Clinical trials: Low Mental Wellbeing
HIV-1-infection
Group-Based Intervention to Improve Mental Health and Adherence Among Youth Living With HIV in Low Resource Settings
IMPAACT 2016 was a multi-site, two-arm, individually randomized, controlled study to evaluate whether an Indigenous Leader Outreach Model (ILOM) of trauma-informed cognitive behavioral therapy (TI-CBT) delivered by Indigenous…
- Trial name
- NCT04024488
- Testing
- Youth TI-CBT Intervention Arm, Youth Discussion Control Arm, Caregiver TI-CBT Intervention Arm
- Where
- 8 sites in Botswana, Malawi and 2 more
- Volunteers
- 484 people
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Infant, Extremely Low Birth Weight, Lung Diseases, Obstructive
Growth, Health and Development in Children Born Extremely Preterm
Background: In a national Norwegian cohort of children born before 28 weeks gestation or with a birth weight less than 1000 g born in 1999 and 2000, 372 survived.
- Conditions
- Infant, Extremely Low Birth Weight, Lung Diseases, Obstructive, Disorder of Bone Density and Structure, Unspecified, Cognition Disorders
- Trial name
- PEP11 (NCT01150071)
- Where
- 2 sites in Norway
- Volunteers
- 232 people
- Sponsor
- University of Bergen
Mental Health, Family Relations
An Evaluation of a Family Counseling Intervention ("Tuko Pamoja") in Kenya: a Single Case Series Design
The purpose of this study is to evaluate a family counseling intervention, entitled "Tuko Pamoja" (Translation "We are Together" in Kiswahili).
- Conditions
- Mental Health, Family Relations, Family Conflict, Child Mental Disorder
- Trial name
- C0058 (4A) (NCT03360201)
- Testing
- Tuko Pamoja, "We are Together" in Kiswahili
- Where
- Kenya
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Duke University
Food Insecurity
Fruit and Vegetable Rx (FVRx) + Home Plate
This is a research study to test if fruit and vegetable prescription vouchers (FVRx) and a cooking skills program (Home Plate) can improve dietary quality, food security (access to a sufficient quantity of affordable, nutritious…
- Trial name
- NCT04986046
- Testing
- Home Plate Lite, Home Plate, Fruit and Vegetable prescription
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Anxiety, Wellness, Psychological
Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study
The Fit2Lead prospective cohort study examines the effects of a park-based youth mental health and resilience afterschool program on youth participant mental health, resilience, physical fitness, and violence prevention outcomes.
- Conditions
- Anxiety, Wellness, Psychological, Overweight or Obesity, Hypertension
- Trial name
- F2L (NCT06596265)
- Testing
- Fit2Lead Group 1-2
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Mental Health Issues
Mindmatters: Tutoring and Counseling Program
The tutoring and counseling program for adolescents from low socioeconomic backgrounds facing mental health challenges during the COVID-19 pandemic will be assessed using a randomized controlled trial.
- Trial name
- NCT07007871
- Testing
- Tutoring and Counselling (1), Tutoring and Counselling (2)
- Where
- Hong Kong
- Volunteers
- 170 people
- Sponsor
- Education University of Hong Kong
Post Partum Depression
Sensing Technologies for Maternal Depression Treatment in Low-Resource Settings
In certain low- and middle- income country settings, there is a disproportionate level of untreated postpartum depression that presents both acute and long-term risks to a mother's well-being.
- Trial name
- StandStrong (NCT06253676)
- Testing
- Problem Management Plus (PM+)
- Where
- Nepal
- Volunteers
- 121 people
- Sponsor
- George Washington University
Body Weight Changes, Eating Disorder Symptom
Body Weight Regulation, Disordered Eating Behaviour, and Experiences of Sexual Harassment in Female Martial Art Athletes
Athletes in martial arts compete in categories separated by body weight, hence, many athletes need to adjust their habitual body weight during periods with competition preparation.
- Conditions
- Body Weight Changes, Eating Disorder Symptom, Sexual Harassment, Covid19
- Trial name
- FMAB (NCT04559542)
- Where
- Norway
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Overweight, Obesity
Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study
The Fit2Play prospective cohort study examines the effects of a park-based youth physical activity afterschool program on youth participant fitness and mental health outcomes.
- Conditions
- Overweight, Obesity, Hypertension, Prehypertension
- Trial name
- F2P (NCT06595251)
- Testing
- Fit2Play curriculum
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Mental Health Issue, Development, Child
Development, Usability and Feasibility Pilot Study of a Videogame
Mental health disorders are one of the leading causes of illness globally. The importance of psychosocial skills acquired in early childhood, such as executive functions, inhibitory control, emotional regulation, and social…
- Conditions
- Mental Health Issue, Development, Child, Cognitive Ability, General
- Trial name
- Japi-1 (NCT07048119)
- Testing
- Japi 1.0
- Where
- Chile
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Pregnancy in Adolescence
Teen motHers' ReproductIve and behaVioral Health intErvention in Barbados
The goal of this clinical trial is to learn if an integrated care program can help improve overall health and prevent repeat pregnancy in teen mothers in Barbados.
- Trial name
- THRIVE (NCT07149948)
- Testing
- THRIVE Integrated Care Program
- Where
- Barbados
- Volunteers
- 50 people
- Sponsor
- Hada Fongha Ieong, PhD
Anxiety, Low Mood
Effectiveness of a School Wellbeing Programme for Internalising Problems in Irish Primary School Children
The aim of this study is to assess the effectiveness of a school-based multi-component universal programme for the reduction of internalising problems (i.e. anxiety and low mood) in primary school pupils.
- Trial name
- NCT05061381
- Testing
- A Lust for Life Schools Programme
- Where
- Ireland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Ketogenic Diet, Drug Resistant Epilepsy
Effects of Low Glycemic Index Diet in Children With Drug-resistant Epilepsy
The goal of this clinical trial was to evaluate the effectiveness of a low glycemic index diet (LGID) on seizure frequency, oxidative stress markers and quality of life in children with drug-resistant epilepsy.
- Conditions
- Ketogenic Diet, Drug Resistant Epilepsy, Oxidative Stress, Quality of Life
- Trial name
- NCT06432231
- Testing
- Low glycemic index diet treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Izmir Katip Celebi University
Mental Health
Study of Mental Health and Relationships
The goal of this clinical trial is to test effects of the Great Life Mentoring (GLM) program on the mental health and adaptive functioning on school-age youth (ages 9-16) from low-income families who are receiving outpatient…
- Trial name
- SMART (NCT06534827)
- Testing
- Great Life Mentoring
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Grief, Post Traumatic Stress Disorder
Building and Sustaining Interventions for Children: Task-sharing Mental Health Care in Low-resource Settings
The BASIC study will take place in Kanduyi/Bungoma South Sub-County, in western Kenya, and focuses on children orphaned by one or two parents.
- Conditions
- Grief, Post Traumatic Stress Disorder, Depression
- Trial name
- BASIC (NCT03243396)
- Testing
- Trauma-Focused Cognitive Behavioral Therapy
- Where
- Kenya
- Volunteers
- 956 people
- Sponsor
- Duke University
Depression, Anxiety
RCT of the Effectiveness of Big White Wall Compared to Other Online Support
A randomised controlled trial to compare the effect on wellbeing of an online peer review website (Big White Wall) compared to freely available online information (NHS Moodzone) for people with depression and anxiety.
- Trial name
- REBOOT (NCT02902159)
- Testing
- BWW Online Peer Support, NHS Moodzone Online Information
- Where
- 2 sites in United Kingdom
- Volunteers
- 2,200 people
- Sponsor
- University of Nottingham