Clinical trials: Language
Developmental Disability
Communication Outcomes for South African Children With Developmental Disabilities
The goal is to remediate speech and language disorders early in the lives of South African children with significant developmental disorders (DD) by enhancing the health care service delivery system to better serve families…
- Trial name
- NCT03409406
- Testing
- Caregiver Intervention, ST Intervention
- Where
- South Africa
- Volunteers
- 100 people
- Sponsor
- Georgia State University
High-risk Pregnancy, Hospitalization
LLM-Generated Medical Summaries During Hospitalization to Improve Patient Activation in High-Risk Pregnancies
The goal of this clinical trial is to learn if AI-generated medical summaries help hospitalized pregnant participants better understand and actively participate in their own care.
- Conditions
- High-risk Pregnancy, Hospitalization, Patient Activation, Artificial Intelligence (AI)
- Trial name
- NCT07823517
- Testing
- LLM-Generated Medical Summaries
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Cerebral Infarction
Early Determinants of Multidimensional Outcome at School Age After Neonatal Arterial Ischemic Stroke
While perinatal ischemic stroke is the most frequent form of childhood stroke, early determinants of outcome remain poorly understood.
- Trial name
- NCT02511249
- Where
- 5 sites in France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
MONITOR, COACH
Promoting Early Intervention Timing and Attention to Language
The proposed study (PETAL: Promoting Early intervention Timing and Attention to Language) aims to determine the timing of intervention among infants with Increased Likelihood for Autism (ILA; at risk for autism by virtue of…
- Trial name
- PETAL (NCT05853861)
- Testing
- JASPER Babble
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- University of California, Los Angeles
Stuttering in Adolescence, Bullying of Child
The Classroom Communication Resource (CCR) Intervention to Change Grade 7 Peer's Attitudes Towards Children Who Stutter (CWS)
Children who stutter (CWS) are at high risk of being teased and bullied in primary school because of the negative peer attitudes and perceptions towards stuttering.
- Trial name
- CCR (NCT03111524)
- Testing
- Classroom Communication Resource, No intervention
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Rizwana Mallick
Language Development
Single Case Research Design: Deaf Children's Language Outcomes
Eight deaf children in kindergarten to 3rd grade classes will be randomly selected for single case research. Their language skills will be monitored and assessed daily.
- Trial name
- NCT06722261
- Testing
- Strategic and Interactive Signing Instruction
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- The University of Tennessee, Knoxville
Language Development
Evaluating the Effectiveness of the Reader Organisation's Get Into Reading Intervention
The investigators will evaluate the effectiveness of a parent-child shared reading intervention run by The Reader Organisation. The investigators will be asking parents and children across Liverpool to either (i) attend a weekly…
- Trial name
- NCT02659579
- Testing
- The Reader Organisation's Shared Reading Programme, Shared Reading control
- Where
- United Kingdom
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Caroline Rowland
DLD
Effect of Phonotactic Probability and Orthography on Vocabulary Learning
The purpose of the study is to investigate how phonotactic probability) and orthography affect vocabulary by children with low oral language levels.
- Trial name
- VOCAB+ (NCT06935851)
- Testing
- VOCAB +
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Simulation Training
Effectiveness of Two Simulation-Based Functional Nasopharyngoscopic Velopharyngeal Assessment Trainings
The aim of this clinical trial was to compare the effectiveness of functional nasopharyngoscopic velopharyngeal assessment training given to undergraduate speech and language therapy students on a 3D printed endoscopy training…
- Trial name
- NCT05732376
- Testing
- Nasopharyngoscopic Velopharyngeal Training with 3D Printed Endoscopy Training Model, Nasopharyngoscopic Velopharyngeal Training with Ready-Made Endoscopy Training Model
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Medipol University
Language Disorder, Healthy
Language Stimuli Screening in Children
This study will determine baseline language skills in children 4 to 8 years old. The data will be used to design studies using functional magnetic resonance imaging (fMRI) to identify what areas of the brain in children are…
- Trial name
- NCT00016796
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Pulp and Periapical Tissue Disease
Comparative Analysis of Diagnostic Accuracy and Case Difficulty Assessment of Three Large Language Models
This prospective, blinded diagnostic accuracy study aims to compare the performance of three large language models-ChatGPT (GPT-5.5 Pro), Gemini 3.1 Pro, and Claude Opus 4.7-in endodontic diagnosis and case difficulty assessment.
