Clinical trials: Lower Extremity Fractures
Tibial Fractures
Immobilization Versus Observation in Children With Toddler's Fractures: a Prospective Randomized Controlled Trial
Toddler's fractures of the tibia are by definition non-displaced and of a stable pattern. Children have thickened periosteum compared with adults, which therefore may impart stability to the fracture without the need for…
- Trial name
- NCT01926795
- Testing
- Short leg cast, No Immobilization
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Prisma Health-Upstate
Tibial Fractures
Stem Cells and Tibial Fractures
The aim of this trial is to determine the safety and tolerability of expanded autologous progeny of an adult CD34+ (haemopoietic) stem cell subset when infused directly into the tibial artery of patients with recent tibial…
- Trial name
- STIF (NCT00632034)
- Testing
- CD34+ haemopoietic stem cells
- Where
- United Kingdom
- Sponsor
- Imperial College London
Hypotension, Hip Fractures
Heart and Renal Failure in Hip Fracture Surgery
Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension.
- Conditions
- Hypotension, Hip Fractures, Renal Insufficiency, Heart Injuries
- Trial name
- NCT03532919
- Testing
- Serum Tropinin
- Where
- Sweden
- Volunteers
- 105 people
- Sponsor
- Sahlgrenska University Hospital
Tibial Fractures
ACTiF- Assessment of Closed Tibial Fractures
The purpose of this study is to find out the good and bad effects of an investigational drug called CP-533,536 in patients with closed fracture of the tibial shaft undergoing internal fixation using reamed inter-locked IM nailing…
- Trial name
- NCT00533377
- Testing
- CP-533, 536, Standard of Care, CP-533,536
- Where
- 56 sites in United States, Australia and 9 more
- Volunteers
- 276 people
- Sponsor
- Pfizer
Patellar Dislocation, Recurrent, Patellar Dislocation
JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction
The goal of this observational study is to learn about the outcomes of medial patellofemoral ligament (MPFL) reconstruction for the treatment of recurrent patellar instability.
- Conditions
- Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation
- Trial name
- NCT06883396
- Testing
- Medial Patellofemoral Ligament (MPFL) Reconstruction
- Where
- 16 sites in United States
- Volunteers
- 850 people
- Sponsor
- Hospital for Special Surgery, New York
Ligament Injury, Knee Injuries
Clinical-instrumental Evaluation and Assessment of Return to Sports Activity in Patients Surgically Treated for Isolated "Stener-like" Lesions of the Medial Collateral Ligament (MCL) or in the Context of Multiligament Injuries and Articular Fractures
The knee is a complex joint stabilized by four main ligaments: the anterior and posterior cruciate ligaments and the medial and lateral collateral ligaments.
- Trial name
- STENER_MCL (NCT07174219)
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- Stefano Zaffagnini
Accidental Falls, Bone Fracture
Flooring for Injury Prevention Trial
This study will evaluate the efficacy of novel compliant flooring in reducing injuries due to falls in a long-term care facility, determine the cost effectiveness of this intervention, and assess perceptions about compliant…
- Conditions
- Accidental Falls, Bone Fracture, Traumatic Brain Injury, Head Injuries, Closed
- Trial name
- FLIP (NCT01618786)
- Testing
- SmartCell flooring, Plywood flooring
- Where
- Canada
- Volunteers
- 151 people
- Sponsor
- Dr. Stephen Robinovitch
Stress Fracture, Ultrasound Therapy
Comparison of Ultrasound and X-ray as Screening Tests for Diagnosis of Lower Extremity Stress Fracture.
Hypothesis: Diagnostic ultrasound is an appropriate screening test for acute stress fracture in the lower extremity and is superior to x-ray.
- Conditions
- Stress Fracture, Ultrasound Therapy, Musculoskeletal Ultrasound
- Trial name
- NCT03116360
- Testing
- Diagnostic Ultrasound
- Volunteers
- 200 people
- Sponsor
- University of Virginia
Hip Fractures
Patient-Centered Education After Hip Fracture Surgery
This randomized controlled trial aims to evaluate the effect of a structured patient-centered educational program on postoperative outcomes among patients undergoing hip fracture surgery.
- Trial name
- PCE-HFS (NCT07739225)
- Testing
- Structured Patient-Centered Educational Program.
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hip Fractures
The Safety of Anesthesia Management for Traumatic Hip Surgery in Elderly
Trauma for hip joint is common in old people. Anesthesia in these types of old patients carries more risk than the adult population.
