Clinical trials: Lung Function Testing
Limb-girdle Muscular Dystrophy
A Study of the Natural History of Participants With LGMD2E/R4, LGMD2D/R3, LGMD2C/R5, and LGMD2A/R1 ≥ 4 Years of Age, Who Are Managed in Routine Clinical Practice
This study will follow participants who are screened and confirmed with a genetic diagnosis of Limb-girdle muscular dystrophy type 2E (LGMD2E/R4), Limb-girdle muscular dystrophy type 2D (LGMD2D/R3), Limb-girdle muscular dystrophy…
- Trial name
- NCT04475926
- Where
- 26 sites in United States, Belgium and 8 more
- Volunteers
- 205 people
- Sponsor
- Sarepta Therapeutics, Inc.
Cystic Fibrosis
Study to Evaluate the Safety and Efficacy of Ciprofloxacin (Inhaled) in Patients With Cystic Fibrosis
To evaluate the change in forced expiratory volume (FEV1) from baseline to Day 28-30 between Cipro Inhale-treated and placebo-treated subjects after a 4-week treatment period.
- Trial name
- NCT00645788
- Testing
- Ciprofloxacin (Cipro Inhale, BAYQ3939)
- Where
- 86 sites in United States, Australia and 7 more
- Volunteers
- 288 people
- Sponsor
- Bayer
Bronchial Asthma
Bronchial Asthma & Its Exacerbation
Our goals is to assess : 1¬_ the role of spirometer in case of asthma exacerbation 2_hematological parameters (N/L ratio \& platelet indices \&CRP )in asthma exacerbation for diagnosing and classifying asthma severity and…
- Trial name
- NCT06331897
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Exercise Induced Asthma, Exercise Induced Bronchospasm
Evaluation of Exercise Induced Bronchoconstriction Using a Novel Automated Digital Clinical Decision System
The primary objective of this study is to assess if the unstandardized field exercise challenge test (ECT) using AsthmaTuner can be performed independently by youths that have been investigated for asthma.
- Conditions
- Exercise Induced Asthma, Exercise Induced Bronchospasm, Pediatric Respiratory Diseases
- Trial name
- NCT05162703
- Testing
- AsthmaTuner
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Asthma
Predictors of Asthma Exacerbations in Children
The purpose of this study is to determine whether parameters of the pulmonary function tests and the bronchial hyperresponsiveness to methacholine are predictors of asthma exacerbations.
- Trial name
- NCT01449435
- Testing
- Methacholine challenge testing
- Where
- Germany
- Volunteers
- 75 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Cystic Fibrosis in Children, Exercise Capacity
Comparison of Different Functional Capacity Tests in Cystic Fibrosis Patients With Acute Pulmonary Exacerbation
The aim of this study to investigate and compare functional capacity with different tests and to evaluate the relationship between functional capacity and quality of life during acute pulmonary exacerbation in children with…
- Trial name
- NCT04174664
- Testing
- 1-minute sit to stand test
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Hacettepe University
Respiratory Function Tests
Is There a Difference in Pulmonary Functions and Craniovertebral Angle Among Adolescent Based on Smart Phone Usage
The smartphones have become a necessity for most adolescents as they are used for communication and entertainment and education purposes especially in the period of COVID pandemic.
- Trial name
- NCT05847127
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Maryan Mamdouh Fayez
Cystic Fibrosis
Transfer Impedance in Cystic Fibrosis
This study aims to determine whether respiratory system transfer impedance (Ztr) may fill an important clinical function by providing a reproducible, valid, and sensitive measure of airway obstruction in people with CF.
- Trial name
- Ztr (NCT00743158)
- Where
- United States
- Sponsor
- Boston Children's Hospital
Cystic Fibrosis
Novel Point-of-care Sweat Chloride Testing Device for Monitoring CFTR Function
This study is being done to test a device called micro Sweat Test Patch (mSTP or µSTP). The study team will compare the standard of care (SOC) method of sweat testing with a novel sweat test technique using an integrated micro…
- Trial name
- SWEAT CF (NCT07414810)
- Testing
- micro Sweat Test Patch (mSTP), Sweat Testing using SOC
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Emory University
Asthma (Diagnosis)
Respiratory Admittance by Oscillometry in Children
Oscillometry is a pulmonary function testing technique suited for children because it does not require specific respiratory maneuvers like spirometry.
