Clinical trials: Lower Urinary Tract Disorder
Nephrocalcinosis
Alkaline Citrate Treatment to Lower the Risk of Nephrocalcinosis in Preterm Infants
Preterm infants are at risk to develop nephrocalcinosis. Incidence numbers vary according to birth weight and gestation age. Very low birth weight infants have the highest risk index, with ~ 7-10 % of preterm infants developing…
- Trial name
- NCT00249951
- Testing
- Alkaline citrate
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University of Cologne
Overactive Bladder
Acupuncture Combined With Mirabegron in the Treatment of OAB
Introduction: As conventional treatments for overactive bladder (OAB) have not yet shown satisfactory results, new approaches are needed.
- Trial name
- ACWMITTOOAB (NCT06181019)
- Testing
- 50 mg of mirabegron, acupuncture combined with mirabegron.
- Where
- China
- Volunteers
- 75 people
- Sponsor
- The Affiliated Ganzhou Hospital of Nanchang University
Urinary Incontinence
A Long-Term Extension Study of OnabotulinumtoxinA (BOTOX®) for Urinary Incontinence Due to Neurogenic Detrusor Overactivity
This study will evaluate the long-term safety and efficacy of onabotulinumtoxinA (botulinum toxin Type A; BOTOX®) for the treatment of urinary incontinence due to neurogenic detrusor overactivity in participants who successfully…
- Trial name
- NCT01852058
- Testing
- OnabotulinumtoxinA
- Where
- 30 sites in United States, Belgium and 6 more
- Volunteers
- 95 people
- Sponsor
- Allergan
Urinary Incontinence
Treatment of Persistent Urinary Incontinence in Children
The purpose of this study is to determine whether surgical section of the filum terminale in children, when added to standard medical therapy, will result in a reliable and clinically-significant improvement in two main markers…
- Trial name
- NCT00124046
- Testing
- Surgery, Medical Treatment
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of British Columbia
Lower Urinary Tract Symptoms, Posture Disorders in Children
Examination of Trunk and Lower Extremity Biomechanics in Children With LUTD.
This study aimed to examine trunk and lower extremity biomechanics among children with lower urinary tract dysfunction (LUTD). It was targeted to pioneer including biomechanical changes into treatment if detected in the trunk and…
- Conditions
- Lower Urinary Tract Symptoms, Posture Disorders in Children, Muscle Weakness Condition, Urinary Incontinence in Children
- Trial name
- NCT05299827
- Testing
- The same evaluation methods were used for both groups.
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Bipolar Plasmakinetic TURP Vs Monopolar TURP in the Treatment of Lower Urinary Tract Symptoms
Randomized controlled trial with one-year follow-up comparing intra, peri and postoperative outcomes for plasmakinetic transurethral resection of prostate (PK-TURP) and monopolar transurethral resection of prostate (M-TURP) in…
- Conditions
- Prostatic Hyperplasia, Lower Urinary Tract Symptoms, Transurethral Resection of Prostate
- Trial name
- NCT03936244
- Testing
- Transurethral Resection of the Prostate (TURP)
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario de Fuenlabrada
Enuresis, Nocturnal, 2 (Disorder)
Ability to Awaken in Nonmonosymptomatic Enuresis
To evaluate the effect of controlling lower urinary tract symptoms (LUTS) with anticholinergics on improving the ability to awaken (AA) in children with nonmonosymptomatic enuresis and evaluate the potential implication of…
- Trial name
- NCT02845648
- Testing
- anticholinergic
- Volunteers
- 119 people
- Sponsor
- Seoul National University Hospital
Multiple Sclerosis (MS), Neurogenic Bladder Disorder
Essential Oils for Urinary Symptoms in Multiple Sclerosis Patients
The goal of this clinical trial is to learn if essential oil aromatherapy works to improve urinary symptoms in adults with multiple sclerosis. It will also learn about the safety of essential oil use in this population.
- Conditions
- Multiple Sclerosis (MS), Neurogenic Bladder Disorder, Urinary Incontinence (UI), Urinary Urgency
- Trial name
- AROMA-MS (NCT07599189)
- Testing
- Essential Oil Blend (Lavender, Rosemary), Neutral Carrier Oil (Apricot Kernel Oil)
- Where
- 2 sites in Algeria
- Volunteers
- 60 people
- Sponsor
- University of Oran 1
Overactive Bladder
A Trial Evaluating the Clinical Efficacy and Safety of Hibero SR (Mirabegron) 50 mg and Ditropan (Oxybutynin Chloride) 10 mg in Children Between 5 and 18 Years With Overactive Bladder (OAB)
The purpose of this study was to assess the efficacy of Hibero (Mirabegron) versus active control (Ditropan: Oxybutynin Chloride) in the treatment of pediatric subjects (5 to < 18 years of age) with overactive bladder.
- Trial name
- NCT06181591
- Testing
- Mirabegron 50 MG, Oxybutynin Chloride 5 MG
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Mayer-Rokitansky-Kuster Syndrome
Urogynecological and Sexual Functions After Vecchietti Operation
The aim of this study was to establish the urogynecological and sexual functions after Vecchietti operation.
- Trial name
- NCT03809819
- Testing
- laparoscopic Vecchietti vaginoplasty, FSFI questionnaire, UDI-6 questionnaire
- Volunteers
- 26 people
- Sponsor
- Medical University of Lublin
Benign Prostatic Hyperplasia
Pelvic Floor Muscle Exercise for Lower Urinary Tract Symptoms After Surgery for Benign Prostatic Hyperplasia.
This study aims to evaluate the effectiveness of pelvic floor muscle exercise (PFME) on improving lower urinary tract symptoms (LUTS), postvoid residual volume (PVR), and quality of life in patients undergoing surgery for benign…
- Trial name
- BPH LUTS PFME (NCT07293442)
- Testing
- pelvic floor muscle exercises
- Where
- 2 sites in Taiwan
- Volunteers
- 46 people
- Sponsor
- Taipei Medical University WanFang Hospital
Bladder Exstrophy, Urinary Incontinence
Muscle Derived Cell Therapy for Bladder Exstrophy Epispadias Induced Incontinence
The aim of this study is to study safety, tolerability and efficacy of muscle derived cell (MDC) therapy in children with bladder exstrophy epispadias induced urinary incontinence.
- Trial name
- MDC (NCT01011777)
- Testing
- MDC
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Johns Hopkins University
Spinal Cord Injuries (SCI), Urinary Retention
Clinical Trial of Abdominal Breathing for Urinary Retention After Spinal Cord Injury
Randomized controlled trials were conducted in patients with urinary retention after spinal cord injury. The effects of abdominal breathing training on pelvic floor muscle tone, muscle strength and residual urine volume in…
- Trial name
- NCT06964256
- Testing
- Abdominal breathing exercises, Control group: intermittent catheterization, Experimental group: intermittent catheterization
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Qilu Hospital of Shandong University
Lower Back Pain Chronic, Urinary Incontinence
Functional Improvement With Abdominoplasty
The study investigates the impact of abdominoplasty in the post partum population on the symptoms of back pain and urinary incontinence.
- Conditions
- Lower Back Pain Chronic, Urinary Incontinence, Recti Diastasis, Abdominoplasty
- Trial name
- NCT03143959
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- The Caps Clinic
Overactive Bladder
Urinary Biomarkers in Overactive Bladder in Children
It is a single-center, prospective, interventional, single-arm study. Aim is to investigate which variables are significantly correlated with prolonged anticholinergic treatment (>6 months) in children with overactive bladder…
- Trial name
- NCT02704013
- Testing
- Oxybutynin
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Children's Hospital Zagreb
Prostate Cancer, Urinary Incontinence
Prospective RCT on Post Prostatectomy Urine Leak
Objectives: Primary: Comparison of proportion of patient achieving continence between the four arms at 6 months. Secondary: Comparison of time to achieve continence between the four arms.
- Trial name
- NCT02367404
- Testing
- Duloxetine, Pelvic Floor Muscle Training
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Institut Mutualiste Montsouris
Overactive Detrusor, Neurogenic Bladder
Safety and Efficacy Evaluation of Oxybutynin Topical Gel In Children With Neurogenic Bladder
This study will evaluate the safety and efficacy of Oxybutynin Chloride 10% Topical Gel in children 3 to less than 17 years old, who have overactive bladder due to a neurogenic condition.
- Trial name
- NCT01192568
- Testing
- Oxybutynin
- Where
- 10 sites in United States
- Volunteers
- 52 people
- Sponsor
- AbbVie
Refractory Overactive Bladder
A Study to Compare the Efficacy and Safety of Ultrasound Guided Lead Implantation for Sacral Neuromodulation (SNM) in Subjects With Overactive Bladder (OAB) With X-Ray Guided Technique
Overactive bladder(OAB,Urgency) was determined by International Continence Society as Urinary urgency, usually accompanied by frequency and nocturia, with or without urgency urinary incontinence, in the absence of urinary tract…
- Trial name
- NCT02946723
- Testing
- ultrasound, X-ray
- Volunteers
- 30 people
- Sponsor
- Beijing Pins Medical Co., Ltd
Flank Pain, Urinary Bladder, Overactive
Therapeutic Merit of Solifenacin in the Mitigation of Ureteral Stent-induced Pain and Lower Urinary Tract Symptoms
Most ureteral stent insertions follow ureteroscopy procedures for stone management. Stents are essentially designed to prevent the blockage of the ureter.
- Trial name
- NCT01381120
- Testing
- Solifenacin succinate treatment, Oxycodone and acetaminophen combination treatment
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Barrie Urology Associates
Overactive Bladder, Neurogenic Detrusor Overactivity
Single Dose Study to Measure Blood Levels and Safety of a Drug for Children With Overactive Bladder
The purpose of this study is to evaluate blood levels of solifenacin succinate (the study drug) in children with neurogenic detrusor overactivity after taking a single oral dose.
- Trial name
- NCT01539707
- Testing
- Solifenacin succinate suspension 5 mg
- Where
- 7 sites in Belgium, Canada and 5 more
- Volunteers
- 14 people
- Sponsor
- Astellas Pharma Inc