Clinical trials: Leukoderma
Vitiligo
Effectiveness of Narrow-band Ultraviolet B Combined With Topical Tacrolimus 0.03% in Treatment of Patients With Vitiligo
The study will compare the effectiveness of combined treatment with NB-UVB and tacrolimus versus NB-UVB alone . Patients will be treated for 6 months and followed up after 3 months .All types of vitiligo will be included except…
- Trial name
- NCT03199664
- Testing
- NB-UVB, NB-UVB & Tacrolimus 0.03%
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- South Valley University
Metabolic Syndrome, Vitiligo
Metabolic Syndrome in Early Onset Versus Late Onset Vitiligo
This study aims at detection of possible associated metabolic syndrome with vitiligo and assessment of possible contribution of the age of onset of vitiligo.
- Trial name
- NCT03622320
- Testing
- Blood sample
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vitiligo Vulgaris
Efficacy and Safety of Pimecrolimus for the Treatment of Vitiligo Vulgaris
Patients with vitiligo vulgaris are treated with Pimecrolimus twice a day during 6 months. After a baseline visit, patient returns for a control visit after 3 and 6 months of treatment.
- Trial name
- NCT00372307
- Testing
- Application of pimecrolimus
- Where
- Belgium
- Volunteers
- 26 people
- Sponsor
- University Hospital, Ghent
Type 1 Diabetes, Autoimmune Diseases
Additional Autoimmune Diseases With Type 1 Diabetes in Pediatrics at Diabetes Diagnosis and During Follow-up
This study aims to describe the prevalence of additional autoimmune diseases and their specific antibodies at type 1 diabetes (T1D) diagnosis, and their incidence rate during follow-up, for children and adolescents.
- Conditions
- Type 1 Diabetes, Autoimmune Diseases, Hashimoto Disease, Graves Disease
- Trial name
- AADT1D (NCT04789993)
- Testing
- No intervention.
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Central Hospital, Nancy, France
Vitiligo
Punch Minigraft Versus Transverse Needling or Combination of Both in Treatment of Non-Segmental Vitiligo
This study is to evaluate the effectiveness and tolerability of autologous punch minigraft, transverse needling technique or combination of both followed by narrow band ultraviolet B phototherapy (311 nm) in the treatment of…
- Trial name
- NCT03872804
- Testing
- Autologous punch mini grafts:, Transverse needling, Punch minigrafts followed by transverse needling
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Mastocytosis
Molecular Mechanisms and Diagnosis of Mastocytosis
Mastocytosis is a disorder characterized by presence of excessive numbers of mast cells in skin, bone marrow and internal organs.
- Trial name
- NCT00336076
- Testing
- Collection of blood and bone marrow
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Michigan
Vitiligo
Janus Kinase 1 in Vitiligo & Psoriasis
Assessment of the level of JAK1 in both vitiligo and psoriasis patients before and after treatment with NB-UVB which is considered a gold standard therapy for both diseases.
- Trial name
- NCT03762551
- Testing
- skin biopsy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vitiligo and Acne Vulgaris
Cutaneous JAK in Vitiligo and Acne Vulgaris.
The Janus kinase/signal transducer and activator of transcription (JAK-STAT) cytokine signaling pathway is an emerging area of interest in dermatology, and emerging evidence suggests that this pathway may play a crucial role in…
- Trial name
- NCT03185312
- Testing
- skin biopsy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Vitiligo, Excimer Laser
Effect Of Topical Prostaglandin F2α Analogs,Fractional CO2 Laser, Excimer Laser Or Their Combination In Treatment Of Vitiligo
Vitiligo is a chronic disease with an unpredictable clinical course, characterized by the appearance of white macules and patches on the skin and mucous membranes due to the disappearance of melanocytes in the affected area.
- Conditions
- Vitiligo, Excimer Laser, Fractional CO2 Laser
- Trial name
- NCT04577027
- Testing
- Topical travoprost 0.004% solution, Fractional CO2 laser, Excimer laser
- Volunteers
- 30 people
- Sponsor
- Assiut University
Vitiligo
A Study To Assess Adverse Events and Effectiveness of Upadacitinib Oral Tablets in Adult and Adolescent Participants With Vitiligo
Vitiligo is a common chronic autoimmune disease that causes the body's immune system to attack its own pigment producing skin cells.
- Trial name
- Viti-Up (NCT06118411)
- Testing
- Upadacitinib, NB-UVB (narrow-band ultraviolet B) Phototherapy
- Where
- 148 sites in United States, Argentina and 17 more
- Volunteers
- 614 people
- Sponsor
- AbbVie
Vitiligo, Healthy
Dermoscopy in Nails
Study types and frequency of nail changes in patients with vitiligocompared to healthy subjects
- Trial name
- NCT06696612
- Testing
- Dermoscopy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Vitiligo
Autologous Non-cultured Epidermal Cell Suspension Transplantation in the Treatment of Vitiligo
To observe the long-term efficacy and safety of autologous non cultured epidermal cell suspension transplantation in the treatment of vitiligo, analyze the correlation between cell density, type, and postoperative efficacy and…
- Trial name
- NCT07187882
- Testing
- Autologous Non-cultured Epidermal Cell Suspension transplantation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University People's Hospital
Vitiligo
Effectiveness of Micro-needling With 5 Fluorouracil Versus Potent Topical Steroids in the Treatment of Limited Vitiligo
The goal of this clinical trial is to learn how well 5 fluorouracil (5FU) with micro-needling works to treat limited vitiligo as compared to strong steroid applied on skin.
- Trial name
- NCT07398807
- Testing
- Microneedling with 5-fluorouracil, Topical application of 0.05% Clobetasol propionate
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Combined Military Hospital (CMH) institute of Medical Sciences Bahawalpur Pakistan
Vitiligo Vulgaris
Online Health Survey of Patients With Vitiligo Vulgaris/ Online Survey of Pediatric Patients With Vitiligo
The study is an on-line survey posted on survey monkey that addresses some demographic and environmental issues that could potentially relate to vitiligo vulgaris onset or disease exacerbation.
- Trial name
- NCT01401374
- Where
- United States
- Volunteers
- 3,258 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Hermansky Pudlak Syndrome
A Longitudinal Study of Hermansky-Pudlak Syndrome Pulmonary Fibrosis
Hermansky-Pudlak Syndrome (HPS) is a rare genetic disease that is associated with oculocutaneous albinism, bleeding, granulomatous colitis, and pulmonary fibrosis in some subtypes, including HPS-1, HPS-2, and HPS-4.
- Trial name
- NCT02368340
- Testing
- Pulmonary function test, Chest CT, Sample collection
- Where
- 5 sites in United States
- Volunteers
- 55 people
- Sponsor
- Vanderbilt University