- Trial name
- ArsEIB (NCT07771608)
- Volunteers
- 144 people
- Sponsor
- Central Hospital, Nancy, France
Asthma
Testing the Effects of Temperature & Humidity on Children With and Without Asthma in an Environmental Climatic Chamber
The goal of this clinical study is to learn how different temperature and humidity conditions affect breathing, lung function, exercise capacity, symptoms, and other physical responses in children and youth aged 11 to 18 years…
- Trial name
- NCT07864506
- Testing
- Controlled Temperature and Humidity Exposure
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ontario Institute of Technology
Inadequate; Pulmonary Function, Newborn
Use of ICON™ to Detect Hemodynamic Variables During Dexmedetomidine Sedation in Children Undergoing Pulmonary Function Test
To collect and analyze the physiologic data of the ICON™ during dexmedetomidine (DEX) sedation for neonatal pulmonary function testing.
- Trial name
- NCT03205943
- Sponsor
- Boston Children's Hospital
Fear Anxiety, Pulmonary
Preparation Methods on PFT Performance
Background: Successful spirometry in children depends on adequate cooperation and correct performance of respiratory maneuvers. Although several preparation strategies have been proposed, evidence comparing their effects on both…
- Conditions
- Fear Anxiety, Pulmonary, Performance Assessment
- Trial name
- NCT07713225
- Testing
- Verbal Instruction with Demonstration, Animation-Assisted Preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Selcuk University
End Stage Renal Disease on Dialysis
Pulmonary Function Tests in Children and Adolescents With End Stage Renal Disease On Regular Hemodialysis
to study pulmonary function tests in children with ESRD on regular HD and its correlation with dialysis duration and other various risk factors
- Trial name
- NCT06106438
- Volunteers
- 40 people
- Sponsor
- Assiut University
Obstructive Pulmonary Diseases, Restrictive Lung Disease
Database of All Patients Who Have Undergone Pulmonary Function Testing at Singapore General Hospital
The purpose of this study is to create a prospective database of all patients who have undergone pulmonary function testing from which the investigators can study the clinical phenotypes of various respiratory conditions.
- Conditions
- Obstructive Pulmonary Diseases, Restrictive Lung Disease, Cough, Dyspnea
- Trial name
- NCT01601288
- Where
- Singapore
- Volunteers
- 17,000 people
- Sponsor
- Singapore General Hospital
Exercise Induced Bronchoconstriction, Asthma
Exercise Induced Bronchoconstriction and Field Tests
Asthma and exercise induced bronchoconstriction (EIB) represent an important challenge for the athlete, and correct diagnosis is important as it affects health as well as performance with strict regulations concerning asthma…
- Trial name
- EXCIT (NCT04275648)
- Testing
- AsthmaTuner exercise field test
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Karolinska Institutet
Acute Respiratory Distress Syndrome
Long Term (1 Year) Respiratory Sequelae in Children Surviving an Acute Respiratory Distress Syndrome
The purpose of this study is to assess long term (1 year) respiratory sequelae in children surviving an acute respiratory distress syndrome
- Trial name
- NCT01435889
- Where
- 5 sites in Belgium, France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Lille
Adolescent Idiopathic Scoliosis
An Aerobic Exercising Program on Respiratory Muscle Strength in Patients With Adolescent Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis (AIS) can change the respiratory dynamics and performance of the inspiratory and expiratory muscles, affecting ventilatory capacity.
- Trial name
- NCT00886652
- Testing
- Aerobic exercise program
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Irmandade da Santa Casa de Misericordia de Sao Paulo
Healthy, Pulmonary Function Test
Respiratory Oscillometry Norms for Polish Children and Adolescent.
This study aims to establish normative values for respiratory oscillometry in the Polish pediatric population. It is designed as a multicentre, population-based, prospective cohort study including children and adolescents aged…
- Trial name
- OSCILLONiCA-PL (NCT07207720)
- Where
- Poland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Primary Ciliary Dyskinesia
Chest Physiotherapy and Lung Function in Primary Ciliary Dyskinesia
Primary ciliary dyskinesia (PCD) is a rare disease, caused by impairment of the motile cilia. Patients present with chronic upper and lower respiratory tract infections.
- Trial name
- NCT01929356
- Testing
- Chest physiotherapy
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven