Clinical trials: Laparoscopic Appendectomy
Appendicitis Acute
Transumbilical Laparoscopy-assisted Appendectomy
transumbilical laparoscopic-assisted appendectomy (TULAA) was reported that the operation time was shorter and the postoperative frequency of complications was not high compared to conventional laparoscopic appendectomy (CLA)…
- Trial name
- NCT04485247
- Testing
- Transumbilical Laparoscopic-Assisted Appendectomy, 3-port laparoscopic appendectomy
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Myongji Hospital
Acute Appendicitis
Laparoscopic Appendectomy by Multi-port vs Single Port.
Laparoscopic appendectomy (LA) is nowadays considered the gold standard in fertile women affected by uncomplicated appendicitis. The level of evidence for benefits from LA in this subgroup is high.
- Trial name
- AMUSING (NCT01720082)
- Testing
- Single incision laparoscopic appendectomy, Multiport laparoscopic appendectomy
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Associazione Chirurghi Ospedalieri Italiani
Transcutaneous Electrical Acupoint Stimulation
Effects of TEAS on Postoperative Recovery of Intestinal Function in Children Undergoing Laparoscopic Appendectomy
With the development of surgical techniques, laparoscopic appendectomy has become a standard therapeutic procedure for acute appendicitis in many hospitals in recent years, which is considered as an effective and safe treatment…
- Trial name
- NCT05379660
- Testing
- transcutaneous electrical acupoint stimulation
- Volunteers
- 200 people
- Sponsor
- Xian Children's Hospital
Appendicitis
Comparative Study of Harmonic Scalpel vs. Suture Ligation for Appendix Base During Laparoscopic Appendectomy
This study is a comparative study between use of suture ligation vs harmonic scalpel for sealing and cutting the base of appendix.
- Trial name
- HASSEL (NCT07049965)
- Testing
- Suture ligation, Harmonic Scalpel
- Where
- India
- Volunteers
- 60 people
- Sponsor
- GSVM Medical College
Appendicitis Acute
Comparison of Open and Laparoscopic Appendectomy in Pediatric Population
Introduction: In the era of minimally invasive surgery, changing trends are towards laparoscopic surgery, first introduced in 1983.
- Trial name
- Appendicitis (NCT06363318)
- Testing
- Laparoscopic appendicectomy
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- King Edward Medical University
Appendicitis, Perforated Appendicitis
Comparative Study Between Laparoscopic and Open Appendectomy of Complicated Appendicitis
Acute appendicitis is one of the most common surgical emergencies in children. In complicated cases, where the appendix has perforated, become gangrenous, or caused peritonitis and purulent contamination, determining the optimal…
- Conditions
- Appendicitis, Perforated Appendicitis, Gangrenous Appendicitis, Peritonitis
- Trial name
- NCT07879235
- Testing
- Laparoscopic Appendectomy, Open Appendectomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Appendix Rupture, Pain
Virtual Reality for Appendectomy Pain
To determine the impact of VR-Biofeedback and VR-Distraction on pain and medication utilization in children and adolescents undergoing surgery for ruptured appendix.
- Conditions
- Appendix Rupture, Pain, Pain, Postoperative
- Trial name
- NCT04357132
- Testing
- VR-Biofeedback, VR-Distraction
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acute Appendicitis
TAP Block for Laparoscopic Appendicectomy in Adults
Laparoscopic (key-hole) appendicectomy is a minimally invasive procedure when compared to open large bowel resection, but is still associated with a significant amount of pain and discomfort.
- Trial name
- NCT03252561
- Testing
- Ultrasound guided Transversus Abdominis Plane (TAP) bock, Local anaesthetic infiltration of laparoscopic port sites
- Where
- United Kingdom
- Sponsor
- Oxford University Hospitals NHS Trust
Appendicitis
Polymer Clips Versus Endoloops for Closure of the Appendiceal Stump During Emergency Laparoscopic Appendicectomy
The investigators propose a study to compare two methods of closing the stump of the appendix during an emergency excision of the appendix using a keyhole approach.
- Trial name
- PECAS (NCT02726152)
- Testing
- Polymer clips for closure of the appendiceal stump, Endoloops for closure of the appendiceal stump
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Health Service, United Kingdom
Minimally Invasive Surgical Procedures
Homemade Versus Commercialized Single-access Port Devices in Single-incision Laparoscopic Appendectomy
Homemade and commercialized single-assess port devices are two kinds of port devices commonly used for single-incision laparoscopic appendectomy.
