINLYN Tangerine Mix (Lactic Acid)
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sanofi
Recurrent Tonsillitis in Children
A Phase I/II to Assess Safety, Tolerability and Efficacy of DL-lactic Acid Syrup in Children With Recurrent Tonsillitis
The study objectives are to evaluate Tonsitin™ (10% Lactic Acid) safety, tolerability and preliminary efficacy, as a potent treatment for Recurrent Tonsillitis in children.
- Trial name
- NCT01988558
- Testing
- DL - Lactic Acid, Raspberry flavored syrup
- Where
- 3 sites in Israel
- Volunteers
- 51 people
- Sponsor
- Yali Pharmaceuticals
Traumatic Brain Injury
Effect of Exogenous Lactate on Neurocognitive in Brain Trauma
Mild traumatic brain injury (TBI) is the most common type of brain injury. Post-mild TBI disability could stem from cognitive, physical, psychological and social dysfunction which resulted in significant disability and…
- Trial name
- NCT01455376
- Testing
- hyperosmolar sodium lactate
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Padjadjaran
The Precision Personal Timeline in Definitive Surgery Associated With Outcome
Timing of Damage Control Orthopedic Surgery
The decision to operate and surgical timing on multi-trauma patients remains controversial, inappropriate surgical timing may cause more complications which lead to poor prognosis.
- Trial name
- NCT05785143
- Testing
- Utilizing dry lab database to analyze the prognostic factors of multi-trauma patients and determine the optimal timing of definitive orthopedic operation
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- China Medical University Hospital
Leukoencephalopathies, LBSL
Natural History Study of Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation (LBSL)
In this study, we will conduct retrospective chart and imaging reviews and prospective longitudinal virtual assessments of individuals with LBSL.
- Conditions
- Leukoencephalopathies, LBSL, Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation, White Matter Disease
- Trial name
- NCT03624374
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Hygiene
Dermacyd PH_DETINBACK Tangerine Mix (Lactic Acid) - Safety.
The purpose of this study is to prove the safety in normal conditions of useof the product Dermacyd PH_DETINBACK Tangerine Mix (Lactic Acid).
- Trial name
- NCT00783939
- Testing
- Lactic Acid
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sanofi
Normal Anion Gap Metabolic Acidosis
Ringer's Lactate Versus Normal Saline in Caesarean Section
The objective of this study is to compare the effect on mean maternal and neonatal pH, and 24-hour postoperative morbidity, following intraoperative infusion of Ringer's Lactated versus normal saline in caesarean section at…
- Trial name
- NCT01585740
- Testing
- 0.9% Normal Saline, Ringer's Lactate
- Where
- Uganda
- Volunteers
- 500 people
- Sponsor
- Makerere University
Mitochondrial Disorders, Mitochondrial Genetic Disorders
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
- Conditions
- Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes
- Trial name
- NAMDC (NCT01694940)
- Where
- 17 sites in United States, Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Athletic Performance, Aerobic Capacity
Individualized Training to Improve Aerobic Capacity and 2,000 m Rowing Performance in Youth Rowers
The goal of this randomized clinical trial is to learn whether an individualized rowing training program based on ventilatory thresholds can improve aerobic capacity and 2,000 m rowing performance in youth rowers from Valdivia…
- Conditions
- Athletic Performance, Aerobic Capacity, Rowing Performance
- Trial name
- NCT07602244
- Testing
- Individualized Rowing Training, Usual Rowing Training
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universidad San Sebastián
Hygiene
Dermacyd PH_DETINBACK (Lactic Acid) Sweet Flower - Safety.
To prove the safety in normal conditions of use.
- Trial name
- NCT00785850
- Testing
- Dermacyd PH_DETINBACK (Lactic Acid) Sweet Flower
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sanofi
Hygiene
Dermacyd Infantile - Acceptability.
Primary Objective: To prove the safety of the formulation in normal conditions of use.
- Trial name
- NCT00881270
- Testing
- LACTIC ACID(ND)
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sanofi
Metabolic Ketoacidosis, Ketoacidemia
0.9% Saline Versus Balanced Solutions in Severe Diabetic Ketoacidosis
Severe diabetic ketoacidosis (DKA) is a potentially serious complication of diabetes mellitus. The treatment regimen is based on insulin and rehydration. The choice of rehydration solution is a question that remains open.
- Conditions
- Metabolic Ketoacidosis, Ketoacidemia, Acetonemia, Acetonuria
- Trial name
- NCT05808972
- Testing
- Sodium chloride 0.9% (SC), Ringer lactate (RL)
- Where
- Tunisia
- Volunteers
- 92 people
- Sponsor
- Tunis University
Hyponatremia
Comparison of Ringer Lactate and Isotonic Acetate Solution as Perioperative Maintenance Fluid for Children
In children fluids are supplemented during surgery to provide volume, to maintain blood glucose levels, electrolyte balance and to meet the ongoing fluid losses during surgery.
- Trial name
- NCT02936167
- Testing
- Ringer Lactate, Plasmalyte
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Lactic Acidosis
Phase II Pilot Randomized Study of Sodium Dichloroacetate in Patients With Congenital Lactic Acidemia
OBJECTIVES: I. Determine the pharmacokinetics of sodium dichloroacetate (DCA) in patients with congenital lactic acidemia. II. Determine the efficacy of DCA in decreasing the frequency and/or severity of acute episodes of…
- Trial name
- NCT00004493
- Testing
- sodium dichloroacetate
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, San Diego
Blood Flow Restriction Training, Muscle Oxygenation
"How Blood Flow Restriction Exercise Affects Muscle Oxygenation and Lactate in Elite Athletes"
This study investigates the effects of blood flow restriction (BFR) training combined with low-intensity aerobic exercise on muscle oxygenation, total hemoglobin (THb), and blood lactate levels in elite athletes, comparing them…
- Conditions
- Blood Flow Restriction Training, Muscle Oxygenation, Physiological Adaptations
- Trial name
- NCT06918314
- Testing
- Blood Flow Restriction Kaatsu Training Device
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Sepsis
Validation of Early Warning Score & Lactate in Prehospital Screening
Sepsis claims over 37,000 lives in the United Kingdom each year- more than lung cancer, and more than breast cancer, bowel cancer and HIV/AIDS combined. Less than two-thirds of patients who develop sepsis will survive.
- Trial name
- VELPS (NCT02189096)
- Testing
- NEWS and Sepsis Screening, Point of care lactate measurement
- Volunteers
- 705 people
- Sponsor
- University of the West of Scotland
Leukodystrophy, White Matter Disease
LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies
Leukodystrophies, and other heritable disorders of the white matter of the brain, were previously resistant to genetic characterization, largely due to the extreme genetic heterogeneity of molecular causes.
- Conditions
- Leukodystrophy, White Matter Disease, 4H Syndrome, Adrenoleukodystrophy
- Trial name
- NCT02699190
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Children's Hospital of Philadelphia