Clinical trials: Local Anaesthesia
Hip Surgery, Hip Arthroplasty
The Quadro-Iliac Plane (QIP) Block in Hip Surgery
The goal of this observational study is to learn about the effectiveness of different locoregional anesthesia techniques, particularly the Quadro-Iliac Plane (QIP) block, in patients undergoing hip surgery, including…
- Trial name
- QIP in hip (NCT07591311)
- Testing
- Fascia iliaca block (FIB)
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- San Giovanni di Dio Hospital
Situational Anxiety, Behavior
Impact of Therapy Dogs on Child Anxiety and Behavior During Local Anesthesia for Dental Procedures
Therapy dogs in dental offices might help anxious children during dental care. Therapy dogs might help children during injection of local anesthetic, when we inject numbing medication before working on the teeth.
- Trial name
- NCT06725134
- Testing
- Therapy dog presence, Standard-of-care basic behavior guidance
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Anesthesia, Local
Type of Needle Bevel on Pain Perception in Children During Inferior Alveolar Nerve Block Anesthesia
fear of the discomfort that comes with anesthetic needle insertion. For dental local anesthesia, needles with a scalpel-designed bevel have been claimed to decrease pain elicited by injection.
- Trial name
- NCT06242743
- Testing
- Scalpel blade needles, standard blade needles
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Hams Hamed Abdelrahman
Regional Anesthesia
Analgesic Efficacy of Ultrasound-guided Bilateral Pecto-intercostal Plane Block in Pediatric Cardiac Surgery
The goal of this study is to compare patients outcome in two groups. the first group will be applied pecto-intercostal fascial block additional to general anesthesia and the second group will not.
- Trial name
- NCT06089798
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Anesthesia
URAISE: Ultrasound Regional Anaesthesia Interpretation Skill Evaluation
Prospective study based on psychometric principles.# To generate a validated test of ultrasound guided regional anaesthesia that can used to differentiate reliably between users of different skill levels.
- Trial name
- URAISE (NCT05668689)
- Testing
- Preliminary testing, Psychometric main study testing (Phase 5)
- Where
- 6 sites in United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Posterior Spine Surgery
Kyphoscoliosis Surgery: Blood Conservation and Analgesia
Since the first spinal fusion by Hibbs 1911, yet anesthesia for correction of scoliosis is challenging due to frequently associated co-morbidities, the extensive nature of surgery and liability for many complications.
- Trial name
- NCT03319563
- Testing
- Local anesthetic-epinephrine, Saline
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Mansoura University
Dental Anxiety, Pain Management
Effectiveness of Virtual Reality Technique on Children
Studying the effect of using virtual reality technique in managing pain, anxiety, and vital signs among pediatric dental patients.
- Conditions
- Dental Anxiety, Pain Management, Pediatric Dentistry
- Trial name
- NCT07722221
- Testing
- Conventional, Virtual reality
- Where
- Syria
- Volunteers
- 64 people
- Sponsor
- Latakia University
Dental Pain and Sensation Disorder, Dental Caries in Children
Local Anesthesia With Computerized Device for Restorative Procedures in Pediatric Patients
The aim of the present study is to assess if there are differences on perceived pain during local anesthesia performed with SleeperOne device or with a traditional syringe in pediatric patients.
- Trial name
- NCT05531435
- Testing
- local anaesthetic injection
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Molar Incisor Hypomineralisation
SleeperOne® 5 Intraosseous Anesthesia in MIH
This randomized split-mouth clinical trial evaluates whether computer-controlled intraosseous anesthesia delivered with the SleeperOne® 5 system reduces pain perception and dental anxiety compared with conventional local…
- Trial name
- CCLAD-MIH (NCT07741487)
- Testing
- SleeperOne® 5 Computer-Controlled Intraosseous Anesthesia, Conventional Local Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Ankara University
Postoperative Pain
Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management
To evaluate the efficacy of bilateral continuous erector spinae blocks (BESB) for postoperative analgesia in children and adolescents undergoing cardiac surgical procedures via sternotomy in the Early Recovery After Surgery…
- Trial name
- NCT04567407
- Testing
- Bilateral erector spinae blocks using ropivacaine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Anesthesia, Local
PDL Anesthesia Versus Local Infiltration
The literature concerning the success and pain scores of PDL injection technique compared with other techniques remains controversial; whereas some studies found no significant difference in pain scores between local infiltration…
- Trial name
- PDL (NCT03173898)
- Testing
- PDL anesthesia versus local infiltration
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Analgesia
Postoperative Analgesia by Epidural vs IV Ketamine Concurrent With Caudal Anesthesia in Pediatric Orthopedic Surgery
Preemptive analgesia can improve postoperative pain management. Ketamine may prevent central sensitization during surgery and result in preemptive analgesia.
