Clinical trials: Lung Function
Scoliosis Idiopathic
Effect of Hippotherapy and Schroth Exercise on Pulmonary Function and Aerobic Capacity in Idiopathic Scoliosis
BACKGROUND: Idiopathic scoliosis has been identified as a common spinal malalignment that negatively impacts the respiratory system and physical conditioning in adolescents.
- Trial name
- NCT04833868
- Testing
- hippotherapy and schroth exercise, schroth exercise
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- Batterjee Medical College
Respiratory Distress Syndrome In Premature Infants, Bronchopulmonary Dysplasia
High Frequency Oscillatory Ventilation Combined With Intermittent Sigh Breaths: Effects on Lung Volume Monitored by Electric Tomography Impedance.
Background Ventilator induced lung injury (VILI) remains a problem in neonatology. High frequency oscillatory ventilation (HFOV) provides effective gas exchange with minimal pressure fluctuation around a continuous distending…
- Conditions
- Respiratory Distress Syndrome In Premature Infants, Bronchopulmonary Dysplasia, Ventilator-Induced Lung Injury, Functional Residual Capacity
- Trial name
- NCT01962818
- Testing
- HFOV combined with sigh breaths
- Where
- Australia
- Volunteers
- 16 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
SARS-CoV-2 Infection
Pulmonary Function in Non-hospitalized Adults and Children After Mild COVID-19
The study investigates whether patients with mild SARS-CoV-2 infection, who stayed at home during their infection and weren't hospitalized, have any persisting sequelae in pulmonary function.
- Trial name
- NCT06318208
- Testing
- lung function testing
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- University of Rostock
Langerhans Cell Histiocytoses
Characterization of Pulmonary Langerhans Cell Histiocytosis
Very recent studies indicate that a high percentage of HCL, about 50%, have mutations in the B-RAF oncogene. The development of ultrasensitive methodologies capable of identifying these mutations in bronchoalveolar lavage will…
- Trial name
- NCT03093727
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Asthma
Progression of Airway Obstruction in Childhood Asthma
Distinct patterns of loss in pulmonary function were identified in children with mild to moderate asthma participating in a 10-year observation period during the NHLBI Childhood Asthma Management Program.
- Trial name
- NCT00873873
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- National Jewish Health
Cystic Fibrosis (CF)
Epididymis Protein 4 and Pulmonary Function With Quality Improvement Protocol Among Cystic Fibrosis Patients
To implement a quality improvement plan aimed at achieving a 5% increase in the Forced expiratory volume in 1st second (FEV1) (% predicted value) in cystic fibrosis (CF) patients with impaired pulmonary function parameters over…
- Trial name
- NCT06915961
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Ain Shams University
Lung Cancer
Respiratory Muscle Function Changes and Effects of Chest Physiotherapy Education Interventionin Advanced Lung Cancer
The purpose for the 1st phase of this study are to exam longitudinal changes and the impact of various treatments on the respiratory muscle function, and the relations with dyspnea, functional capacity, quality of life, 6- and…
- Trial name
- NCT01743586
- Testing
- Chest physiotherapy education intervention
- Where
- Taiwan
- Volunteers
- 102 people
- Sponsor
- National Taiwan University Hospital
Asthma
Effect of Air Pollution on Long-Term Asthma Severity and Lung Function in Children
Asthma can be caused by many factors, including mold, pollen, and other airborne pollutants. The purpose of this study is to evaluate the effect that air pollution has on the long-term severity of asthma symptoms and lung…
- Trial name
- FACES (NCT00336050)
- Volunteers
- 315 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
COVID-19 Pandemic, Dyspnea; Cardiac
Covid-19 Infection and Long-term Cardiovascular Symptoms
From the registry of professor Kojuri clinic , those with Covid-19 infection were selected and was contacted and asked about the cardiovascular symptoms, 1 year after the covid infection
- Conditions
- COVID-19 Pandemic, Dyspnea; Cardiac, Chest Syndrome, Functional Cardiac Disorder
- Trial name
- NCT05715879
- Testing
- covid infection, admission to hispital
- Where
- Iran
- Volunteers
- 879 people
- Sponsor
- Shiraz University of Medical Sciences
Obstructive Pulmonary Diseases, Restrictive Lung Disease
Database of All Patients Who Have Undergone Pulmonary Function Testing at Singapore General Hospital
The purpose of this study is to create a prospective database of all patients who have undergone pulmonary function testing from which the investigators can study the clinical phenotypes of various respiratory conditions.
