Clinical trials: Local Anesthesia
Anesthesia, Conduction, Nerve Block
Neurologic Complications in Peripheral Regional Anesthesia - An Evaluation Based on a Standardized Protocol
To evaluate the incidence of neurologic complications as a consequence of peripheral regional anesthesia, all patients receiving peripheral nerve blocks will be evaluated according to a standardized protocol screening pain…
- Conditions
- Anesthesia, Conduction, Nerve Block, Adverse Effects
- Trial name
- NCT00445016
- Testing
- peripheral regional anesthesia
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- BG Unfallklinik Murnau
Dental Anxiety, Pain Management
Electronic vs. Conventional Syringes: Impact on Pediatric Pain and Anxiety
Study Overview Purpose: To compare pain and anxiety levels in children aged 6-8 during local anesthesia administration using electronic vs. conventional syringes.
- Trial name
- NCT07045116
- Testing
- Electronic anesthesia, Conventional anesthesia
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Randa Omer Ahmed Bashir
Dental Anxiety, Pain Management
Impact of Local Anesthesia Techniques on Children's Dental Treatment Experience
compare the effectiveness of several local anesthetic delivery systems in managing pain, anxiety, behavior, and vital signs among pediatric dental patients.
- Conditions
- Dental Anxiety, Pain Management, Pediatric Dentistry
- Trial name
- NCT07106138
- Testing
- Conventional syringe injection, Star Pen, Comfort-In
- Where
- Syria
- Volunteers
- 112 people
- Sponsor
- Latakia University
Regional Anesthesia
Comparing Postoperative Analgesic Techniques for Umbilical Hernia Repair: A Randomized Trial of Ultrasound Guided Caudal, Erector Spinae, and External Oblique Interfascial Plane Blocks
The aim of this study is to evaluate the efficacy of ultrasound guided Erector block versus caudal block versus external oblique intercostal plane block perioperatively
- Trial name
- NCT06948253
- Testing
- Erector Spinae Plane Block, Caudal Block Anesthesia, External Oblique Intercostal Plane Block
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tanta University
Dermatochalasis, Blepharoptosis
Vibration-Assisted Anaesthesia
Aim of study is to investigate whether a small, non-invasive vibrating device applied to the forehead during local anaesthetic administration reduces the pain of the injection.
- Trial name
- NCT00793988
- Testing
- Vibration-assisted anaesthesia, Switched-off vibrating device
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Postoperative Pain
Postoperative Pain in Neonates After Abdominal Surgery Using Quadratus Lumborum Block
Postoperative pain scores and analgesic requirements will be evaluated in neonates after abdominal surgery, with regional quadratus lumborum block performed at the beginning of the procedure.
- Trial name
- NCT03203031
- Testing
- General anesthesia, Quadratus lumborum block
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hôpital Armand Trousseau
Dental Anxiety, Pain
Effect of Therapeutic Play and Virtual Reality Glasses on Pain and Anxiety in Children
Background: A child's first dental experience plays a crucial role in treatment success and in fostering cooperation during future visits.
- Trial name
- NCT07375056
- Testing
- Intervention 1: Therapeutic Play Group, Intervention 2: Virtual Reality Glasses Group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Local Anesthesia
Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Injection
This study will test the effectiveness of addition of Sodium Bicarbonate as a buffering agent to the anaesthetic solution on minimizing the pain of injection and increasing the onset time and potency of the anaesthetic solution…
- Trial name
- NCT05473819
- Testing
- Buffered Local Anesthesia, Conventional Unbuffered Local Anesthesia
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Conscious Sedation Failure During Procedure, Analgesia
Lidocaine as Local Anesthetics in Children Under Ketamine Sedation
Ketamine seems an obvious choice in the setting of an emergency department in laceration repair. Lidocaine is the local anesthetics widespread used. Ketamine leads to dissociative amnesia.
- Conditions
- Conscious Sedation Failure During Procedure, Analgesia, Anesthesia
- Trial name
- NCT02205502
- Testing
- Lidocaine, Normal saline
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
Cardiovascular Response to Epinephrine
Comparing Cardiovascular Effects of 1:100,000 and 1:200,000 Epinephrine Solutions
The study aim to evaluate systemic response of patients when 2 different concentrations of Epinephrine are injected during inferior alveolar nerve block for wisdom teeth extraction.
- Trial name
- NCT02735018
- Testing
- Epinephrine 1:100,000, Epinephrine 1:200,000
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Postoperative Pain, Chronic Post Operative Pain
Comparative Analysis of Three Locoregional Anesthesia Methods in Breast Tumour Pathology Surgery
The present study compares the Erector Spinae Plane (ESP) block, Pectoral (PECS II) block, and Serratus-Intercostal Fascial Plane (SIFP) block.