- Trial name
- NCT02692989
- Testing
- Hip fracture surgery and anesthesia
- Where
- Jordan
- Volunteers
- 1,270 people
- Sponsor
- University of Jordan
Compartment Syndrome Traumatic Lower Extremity, Compartment Syndrome Traumatic Upper Extremity
Clinical Trial of a New Device for Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment Syndrome
Compartment syndrome remains a very serious complication of lower extremity trauma and/or procedural cases that involved lower or upper extremity surgery.
- Trial name
- NCT04012723
- Testing
- MY01 Continuous Compartmental Pressure Monitor
- Where
- 5 sites in Canada
- Volunteers
- 100 people
- Sponsor
- MY01 Inc.
Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified
A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements
This study is a prospective, randomized, double-blind clinical trial evaluating whether intraoperative intravenous lidocaine infusion (IVLI) reduces opioid requirements and improves postoperative pain control in children…
- Conditions
- Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified, Fracture Elbow, Fracture Fixation
- Trial name
- NCT07552766
- Testing
- Lidocaine Infusion, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Nemours Children's Clinic
Tibial Fractures
Virtual Reality for Tibial Eminence Fractures
Tibial eminence fracture, a bony avulsion of the anterior cruciate ligament (ACL) from its insertion on the intercondylar eminence,1 was first described by Poncet in 1875.
- Trial name
- NCT04722081
- Testing
- physical therapy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- South Valley University
Diaphyseal Femur Fracture
Comparative Study Between Operative and Non-Operative Management of Femoral Shaft Fractures in Children
The goal of this clinical trial was to compare the management of pediatric femoral shaft fractures using either Thomas splint traction or Elastic Stable Intramedullary Nailing (ESIN).
- Trial name
- ESIN-THOMAS (NCT07483944)
- Testing
- Thomas splint, ESIN (Elastic Stable Intramedullary Nails)
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University
Femoral Fractures, Pain, Postoperative
Efficacy Study of Femoral Nerve Block in Children With a Femur Fracture
The purpose of this study is to examine the efficacy of the use of Marcaine in femoral nerve blocks and hematoma blocks for post operative pain relief for femoral shaft fractures in a pediatric population.
- Trial name
- NCT01294098
- Testing
- Marcaine
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Washington University School of Medicine
Osteoporosis
CONFIRM EXTENSION - Long-term Follow-up Study of Patients Treated with AGN1 LOEP
The study is designed as a multi-center study within Europe in up to 60 patients treated with the AGN1 LOEP Kit in CONFIRM. This will be a non-randomized and non-blinded study.
- Trial name
- NCT04511364
- Testing
- Clinical imaging is performed during the 24 and 60 month follow-up visits
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- AgNovos Healthcare, LLC
Femur Fracture
Spica Casting in Pediatric Femur Fractures: Study of Single Leg Versus Double Leg Spica Casts
Prospective randomized controlled trial comparing use of single leg spica with double leg spica casts in the treatment of pediatric femur fractures in children ages 2 through 6 years old.
- Trial name
- NCT01293916
- Testing
- Spica casting
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hip Fractures
Hemiarthroplasty Versus Total Hip Replacement for Intracapsular Hip Fractures
In England each year over 9,000 people fracture their hip. Most of these are elderly females with the fracture occurring after a fall.
- Trial name
- NCT02998359
- Testing
- Hemiarthroplasty, Total hip arthroplasty
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Peterborough and Stamford Hospitals NHS Foundation Trust
Procedural Sedation
Low-Dose Intravenous Ketamine Bolus Versus Conventional Technique
Abstract Background: Ketamine has been introduced as one of the most common drugs, administered to sedate children for different painful procedures in the emergency department (ED) but administration in higher dosage causes some…
- Trial name
- NCT03499886
- Testing
- Ketamine Hydrochloride 50Mg/1mL Solution for Injection, Ketamine Hcl 50Mg/Ml Inj
- Where
- 2 sites in Iran
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Hip Fractures (ICD-10 72.01-72.2)
Time on Feet After Hip Fracture Event
With simple technology investigators can map how long it takes for a patient with a hip fracture to be helped and encouraged to stand and walk in the days following the injury.
- Trial name
- TOFFEE (NCT06700031)
- Testing
- Inertial measurement unit
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Region Skane