Clinical trials: Lymph Node
Breast Cancer
Comparison of Complete Axillary Lymph Node Dissection With Axillary Radiation Therapy in Treating Women With Invasive Breast Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells and may be a less invasive treatment and cause fewer side effects than complete axillary lymph node dissection.
- Trial name
- AMAROS (NCT00014612)
- Testing
- axillary lymph node dissection, lymphoscintigraphy, therapeutic conventional surgery
- Where
- 29 sites in France, Italy and 6 more
- Volunteers
- 4,813 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Mucocutaneous Lymph Node Syndrome
Methylprednisolone Pulse Therapy for Coronary Artery Dilatation or Aneurysm Formation in Kawasaki Disease
In this study, the investigator plan to prescribe Methylprednisolone pulse therapy in Kawasaki disease patients with coronary artery lesions or aneurysm formation beyond acute stage to investigate the role for vasculitis of KD or…
- Trial name
- NCT04509219
- Testing
- Methylprednisolone Injection
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Chang Gung Memorial Hospital
Allergic Rhinitis
Safety of Lymph Node Injection for Allergen Immunotherapy
The purpose of this study is to determine safety of allergy immunotherapy lymph node injections for grass pollen allergies.
- Trial name
- NCT01982474
- Testing
- Grass pollen extract
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Amber Patterson
Breast Neoplasms
Robotic-Assisted Versus Endoscopic-Assisted Axillary Lymph Node Dissection in Breast Cancer
This is a multicenter, retrospective observational study comparing the safety and efficacy of robotic-assisted versus endoscopic-assisted axillary lymph node dissection (ALND) in patients with node-positive breast cancer.
- Trial name
- NCT07693361
- Where
- 2 sites in China
- Volunteers
- 127 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Endometrial Carcinoma, Lymphadenectomy
The Clinical Significance of Sentinel Lymph Node Imaging Combined With Imaging Examination in Pelvic and Peritoneal Lymphadenectomy for Endometrial Carcinoma
The aim of this prospective cohort study is to explore the clinical significance of sentinel lymph node imaging combined imaging examination evaluation in pelvic and peritoneal lymphadenectomy for endometrial carcinoma management.
- Trial name
- NCT03877627
- Testing
- Pelvic and Peritoneal Lymphadenectomy
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Kawasaki Disease
Kawasaki Disease During the COVID-19 Epidemic
Northern Italy is the second region hit by the SARS-COV2 infection worldwide. Data on COVID-19 clinical presentation in children is still scarce, but fewer rate of infection and milder disease seem typical of this age group.
- Trial name
- KAWACOVID (NCT06309303)
- Testing
- Clinical evaluation
- Where
- 4 sites in Italy
- Volunteers
- 25 people
- Sponsor
- IRCCS Burlo Garofolo
Kawasaki Disease, Coronary Aneurysm
Doxycycline Treatment to Prevent Progressive Coronary Artery Dilation in Children With Kawasaki Disease
Kawasaki disease (KD) affects infants and young children causing inflammation of the skin and blood vessels including the coronary arteries of the heart.
- Trial name
- NCT01917721
- Testing
- Doxycycline
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Hawaii Pacific Health
Lung Cancer
Molecular Assessment of Lymph Nodes in Patients With Resected (Stage I to IIIA) Non-small Cell Lung Cancer
This is a prospective study of surgically resected samples and lymph nodes of lung cancer patients. For histopathologically positive lymph nodes from a complete resection, the investigators would like to analyse tumor tissue by…
- Trial name
- NCT00213733
- Where
- 5 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
Breast Cancer
Sentinel Lymph Node Mapping With Near Infrared Fluorescent Markers
Surgery is the primary curative option for patients with cancer, with the overall objective of complete resection of all cancerous tissue while avoiding damage to healthy tissue.
- Trial name
- NCT03619967
- Testing
- Multispectral imager
- Where
- North Macedonia
- Volunteers
- 31 people
- Sponsor
- University of Illinois at Urbana-Champaign
Invasive Breast Cancer
Computed Tomography (CT) Reconstruction for Axillary Lymph Node Structure
This is a prospective, single-center, non-randomized, non-controlled observational study.
- Trial name
- CTREP (NCT03247478)
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Peking University
Melanoma
Melanoma Molecular Profiling Analysis
There is a significant need to develop new and more effective ways to treat melanoma that will decrease patient morbidity and mortality.