- Trial name
- NCT05528003
- Testing
- Commercialized single-access port devices
- Volunteers
- 161 people
- Sponsor
- National Taiwan University Hospital
Acute Appendicitis, Postoperative Pain
Intravenous Lidocaine in Children Undergoing Laparoscopic Appendectomy
Intravenous lidocaine - a potent local anesthetic with analgesic and anti-inflammatory properties has been shown to be an effective adjunct that reduces intra and postoperative opioid consumption and facilitates pain management…
- Conditions
- Acute Appendicitis, Postoperative Pain, Postoperative Nausea and Vomiting
- Trial name
- NCT03886896
- Testing
- Lidocaine
- Where
- Poland
- Volunteers
- 74 people
- Sponsor
- Medical University of Warsaw
Acute Appendicitis, Surgical Site Infection
Are Double-ring Wound-edge Protectors Effective for Preventing Superficial Surgical Site Infection After Open Appendectomy?
This study aims to evaluate the utility of double-ring wound-edge protectors to prevent the development of superficial surgical site infections after open appendectomy.
- Trial name
- sSSI-2RWEPs (NCT04860570)
- Testing
- Double-ring wound-edge protector
- Where
- Spain
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- Hospital Medina del Campo
Perforated Appendicitis
The Impact of IV Acetaminophen on Pain After Appendectomy for Perforated Appendicitis
The objective of this study is to evaluate two standard post-operative pain regimens routinely used after laparoscopic appendectomy for perforated appendicitis.
- Trial name
- NCT02881996
- Testing
- IV tylenol, No IV tylenol, Ketorolac
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Children's Mercy Hospital Kansas City
Appendicitis, Surgery
Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy
This study is designed as a randomized controlled trial with patients assigned to neuromuscular reversal with either sugammadex or neostigmine/glycopyrrolate reversal.
- Trial name
- NCT05256901
- Testing
- Sugammadex, Neostigmine/Glycopyrrolate
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Emory University
Pain, Postoperative
Intraperitoneal Dexmedetomidine for Post-laparoscopic Appendicectomy Pain Management in Children
Fifty two children of American Society of Anesthesiologists (ASA) physical status I and II, aged 8-14 years old, of both gender, with suspected acute appendicitis scheduled for laparoscopic appendicectomy, were included in this…
- Trial name
- NCT03067740
- Testing
- Bupivacaine, Dexmedetomidine
- Where
- Saudi Arabia
- Volunteers
- 56 people
- Sponsor
- Zagazig University
Appendicitis
Nebulized Analgesia for Laparoscopic Appendectomy Trial
The objective of this study is to assess whether the administration of nebulized intra-peritoneal ropivacaine at the onset of surgery, compared with nebulized saline, reduces morphine consumption after laparoscopic appendectomy…
- Trial name
- NALA (NCT02624089)
- Testing
- Ropivacaine, Normal saline
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Chronic or Recurrent Appendicitis
Laparoscopic Appendectomy for Chronic Right Lower Abdominal Pain
It is questionable whether elective appendectomy can effectively reduce pain in persistent or recurrent lower abdominal quadrant pain due to chronic appendicitis.
- Trial name
- NCT00413855
- Testing
- laparoscopic appendectomy or not (surgery)
- Volunteers
- 40 people
- Sponsor
- Maxima Medical Center
Acute Appendicitis, Abdominal Pain (AP)
Preserving or Resecting the Normal Appendix in Patients Undergoing Laparoscopy Surgery for Suspected Appendicitis
When appendicitis is suspected, patients are typically planned for emergency surgery preferably using a laparoscopic approach. Up to 20% of these patients will have a normal appendix, thus not suffering from appendicitis.
- Conditions
- Acute Appendicitis, Abdominal Pain (AP), Diagnostic Laparoscopy, Laparoscopic Appendectomy
- Trial name
- NCT06917612
- Testing
- Normal diagnostic laparoscopy, Negative appendectomy
- Volunteers
- 20,000 people
- Sponsor
- Herlev Hospital
Postoperative Nausea and Vomiting
Preoperative Gastric Volume and PONV in Pediatric Appendectomy Cases
Postoperative nausea and vomiting (PONV) is one of the common complications in the pediatric patient group. Laparoscopic surgeries further increase the risk of postoperative nausea and vomiting due to increased intra-abdominal…
- Trial name
- PGV-PONV (NCT07916077)
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people
- Sponsor
- Ankara Etlik City Hospital
Appendicitis, Pain
Trial on Postoperative Outcomes According to the Number of Trocar During Laparoscopic Appendectomy
Appendicitis is the most common benign inflammatory disease that requires an operation. Laparoscopic appendectomy using three trocar is generally performed, and reveals good surgical outcomes incluing less pain, early recovey…
- Conditions
- Appendicitis, Pain, Complications
- Trial name
- NCT00816933
- Testing
- appendectomy
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- The Catholic University of Korea