Clinical trials: Language Disorder
Developmental Language Disorder
Sentence Prediction in Developmental Language Disorder
Millions of children - 7-12% of the school-age population - have developmental language disorder (DLD), a disorder that affects language learning, comprehension, and use.
- Trial name
- NCT07510854
- Testing
- Thematic role, Sentence complexity
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Aphasia, Cerebrovascular Accident
Role of the Right Brain in Recovery of Language Function in Chronic Stroke
This study will examine in healthy individuals and in patients with aphasia (a language disturbance that is usually caused by stroke, brain disease, or injury) which parts of the brain are involved in naming everyday objects.
- Trial name
- NCT00076479
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
HCM - Hypertrophic Cardiomyopathy
Automated Reports Generation of Cardiovascular Magnetic Resonance Imaging
The goal of this observational study is to evaluate the accuracy, completeness, and clinical consistency of large language model-generated cardiac magnetic resonance (CMR) imaging reports compared with expert radiologist reports…
- Trial name
- NCT07340762
- Testing
- large lanuage model
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Neurocognitive Dysfunction, Language Development
Can Singing Kangaroo Improve Outcome of Preterm Infants
To assess whether a musical intervention (maternal/paternal singing) during the skin-to-skin sessions (Kangaroo care) would improve the language development of the preterm infant.
- Trial name
- SingKang (NCT03795454)
- Testing
- Singing
- Volunteers
- 140 people
- Sponsor
- University of Helsinki
Autistic Disorder
Social Skills in Children With ASD and Process Drama
This is a one-group, pre-post feasibility study of an intensive, interdisciplinary (theatre, Occupational Therapy (OT), and Speech Language Pathology (SLP)) intervention targeted at social skill development in children, aged 3-4.
- Trial name
- NCT02850666
- Testing
- Interdisciplinary process drama
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Utah
Autism Spectrum Disorder, Asperger Syndrome
Effects of a Multimodal Exercise Program for Children With ASD
Exploring the effects of an exercise program for children ages 6 -26 years old who have been diagnosed with autism spectrum disorder and neurotypical children respond to high-intensity whole body exercise interventions (Group 1)…
- Trial name
- NCT05509231
- Testing
- High-intensity exercise, Wearable glove and arm sleeve device to measure movement
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Down Syndrome
Effects of Infant Massage on Development of Down Syndrome Babies
The aim of ths study is to know the effects of infant massage in the maturation of the baby with Down syndrome. Scale Psychomotor Development Early Childhood Brunet-Lézine-Revised will be used to measure the maturational…
- Trial name
- NCT03084497
- Testing
- Infant Massage
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- University of Seville
Posterior Fossa Mutism
Posterior Fossa Mutism on Quality of Life
Posterior fossa mutism (PFM) occurs in up to 30% of patients after resection of a posterior fossa tumor, most commonly a medulloblastoma.
- Trial name
- NCT02048176
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Autism Spectrum Disorder, Complication of Prematurity
Correlation of CXCR4 Expression in Premature Infants With a Diagnosis of Autism at 24 Months
Preterm children are at increased risk for autism spectrum disorders, with an estimated rate of 10%. In the US, about 1 in 8 pregnancies ends with a premature birth.
- Trial name
- ASD-CXCR4 (NCT01686685)
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Speech and Language Therapy
Parent-based Intervention for Language Delayed 2 to 3 Year Olds
The aim of the study is to evaluate the impact of parent based intervention on the language of 2 to 3 year old children from socially disadvantaged populations with a clinical diagnosis of primary language delay.
- Trial name
- NCT03083236
- Testing
- Standard PBI, Enhanced
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Solent NHS Trust
Developmental Language Disorder, Language Impairment
The Relationship Between Child Language Proficiency and Language of Treatment on the Outcomes of Bilingual Children with Developmental Language Disorder
Of the 12 million children in the USA growing up bilingual, about 1 million experience Developmental Language Disorder (DLD), a disorder in language learning and use.
- Trial name
- NCT06085300
- Testing
- Sentence recast
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Houston
Neurofibromatosis Type 1
Functional Imaging and Reading Deficit in Children With NF1
A monocenter pilot study on the acceptability and feasibility of a functional MRI protocol in children with NF1 with or without reading disabilities.
- Trial name
- NCT02422732
- Testing
- Neuropsychological assessments, morphological and functional MRI (fMRI), genetic analysis
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Toulouse
Non Fluent Aphasia in Subacute Stroke
Dual Hemisphere rTMS for Rehabilitation of Post Stroke Aphasia
To investigate the therapeutic effect of dual hemisphere repetitive transcranial magnetic stimulation (rTMS) on post-stroke non fluent aphasia.
- Trial name
- NCT01850836
- Testing
- repetitive transcranial magnetic stimulation
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Assiut University
Delirium
Validation Study of the "CORNELL ASSESSMENT PEDIATRIC DELIRIUM" (CAPD)" Scale in Italian Language
70 children (based on the inclusion and exclusion criteria described above) admitted in PICU will be daily assessed by two nurses (inter-evaluator agreement) using the Italian version of CAPD scale administered twice at a…
- Trial name
- NCT04589767
- Testing
- CAPD scale
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Azienda Ospedaliera di Padova
Benign Childhood Epilepsy With Centro-Temporal Spikes
Imaging the Effect of Centrotemporal Spikes and Seizures on Language in Children
This project examines how seizures, and abnormal brain activity, affect language skill in children with Benign Childhood Epilepsy with Centro-Temporal Spikes (BECTS).
- Trial name
- FIRST (NCT01521130)
- Testing
- Levetiracetam
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Slow Language Impairment
Better Understanding Slow Language Impairment
This study was designed to examine the development of children aged 6 to 10 with slow language impairment (SLI). The aim was threefold: (1) to investigate language skills of children with SLI at different levels - formal…
- Trial name
- SLI:COGGEN (NCT03660995)
- Testing
- Evaluation of language skills and procedural learning of children with SLI and their controls. DNA sampling.
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Hearing Impaired Children
Inter Disciplinary Approach to Vocabulary Development in Hearing Impairment
The research aims to address to address the role of interdisciplinary working between professionals in the field of speech and language pathology/therapy.
- Trial name
- NCT04962828
- Testing
- Vocabulary based intervention- Non Collaborative, Vocabulary based intervention - Collaborative
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Stuttering, Childhood
Comparative Study Between Three Different Methods for Stuttering Therapy in Children
The aim of work is comparing between three different methods for treatment of stuttering in children in order to reach to the best method for treatment
- Trial name
- NCT05291572
- Testing
- speech therapy only, hyperbaric oxygen therapy, medical treatment
- Volunteers
- 30 people
- Sponsor
- Sohag University
Developmental Language Disorder
Training Inner Speech in Children With Developmental Language Disorder
The complex and unclear relationship between language and executive function (EF) creates barriers to developing effective interventions for children with developmental language disorder (DLD) whose language difficulties often…
- Trial name
- NCT06880731
- Testing
- Modeling with Verbal Mediation, Modeling Only
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Dyslexia
VAlidation of an Educational Technological Tool for Dyslexic Adolescents: an Open Controlled Study
Virtual reality (VR) and augmented reality (AR) are gaining importance in the rehabilitation programs for learning disabilities.
- Trial name
- FORDYS (NCT05028647)
- Testing
- Virtual reality training, Augmented reality training
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Eugenio Medea