Clinical trials: Lymph Node Disease
Adenocarcinoma of the Prostate
Intensity Modulated Radiation Therapy (IMRT) Pelvic Nodes Prostate
The purpose of this study is to determine the feasibility and late toxicity of dose escalated radiation therapy to the pelvic lymph nodes and prostate and seminal vesicles in the treatment of high risk prostate cancer.
- Trial name
- NCT00915122
- Testing
- Dose Escalated IMRT
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- University Health Network, Toronto
Melanoma
Melanoma Molecular Profiling Analysis
There is a significant need to develop new and more effective ways to treat melanoma that will decrease patient morbidity and mortality.
- Trial name
- NCT00889980
- Testing
- Biospecimen banking
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- University of Pittsburgh
Sentinel Lymph Node, Early Gastric Cancer
Feasibility Study of Sentinel Navigation Surgery After Non-curative Endoscopic Resection
Purpose: To prove the feasibility of sentinel node navigation surgery (SNNS) in early gastric cancer patients with the risk of lymph node metastasis after endoscopic resection and preparation of multicenter phase 3 trial of…
- Trial name
- SENORITA2 (NCT03123042)
- Testing
- Sentinel basin dissection
- Where
- 9 sites in South Korea
- Volunteers
- 243 people
- Sponsor
- National Cancer Center, Korea
Kawasaki Disease, Inflammation
Characterization of Multisystem Inflammatory Syndrome in Children (MIS-C) and Its Relationship to Kawasaki Disease
Beginning in mid-March 2020, pediatricians in communities in Western Europe, the UK, and the Eastern U.S. that had been severely affected by the Covid-19 pandemic noted an increased number of children presenting with fever and…
- Trial name
- NCT04538495
- Where
- United States
- Volunteers
- 268 people
- Sponsor
- University of California, San Diego
Lymph Node Metastases
Lymph Node Metastases and Arterial Ligation in Rectal Cancer Surgery
Lymph node status is of major prognostic importance in non-metastatic rectal cancer. For oncological reasons, central arterial ligation of the inferior mesenteric artery (IMA) is suggested.
- Trial name
- NCT03314961
- Volunteers
- 151 people
- Sponsor
- Region Västmanland
Breast Cancer
Positive Node Traced Before Neoadjuvant Chemotherapy (NAC)
To investigate this regression model by injecting and tracing carbon nanoparticles (CNs) into the fusion node prior to NAC in patients with breast cancer.
- Trial name
- NCT03355261
- Testing
- complete remission (CR) group, partial remission (PR) group, stable disease (SD) group
- Where
- 3 sites in China
- Volunteers
- 110 people
- Sponsor
- Shengjing Hospital
Papillary Thyroid Cancer, Lymph Node Metastases
Evaluation of Accuracy of One-Step Nucleic Acid Amplification (OSNA) in Diagnosis of Lymph Node Metastases of Papillary Thyroid Carcinoma
The incidence of node metastases in papillary thyroid carcinoma (PTC) is high, ranging from 20% to 90%. Prophylactic central lymph node compartment dissection (CLND), suggested from the latest guidelines for high-risk tumors…
- Trial name
- NCT03889769
- Testing
- OSNA test
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Cagliari
Kawasaki Disease, Steroid
A Trial to Evaluate the Efficacy of Immunoglobulin Plus Steroid for Prevention of Coronary Artery Abnormalities in Taiwanese Refractory Kawasaki Disease (RAST Study)
Background: Kawasaki disease (KD), most popular acquired heart disease in childhood, is characterized by diffuse vasculitis, especially on the middle-sized muscular arteries. IVIG and aspirin are currently standard treatment.
- Conditions
- Kawasaki Disease, Steroid, Immuoglobulin
- Trial name
- RAST (NCT03200561)
- Testing
- Prednisolone, immunoglobulin
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Rectum Cancer
A Lymph Node Metastasis Predictor (LN-MASTER) in Rectal Cancer
In this study, we aim to develop and validate an easy-to-use machine learning prediction model to preoperatively identify the lymph node metastasis status for rectal cancer patients by using these clinical data from three…
- Trial name
- NCT05493930
- Testing
- The hospital where the treatment is performed
- Volunteers
- 6,578 people
- Sponsor
- Peking Union Medical College
Deep Learning Model
Deep Learning Model for Diagnosis and Contour of Cervical Lymph Node for Nasopharyngeal Carcinoma
The diagnosis of cervical lymph node in nasopharyngeal carcinoma is difficult. Magnetic resonance imaging based deep learning model may be a noninvasive and rapid diagnostic method for cervical lymph node.
- Trial name
- NCT05231616
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Sun Yat-sen University
Kawasaki Disease, Coronary Aneurysm
Doxycycline Treatment to Prevent Progressive Coronary Artery Dilation in Children With Kawasaki Disease
Kawasaki disease (KD) affects infants and young children causing inflammation of the skin and blood vessels including the coronary arteries of the heart.
- Trial name
- NCT01917721
- Testing
- Doxycycline
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Hawaii Pacific Health
Kawasaki Disease, Coronary Artery Abnormalities
Statins Study in Kawasaki Disease Children With Coronary Artery Abnormalities
The aim of this study is to investigate the effects of statins on chronic inflammation, coronary artery abnormalities and clinical cardiac events in long-term KD children complicated with severe coronary artery abnormalities, and…
- Trial name
- NCT03915795
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Children's Hospital of Fudan University
Pancreatic Neoplasms, Pancreatic Adenocarcinoma
The Prognostic Impact of Extracapsular Lymph Node Involvement in Ductal Pancreatic Adenocarcinoma
Extracapsular lymph node involvement (ECLNI) has been identified as a pathological variable associated with worse outcome in esophageal, gastric and colorectal cancer.
- Trial name
- ECLNI DPAC (NCT00644254)
- Testing
- Pancreatic resection
- Where
- Belgium
- Volunteers
- 145 people
- Sponsor
- KU Leuven
Thyroid Papillary Carcinoma
Prospective Study on the Clinical Prognosis of Bilateral Central Lymph Node Dissection in the Patients With Unilateral Thyroid Papillary Carcinoma
This study recruit the patients with unilateral papillary thyroid cancer before operation,the patients agree to enter the test,and divided into experimental and control group.experimental group patients receive the surgery…
- Trial name
- NCT02648399
- Testing
- surgery：BCND（bilateral central lymph node dissection）, surgery：UCND（unilateral central lymph node dissection）
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Fujian Medical University
Sentinel Lymph Node, Breast Cancer
Application of Surgical Navigation System in Sentinel Lymph Node of Breast Cancer Research
The purpose of this study is to compare the sentinel lymph node (SLN) detection rate of early breast cancer patients between using Indocyanine green (ICG) and Methylene blue with a novel surgical navigation system.
- Trial name
- NCT02084784
- Testing
- Indocyanine green, methylene blue
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Chinese Academy of Sciences
Melanoma, Skin Cancer
Interferon Alfa With or Without Combination Chemotherapy Plus Interleukin-2 in Treating Patients With Melanoma
RATIONALE: Interferon alfa may interfere with the growth of cancer cells. Interleukin-2 may stimulate a person's white blood cells to kill melanoma cells.
- Trial name
- NCT00002882
- Testing
- Aldesleukin (IL-2), Recombinant Interferon Alfa (IFN-A), Cisplatin
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- M.D. Anderson Cancer Center