Clinical trials: Lead Exposure
Lead Poisoning
Effects of Iron and/or Zinc Supplementation in Mexican School Children Exposed to Lead
Lead is negatively linked to nutritional status, behavior and cognition in children. Despite extensive knowledge of its toxicity and efforts to reduce exposure, lead continues to be a problem in developed and developing…
- Trial name
- NCT02346188
- Testing
- Ferrous fumarate, Zinc oxide
- Where
- United States
- Volunteers
- 602 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Lead Poisoning
RECLEAN Pilot Study
This is an exposure assessment pilot study tailored for families of construction workers living with a child. The investigators will compare home dust metal levels and resident's blood metal levels before and after an educational…
- Trial name
- RECLEAN (NCT04498845)
- Testing
- In-home assessment plan, Family educational session, Worker take home prevention training
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Boston University
Iron Deficiency, Lead Poisoning
Iron Fortification Trail Using NaFeEDTA in Iron Deficient Lead-exposed Children
In a cross-sectional study allotted by the ethical committee of the ETH Zurich, we are investigating the extent of anemia, iron deficiency and lead intoxication in young children.
- Trial name
- NCT01573013
- Testing
- iron fortified biscuits
- Where
- Switzerland
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Poisoning
Effectiveness of Environmental Measures to Eliminate the Risks of Lead Exposure in Infant Lead Poisoning
Infant lead poisoning is the clinical expression of lead poisoning. This environmental disease, still present in France, is the only notifiable non-infectious disease.
- Trial name
- NCT03640143
- Testing
- venous blood lead
- Where
- France
- Volunteers
- 165 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Lead Poisoning
Social Network Based Intervention to Reduce Lead Exposure Among Native American Children
The purpose of this study is to examine whether adding an inter-generational component to an existing social network-based lay health advisor intervention increases its effectiveness in mobilizing a Native American community to…
- Trial name
- NCT00011661
- Testing
- Education on behaviors to reduce lead exposure
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Lead Poisoning, Lead Poison Children
Evaluation of the Impact of a Personal and Domestic Hygiene Intervention on Lead Exposure in a Community Close to a Mine Dump
The study evaluates the impact of a personal and domestic hygiene intervention on exposure to lead in a community close to a mine dump.
- Trial name
- NCT05265572
- Testing
- Domestic Hygiene and household hygiene Intervention
- Where
- South Africa
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- University of Johannesburg
Lead Toxicity
Iron Supplementation of Lead-exposed Infants
The purpose of this study is to compare the efficacy of iron (12.5 mg as ferrous sulfate) and placebo given for 6 months in preventing the elevation of blood lead concentration in children 6-9 months of age.
- Trial name
- NCT00374790
- Testing
- Ferrous sulfate
- Where
- Uruguay
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cornell University
Amyotrophic Lateral Sclerosis, ALS
Exposure to Neurotoxins as Risk Factors for Amyotrophic Lateral Sclerosis
This study is a follow-up to an earlier study that examined the relationship of This study will examine whether exposure to neurotoxins, such as lead, mercury, solvents, and pesticides, can contribute to amyotrophic lateral…
- Trial name
- NCT00339976
- Where
- United States
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Exposure to Toxic Dust, Elevated Blood Lead Levels
Reducing Lead Dust Exposure in Older Housing
The objective of this study is to assess the effectiveness of portable air filtration (PAF) for mitigating lead dust exposures and reducing childhood blood lead levels in older housing.
- Trial name
- NCT07485608
- Testing
- portable air filtration systems
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Michigan State University
Osteoporosis
Lead Exposure, Genetics, and Osteoporosis Epidemiology
This study's primary objective is to assess the effects of environmental lead exposures and genetic risk factors on the development of osteoporosis in middle-aged women.
- Trial name
- NCT00013637
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Lead Poisoning
Exposure, Dose, Body Burden and Health Effects of Lead
This is a study of the effects that lead has on the health of the central nervous system (for example, memory), peripheral nervous system (for example, sensation and strength in the hands and fingers), kidneys, blood pressure…
- Trial name
- NCT00013819
- Volunteers
- 944 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Lead Exposure, High Blood Lead Level
Lead Exposure Intervention Program
The goal of this clinical trial is to learn if BLL (blood lead level) screening and "healthy home" lead prevention program created in the US is adaptable to a Sub-Saharan African context.
- Trial name
- LEIP (NCT07401251)
- Testing
- Home visit with tailored messages, In-clinic lead risk reduction intervention
- Where
- Kenya
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Washington
Lead Exposure
Treatment of Lead-Exposed Children Trial
The Treatment of Lead-Exposed Children (TLC) clinical trial compared the effect of lead chelation with succimer to placebo therapy.
- Trial name
- NCT00342849
- Testing
- Succimer
- Where
- 4 sites in United States
- Volunteers
- 780 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Attention Deficit Disorder
Attention Deficit Disorder and Exposure to Lead
We are examining the past exposure to lead in 250 well characterized children with ADHD, and a suitable group of controls. Our measure of past exposure is bone lead levels obtained by XRay fluorescence spectroscopy, a relatively…
- Trial name
- NCT00014898
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Lead Poisoning
Lead Mobilization & Bone Turnover in Pregnancy/Lactation
We are examining the role of maternal bone lead turnover during pregnancy and lactation as a potential source of lead exposure for the fetus and the infant (via breast milk).
- Trial name
- NCT00011726
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Occupational Exposure
Study for Promotion of Health in Recycling Lead
Study for Promotion of Health in Recycling Lead (SPHERL) is a prospective 2-year follow-up study of lead workers with exposure levels varying between and within individuals.
- Trial name
- SPHERL (NCT02243904)
- Where
- Belgium
- Volunteers
- 270 people
- Sponsor
- KU Leuven
Lead Poisoning
Early Exposure to Lead and Adolescent Development
This prospective cohort study examines the role of prenatal and early postnatal lead exposure on the neuropsychological status and social adjustment of adolescents enrolled in the Cincinnati Lead Study.
- Trial name
- NCT00011674
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)