Clinical trials: Locomotor Pain Disorder
Fibromyalgia, Sexual Dysfunction
Fibromyalgia and Sexual Functıonal Dısorder and Sexual Therapy
investigators aim to re-evaluate the findings of Fibromyalgia in patients whose FSFI scores return to normal levels after sexual therapy, by identifying patients with sexual dysfunction according to the FSFI scale applied in…
- Trial name
- NCT05272345
- Testing
- sexual therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Systemic Lupus Erythematosus (SLE), Diffuse Systemic Sclerosis
YTS109 in Pediatric Relapsed/Refractory Autoimmune Diseases
This exploratory, single-arm, open-label study will evaluate the safety and preliminary efficacy of YTS109 cell therapy in pediatric patients with relapsed/refractory autoimmune diseases, including systemic lupus erythematosus…
- Conditions
- Systemic Lupus Erythematosus (SLE), Diffuse Systemic Sclerosis, Idiopathic Inflammatory Myopathies (IIMs), ANCA Associated Vasculitis (AAV)
- Trial name
- NCT07439029
- Testing
- YTS109 cell
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Children's Hospital of Fudan University
Osteoarthritis
Platelet Rich Plasma Combined With Platelet Rich Fibrin in Management of Temporomandibular Joint Osteoarthritis
Studying effectiveness of prp with prf comparing with prp or prf for mangement of tmj osteoarthritis as result in pain and mandibular movement in adult pt
- Trial name
- NCT06573502
- Testing
- Prp with prf or prp or prf
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Aliaa Babekir Ahmed Mohamed
Arthritis, Juvenile Idiopathic
An Internet-based Self-management Program for Adolescents With Arthritis
The purpose of this study is to demonstrate the effectiveness of the "Taking Charge: Managing JIA Online" Internet intervention, when compared with an attention (static education only websites) control group in improving pain and…
- Trial name
- NCT01572896
- Testing
- Taking Charge: Managing JIA Online, Standard Medical Care and JIA Resource Center
- Where
- 11 sites in Canada
- Volunteers
- 333 people
- Sponsor
- The Hospital for Sick Children
Juvenile Idiopathic Arthritis
A Study of Tocilizumab in Chinese Participants With Systemic Juvenile Idiopathic Arthritis (sJIA)
This Phase IV, multicenter, single-arm, open-label study will evaluate the efficacy and safety of tocilizumab in Chinese participants with sJIA with persistent activity and an inadequate response to non-steroidal…
- Trial name
- NCT03301883
- Testing
- Tocilizumab, NSAIDs, CSs
- Where
- 10 sites in China
- Volunteers
- 62 people
- Sponsor
- Hoffmann-La Roche
Polyarticular-course Juvenile Idiopathic Arthritis (JIA)
Pediatric Arthritis Study of Certolizumab Pegol
A Multicenter, Open-label Study to Assess the Pharmacokinetics, Safety and Efficacy of Certolizumab Pegol in Children and Adolescents With Moderately to Severely Active Polyarticular-course Juvenile Idiopathic Arthritis (JIA).
- Trial name
- PASCAL (NCT01550003)
- Testing
- Certolizumab Pegol (CZP)
- Where
- 36 sites in United States, Argentina and 5 more
- Volunteers
- 193 people
- Sponsor
- UCB BIOSCIENCES GmbH
Preoperative Period, Nutritional Status
Preoperative Nutritional Status in Patients Undergoing Elective Total Knee Arthroplasty and In-hospital Postoperative Complications
Malnutrition has long been linked to postoperative complications and adverse outcomes in a variety of surgical fields , such as increased susceptibility to infection, delayed wound healing, and increased frequency of decubitus…
- Conditions
- Preoperative Period, Nutritional Status, Arthroplasty Knee
- Trial name
- NUTR TKA (NCT03549962)
- Testing
- TKA
- Where
- 2 sites in Hong Kong
- Volunteers
- 626 people
- Sponsor
- Chinese University of Hong Kong
Osteoarthritis
The HIHO Study: Hospital Inpatient vs Home Rehabilitation After Total Knee Replacement
Total knee replacement (TKR) surgery is a common and highly effective treatment option for alleviating the pain and disability caused by chronic arthritis.
- Trial name
- HIHO (NCT01583153)
- Testing
- Hospital Inpatient Rehabilitation, Hybrid Home Programme (HO)
- Where
- 3 sites in Australia
- Volunteers
- 165 people
- Sponsor
- Mark Buhagiar
Osteoarthritis, Knee
Conventional Alignment System Versus Surgical Navigation System in Total Knee Arthroplasty
This is a randomized, controlled, blinded prospective study comparing the use of the usual cutting guides with a palm-sized digital surgical navigation system in unilateral total knee arthroplasty.
- Trial name
- NCT01797731
- Testing
- Digital hand-held surgical navigation system, Conventional tibial extramedullary alignment system
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hospital for Special Surgery, New York
Rheumatoid Arthritis
SonoElastography of Median Nerve in Rheumatoid Arthritis
To assess the role of ultrasonography and SE in detecting the median nerve changes before progression to CTS in patients with RA.
