Clinical trials: Lichen
Lichen Planus, Oral
Treatmant of Oral Lichen Planus With Lycopene
the purpose of this study was to evaluate that if lycopene, a potent antioxidant can be used in the treatment of oral lichen planus.
- Trial name
- NCT00656214
- Testing
- Lycopene
- Where
- India
- Volunteers
- 30 people
- Sponsor
- College of Dental Sciences, India
Oral Lichen Planus
Topical Betamethasone and Clobetasol in Orabase in Oral Lichen Planus
Oral Lichen Planus (OLP) is an autoimmune, chronic inflammatory mucocutaneous disease characterized by pain and burning sensation.
- Trial name
- NCT03026478
- Testing
- Betamethasone Dipropionate, Clobetasol Propionate
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Garlapati Komali
Oral Lichen Planus
Dexamethasone to Treat Oral Lichen Planus
This study will evaluate the effectiveness of dexamethasone 0.01% solution in treating pain associated with oral lichen planus, a chronic disease that causes painful ulcers inside the mouth.
- Trial name
- NCT00111072
- Testing
- dexamethasone 0.01% solution
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Lichen Sclerosus Lesion
Identification of Genetic Variants Associated With Lichen Sclerosus
Lichen Sclerosus (LS) is a common genital skin condition that severely impacts on daily living. LS occurs worldwide but may be more common in the white population.
- Trial name
- GENITALS (NCT07720830)
- Testing
- No Interventions
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gudula Kirtschig
Vulvar Lichen Sclerosus
Characterizing the Microbiome in Postmenopausal Women With Vulvar Lichen Sclerosus
Vulvar lichen sclerosus (LS) is a chronic inflammatory disease, often diagnosed at late stages after scarring has obliterated normal vulvar architecture and severely affected a woman's quality of life.
- Trial name
- NCT05147129
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Texas Southwestern Medical Center
Keloid, Alopecia Areata
Pain Outcomes Following Intralesional Corticosteroid Injections
Corticosteroid therapy, including intralesional and topical applications, has many indications within the fields of Dermatology, Plastic Surgery, and Orthopedics.
- Conditions
- Keloid, Alopecia Areata, Acne, Hypertrophic Scar
- Trial name
- NCT03630198
- Testing
- Corticosteroid with lidocaine, Corticosteroid with normal saline
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Oral Lichen Planus
A Randomized Clinical Trial of the Effect of Pimecrolimus Cream 1% Compared With Topical Corticosteroid in Treatment of Erosive Oral Lichen Planus
The purpose of this study is to compare the effect of topical Pimecrolimus with adcortyl on erosive-atrophic 0ral lichen planus in a randomized clinical trial study.
- Trial name
- NCT01524744
- Testing
- Pimecrolimus ointment, Adcortyl
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Mashhad University of Medical Sciences
Oral Lichen Planus, Oral Carcinoma
Rate of Malignant Transformation and Clinical Characteristics Among an Oral Lichen Planus Cohort: a Retrospective Center Experience
The main objective of this paper will be to evaluate the rate of malignant transformation among a cohort of patients affected by oral lichen planus with long-term follow-up.
- Conditions
- Oral Lichen Planus, Oral Carcinoma, Oral Carcinoma in Situ
- Trial name
- LPO_CMR (NCT06934863)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Catholic University of the Sacred Heart
Oral Lichen Planus
Efficacy of Green Tea Buccal Tablets in Oral Lichen Planus
Is topical application of green tea polyphenols buccal tablet more effective in treatment of patients with symptomatic oral lichen planus in comparison with topical application of corticosteroids and what is the most effective…
- Trial name
- NCT03415165
- Testing
- green tea buccal tablet, Corticosteroids Topical
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Vaginitis, Atrophic Vaginitis
a Flexible Wound Dressing for the Management of Genital Skin Conditions
The objective of the study is to determine the efficacy of 7-0940 in the management of genital skin conditions in female patients
- Conditions
- Vaginitis, Atrophic Vaginitis, Lichen Planus, Lichen Sclerosus
- Trial name
- NCT05396261
- Testing
- Film forming silicone gel (7-0940)
- Where
- Australia
- Volunteers
- 54 people
- Sponsor
- Stratpharma AG
Atrophic Oral Lichen Planus, Erosive Oral Lichen Planus
Therapeutic Effect of Quercetin and the Current Treatment of Erosive and Atrophic Oral Lichen Planus
Lichen planus (LP) is a common chronic inflammatory mucocutaneous disease with an immunologic etiology ,which has number of different clinical forms.