- Conditions
- Postoperative Pain, Chronic Post Operative Pain, Breast Tumor, Locoregional Anesthesia
- Trial name
- NCT05185752
- Testing
- SIFP Block Locoregional Interfascial Anesthesic Technique, PECS II block: Locoregional Interfascial Anesthesic Technique, ESP block: Locoregional Interfascial Anesthesic Technique
- Where
- Spain
- Volunteers
- 103 people
- Sponsor
- University of Valencia
Anesthesia, Ostomy
Transversus Abdominis Plane Block in Children Undergoing Ostomy Surgery
The primary objective of this study is to determine if the use of Transversus Abdominis Plane (TAP) blocks reduce early postoperative opioid requirements.
- Trial name
- NCT01136668
- Testing
- Transversus Abdominis Plane Block, Standard
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- The Hospital for Sick Children
Anxiety, Dental
The Efficacy of Lavender and Chamomile Essential Oils Inhalation in Management of Dental Anxiety and Pain in Children Undergoing Local Anesthesia Administration and Primary Tooth Extraction
The Efficacy of Lavender and Chamomile Essential Oils Inhalation in Management of Dental Anxiety in Children Undergoing Local Anesthesia Administration and Primary Tooth Extraction.
- Trial name
- NCT06133868
- Testing
- Lavender and Chamomile Essential Oils
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthesia, Regional
Survey of Regional Anesthesia Practice in Poland
The study is being conducted to gain insight into regional anesthesia practice in polish hospitals specifically asking for methods used, accessibility to equipment and preference for regional blockade and perioperative analgesia.
- Trial name
- AnkietaRA (NCT03923751)
- Testing
- Invitation to regional anesthesia survey
- Where
- Poland
- Volunteers
- 700 people
- Sponsor
- Medical University of Warsaw
Tuberculosis
Local Anesthesia and Tuberculin Skin Test in Infants and Children
The use of local anaesthesia efficiently reduces pain due to needle puncture. However, when tuberculin skin test is performed it is the skin reaction to tuberculin injection that is studied.
- Trial name
- NCT00309673
- Testing
- lidocaine / Prilocaine
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Local Anesthesia Injection Pain
Effectiveness of Laser Photobiomodulation Therapy in Reducing Child Pain During Local Anesthesia Injection
This study aimed to evaluate the impact of laser photobiomodulation therapy used as pre-anesthetic technique to reduce child pain during local anesthesia administration
- Trial name
- NCT05861154
- Testing
- Photobiomodulation, Benzocaine Gel
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Aliaa Hamouda
MIH, Molar-Incisor Hypomineralization
Effects of Silver Diamine Fluoride and Intraoral Cryotherapy on Local Anesthesia in MIH-Affected Molars
Molar-incisor hypomineralization (MIH) is a developmental enamel defect of unclear etiology that affects permanent first molars and often permanent incisors, leading to increased porosity, hypersensitivity, and poor prognosis.
- Conditions
- MIH, Molar-Incisor Hypomineralization, Caries Assessment
- Trial name
- NCT07326241
- Testing
- Standard Local Anesthesia, Intraoral Cryotherapy, Silver Diamine Fluoride (SDF)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Dental Pain, Dental Anxiety and Child Behavior Are Assess in Response to Dental Injection
Effect of Computer-controlled vs. Conventional Injection on Pain and Anxiety in Children
This randomized controlled trial aims to compare the effectiveness of Computer-Controlled automatic injection device versus conventional injection techniques in pediatric dental patients.
- Trial name
- NCT07193342
- Testing
- computer controlled automatic injection (Star pen® system), conventional anesthetic syringe
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Future University in Egypt
Laparoscopic, Ultrasound
Laparoscopic vs Ultrasound-Guided Transversus Abdominis Plane Block vs Laparoscopic Intraperitoneal Instillation of Local Anesthetic in Pediatrics
The aim of this study is to compare laparoscopic -assisted, ultrasound-guided transversus abdominis plane block and laparoscopic intraperitoneal instillation of local anesthetic in pediatrics undergoing inguinal hernia repair.
- Conditions
- Laparoscopic, Ultrasound, Transversus Abdominis Plane Block, Laparoscopic Intraperitoneal Instillation
- Trial name
- NCT06098105
- Testing
- Ultrasound-guided transversus abdominis plane block, Laparoscopic-assisted transversus abdominis plane block, Laparoscopic-assisted intraperitoneal instillation
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Tanta University
Inflamed and Infected Primary Molars in Children, Effectiveness of Buffered Local Anesthesia During Dental Extraction
Evaluate Buffering Local Anesthetic in Inflamed Teeth
This randomized, double-blinded, split-mouth clinical trial evaluates the effect of buffering local anesthetic with sodium bicarbonate in pediatric dental extractions.
- Trial name
- NCT07120594
- Testing
- Unbuffered lidocaine 2% with epinephrine 1:80,000, Buffered lidocaine 2% with epinephrine 1:80,000
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Latakia University