Clinical trials: Local Anesthetic Effectiveness
Pain, Chronic
Lidocaine Infusions for Chronic Pain in Children
This is a study to evaluate the efficacy and safety of lidocaine in the management of chronic pain in children. All participants will receive lidocaine infusion and severity of pain and degree of chronic-pain related disability…
- Trial name
- NCT02983682
- Testing
- Lidocaine Infusion
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- The Hospital for Sick Children
Hypertension
Assessment of Anesthetic Efficacy and Hemodynamic Stability of Two LA Drugs for Hypertensive Patients
Pain control in dentistry is an important factor for reducing the fear and anxiety associated with dental procedures. For tooth extraction, it is mandatory to use resources to manage pain and discomfort such as adequate…
- Trial name
- NCT06927726
- Testing
- 4% Articaine HCL With 1:100,000 Epinephrine, 3% plain mepivacaine HCL
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
Urinary Stress Incontinence
Safety and Efficacy Study on the Implantation of the Tension-Free Vaginal Tape (TVT-Secur) Under Local Anesthesia
The objective was to observe the satisfaction of local anesthesia during the implantation of the TVT-SECUR for the treatment of stress urinary incontinence, with the use of questionnaires completed by the patients, and to…
- Trial name
- NCT00904618
- Testing
- TVT-SECUR - 'Hammock' technique, TVT-SECUR - 'U-Method', Local anesthesia (30 to 40 ml of a mixture of 35 ml of lidocaine 2% and 5 ml of bicarbonate 3%).
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Université de Sherbrooke
Dental Anxiety, Pain
Efficacy of Tell-Show-Do Behavior-Management Technique During Local Anesthesia in Preschool Children
This will be a randomized, controlled, parallel-group clinical trial. The aim of this study will be to evaluate the effectiveness of "Tell-Show-Do" Behavior Management Technique versus a Conventional technique (covering the…
- Conditions
- Dental Anxiety, Pain, Infant Behavior, Heart Rate and Rhythm Disorders
- Trial name
- NCT02578160
- Testing
- inferior alveolar and lingual nerve block procedure
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Evelyn Alvarez Vidigal
Child Behaviour
Comparison of a Needle-free Local Anesthetic Technique With Traditional Syringe [ Needle Syringe] Technique for the Restoration of Primary Molars and Permanent Molars
The goal of this clinical trial is to compare the effectiveness of needle free system and dental needle system [Traditional syringe system] for restoration of Primary and young permanent teeth.
- Trial name
- NCT06448507
- Testing
- INJEX [Needle less anesthesia], Syringe Needle [ Traditional technique]
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- University of Jazan
Molar Incisor Hypomineralization, Anesthesia, Local
Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars
The purpose of this randomized, controlled clinical study is to evaluate if application of 38% SDF increases the efficacy of local anesthesia during operative dentistry on permanent molars affected by molar-incisor hypoplasia…
- Trial name
- NCT05964387
- Testing
- SDF
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pulpitis
Buffered Versus Conventional Local Anesthesia for Pain and Anxiety Reduction in School-Aged Children With Pulpitis
The objective of this clinical trial is to evaluate whether buffered local anesthesia is more effective than conventional local anesthesia in reducing pain responses in school-aged children requiring dental treatment for…
- Trial name
- NCT07638254
- Testing
- Buffered Lidocaine with Epinephrine, idocaine with Epinephrine (Conventional)
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Anesthesia, Local
Comparison of The Effectiveness of Intraligamentary and Mandibular Anesthesia on Mandibular Molar Teeth
This study aimed to compare the effects of mandibular and intraligamentary anesthesia techniques on pain scores during restorative treatment of permanent mandibular molars in pediatric patients.
- Trial name
- NCT05115773
- Testing
- Intraligamentary anaesthesia, Mandibular anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Anesthesia, Local
Cold Vibratory Stimuli on Pain Perception Governing Infiltration Anesthesia in in Children
Local anesthesia injections are sometimes painful, resulting in antagonistic cooperation, fear, and anxiety in children. This study aims to investigate the effectiveness of vibratory and cold stimulation before the injection to…
- Trial name
- NCT05857033
- Testing
- Buccal and direct palatal injection with the aid of Buzzy, Buccal and indirect palatal injection with the aid of Buzzy, Buccal and direct palatal injection without Buzzy
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Alexandria University
Dental Anxiety
Effectiveness Of Magic Tricks Distraction Technique
Dental anxiety among children is a significant challenge in pediatric dentistry, often hindering effective dental care. This clinical study aims to evaluate the effectiveness of two magic tricks distraction techniques (magic rope…
- Trial name
- NCT07075458
- Testing
- Magic Rope Trick, Magic Thumb Sleeves, Tell-Show-Do (TSD)
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Virtual Reality, Anesthesia, Local
Efficacy of VR Distraction During Local Anesthesia in Children
The aim of this study is to compare between active distraction (video game) and passive distraction (cartoon video) using a Virtual Reality ( VR ) device, in reducing injection pain and anxiety associated with local anesthesia in…
- Conditions
- Virtual Reality, Anesthesia, Local, Pain
- Trial name
- NCT05129943
- Testing
- active distraction, passive distraction
- Where
- Syria
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Latakia University
Anxiety, Dental
The Efficacy of Lavender and Chamomile Essential Oils Inhalation in Management of Dental Anxiety and Pain in Children Undergoing Local Anesthesia Administration and Primary Tooth Extraction
The Efficacy of Lavender and Chamomile Essential Oils Inhalation in Management of Dental Anxiety in Children Undergoing Local Anesthesia Administration and Primary Tooth Extraction.