- Conditions
- Obstructive Pulmonary Diseases, Restrictive Lung Disease, Cough, Dyspnea
- Trial name
- NCT01601288
- Where
- Singapore
- Volunteers
- 17,000 people
- Sponsor
- Singapore General Hospital
Staphylococcus Aureus Pneumonia, Lung Diseases
Mucoid Staphylococcus Aureus in Cystic Fibrosis Airways
Recently, the investigators described a new mucoid phenotype of Staphylococcus aureus cultured from the airways of cystic fibrosis (CF) patients.In this observational study, the investigators plan to determine the prevalence of…
- Conditions
- Staphylococcus Aureus Pneumonia, Lung Diseases, Cystic Fibrosis, Lung Function Decreased
- Trial name
- mucostaph (NCT04171583)
- Where
- 13 sites in Austria, Germany
- Volunteers
- 628 people
- Sponsor
- University Hospital Muenster
Adolescent Development
Inspiratory and Expiratory Muscle Training in Adolescent Volleyball Players
This study will investigate the effects of inspiratory and expiratory muscle training on respiratory muscle strength, pulmonary function, and performance status in adolescent athletes
- Trial name
- NCT06759779
- Testing
- inspiratory muscle training, expiratory muscle training
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Gazi University
Asthma
Study In Airway Physiology In Children SERETIDE DISKUS ® Inhlaer and FLIXOTIDE® Inhaler Are Trademarks of GSK Group of Companies.
Comparison of two asthma treatments by lung function measures.
- Trial name
- NCT00169546
- Testing
- Salmeterol/fluticasone propionate, Fluticasone propionate
- Where
- 2 sites in New Zealand, United Kingdom
- Volunteers
- 64 people
- Sponsor
- GlaxoSmithKline
Cystic Fibrosis (CF)
A Precision Medicine Approach to Assess Protein Function Loss and the Potential for CFTR Function Restoration in Cystic Fibrosis and Related Disorders
This multicenter translational research study integrates diagnostic analyses and ex-vivo functional testing to support future clinical trials evaluating the safety and efficacy of CFTR modulator treatments in individuals with…
- Trial name
- VALPERPRO-CFTR (NCT07889973)
- Where
- 3 sites in Italy
- Volunteers
- 165 people
- Sponsor
- Istituto Giannina Gaslini
Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
Duration of Continuous Positive Airway Pressure and Pulmonary Function Testing in Preterm Infants
The primary aim of this study is to quantify and compare changes in lung volumes (as measured by functional residual capacity) in premature infants stable on continuous positive airway pressure (CPAP), and then randomized to two…
- Trial name
- NCT02249143
- Testing
- CPAP and room air
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Oregon Health and Science University
Pulmonary Arterial Hypertension
Exercise Capacity Respiratory Muscle Strength Dyspnea and Physical Activity in Pediatric Pulmonary Arterial Hypertension
The primary aim of this study was to evaluate exercise capacity, respiratory muscle strength, pulmonary function, dyspnea and physical activity levels in pediatric PAH patients and compare them with healthy controls.
- Trial name
- NCT05124015
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Gazi University
Chronic Kidney Diseases
Skeletal and Respiratory Muscle Strength, Pulmonary Function, Exercise Capacity and Physical Activity in Pediatric Chronic Kidney Disease
Studies examining musculoskeletal strength, respiratory function and muscle strength, physical activity level and exercise capacity in children with CKD and evaluating the relationships between these parameters have not been…
- Trial name
- NCT05354726
- Testing
- Assessments parameters
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Asthma in Children, Asthma
Telemonitoring of Lung Function by Spirometry
Asthma is the most common respiratory disorder in children that causes breathing problems. The patients may have respiratory symptoms such as cough, wheeze, or short of breath.
- Trial name
- NCT04447664
- Testing
- Inclouded telespirometry system
- Where
- Hungary
- Volunteers
- 52 people
- Sponsor
- Szeged University
Chronic Lung Disease of Prematurity, Bronchopulmonary Dysplasia
Relationship Between EIT and Respiratory Status in Very Preterm Infants
Electrical Impedance Tomography (EIT) is a non-invasive imaging technique that can measure lung function in real time. This study will follow premature infants to see if EIT can help predict which infants will be successful in…
- Conditions
- Chronic Lung Disease of Prematurity, Bronchopulmonary Dysplasia, Premature Lungs
- Trial name
- NCT06609135
- Testing
- Sentec LuMon Device (EIT system), Sentec Digital Monitoring System (transcutaneous CO2 monitor)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Lawrence Rhein
COVID-19 Respiratory Infection
Lung Structure-Function In SurVivors of Mild and SEvere COVID-19 Infection: 129Xe MRI
In this study the Investigators aim to deploy UTE and HP 129Xe MRI for structural and functional evaluation of persistent lung abnormalities in COVID-19 survivors.
- Trial name
- LivCovidFree (NCT05014516)
- Testing
- 129Xenon gas
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- The Hospital for Sick Children