- Trial name
- NCT06135129
- Testing
- Sonoelastography
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Assiut University
Abatacept, Treatment Compliance
Efficacy and Safety of Abatacept Combined With JAK Inhibitor for Refractory Rheumatoid Arthritis
The aim of this study is to observe the clinical efficacy and safety of abatacept combined with JAK inhibitor in the treatment of D2TRA patients
- Conditions
- Abatacept, Treatment Compliance, Rheumatoid Arthritis
- Trial name
- NCT05451615
- Testing
- Janus Kinase Inhibitor, Abatacept
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zhejiang Provincial People's Hospital
Knee Arthropathy
Persona Cohort Nordic Multicenter Study
In this project the investigators wish to: Evaluate intra-operative and postop complications, longer term survivorship and patient reported outcome measures (PROMs) following primary total knee replacement using Persona Total…
- Trial name
- NCT03495232
- Testing
- Zimmer Biomet Persona total knee system
- Where
- 4 sites in Denmark, France and 2 more
- Volunteers
- 700 people
- Sponsor
- Zimmer Biomet
Systemic Juvenile Idiopathic Arthritis With Active Flare
Flare Prevention Study of Canakinumab in Patients With Active Systemic Juvenile Idiopathic Arthritis (SJIA)
This two-part study assessed the sustained efficacy of canakinumab in the double-blind Part II and the ability to taper steroids in the open label Part I.
- Trial name
- β-SPECIFIC 2 (NCT00889863)
- Testing
- canakinumab
- Where
- 73 sites in United States, Argentina and 17 more
- Volunteers
- 177 people
- Sponsor
- Novartis Pharmaceuticals
Osteoarthritis, Hip
Bone Marrow Aspirate Concentrate Use in Hip Osteoarthritis
The purpose of this study is to evaluate the effect of combined Bone marrow aspirate concentrate (BMAC) and Platelet Rich Plasma (PRP) action after a single hip intraarticular injection to young symptomatic patients with primary…
- Trial name
- BMAC (NCT03410355)
- Testing
- BMAC/PRP Injection, Cortisone Injection
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Chronic Fatigue Syndrome, Fibromyalgia
Compare the Medical Conditions of Gulf War Veterans to Non-Deployed Veterans
Primary Hypothesis: Gulf War veterans will have an equal prevalence or mean level of the following medical and psychological conditions frequently reported in the literature compared to a control group of nondeployed veterans…
- Conditions
- Chronic Fatigue Syndrome, Fibromyalgia, Post-Traumatic Stress Disorder, Neurologic Abnormalities
- Trial name
- NCT00032461
- Volunteers
- 2,000 people
- Sponsor
- US Department of Veterans Affairs
Juvenile Idiopathic Arthritis
Internet Self-Management Program With Telephone Support for Adolescents With Arthritis
This study will evaluate the feasibility of "Teens Taking Charge: Managing Arthritis On-line" intervention that will help adolescents with arthritis to better manage their disease and improve their health-related quality of life…
- Trial name
- NCT01011179
- Testing
- Teens Taking Charge, Self-Management
- Where
- 4 sites in Canada
- Volunteers
- 46 people
- Sponsor
- The Hospital for Sick Children
Osteoarthritis, Knee
Outcome Comparison of Two Total Knee Arthroplasty Systems: e.Motion-Pro Versus Genesis II
Recently, E.Motion-PS-Pro (B.Braun-Aesculap, Tuttlingen, Germany), a new mobile bearing knee system with a unique ball and socket post-cam mechanism was developed for use in total knee arthroplasty.
- Trial name
- NCT02276118
- Testing
- device: e.motion PS Pro, device : Genesis II
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Seoul National University Hospital
Knee Osteoarthritis
Long-term Study of The Press Fit Condylar (P.F.C.) Sigma Total Knee Replacement System
The main purpose of this study is to record information from clinical and radiographic examinations and patient assessment questionnaires before surgery and at suitable postoperative intervals to assess the functioning and…
- Trial name
- NCT00734110
- Testing
- P.F.C. Sigma Total Knee System
- Where
- United Kingdom
- Volunteers
- 723 people
- Sponsor
- DePuy International
Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
Comparative Study of Total Knee Arthroplasty Using a Customized-patient Specific Instrument System.
Patient-specific instrumentation (PSI) has been introduced in total knee arthroplasty (TKA) as a new technology for improving accuracy in restoration of the alignment and biomechanics of the lower limb.
- Trial name
- NCT02500160
- Testing
- Patient specific instrumentation (MRI), Patient specific instrumentation (CT)
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kyung Hee University Hospital at Gangdong
Fibromyalgia
Audio Vestibular Assessment in Patients with Fibromyalgia
Fibromyalgia (FM) is a common rheumatic illness distinguished by chronic pain, fatigue, cognitive problems, and functional disability.
- Trial name
- NCT06579560
- Testing
- Audiovestibular assessment in Patients with Fibromyalgia
- Where
- Egypt
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Noha Osman
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