- Trial name
- NCT06133868
- Testing
- Lavender and Chamomile Essential Oils
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Low-level-laser Theraphy, Anesthesia, Local
Anethesia Efficacy on Teeth With MIH (Molar Incisor Hypomineralisation)
Difficulty in achieving anesthesia in teeth with molar incisor hypomineralisation (MIH) is a frequently reported clinical problem.
- Conditions
- Low-level-laser Theraphy, Anesthesia, Local, Molar Incisor Hypomineralization
- Trial name
- MIH (NCT05344014)
- Testing
- Photobiomodulation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Pain, Needle Phobia
The Efficacy of EMLA Cream vs. Synera Patch for Pain Reduction During Venipuncture in Children
This study compares the efficacy of the Synera patch with Eutectic Mixture of Local Anesthetics (EMLA) as a topical anesthetic for venipuncture in pediatric patients.
- Trial name
- NCT00530803
- Testing
- EMLA Cream, Synera Patch
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Montefiore Medical Center
Pain
The Effectiveness of Sweet Solution Versus Cryotherapy in Reducing Pain During Administration of Local Anesthesia Among Children
the porpose of study to assess The Effectiveness of Sweet Solution Versus Cryotherapy in Reducing Pain During Administration of Local Anesthesia Among Children
- Trial name
- NCT07002528
- Testing
- sucrose solution, Cryotherapy, topical anesthesia
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Molar Incisor Hypomineralization
Local Anesthesia in Molar Teeth With Molar Incisor Hypomineralization
To compare responses to electrical pulp test (EPT) and cold test among molar incisor hypomineralization (MIH)-effected and not MIH-effected carious teeth before and after administration of local anesthesia for caries removal.
- Trial name
- NCT04061096
- Testing
- Evaluation of cold test, Evaluation of electrical pulp test, Evaluation of pain during the treatment
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Didem Sakaryali
Pain in Pediatric Dentistry, Dental Anxiety
Effectiveness of Digital Anesthesia Versus Conventional Techniques in Reducing Pain and Anxiety in Children
This multicenter randomized controlled clinical trial was conducted to evaluate the effectiveness of digital anesthesia using a computer-controlled intraosseous system (SleeperOne 5®) compared to traditional local anesthesia…
- Trial name
- DAPAED (NCT06992193)
- Testing
- Digital Anesthesia, Infiltration Anesthesia, Mandibular Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Ege University
Inflamed and Infected Primary Molars in Children, Effectiveness of Buffered Local Anesthesia During Dental Extraction
Evaluate Buffering Local Anesthetic in Inflamed Teeth
This randomized, double-blinded, split-mouth clinical trial evaluates the effect of buffering local anesthetic with sodium bicarbonate in pediatric dental extractions.
- Trial name
- NCT07120594
- Testing
- Unbuffered lidocaine 2% with epinephrine 1:80,000, Buffered lidocaine 2% with epinephrine 1:80,000
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Latakia University
Cesarean Section
Diclofenac vs. Ropivacaine for Cesarean Section
A prospective, randomized, double blind study designed to investigate analgesic efficacy of wound infusion using diclofenac or ropivacaine following Cesarean section performed via a Pfannenstiel incision.
- Trial name
- NCT00801528
- Testing
- Ropivacaine, Diclofenac, Water for injection
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Meir Medical Center
Local Anesthetic Efficacy
Efficacy of Differents Anaesthetics in Mandibular Third Molar Germectomy
Aim: To compare the clinical efficacy of local anaesthetics with articaine 4% or mepivacaine 2% (both with epinephrine 1:100.000) using different anaesthetic techniques to perform germectomy of lower third molars and to assess…
- Trial name
- NCT04465149
- Testing
- Third Molar Germectomy
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli