Clinical trials: Large Vessel Occlusion
Organic, Including Symptomatic, Mental Disorders, Substance Use
Exploring the Comorbidity Between Mental Disorders and General Medical Conditions
Mental disorders have been shown to be associated with a number of general medical conditions (also referred to as somatic or physical conditions).
- Conditions
- Organic, Including Symptomatic, Mental Disorders, Substance Use, Schizophrenia, Mood [Affective] Disorders
- Trial name
- COMO-GMC (NCT03847753)
- Testing
- Organic Disorders, Substance Use Disorders, Schizophrenia Disorders
- Volunteers
- 5,940,299 people
- Sponsor
- University of Aarhus
Diabetic Retinopathy (DR), Retinal Vein Occlusion (RVO)
High-throughput Large-model-based AI-assisted Diagnosis Using OCT
This observational study aims to establish key technologies for high-throughput, large-model-based AI-assisted diagnosis using optical coherence tomography (OCT) and OCT angiography (OCTA).
- Conditions
- Diabetic Retinopathy (DR), Retinal Vein Occlusion (RVO), Age-Related Macular Degeneration (AMD), Pathologic Myopia
- Trial name
- NCT07249307
- Testing
- No intervention
- Volunteers
- 2,000 people
- Sponsor
- Peking Union Medical College Hospital
Acute Ischaemic Stroke
Endovascular Therapy in Acute Ischaemic Stroke Due to Large Vessel Occlusion
Aim of Study: 1. To develop a standardized patient selection criteria and imaging protocol for endovascular therapy in acute ischaemic stroke (AIS) 2.
- Trial name
- NCT03328403
- Testing
- Aspiration First, Stent retriever first
- Where
- Hong Kong
- Volunteers
- 58 people
- Sponsor
- The University of Hong Kong
Collateral Circulation, Large-artery Occlusion
Study of Collateral Circulation in Patients With Symptomatic Intracranial Anterior Circulation Occlusion
Intracranial artery stenosis is the leading cause of stroke onset or recurrence in Asian. Multiple studies have shown that anterior circulation is most common in intracranial artery stenosis, especially the middle cerebral artery…
- Conditions
- Collateral Circulation, Large-artery Occlusion, Cerebral Infarction
- Trial name
- NCT04091412
- Testing
- Butylphthalide Soft Capsules
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Hebei Medical University
Stroke Code, Large Vessel Occlusion
Evaluation of a Point-of-care Lateral Flow Assay in Glial Fibrillary Acidic Protein (GFAP) and D-dimer in Diagnosis of Large Vessel Occlusion Acute Ischemic Stroke in a Pediatric Hospital
The goal of this study is to test the efficacy of a rapid bedside blood test in determining if a stroke is happening in children who present to the emergency department with stroke symptoms.
- Conditions
- Stroke Code, Large Vessel Occlusion, Acute Ischemic Stroke
- Trial name
- NCT07474675
- Testing
- Point of Care Rapid Assay
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Boston Children's Hospital
Acute Ischemic Stroke, Large Vessel Occlusion
Acute Ischemic Stroke EndoVascular Therapy: a Multicenter REGISTRY Study
A Multicenter Registry of Endovascular Treatment for Acute Ischemic Stroke.
- Conditions
- Acute Ischemic Stroke, Large Vessel Occlusion, Thrombectomy, Thrombosis
- Trial name
- NCT05864638
- Testing
- Endovascular treatment
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Changhai Hospital
Acute Ischemic Stroke
Registration of Acute Ischemic Stroke With Large and Medium-sized Vascular Occlusion in Southwest China(LMVOS)
This study is designed to observe the treatment options in real-world clinical practice as well as the safety and efficacy of different treatment strategies.
- Trial name
- LMVOS (NCT06125236)
- Testing
- Visit at D90
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- Zhengzhou Yuan
Large Vessel Occlusion, Acute Ischemic Stroke
Cerebral Large Vessel Occlusion Stroke Multiomics Biosample Cohort
This multicenter, ambispective cohort study establishes a comprehensive multiomics biobank from five stroke centers, encompassing thrombi, intracranial blood, peripheral arterial/venous blood, and…
- Trial name
- CLOMB (NCT06963489)
- Testing
- Not applicable- observational study
- Where
- 5 sites in China
- Volunteers
- 500 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Cancer
Heparin or M-EDTA in Preventing Catheter-Related Infections and Blockages in Patients at High Risk for a Catheter-Related Infection
RATIONALE: Heparin or M-EDTA may prevent catheter-related infections and blockages in patients at high risk for a catheter-related infection.