- Trial name
- NCT00889980
- Testing
- Biospecimen banking
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- University of Pittsburgh
Kawasaki Disease, Atypical Kawasaki Disease
Genetic Determinants of Kawasaki Disease
Kawasaki disease (KD) is an acute self-limited vasculitis of infancy and early childhood. Most patients recover without sequelae although the inflammatory process causes permanent damage to the coronary arteries in 20-25% of…
- Trial name
- NCT03861130
- Where
- United Kingdom
- Volunteers
- 1,379 people
- Sponsor
- Imperial College London
Cancer
OX-40 Protein Expression in the Sentinel Lymph Nodes of Patients With Cancer
RATIONALE: Studying protein expression in sentinel lymph node tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
- Trial name
- NCT00900302
- Testing
- protein expression analysis, immunohistochemistry staining method, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- OHSU Knight Cancer Institute
Benign and Malignant Lymph Nodes
Ultrasound Imaging Based on Ultrasound Bronchoscopy in Respiratory Diseases: a Retrospective, Single-center, Confirmatory Study
ABSTRACT Background and objective: To establish a ultrasound radiomics machine learning model based on endobronchial ultrasound (EBUS)to assistdoctors in distinguishing between benign and malignant diagnoses ofmediastinal and…
- Trial name
- NCT06351319
- Testing
- SVM model
- Where
- China
- Volunteers
- 197 people
- Sponsor
- Quncheng Zhang
Colorectal Cancer
Endoscopic Versus Surgical Treatment for T1 Colorectal Cancer
The implementation of population screening programs for colorectal cancer (CRC) has led to a considerable increase in the prevalence T1 CRC originating on polyps amenable by endoscopy.
- Trial name
- EpiT1 (NCT04150081)
- Testing
- Surgery or Endoscopic treatment
- Where
- Spain
- Volunteers
- 1,400 people
- Sponsor
- Hospital Clinic of Barcelona
Kawasaki Disease
Clinical Precise Diagnosis and Treatment in the Kawasaki Disease
The purpose of this project is to explore the differential gene expression profile of Kawasaki disease, and will explore the diagnosis and treatment targets related to coronary artery injury or kawasaki disease susceptibility…
- Trial name
- NCT05347901
- Testing
- Echocardiography, Genomics NGS sequencing
- Where
- 4 sites in China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Nantong University
Thyroid Cancer, Papillary
Intraoperative Pathologic Evaluation of Central Lymph Nodes in Papillary Thyroid Carcinoma
Efficacy of Intraoperative pathologic evaluation of central lymph nodes
- Trial name
- NCT07066644
- Testing
- central node dissection
- Where
- South Korea
- Volunteers
- 509 people
- Sponsor
- Seoul National University Hospital
Kawasaki Disease
Pilot Study of Atorvastatin and Anakinra in Children With Coronary Artery Abnormalities Secondary to Kawasaki Disease
Kawasaki disease (KD) is the leading cause of acquired heart disease in children in the developed world. Despite available treatment, 25% of children in San Diego County appropriately treated for KD develop coronary artery…
- Trial name
- NCT04747847
- Testing
- Atorvastatin and anakinra
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of California, San Diego
Lymph Node Disease, Ultrasound Therapy; Complications
Identifying Ultrasonic Diagnostic Characteristics of Cervical Lymphadenopathy: A Retrospective, Multicenter Study
The observed indexes of the four cervical lymph node diseases were identified by informatics methods, and the differences in the diagnosis of the four diseases were evaluated, so as to improve the clinical diagnosis rate and…
- Trial name
- NCT04497714
- Testing
- Ultrasonic image collection
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Kawasaki Disease
Efficacy of Immunoglobulin Plus Prednisolone in Reducing Coronary Artery Lesion in Patients With Kawasaki Disease
This study evaluates the efficacy of the addition of prednisolone to conventional initial treatment (intravenous immunoglobulin [IVIG] plus aspirin) in reducing coronary artery lesion in children with Kawasaki disease (KD) .
- Trial name
- NCT04078568
- Testing
- IVIG, Aspirin, Prednisolone
- Where
- 34 sites in China
- Volunteers
- 3,208 people
- Sponsor
- Children's Hospital of Fudan University