Clinical trials: Language Disorder
Neurofibromatosis Type 1, Reading Disabilities
Neurobiology and Treatment of Reading Disability in NF-1
The goal of this trial is to determine if children with neurofibromatosis type 1 who have reading disabilities respond the same way-both behaviorally and neurobiologically-to specialized treatment programs as children with…
- Trial name
- NCT00624234
- Testing
- Tutoring Program I, Tutoring Program II
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Developmental Language Disorder and Language Impairment, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder During Book Reading II
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder and Language Impairment, Specific Language Impairment, Language Development
- Trial name
- NCT07048392
- Testing
- Retrieval-based word learning: Repeated Spaced Retrieval condition, Retrieval-based word learning: Repeated Study condition
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Purdue University
Cerebral Palsy (CP), Dysarthria
Speech and Arm Combined Exergame
The purpose of this study is to develop innovative home therapy games to train the weak arm and improve speech intelligibility (clarity) of children with hemiplegia from cerebral palsy.
- Trial name
- SPACE (NCT06817941)
- Testing
- Speech only, Hand/Arm only, Speech and arm combined
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Rutgers, The State University of New Jersey
Stuttering, Childhood, Stuttering
Network Connectivity and Temporal Processing in Adolescents Who Stutter
The specific purpose of this clinical trial is to compare performance on rhythm perception and production tasks between children who stutter and children who do not stutter.
- Trial name
- NCT05286151
- Testing
- Rhythm discrimination
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Dysarthria, Down Syndrome
Intensive Dysarthria Sessions in Adults and Children With Down Syndrome
This research study is designed to investigate the feasibility and treatment effects of a behavioral speech treatment in adults and children with Down Syndrome (DS) and dysarthria.
- Trial name
- NCT01684670
- Testing
- Speech sessions
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Autism Spectrum Disorder, Asperger Syndrome
Effects of a Multimodal Exercise Program for Children With ASD
Exploring the effects of an exercise program for children ages 6 -26 years old who have been diagnosed with autism spectrum disorder and neurotypical children respond to high-intensity whole body exercise interventions (Group 1)…
- Trial name
- NCT05509231
- Testing
- High-intensity exercise, Wearable glove and arm sleeve device to measure movement
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Developmental Dyslexia
Orthophonic and / or Proprioceptive Treatment of Developmental Dyslexia.
To show the interest of the association of proprioceptive and orthophonic care of dyslexic children. The assumption is that proprioceptive support by correcting a centrally located spatial localization instability restores the…
- Trial name
- Pro-Pho-Dys (NCT03448237)
- Testing
- Speech Therapy, Proprioceptive treatment
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Scalab CNRS 9193
Down Syndrome
Functional Communicative Profile of Children With Down Syndrome
The aim of this study was to verify the use of communicative functions by children with DS in two interaction conditions: interaction with therapist and interaction with parent.
- Trial name
- NCT00844259
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
ASD
Mental Imagery Therapy for Autism (MITA) - an Early Intervention Computerized Language Training Program for Children With Autism
Mental Imagery Therapy for Autism (MITA) is a highly innovative adaptive language therapy application for children with autism. MITA exercises are limitless in variations, therefore avoiding routinization.
- Trial name
- MITA-RCT (NCT07326423)
- Testing
- Mental Imagery Therapy for Autism (MITA), General executive function
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- ImagiRation, LLC
Language Development Disorders
Memorisation of Phonologic Information Among Children With Oral Language Developement Disorder
The disorder of oral language development is defined by the delay in language acquisition in children who possess efficient auditory acuity and normal non verbal intellect.
- Trial name
- MEMENTO (NCT02609542)
- Testing
- Eye Tracking
- Where
- France
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Dyslexia
Static and Dynamic Balance in Children With Dyslexia
Dyslexia is described as a learning disability with a neurological origin. It is a widespread disease, characterized by difficulties in recognition of words, spelling, and decoding.
