Clinical trials: Low Mental Wellbeing
Mental Health Issues
Mindmatters: Tutoring and Counseling Program
The tutoring and counseling program for adolescents from low socioeconomic backgrounds facing mental health challenges during the COVID-19 pandemic will be assessed using a randomized controlled trial.
- Trial name
- NCT07007871
- Testing
- Tutoring and Counselling (1), Tutoring and Counselling (2)
- Where
- Hong Kong
- Volunteers
- 170 people
- Sponsor
- Education University of Hong Kong
Postnatal Depression
Behavioural Activation (BA) for Postnatal Depression in Blackpool
Is Behavioural Activation feasible, acceptable and potentially effective for mothers experiencing post natal depression in Blackpool? Phase 1: A series of single case studies which aim to examine and refine a) the appropriateness…
- Trial name
- BA (NCT04183582)
- Testing
- Behavioural Activation
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- National Society for the Prevention of Cruelty to Children
Depression, Anxiety
RCT of the Effectiveness of Big White Wall Compared to Other Online Support
A randomised controlled trial to compare the effect on wellbeing of an online peer review website (Big White Wall) compared to freely available online information (NHS Moodzone) for people with depression and anxiety.
- Trial name
- REBOOT (NCT02902159)
- Testing
- BWW Online Peer Support, NHS Moodzone Online Information
- Where
- 2 sites in United Kingdom
- Volunteers
- 2,200 people
- Sponsor
- University of Nottingham
Metabolic Syndrome, Inactivity/Low Levels of Exercise
Impact of Lifestyle on Health Maintenance: A Randomized Controlled Trial
This study aims to evaluate the impact of public health interventions on changes in healthy lifestyle habits over time and their subsequent effects on health outcomes.
- Conditions
- Metabolic Syndrome, Inactivity/Low Levels of Exercise, Unhealthy Diet, Unhealthy Alcohol Use
- Trial name
- LifeHealth-RCT (NCT07314957)
- Testing
- Intervention of physical activity, Mediterranean Diet Education, Behavioral: Stress-Resilience Training
- Where
- Croatia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zadar
Maternal Distress, Perinatal Depression
A Common Elements-based Intervention to Improve Maternal Psychological Well-being and Mother-infant Interaction
Background: Millions of children in low resource settings are at high risk of poor development due to factors such as undernutrition, inadequate stimulation and maternal depression.
- Conditions
- Maternal Distress, Perinatal Depression, Development Delay, Language Delay
- Trial name
- NCT04252807
- Testing
- Intervention arm, Treatment as Usual
- Where
- Pakistan
- Volunteers
- 250 people
- Sponsor
- Human Development Research Foundation, Pakistan
Depression Disorders, Affective Disorders
Prevention of Mental Disorders Through Self-efficacy Interventions
Low self-efficacy is a transdiagnostic risk factor for several mental disorders. Self-efficacy refers to one's belief that one is capable of performing a behavior necessary to successfully complete a task or achieve a goal.
- Conditions
- Depression Disorders, Affective Disorders, Prevention, Substance Use Disorders
- Trial name
- SELFTIE (NCT06738953)
- Testing
- Cognitive-Behavioral Intervention to increase Self Efficacy
- Where
- Germany
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Health and Medical University Potsdam
Depression
E-MhGAP Intervention Guide in Low- and Middle-income Countries: Proof-of-concept for Impact and Acceptability
Two strategies will be compared for training and supervising primary care workers delivering mental health services. Both strategies will use the World Health Organization mental health Gap Action Program-Intervention Guide.
- Trial name
- EMILIA (NCT04522453)
- Testing
- paper-based version of mental health Gap Action Program-Intervention Guide, digital version of the mental health Gap Action Program-Intervention Guide
- Where
- 2 sites in Nepal, Nigeria
- Volunteers
- 3,351 people, healthy volunteers welcome
- Sponsor
- George Washington University
Infant, Extremely Low Birth Weight, Lung Diseases, Obstructive
Growth, Health and Development in Children Born Extremely Preterm
Background: In a national Norwegian cohort of children born before 28 weeks gestation or with a birth weight less than 1000 g born in 1999 and 2000, 372 survived.
- Conditions
- Infant, Extremely Low Birth Weight, Lung Diseases, Obstructive, Disorder of Bone Density and Structure, Unspecified, Cognition Disorders
- Trial name
- PEP11 (NCT01150071)
- Where
- 2 sites in Norway
- Volunteers
- 232 people
- Sponsor
- University of Bergen
Body Weight Changes, Eating Disorder Symptom
Body Weight Regulation, Disordered Eating Behaviour, and Experiences of Sexual Harassment in Female Martial Art Athletes
Athletes in martial arts compete in categories separated by body weight, hence, many athletes need to adjust their habitual body weight during periods with competition preparation.
