Clinical trials: Long Term Results
Chronic Constipation (CC) (Excluding Constipation Due to Organic Diseases), Irritable Bowel Syndrome With Constipation (IBS-C)
Post-marketing Surveillance of Linaclotide Tablet in Patients With Irritable Bowel Syndrome With Constipation or Chronic Constipation (Excluding Constipation Due to Organic Diseases)
The objective of this study is to evaluate the long-term safety and efficacy of linaclotide in post-marketing use.
- Trial name
- NCT03471728
- Testing
- linaclotide
- Where
- 47 sites in Japan
- Volunteers
- 2,475 people
- Sponsor
- Astellas Pharma Inc
Hidradenitis Suppurativa (HS)
Observational Study Evaluating Long-Term Safety and Effectiveness of Humira in Patients With Hidradenitis Suppurativa
The objective of this study is to evaluate the long-term safety and effectiveness of Humira in patients with Hidradenitis Suppurativa (HS) in real-world clinical practice in Japan.
- Trial name
- NCT03894956
- Where
- 37 sites in Japan
- Volunteers
- 46 people
- Sponsor
- AbbVie
Liver Metastases
Prognosis of One-stage Hepatectomy for Bilobar Colorectal Metastases
It is not rare that two-stage hepatectomy for multiple bilobar colorectal liver metastases (CLM) be left incomplete because of disease progression or technical reasons.
- Trial name
- NCT01683357
- Testing
- Hepatectomy
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- University of Milan
Nosebleed (Epistaxis) - Posterior or Anterior
Long Term Results and Complications After Epistaxis Treatment
The aim of this study is to find the most agreeable and in the long term most efficient treatment for epistaxis.
- Trial name
- NCT02127554
- Where
- Switzerland
- Volunteers
- 591 people
- Sponsor
- University of Zurich
Pulmonary Neoplasm
Effect of Pulmonary Rehabilitation on Perioperative Outcomes in Smoker Patients With Lung Cancer
It is reported that smoker patients (>400 cigarette/year) will suffer more postoperative complications than non-smoker patients after lobectomy.
- Trial name
- PREPOSE (NCT03010033)
- Testing
- pulmonary rehabilitation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Ruijin Hospital
Overactive Bladder
Long-Term Specified Drug Use-results Survey of Betanis Tablets
This study is to evaluate the safety and efficacy of long-term use of Betanis (generic name: mirabegron), and to determine the adherence to treatment with mirabegron.
- Trial name
- NCT01901120
- Testing
- Betanis
- Where
- 8 sites in Japan
- Volunteers
- 1,263 people
- Sponsor
- Astellas Pharma Inc
COPD, Pulmonary Disease, Chronic Obstructive
A Long-term Safety Study of Infliximab in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD).
The purpose of this long-term observational study is designed to collect additional information on incidence of cancer and cause of death among patients who have participated in clinical trials of infliximab in the treatment of…
- Trial name
- NCT00380796
- Testing
- Collection of safety data for Cohort 1
- Where
- 26 sites in United States
- Volunteers
- 88 people
- Sponsor
- Centocor, Inc.
Duodenogastric Reflux
Laparoscopic Total Fundoplication for Duodenogastroesophageal Reflux
After laparoscopic total fundoplication (LTF) 12-15% of patients have persistent reflux symptoms and 20-25% develop gas-related symptoms.
- Trial name
- NCT01741441
- Testing
- laparoscopic total fundoplication
- Where
- Italy
- Volunteers
- 188 people
- Sponsor
- University of Turin, Italy
Coronary Artery Dissection, Spontaneous
Spontaneous Coronary Artery Dissection anaLysIs of the Brazilian Updated Registry
A retrospective and prospective registry will evaluate demographic and angiographic data in patients with spontaneous coronary artery dissection (SCAD) using medical records, invasive coronary angiography, intravascular imaging…
- Trial name
- SCALIBUR (NCT03398850)
- Where
- Brazil
- Volunteers
- 250 people
- Sponsor
- Hospital Israelita Albert Einstein
Hernia
Long-term Results After Endoscopic Total Extraperitoneal Repair of Recurrent Inguinal Hernia
Evaluation of long-term results for chronic pain and impairment of daily activities after endoscopic total extraperitoneal repair of recurrent inguinal hernia with inguinal pain questionnaire (IPQ).