- Trial name
- NCT01375101
- Testing
- Quercetin
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Mashhad University of Medical Sciences
Vulvar Lichen Sclerosus
Tacrolimus Versus Clobetasol Propionate in the Treatment of Vulvar Lichen Sclerosus
Lichen Sclerosus is an inflammatory skin condition affecting mostly the genital area of persons of all ages, gender or race. The most frequent complaint is that of itchiness of the vulva but pain may also occur.
- Trial name
- NCT00757874
- Testing
- Tacrolimus cream, Clobetasol cream
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- Deana Funaro
Oral Lichen Planus
Molecular & Cellular Characterisation of Oral Lichen Planus
The principal research objective is to provide enhanced understanding of the cellular and molecular events important in the pathogenesis of Oral Lichen Planus to enable improved diagnosis and development of novel treatments for…
- Trial name
- NCT04289233
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University of Birmingham
Oral Lichen Planus, Oral Leukoplakia
Intra and Extra Oral Inspection of Oral Mucosa
Dental health professionals have a responsibility to perform routine intra- and extraoral inspection on their patients for detecting abnormalities.
- Conditions
- Oral Lichen Planus, Oral Leukoplakia, Erythroplakia
- Trial name
- NCT04079491
- Testing
- questionnaire survey
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Dalarna County Council, Sweden
Normal Vulval Skin, Lichen Sclerosus
Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval Disease
Can vibrational spectroscopy be used to accurately assess vulval skin conditions? Vulval skin disorders are common and the diagnosis of these conditions can be difficult.
- Conditions
- Normal Vulval Skin, Lichen Sclerosus, High Grade Dysplasia - Usual Type ('VIN 2-3'), High Grade Dysplasia - Differentiated Type ('VIN 2-3')
- Trial name
- Vulval VS (NCT02223975)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Aphthous Stomatitis, Burning Mouth Syndrome
Evaluation and Treatment of Oral Soft Tissue Diseases
This study offers evaluation and treatment of patients with diseases of the mouth or systemic diseases that involve the mouth. The protocol is not designed to test new treatments; rather, patients will receive current standard of…
- Conditions
- Aphthous Stomatitis, Burning Mouth Syndrome, Lichen Planus, Mouth Disease
- Trial name
- NCT00001601
- Testing
- Electrocardiogram, Biopsies, Diagnostic imaging
- Where
- United States
- Volunteers
- 999 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Oral Lichen Planus
Study of Metronidazole and Doxycycline to Treat Oral Lichen Planus and to Compare Their Efficacy With Each Other
Oral lichen planus (OLP) is a chronic inflammatory disorder which causes local irritation,discomfort and subsequent poor dentition and discomfort in eating .
- Trial name
- NCT00484250
- Testing
- metronidazole,doxycycline
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
Oral Lichen Planus
Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus
Bromelain, an enzyme extract derived from pineapples, has shown promise due to its anti-inflammatory and wound-healing properties. However, its efficacy in treating oral mucosal ulcers remains unexplored.
- Trial name
- NCT06981767
- Testing
- Topical Bromelain, 0.1% topical triamcinolone acetonide, Combination of Topical Bromelain and Triamcinolone Acetonide in Orabase
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Patients With Oral Lichen Planus
Assessing LncRNA DQ786243 and IL-17 Expression in Oral Lichen Planus: A Case Control Study
Observational case-control study. The current study aims to assess the salivary expression of lncRNA DQ786243 and IL-17 in OLP, to better understand the pathogenesis of OLP and provide effective targets for OLP therapy.
- Trial name
- NCT04503824
- Testing
- saliva samples
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Oral Lichen Planus
Thyme Honey for Management of Oral Lichen Planus
the study aimed to assess the effect of topical application of thyme honey in comparison to 0.1% triamcinolone acetonide oral paste on the relief of pain and clinical improvement in patients with OLP
- Trial name
- NCT06810752
- Testing
- thyme honey, Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- British University In Egypt