- Trial name
- NCT07732985
- Testing
- ChatGPT (GPT-5.5 Pro), Gemini 3.1 Pro, Claude Opus 4.7
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- Cairo University
Developmental Language Disorder (DLD)
Evaluating the Effect of Combined Parent Training Plus Speech Therapy on Children With Speech Development Disorder.
Language is an extremely complex cognitive function that, in situations of typical development, i.e. in the absence of deficits or environmental risk, is generally acquired with apparent ease and naturalness (Kuhl, 2010).
- Trial name
- DLD25!! (NCT07426276)
- Testing
- Assisted speech therapy intervention + parent training, standard speech therapy
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Language Development
Supporting Children's School Readiness.
The aim of this project is to test whether training parents to ask their children 'inference- eliciting' questions during book reading is effective in promoting story comprehension for 4-year-olds from a range of socio-economic…
- Trial name
- NCT02854462
- Testing
- Language comprehension intervention, Counting intervention
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Literacy, Literacy-language Intervention
Haptics in Virtual Reality
The purpose of this study is to investigate the role of non-invasive wearable haptic feedback, in supporting literacy-focused Virtual Reality (VR) learning environments.
- Conditions
- Literacy, Literacy-language Intervention, Haptics
- Trial name
- NCT07209228
- Testing
- Haptic-Integrated Interactive Virtual Reality Experience, Traditional Virtual Reality Experience (Hand Controllers)
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Miami
Autism, Mental Retardation
MR Scanning of Very Young Children With Severe Developmental Disorders
The specific is to study the MR morphologic and spectroscopic brain correlates and predictors of development in children with severe developmental disorders (autistic spectrum disorders and/or mental retardation and/or language…
- Conditions
- Autism, Mental Retardation, Language Disorder
- Trial name
- NCT00156221
- Where
- Netherlands
- Sponsor
- UMC Utrecht
Diagnosis
The Impact of Large Language Models on Diagnostic Reasoning Among LLM-Trained Medical Doctors
This study aims to evaluate whether large language model-trained medical doctors demonstrate enhanced diagnostic reasoning performance when utilizing ChatGPT-4o alongside conventional resources compared to using conventional…
- Trial name
- NCT06774612
- Testing
- ChatGPT-4o
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lahore University of Management Sciences
Acute Respiratory Distress Syndrome, Pneumonia in Children
AI-Guided Mechanical Ventilation in Children: A Randomized Controlled Trial
This prospective, randomized controlled trial aims to evaluate whether an AI-driven decision support system can improve clinical outcomes for mechanically ventilated pediatric patients (aged 1 month to 18 years) in the PICU…
- Conditions
- Acute Respiratory Distress Syndrome, Pneumonia in Children, Respiratory Failure (Pediatric Patients), Congenital Heart Disease in Children
- Trial name
- NCT07728136
- Testing
- AI-generated recommendations for ventilator parameters.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wu Rongzhou
Hearing Loss, Language Development
Improving Outcomes Using Technology for Children Who Are DHH
This study evaluates the efficacy of using augmentative and alternative communication (AAC) technology for enhancing language development in children who are deaf or hard of hearing.
- Conditions
- Hearing Loss, Language Development, Social Behavior
- Trial name
- NCT02998164
- Testing
- augmentative and alternative communication technology, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 154 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Selective Mutism
Evaluating Intensive Group Behavioral Treatment for Children With Selective Mutism
This goal of this study is to evaluate an intensive group behavioral treatment (IGBT) program for children with selective mutism, a low base-rate childhood anxiety disorder.
- Trial name
- NCT03612102
- Testing
- Intensive Group Behavioral Treatment (IGBT)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Florida International University
Condition 1. Children With ALL Are Still Alive and the Age of 18 Years of Age., Condition 2. Has Been Completed to Guide the Treatment Regimen Were in Remission.
The Related Factors With Resilience in Caregivers Whose Child With Leukemia
The purpose of this study was to explore caregivers stress, family functioning, social support and family resilience of families whose children had acute lymphoblastic leukemia.
- Conditions
- Condition 1. Children With ALL Are Still Alive and the Age of 18 Years of Age., Condition 2. Has Been Completed to Guide the Treatment Regimen Were in Remission., Condition 3. Caregiver Can or Taiwanese Language Communicator.
- Trial name
- NCT01249781
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- China Medical University Hospital