- Trial name
- NCT00378781
- Testing
- Heparin, Minocycline-EDTA
- Sponsor
- M.D. Anderson Cancer Center
Healthy Volunteers, Atherosclerotic Heart Disease
ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study
This study will examine genome sequencing in clinical research. Genome sequencing is a process in which researchers analyze (or sequence) part or all of the genome from a single person.
- Trial name
- NCT00410241
- Where
- 2 sites in United States
- Volunteers
- 1,665 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Posterior Circulation Acute Ischemic Stroke Due to Large Vessel Occlusion of the Vertebral or Basilar Artery Needing Endovascular Thrombectomy
PRECISE (PERFUSION IMAGING TO IDENTIFY POSTERIOR CIRCULATION CANDIDATES FOR THROMBECTOMY)
We hypothesize that patients with a favorable Critical Area Perfusion Score (CAPS≤3) on cerebral perfusion imaging will have a favorable response to revascularization by thrombectomy and that patients with a CAPS>3 will not
- Trial name
- SWISS-PRECISE (NCT06375174)
- Testing
- Thrombectomy
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Dr. med. Carlo Cereda
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Ischemic Stroke
Registry for Evaluating Outcome of Acute Ischemic Stroke Patients Treated With Mechanical Thrombectomy.
The Bernese-European RegistrY for ischemic stroke patients treated Outside current guidelines with Neurothrombectomy Devices using the SOLITAIRE™ FR With the Intention For Thrombectomy (BEYOND-SWIFT) is a retrospective…
- Trial name
- BEYOND-SWIFT (NCT03496064)
- Testing
- Successful reperfusion
- Where
- Switzerland
- Volunteers
- 2,000 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Stroke, Stroke Acute
Mechanical Thrombectomy in the Middle East and North Africa: Interim Results from the MEMENTO Registry
The MEMENTO (MEchanical thrMobectomy NETwork for MENA TOgether) Registry is a multicenter, prospective observational study aiming to evaluate the effectiveness, safety, and cost-effectiveness of mechanical thrombectomy (MT) in…
- Conditions
- Stroke, Stroke Acute, Endovascular Procedures, Large Vessel Occlusion
- Trial name
- MEMENTO Regist (NCT06702787)
- Where
- Egypt
- Volunteers
- 1,500 people
- Sponsor
- Middle East North Africa Stroke and Interventional Neurotherapies Organization
Recognition of Thrombectomy Candidate
Implementation of Finnish Prehospital Stroke Scale to Emergency Medical Services
The investigators have developed a simple prehospital stroke scale (FPSS), containing 5 dichotomized items to recognize both large and small artery thrombi of the brain.
- Trial name
- NCT03520335
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Tampere University Hospital
Acute Ischemic Stroke
Registry of Acute Ischemic Stroke With Large- or Medium-vessel Occlusion
This study is designed to observe the treatment options in real-world clinical practice as well as the safety and efficacy of different treatment strategies.
- Trial name
- LOMEVO (NCT05779215)
- Testing
- Visit at D90
- Where
- China
- Volunteers
- 50,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Ischemic Stroke
Gravity Stroke System for Recanalization of Large Vessel Occlusion Strokes
Supernova and Neutron are endovascular mechanical revascularization devices indicated to restore blood flow by removing thrombus from a large intracranial vessel in patients experiencing an acute ischemic stroke within 24 hours…
- Conditions
- Stroke, Ischemic Stroke, Cerebrovascular Disorders, Brain Diseases
- Trial name
- GRASSROOT Reg (NCT07335185)
- Testing
- Supernova revascularization device
- Volunteers
- 3,000 people
- Sponsor
- Gravity Medical Technology, INC
Intra-arterial Thrombectomy
The Efficacy and Safety of Early Rehabilitation in Large Vessel Occlusion Patients After Intra-arterial Thrombectomy: A Prospective Randomized Controlled Trial
Early rehabilitation is feasible for stroke patients is still under debate. In addition, IA thrombectomy has been a new treatment for the past few years and currently no known research exploring the efficacy of very early…
- Trial name
- NCT05764278
- Testing
- exercise
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Endovascular Thrombectomy, Large Vessel Occlusion
Triage of Patients Presenting Beyond 24 Hours With Acute Ischemic Stroke Due to Large Vessel Occlusions (TRACK-LVO Late)
The objective of this study is to create a comprehensive, multi-center, TRACK-LVO registry-linked cohort of consecutive patients with acute ischemic stroke (AIS) caused by large vessel occlusions (LVO) and presenting to each…
- Conditions
- Endovascular Thrombectomy, Large Vessel Occlusion, Acute Ischemic Stroke
- Trial name
- TRACK-LVO Late (NCT06200753)
- Testing
- Mechanical Thrombectomy
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Tianjin Huanhu Hospital