- Conditions
- Body Weight Changes, Eating Disorder Symptom, Sexual Harassment, Covid19
- Trial name
- FMAB (NCT04559542)
- Where
- Norway
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Food Insecurity, Food Insecurity Among Children
Giving Healthy Meal Kits and Cooking Lessons to Rural Families With Food Insecurity.
The goal of this clinical trial is to learn if providing healthy meal kits to food insecure families can help lessen the social and emotional impacts of food insecurity on kids and their caregivers in rural Maine.
- Conditions
- Food Insecurity, Food Insecurity Among Children, Social Emotional Wellness, Caregiver Stress
- Trial name
- NCT06869993
- Testing
- Meal Kit plus Mobile Culinary Medicine Education
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- MaineHealth
Pregnancy, Child Development
Improving Maternal and Child Health Through Prenatal Fatty Acid Supplementation
The purpose of the study is to test whether nutritional supplementation during pregnancy is associated with 1) improved maternal health during pregnancy; 2) improved infant birth and neurodevelopmental outcomes, and 3) whether…
- Trial name
- NAPS (NCT02647723)
- Testing
- DHA, Sugar pill
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Overweight, Obesity
Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study
The Fit2Play prospective cohort study examines the effects of a park-based youth physical activity afterschool program on youth participant fitness and mental health outcomes.
- Conditions
- Overweight, Obesity, Hypertension, Prehypertension
- Trial name
- F2P (NCT06595251)
- Testing
- Fit2Play curriculum
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Anxiety, Wellness, Psychological
Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study
The Fit2Lead prospective cohort study examines the effects of a park-based youth mental health and resilience afterschool program on youth participant mental health, resilience, physical fitness, and violence prevention outcomes.
- Conditions
- Anxiety, Wellness, Psychological, Overweight or Obesity, Hypertension
- Trial name
- F2L (NCT06596265)
- Testing
- Fit2Lead Group 1-2
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Mental Health
Novel Methods for Implementing Measurement-Based Care for Youth in Low-resource Environments
This study will visit 4 community mental health clinics in Washington state and work with clinic staff to find out if staff are regularly evaluating clinical outcomes using questionnaires (which is also called measurement-based…
- Trial name
- NIMBLE (NCT05644756)
- Testing
- IMPACT Methods to Identify and Prioritize Determinants (Challenge I), Challenge and Match strategies to Prioritized Determinants (Challenge II)
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Arthritis, Psoriatic, Psoriasis
Mind Matters: A High Touch, Low Cost Approach to Improving Mental Health Outcomes in Patients With Psoriatic Diseases
Despite advances in effective psoriatic disease treatment, the disease still has a serious impact on mental health and well-being of millions of patients.
- Trial name
- NCT05571696
- Testing
- Immune Strength
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Elaine Husni
Chronic Low Back Pain
Physical Activity and Exercise for Disability and Improving Mental Health in Elderly With Chronic Low Back Pain
This study evaluated the effects of a combined physical activity and structured exercise program on disability and mental health in elderly individuals suffering from chronic low back pain.
- Trial name
- NCT07178561
- Testing
- Exercises for lower back, Exercises and Physical Activity Program, Advices
- Where
- Palestinian Territories
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Ketogenic Diet, Drug Resistant Epilepsy
Effects of Low Glycemic Index Diet in Children With Drug-resistant Epilepsy
The goal of this clinical trial was to evaluate the effectiveness of a low glycemic index diet (LGID) on seizure frequency, oxidative stress markers and quality of life in children with drug-resistant epilepsy.
- Conditions
- Ketogenic Diet, Drug Resistant Epilepsy, Oxidative Stress, Quality of Life
- Trial name
- NCT06432231
- Testing
- Low glycemic index diet treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Izmir Katip Celebi University
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Anxiety, Low Mood
Effectiveness of a School Wellbeing Programme for Internalising Problems in Irish Primary School Children
The aim of this study is to assess the effectiveness of a school-based multi-component universal programme for the reduction of internalising problems (i.e. anxiety and low mood) in primary school pupils.
- Trial name
- NCT05061381
- Testing
- A Lust for Life Schools Programme
- Where
- Ireland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Substance Use Disorder (SUD), Rural Health
Reducing Parental Substance Use and Enhancing Family Resilience Among Rural Families Through Ohio START
The goal of this observational study is to learn about the roles played by parental activity spaces and social networks in reducing parental substance use and promoting child and family health outcomes in the context of Ohio…
- Conditions
- Substance Use Disorder (SUD), Rural Health, Family Resilience, Child Maltreatment
- Trial name
- Ohio START (NCT07278427)
- Testing
- Ohio START (Ohio Sobriety, Treatment, and Reducing Trauma)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Ohio State University