- Trial name
- NCT04386161
- Testing
- Scheduled exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Marmara University
Infratentorial Neoplasms, Mutism
Cerebellar Mutism Syndrome Study
The purpose of this study is to determine why up to 25% of the pediatric patients who have surgery for a tumor in the posterior fossa develops the Cerebellar Mutism Syndrome (CMS).
- Trial name
- NCT02300766
- Where
- 32 sites in Austria, Belgium and 12 more
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Auditory Perceptual Disorder, Language Delay
Hereditary Deficits in Auditory Processing Leading to Language Impairment
Some children with certain language disorders may not properly process the sounds they hear, resulting in language impairments. The purpose of this study is to determine if deficits in auditory temporal processing the way the…
- Conditions
- Auditory Perceptual Disorder, Language Delay, Language Disorder
- Trial name
- NCT00004570
- Where
- United States
- Volunteers
- 875 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Down Syndrome
How Simplified Language Affects Comprehension and Learning in Young Children With Down Syndrome
The long-term study goal is to experimentally evaluate the components (and likely active ingredients) of early language interventions for young children with Down syndrome (DS).
- Trial name
- NCT06951516
- Testing
- Linguistic simplification
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Michigan State University
Internal Rotation Contracture-shoulder, Articulation Disorders
Internal Rotation Deficit of the Glenohumeral Joint in Advanced-level Handball Players
The main objective of this study is to estimate the incidence and prevalence of Internal Rotation Deficit (IRD) defined by a measure of IRD 2 (Internal Rotation Deficit in position 2) strictly greater than 20 ° in a population of…
- Conditions
- Internal Rotation Contracture-shoulder, Articulation Disorders, Athletic Injuries
- Trial name
- GIRDH (NCT02011243)
- Where
- France
- Volunteers
- 86 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Autism Spectrum Disorder
Leucovorin for the Treatment of Language Impairment in Children With Autism Spectrum Disorder
The purpose of this study is to determine the effectiveness of folinic acid in the treatment of language problems in children with autism spectrum disorder. Folinic acid, also known as leucovorin, is approved by the U.S.
- Trial name
- NCT02839915
- Testing
- Folinic Acid
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Southwest Autism Research & Resource Center
Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders
Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.
The purpose of this study is to test how the delivery of Cognitive Behavioral Therapy (CBT) for pediatric anxiety and OCD via different methods might increase its availability and effectiveness.
- Conditions
- Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders, Anxiety Disorder, Anxiety
- Trial name
- IMPACT-RI (NCT06934525)
- Testing
- Team-delivered, exposure-based CBT
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Bradley Hospital
Developmental Language Disorder, Reading; Difficult
Promoting Caregiver Implementation of an Effective Early Learning Intervention
The goal of this study is to examine the impact of a caregiver-implemented shared reading program, Sit Together and Read (STAR), on children ages 4 to 5 with developmental language disorder.
- Trial name
- NCT06275815
- Testing
- Sit Together and Read (STAR), Monetary Reward, Text Encouragement
- Where
- 2 sites in United States
- Volunteers
- 320 people
- Sponsor
- Ohio State University
Diagnosis
Physician Reasoning on Diagnostic Cases With Large Language Models
This study will evaluate the effect of providing access to GPT-4, a large language model, compared to traditional diagnostic decision support tools on performance on case-based diagnostic reasoning tasks.
- Trial name
- NCT06157944
- Testing
- GPT-4
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stanford University
Developmental Language Disorder
Maximizing Outcomes for Preschoolers With Developmental Language Disorders
The objective of the proposed study is to evaluate the efficacy of the Enhanced Milieu Teaching-Sentence Focus (EMT-SF) intervention, implemented by caregivers and interventionists, relative to a control condition enrolling 108…
- Trial name
- NCT03782493
- Testing
- the Enhanced Milieu Teaching-Sentence Focus
- Where
- 2 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Northwestern University