Clinical trials: Lung Recruitment
Pulmonary Atelectasis
Lung Ultrasound and Alveolar Recruitment in Mechanically Ventilated Infants
Investigators hypothesized that lung ultrasound-assisted recruitment maneuver would be beneficial in mechanically ventilated infants compared to those who did not receive lung ultrasound and alveolar recruitment maneuver.
- Trial name
- NCT02584023
- Testing
- Lung ultrasound
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
COVID-19, Physiotherapy
Lung Recruitment Device for COVID-19
INTRODUCTION As there is no specific cure in the treatment of COVID-19 at this moment of the pandemic, supportive management including mechanical ventilation is the core management in an intensive care unit (ICU).
- Trial name
- NCT04361435
- Testing
- Chest physiotherapy using a non-invasive oscillating device
- Volunteers
- 50 people
- Sponsor
- St. Justine's Hospital
Acute Respiratory Distress Syndrome, Acute Lung Injury
Efficacy and Safety of a Lung Recruitment Protocol in Children With Acute Lung Injury
Lung units which participate in gas exchange are known as 'recruited' lung. Patients with lung injury suffer from a proportion of units which do not participate in gas exchange (i.e.
- Trial name
- Recruitment (NCT00830284)
- Testing
- Recruitment maneuver
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Boston Children's Hospital
Collapsed Lung
Sonographic Assessment of Postural Lung Recruitment in Pediatric Patients Under General Anesthesia
Anesthesia-induced atelectasis is a well-known entity observed in approximately 68-100% of pediatric patients undergoing general anesthesia.
- Trial name
- NCT03141515
- Testing
- Lung ultrasound
- Where
- Argentina
- Volunteers
- 40 people
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Acute Respiratory Distress Syndrome
Quantitative Computed Tomography for Mortality Risk Stratification in ARDS
Acute respiratory distress syndrome remains a deadly disease with hospital mortality remaining between 40 to 50%. ARDS mortality risk factors have been identified from patient history, common clinical and biological variables in…
- Trial name
- CT4ARDS-2 (NCT06113276)
- Testing
- Low dose computed tomography to evaluate biomechanical parameters in the lung
- Where
- 4 sites in France
- Volunteers
- 210 people
- Sponsor
- Hospices Civils de Lyon
Bronchopulmonary Dysplasia
The Impact of Lung Recruitment Maneuver in 24-32 Weekers, and the Incidence of Bronchopulmonary Dysplasia
hypothesis : 1. The incident of dysplasia bronchopulmonary and/or death in 24-32 weekers babies on assist-control volume guarantee ventilation are lower in lung recruitment maneuver (LRM) group compare to control. 2.
- Trial name
- NCT04555889
- Testing
- lung recruitment maneuver (LRM) with DrageerVN500
- Volunteers
- 110 people
- Sponsor
- Dr. R. Adhi Teguh Perma Iskandar, Sp.A(K)
Acute Respiratory Distress Syndrome
Open Lung Ventilation in ARDS: The PHARLAP Trial
Some people develop the condition called acute respiratory distress syndrome (ARDS). This is a condition where the lungs have become injured from one of a number of various causes, and do not work as they normally do to provide…
- Trial name
- PHARLAP (NCT01667146)
- Testing
- PHARLAP mechanical ventilation strategy, Control group mechanical ventilation strategy
- Where
- 27 sites in Australia, Ireland and 3 more
- Volunteers
- 115 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Respiratory Distress Syndrome in Premature Infant
Pressure HIgh or LOw DElivered to Preterm Newborns in the Delivery ROOM
The aim of this randomized pilot clinical trial of preterm infants requiring noninvasive respiratory support for respiratory distress syndrome (RDS) at birth is to improve short-term respiratory outcomes.
- Trial name
- PHILODENDROOM (NCT06123845)
- Testing
- static CPAP 8 cmH2O, static CPAP 5 cmH2O
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- ASST Fatebenefratelli Sacco
Asthma
Registry of Asthma Characterization and Recruitment 3 (RACR3)
This is a multi-center, non-interventional registry to create and maintain a database of participants to serve as a recruitment source for current and future DAIT NIAID-sponsored Childhood Asthma in Urban Settings (CAUSE) studies.
- Trial name
- RACR3 (NCT05272241)
- Where
- 7 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pulmonary Atelectasis, Postoperative, Atelectasis, Compression
Postoperative Atelectasis in Pediatric Patients With Prone Position
This study evaluates the incidence of postoperative atelectasis after general anesthesia with prone position using lung ultrasound in children age < 3 years.