- Trial name
- NCT00683098
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- St. Claraspital AG
Healing Rate, Recurrence
Anal Fistula Plug, a Retrospective Study
In this study, we retrospectively reviewed clinical data of patients who were treated with an anal fistula plug for trans-sphincteric anal fistulas, and evaluated the long-term therapeutic effect of an anal fistula plug and the…
- Conditions
- Healing Rate, Recurrence, Complication
- Trial name
- NCT04319861
- Testing
- Anal fistula plug procedure
- Where
- China
- Volunteers
- 207 people
- Sponsor
- Zhen Jun Wang
Mitral Regurgitation
Edge-To-Edge Technique Used as a Bailout in Case of Sub-Optimal Mitral Repair: Very Long-Term Results
The absence of residual mitral regurgitation (MR) after mitral valve repair is of paramount importance for the long term durability of the valve repair.
- Trial name
- NCT05733988
- Testing
- Bailout edge to edge
- Where
- Italy
- Volunteers
- 81 people
- Sponsor
- Michele De Bonis
Internal Hemorrhoids
Study About Patient Comfort and Long-term Outcome After Stapled Hemorrhoidopexy
The purpose of this study was to determine the influence on Patient comfort after Stapled Hemorrhoidopexy versus Milligan Morgan (two surgical procedures)in third degree circular hemorrhoids.
- Trial name
- NCT01533363
- Testing
- Stapled hemorrhoidopexy, Milligan Morgan
- Volunteers
- 130 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Polycystic Ovary Syndrome
Metformin Treatment in Adolescent Patients With PCOS: A Long-term, Winning Metabolic Choice.
This study aimed to understand whether metformin therapy can improve insulin resistance in adolescent PCOS patients, both during treatment and after discontinuation, and to evaluate its action on the hormonal and metabolic…
- Trial name
- NCT06015594
- Testing
- Metformin
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Obstructive Sleep Apnea
Long-term Impact of Maxillomandibular Advancement Osteotomy on Sleep Apnea Patients
Background Maxillomandibular advancement surgery (MMA) has demonstrated high success rates, improving both the apnea-hypopnea index and associated patient' quality of life (QOL), in patients diagnosed with obstructive sleep apnea…
- Trial name
- MIMOSA (NCT03246477)
- Volunteers
- 12 people
- Sponsor
- AZ Sint-Jan AV
Flexion Contracture of Proximal Interphalangeal Joint, Joint Deformities, Acquired
Rationale and Analysis of the Use of ETDNO in the Treatment of PIPJ Flexion Contracture:
Introduction: Flexion contracture is one of the most frequent complications in finger trauma. The use of orthoses to obtain the best total end range time (TERT) is the most popular method to treat this pathology .
- Trial name
- NCT05465603
- Testing
- ETDNO (Elastic Tension digital neoprene orthosis)
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Vicenç Punsola Izard
Type 2 Diabetes
Specified Drug Use Results Survey of Ipragliflozin Treatment in type2 Diabetes Patients
The objective of this survey is to confirm the safety of Suglat Tablets
- Trial name
- STELLALONGTERM (NCT02479399)
- Testing
- ipragliflozin
- Where
- 8 sites in Japan
- Volunteers
- 11,412 people
- Sponsor
- Astellas Pharma Inc
NPC
IMRT vs 2DRT for NPC Patients
Irradiation of the parotid gland with subsequent long-term xerostomia is a well-recognized complication after radiotherapy for head and neck (HAN) cancers.
- Trial name
- NCT03352778
- Testing
- IMRT, 2DRT
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Interstitial Pneumonia Associated With Polymyositis/Dermatomyositis
A Survey for Long-term Use of Prograf Capsules in Patient With Interstitial Pneumonia
This study is to evaluate the safety and the efficacy of Prograf in patients with interstitial pneumonia associated with polymyositis / dermatomyositis in acute clinical setting.
- Trial name
- NCT02159651
- Testing
- tacrolimus
- Where
- 8 sites in Japan
- Volunteers
- 179 people
- Sponsor
- Astellas Pharma Inc
Chronic Otitis Media
Tegmen Defect Management During Mastoidectomy
In this study, we aimed to discuss our clinical experience on the management of the tegmen defects which were revealed during the mastoidectomy surgeries.
- Trial name
- NCT04374266
- Testing
- physical examination, and computerized tomography
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istanbul Medeniyet University