- Trial name
- NCT00532662
- Testing
- S(+)-ketamine
- Where
- 2 sites in Iran
- Volunteers
- 40 people
- Sponsor
- Tehran University of Medical Sciences
Oral Health Related Quality of Life OHRQoL
Does Treating Early Childhood Caries Under Local or General Anesthesia Have Varying Effects on OHRQoL
A two-arm randomized control trial is to compare the changes in OHRQoL scores among children treated for ECC under general (DGA) and local anesthesia (LA).
- Trial name
- NCT05761691
- Testing
- Dental treatment
- Where
- Saudi Arabia
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Knee Osteoarthritis, Hip Osteoarthritis
Regional Anesthesia in Total Hip and Knee Arthroplasty
The purpose of this study is to test whether the use of Ropivacaine and Mepivacaine are better in terms of effectiveness, cost, and safety than Bupivacaine as regional anesthetics in elective hip or knee replacement surgery.
- Trial name
- NCT04257682
- Testing
- Bupivacaine, Ropivacaine, Mepivacaine
- Volunteers
- 135 people
- Sponsor
- Ottawa Hospital Research Institute
Dental Anxiety, Pain
Efficacy of Tell-Show-Do Behavior-Management Technique During Local Anesthesia in Preschool Children
This will be a randomized, controlled, parallel-group clinical trial. The aim of this study will be to evaluate the effectiveness of "Tell-Show-Do" Behavior Management Technique versus a Conventional technique (covering the…
- Conditions
- Dental Anxiety, Pain, Infant Behavior, Heart Rate and Rhythm Disorders
- Trial name
- NCT02578160
- Testing
- inferior alveolar and lingual nerve block procedure
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Evelyn Alvarez Vidigal
Regional Anesthesia Morbidity, Post Operative Pain
THE EFFICIENCY OF FASCIAL PLANE BLOCKS IN BARIATRIC SURGERY
Bariatric surgery effectively produces weight loss and reduces obesity-related comorbidities. Although it is mostly performed with minimally invasive techniques, the patients may still suffer from moderate-to-severe pain…
- Conditions
- Regional Anesthesia Morbidity, Post Operative Pain, Bariatric Surgery Candidate
- Trial name
- NCT05284695
- Testing
- Bariatric surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- V.K.V. American Hospital, Istanbul
Pain
The Effectiveness of Sweet Solution Versus Cryotherapy in Reducing Pain During Administration of Local Anesthesia Among Children
the porpose of study to assess The Effectiveness of Sweet Solution Versus Cryotherapy in Reducing Pain During Administration of Local Anesthesia Among Children
- Trial name
- NCT07002528
- Testing
- sucrose solution, Cryotherapy, topical anesthesia
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Scoliosis, Spine Deformity
Post-Hoc Cost-Utility Analysis of Ultrasound-Guided Erector Spinae Plane (ESP) Block Versus Total Intravenous Anesthesia (TIVA) in Posterior Scoliosis Correction Surgery: Evidence From the Egyptian EQ-5D-5L Value Set
Posterior scoliosis correction surgery is associated with sever postoperative pain that necessitate high perioperative opioid doses to alleviate pain .
- Trial name
- NCT07470567
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- National Bank Hospital
Cleft Lip, Cleft Palate +/- Lip
Comparative Study of Regional Nerve Blocks in Primary Cleft Palate Repair
This study will evaluate whether adding a suprazygomatic maxillary nerve block to the standard palatal nerve block improves pain control after cleft palate repair surgery in children.
- Conditions
- Cleft Lip, Cleft Palate +/- Lip, Pain Management, Wound Dehiscence, Surgical
- Trial name
- NCT07892963
- Testing
- Palatal Nerve Block, Suprazygomatic Maxillary Nerve Block
- Volunteers
- 144 people
- Sponsor
- Children's National Research Institute
Anesthesia, Local
Pain Control of Needle-free Versus Needle Injected Local Anesthesia for Pulpotomy of Upper Primary Molars in Children
This is a study that will be conducted on 6 to 8 years old children to compare the needle-less jet injector with the conventional needle attached syringe in terms of efficiency in controlling pain of local anesthetic infiltration…
- Trial name
- NCT03917121
- Testing
- Jet injector, Needle attached dental syringe
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University