Clinical trials: Language Development
Language Development Disorders, Speech Sound Disorder
Manipulating Linguistic Complexity to Improve Child Language Treatment Outcomes
Phonological disorder (PD) and specific language impairment (SLI) directly impact a child's ability to communicate and are among the most prevalent developmental disorders.
- Trial name
- NCT03977701
- Testing
- Phonological treatment, Morpheme treatment
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- San Diego State University
Developmental Language Disorder, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder During Book Reading
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT06026124
- Testing
- Retrieval-based word learning: Repeated Spaced Retrieval condition, Retrieval-based word learning: Repeated Study condition
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Purdue University
Language Delay, Language Development Disorders
Vocabulary Intervention for Late Talkers
Most studies regarding word learning have focused on understanding when and how infants learn words. At 24 months, typically developing infants know between 200 and 300 words and add new words to their vocabularies at a rapid…
- Trial name
- NCT03379818
- Testing
- Shape training intervention, Specific word training
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Birmingham
Language Development
STEM (Science, Technology, Engineering & Math) Familia Talk
After development of the Talk Stem Familia (TSF) smart-speaker application prototype, the study will evaluate the prototype's efficacy in a within-subjects pre-post design study.
- Trial name
- NCT03766906
- Testing
- Talk STEM Familia app
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Developmental Language Disorder
Maximizing Outcomes for Preschoolers With Developmental Language Disorders
The objective of the proposed study is to evaluate the efficacy of the Enhanced Milieu Teaching-Sentence Focus (EMT-SF) intervention, implemented by caregivers and interventionists, relative to a control condition enrolling 108…
- Trial name
- NCT03782493
- Testing
- the Enhanced Milieu Teaching-Sentence Focus
- Where
- 2 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Specific Language Impairment
Accelerating Word Learning in Children With Language Impairment
This research attempts to adapt and optimize a word learning treatment, specifically interactive book reading, for use with Kindergarten children with Specific Language Impairment (SLI).
- Trial name
- NCT01829360
- Testing
- Treatment (interactive book reading, dialogic reading, shared book reading)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Kansas
Autism Spectrum Disorder, Apraxia of Speech
Video Assisted Speech Technology to Enhance Motor Planning for Speech
Nearly 3.5 million Americans are diagnosed with Autistic Spectrum Disorder (ASD), a communication disorder that causes skill limitations in the areas of language acquisition, sensory integration, and behavior.
- Trial name
- VAST (NCT04764539)
- Testing
- Video Assisted Speech Therapy (VAST)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- iTherapy, LLC
Fragile X Syndrome
AFQ056 for Language Learning in Children With FXS
The purpose of this clinical trial is to investigate the impact of AFQ056 on language learning in 3-6 year old children with Fragile X Syndrome (FXS).
- Trial name
- FX-LEARN (NCT02920892)
- Testing
- AFQ056, Language Intervention
- Where
- 14 sites in United States
- Volunteers
- 110 people
- Sponsor
- Elizabeth Berry-Kravis
Dyslexia, Developmental
Neural Mechanisms of Successful Intervention in Children With Dyslexia
Dyslexia, an impairment in accurate or fluent word recognition, is the most common learning disability affecting roughly ten percent of children.
- Trial name
- NCT04323488
- Testing
- Lindamood-Bell Seeing Stars
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autistic Disorder, Autism
Mental Imagery Therapy for Autism (MITA) - an Early Intervention Computerized Language Training Program for Children With ASD
Mental Imagery Therapy for Autism (MITA) is a unique, early-intervention application for children with Autism Spectrum Disorder (ASD).
- Conditions
- Autistic Disorder, Autism, ASD
- Trial name
- NCT02708290
- Testing
- MITA Prefrontal Synthesis exercises - each activity adapts to deliver the exercise that is at the exact level of difficulty appropriate for a child at any given point in time
- Where
- United States
- Volunteers
- 6,454 people
- Sponsor
- ImagiRation, LLC
Language Development, Literacy
Digital Literacy Promotion
This study evaluates the effects of digital versus standard literacy promotion, as well as dialogic language behaviors and reading comprehension among infants when comparing the use of e-books to standard board books.
- Trial name
- DLP (NCT03121365)
- Testing
- Digital/E-Book Arm, Standard/Board Book Arm
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Language Development Disorders
Kindergarten Children Acquiring Words Through Storybook Reading
Children with Specific Language Impairment (SLI) are slower to learn new words than their peers, placing them at risk for academic failure.
- Trial name
- KAWStory (NCT03586479)
- Testing
- Interactive storybook reading
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Kansas
Autism
Autologous Cord Blood Stem Cells for Autism
Evaluate the efficacy of one infusion of stem cells from autologous umbilical cord blood in patients with autism over six months after infusion as measured by changes in expressive and receptive language.
- Trial name
- NCT01638819
- Testing
- Autologous Cord Blood Stem Cells
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Sutter Health
Developmental Language Disorder, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder: Verb Learning
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT06001866
- Testing
- Retrieval-based verb learning: Repeated Spaced Retrieval condition, Retrieval-based verb learning: Repeated Study condition
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Purdue University
Autism Spectrum Disorders
A Trial of the Drug Donepezil for Sleep Enhancement and Behavioral Change in Children With Autism
Background: Some children with autism spectrum disorders (ASD) do not have normal sleep cycles. Some of these children spend very little time in the rapid eye movement (REM) stage of sleep.
- Trial name
- NCT01887132
- Testing
- Donepezil
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Mental Health (NIMH)
Language Developmental Disorders
Working on Rapid Language Development in Toddlers
The goal of the study is to examine the effects of teaching parents to use language support strategies on language skills in toddlers with language delays.
- Trial name
- WORLD (NCT01975922)
- Testing
- Enhanced Milieu Teaching
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Developmental Language Disorder, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT05325333
- Testing
- Retrieval-based word learning: Expanding retrieval practice schedule, Retrieval-based word learning: Standard retrieval practice schedule
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Purdue University
Developmental Language Disorder and Language Impairment, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder During Book Reading II
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder and Language Impairment, Specific Language Impairment, Language Development
- Trial name
- NCT07048392
- Testing
- Retrieval-based word learning: Repeated Spaced Retrieval condition, Retrieval-based word learning: Repeated Study condition
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Purdue University
Obesity, Infant, Language Development
Music and Child Health and Development
The goal of this clinical trial is to learn about the effects of a music enrichment program on the quality of parent child interactions, a child's motivation to eat, and a child's language environment in 9 to 24 month-old…
- Conditions
- Obesity, Infant, Language Development, Parent-Child Relations
- Trial name
- NCT05868811
- Testing
- Music Together, Play Group
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Developmental Language Disorder, Specific Language Impairment
Retrieval-based Word Learning in Developmental Language Disorder: Adaptive Retrieval Schedule
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT06995014
- Testing
- Retrieval-based word learning: Standard retrieval practice schedule, Retrieval-based word learning: Adaptive retrieval practice schedule
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Purdue University