- Trial name
- NCT03486847
- Testing
- Repetitive recruitment with PEEP, One recruitment with PEEP
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Seoul National University Hospital
Breast Carcinoma, Colon Carcinoma
Social Media Listening in Improving Clinical Trial Recruitment in Patients With Cancer
This pilot clinical trial studies how well social media listening works in improving clinical trial recruitment in patients with cancer.
- Conditions
- Breast Carcinoma, Colon Carcinoma, Kidney Carcinoma, Lymphoma
- Trial name
- NCT03408561
- Testing
- Internet-Based Intervention, Survey Administration
- Where
- United States
- Sponsor
- University of Southern California
Prostate Cancer, Lung Protective Ventilation
Evaluating Respiratory Effects of Driving Pressure Guided Mechanical Ventilation Using Electrical Impedance Tomography in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Robot-Assisted Laparoscopic Radical Prostatectomy is a method increasingly used for prostate cancer due to fewer complications, morbidity, and mortality compared to other methods.
- Conditions
- Prostate Cancer, Lung Protective Ventilation, Postoperative Pulmonary Complications
- Trial name
- NCT06540794
- Testing
- PEEP TITRATION
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University
Atelectasis
Lung Recruitment Assessment With Lung Ultrasound In Pediatric Patient Scheduled For Laparoscopic Surgery
Anesthesia-induced atelectasis is a well-known entity observed in approximately 68-100% of pediatric patients undergoing general anesthesia.
- Trial name
- NCT02824146
- Testing
- Lung recruitment maneuver
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Bronchopulmonary Dysplasia, Chronic Pulmonary Insufficiency of Prematurity
Late Surfactant After a Recruitment Maneuver in Extremely Low Gestational Age Newborns - LATE-REC-SURF Trial
This is an unblinded monocentric pilot superiority trial that will be conducted in a IIIlevel NICU at Fondazione Policlinico Agostino Gemelli - IRCCS.
- Trial name
- LateRecSurf (NCT04825197)
- Testing
- Poractant Alfa Intratracheal Suspension [Curosurf]
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- VENTO GIOVANNI
Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes
Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)
This multicenter cross-sectional study will include a diverse population of adolescents and adults with CF. The overall Aim is to describe prevalence of diabetes microvascular complications and macrovascular surrogates in people…
- Conditions
- Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes, Diabetes, Retinopathy
- Trial name
- SPeCTRuM (NCT06837181)
- Testing
- observational study
- Where
- 18 sites in United States
- Volunteers
- 200 people
- Sponsor
- Jaeb Center for Health Research
Postoperative Pulmonary Complications, Postoperative Pulmonary Atelectasis
Evaluation of the Effect of Perioperative Recruitment Maneuver Practice on Lung Ultrasound Score and Mechanical Power in Pediatric Patients
Pulmonary atelectasis is common during general anesthesia and increases the risk of hypoxemia, especially in pediatric patients. PEEP and recruitment maneuvers (RM) are effective in preventing atelectasis.
- Conditions
- Postoperative Pulmonary Complications, Postoperative Pulmonary Atelectasis, Pediatric Surgery
- Trial name
- LUS RM PEEP (NCT07294560)
- Testing
- recruitment maneuver, right and left lateral decubitus position recruitment maneuvers
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Istanbul University - Cerrahpasa
Acute Respiratory Distress Syndrome
EIT- Guided Lung Recruitment in pARDS
Study Title: EIT-Guided Lung Recruitment Maneuvers in Pediatric ARDS: Effects on Ventilation Distribution and Respiratory Mechanics Study Objective: The primary goal of this clinical trial is to determine whether lung recruitment…
- Trial name
- REMAV-EIT (NCT07402174)
- Testing
- Electrical Impedance Tomography (EIT)-Guided Lung Recruitment
- Where
- 2 sites in Italy
- Volunteers
- 8 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Anesthesia, Intravenous Fluid
Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients
In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration.
- Conditions
- Anesthesia, Intravenous Fluid, Blood Pressure
- Trial name
- NCT03431064
- Testing
- Lung Recruitment Maneuver, Fluid Administration
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Boston Children's Hospital
Hypovolemia
Lung Recruitment Maneuver for Predicting Fluid Responsiveness in Children
Lung recruitment maneuver induces a decrease in stroke volume, which is more pronounced in hypovolemic patients. The authors hypothesized that the changes of dynamic variables through lung recruitment maneuver could predict…
- Trial name
- NCT03184961
- Testing
- lung recruitment maneuver
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Asthma
Registry for Asthma Characterization and Recruitment 2
There is a need for people to take part in research studies to learn more about diseases and how to treat them. The Registry for Asthma Characterization and Recruitment 2 (RACR2) will create a database of participants with asthma…
- Trial name
- RACR2 (NCT02513264)
- Where
- 10 sites in United States
- Volunteers
- 1,384 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)