Clinical trials: Lung Function
Bypass Complication, Respiratory Complication
Aortic Cross Clamping Time, and Postoperative Respiratory Function
Does the duration of cardiopulmonary bypass, and aortic cross clamping affects the post operative pulmonary function.
- Trial name
- NCT03072784
- Testing
- aortic cross clamping
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- Assiut University
Cystic Fibrosis, Lung Disease
Magnetic Resonance Imaging (MRI) for Early Diagnosis of Cystic Fibrosis (CF)
In patients with Cystic Fibrosis (CF) the clinical course of lung disease is crucial for individual prognosis and life expectancy.
- Trial name
- NCT00760071
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- German Cancer Research Center
Asthma
The Effect of Cow Milk Consumption on Respiratory Symptoms and Pulmonary Functions in Asthmatic and Non Asthmatic Children
the investigators hypothesis is that milk consumption, either in the acute phase and through prolonged exposure, does not cause or increase respiratory symptoms or airway inflammation.
- Trial name
- NCT02745899
- Testing
- Cow milk, Soy milk
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pulmonary Hypertension
Study of Remodulin® in Pediatric Pulmonary Hypertension With Single Ventricular Physiology After Fontan Surgery
The aim of this study is to determine the safety and efficiency of Remodulin®（Treprostinil Injection）to reduce the pulmonary arterial pressure and prevent pulmonary hypertension (PH) after Fontan operation with univentricular…
- Trial name
- NCT02865733
- Testing
- Remodulin, distilled water
- Volunteers
- 36 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Resuscitation, Neonatal Prematurity
Monitoring Neonatal Resuscitation Trial
This is a randomized trial to determine if a visible respiratory function monitor (RFM) displaying realtime measurements of delivered inflations improves clinical providers ability to perform positive pressure ventilation (PPV)…
- Conditions
- Resuscitation, Neonatal Prematurity, Positive-Pressure Respiration
- Trial name
- MONITOR (NCT03256578)
- Testing
- New Life Box Respiratory Function Monitor
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- University of Pennsylvania
Child, Only
Use of Virtual Reality in Children Undergoing Surgery
Aim: Early mobilization and exercise after surgery are very important to reduce the impact on lung function. The aim of this study was to compare the effects of early mobilization with virtual reality and conservative…
- Trial name
- NCT06882382
- Testing
- conventional physiotherapy, Virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Mustafa Kemal University
Cystic Fibrosis
Effect of the CFTR-modulating Triple Therapy Elexacaftor - Tezacaftor - Ivacaftor
The aim of this study is to investigate the frequency distribution, cytokine profile and function of peripheral, mononuclear leukocyte populations (monocytes, NK cells, T/B lymphocytes) and their correlation to clinical and…
- Trial name
- NCT05576324
- Testing
- Elexacaftor / Ivacaftor / Tezacaftor
- Where
- Germany
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Emphysema
Safety Study of Endobronchial Transplantation of Autologous Mesenchymal Stem Cells (MSCs) in Emphysema Patients
The purpose of this study is evaluating the safety of endobronchial transplantation of autologous mesenchymal stem cells derived bone marrow in patients with emphysema.
- Trial name
- NCT01758055
- Testing
- Autologous MSCs transplantation
- Where
- Iran
- Volunteers
- 12 people
- Sponsor
- Arda Kiani
Pediatric Cancer, Inspiratory Muscle Training
The Effect of Inspiratory Muscle Training on Pediatric Cancer Patient
The aim of this study is to examine the effects of inspiratory muscle training on respiratory functions, functional capacity, fatigue and quality of life in pediatric cancer patients who have recently completed treatment.
- Trial name
- NCT06597552
- Testing
- Training Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people
- Sponsor
- Medipol University
Lung Cancer, Exercise Capacity
Physical Functioning Throughout Lung Cancer Treatment
This trial investigates the impact of lung cancer treatment on physical status, symptoms and quality of life. Furthermore this trial investigates possible underlying causes and consequences of deconditioning.
- Conditions
- Lung Cancer, Exercise Capacity, Physical Activity, Quality of Life
- Trial name
- LUCAT (NCT02493114)
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Pulmonary Regurgitation After Repair of Tetralogy of Fallot
Tetralogy of Fallot Seed Grant
Patients with pulmonary regurgitation after surgical correction of ToF over 13 years old will be recruited from the UCSF adult congenital heart disease clinic.
- Trial name
- NCT00722826
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of California, San Francisco
Systemic Inflammatory Response Syndrome (SIRS), Leukocyte Disorders
Effects of Cardiopulmonary Bypass (CPB)-Leukocyte Filtration on Interleukins Serum Levels and Pulmonary Function
To test the hypothesis that leukocyte filtering during cardiopulmonary bypass (CPB) might reduce the inflammatory response and protect the lungs against the acute injury
- Conditions
- Systemic Inflammatory Response Syndrome (SIRS), Leukocyte Disorders, Complications Due to Coronary Artery Bypass Graft
- Trial name
- PulmFunction (NCT01469676)
- Testing
- Filtering group LG-6, Pall Biomedical Products
- Volunteers
- 22 people
- Sponsor
- University of Sao Paulo
Preoxygenation
Physiological Effects of Different Preoxygenation Strategies
The goal of this clinical trial is to evaluate the performance and physiological effects of different preoxygenation devices in healthy adult and pediatric volunteers (children aged 5-12 years).
- Trial name
- PREOXY II (NCT07564050)
- Testing
- Nasal cannula (NC), Non-rebreather mask (NRM), Non-rebreather mask (NRM) plus Nasal cannula (NC)
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Chronic Kidney Disease Stage 2, Chronic Kidney Disease Stage 3
Preserving Kidney Function in Children With Chronic Kidney Disease
Pediatric chronic kidney disease (CKD) results from health conditions that reduce kidney function for >3 months. It can progress to end-stage kidney disease (ESKD), which requires dialysis or kidney transplant.
- Conditions
- Chronic Kidney Disease Stage 2, Chronic Kidney Disease Stage 3, Pediatric Kidney Disease
- Trial name
- PRESERVE (NCT05169411)
- Testing
- Blood pressure, Urine protein
- Where
- United States
- Volunteers
- 20,240 people
- Sponsor
- Children's Hospital of Philadelphia
Pulmonary Function Assessment, Disease Free Survival
Pulmonary Watershed Topographic Map Navigation for Lung Nodule Resection
A method of ICG counterstaining localization under target artery occlusion without cutting，It's a new method of localization of small pulmonary nodules.
- Conditions
- Pulmonary Function Assessment, Disease Free Survival, NSCLC, Stage I
- Trial name
- NCT06404164
- Testing
- Wedge resection under watershed analysis method
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Congenital Diaphragmatic Hernia
Measurement of Lung Area at Chest Radiography to Define the Prognosis in Newborns With CDH
CDH represents a malformative disorder characterized by an incomplete diaphragm formation. This results in poor lung development (pulmonary hypoplasia), associated with altered vascularization of the lung (pulmonary…
- Trial name
- NeoAPACHE (NCT04396028)
- Testing
- data collection
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Pulmonary Arterial Hypertension
The Effects of Drug Candidate CS1 on Lung Structure and Function Utilizing FRI
Explore the impact of drug candidate CS1 on pathological vascular remodeling of small pulmonary arteries in the disease pulmonary arterial hypertension (PAH).
- Trial name
- NCT06907693
- Testing
- CT Pulmonary Angiography Scan
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Prisma Health-Upstate
Post Covid-19 Condition
Functional Ability, Symptoms and Quality of Life in Patients With Post Covid-19 Condition
Up to 20% of patients with Covid-19 develop symptoms that last more than 3 months, which is known as long Covid or Post-Covid-19 condition.
- Trial name
- LC-cohort (NCT05699512)
- Testing
- Multiprofessional, tailored rehabilitation
- Where
- Finland
- Volunteers
- 400 people
- Sponsor
- Helsinki University Central Hospital
Hepatitis B Virus Infection, Children
Entecavir With or Without Pegylated Interferon α-2b in Children Aged 3-6 Years With Immune-Active Chronic Hepatitis B
This study aims to evaluate the efficacy and safety of entecavir monotherapy versus sequential entecavir plus pegylated interferon α-2b in achieving functional cure in immune-active, HBeAg-positive children aged 3-6 years with…
- Conditions
- Hepatitis B Virus Infection, Children, Chronic Hepatitis B
- Trial name
- NCT07345611
- Testing
- Entecavir, Entecavir + Pegylated interferon α-2b
- Volunteers
- 60 people
- Sponsor
- Qing-Lei Zeng
Cerebral Palsy, Respiratory Function
Inspiratory Muscle Training in Children With Cerebral Palsy: Effects on Respiratory and Motor Functions
This study investigates the effect of inspiratory muscle training on respiratory parameters, trunk control, upper extremity function and swallowing in patients with cerebral palsy aged 5-18 years.
- Conditions
- Cerebral Palsy, Respiratory Function, Balance, Swallowing
- Trial name
- NCT07041593
- Testing
- Inspiratory muscle training and standard neurodevelopmental physiotherapy (SNP), Standard neurodevelopmental physiotherapy (SNP)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Sadık Emre ÇELEBİ