Clinical trials: Lymph Node Neoplasm
Gastric Neoplasm
Randomized Controlled Trial to Evaluate Surgical Approaches to Gastric Cancer Invading the Esophagus (JCOG9502)
To compare left thoraco-abdominal approach with abdominal and transhiatal approach to cardia or subcardia cancer
- Trial name
- NCT00149266
- Testing
- Surgery: abdominal and transhiatal approach, Surgery: left thoraco-abdominal approach
- Where
- Japan
- Volunteers
- 167 people
- Sponsor
- Japan Clinical Oncology Group
Melanoma
Melanoma Molecular Profiling Analysis
There is a significant need to develop new and more effective ways to treat melanoma that will decrease patient morbidity and mortality.
- Trial name
- NCT00889980
- Testing
- Biospecimen banking
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- University of Pittsburgh
Endometrial Cancer
Biomarkers in Tissue Samples From Patients With Stage I or Stage III Endometrial Cancer
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
- Trial name
- NCT01119573
- Testing
- RNA analysis, microarray analysis, reverse transcriptase-polymerase chain reaction
- Volunteers
- 100 people
- Sponsor
- Gynecologic Oncology Group
Gastric Cancer Stage, Lymph Node Metastasis
Association Between Multiple Coagulation-related Factors and Lymph Node Metastasis in Patients With Gastric Cancer: A Retrospective Cohort Study
We initially selected a total of 1128 patients with primary gastric cancer who presented at Shandong Provincial Hospital between January 2018 and October 2022, and retrospectively collected their clinical and pathological data.
- Trial name
- MA (NCT05592925)
- Testing
- coagulation-related factors
- Where
- China
- Volunteers
- 516 people
- Sponsor
- Shandong Provincial Hospital
Pancreatic Adenocarcinoma, Lymph Node Metastasis
EUS Role in Non-metastatic Pancreatic Adenocarcinoma Lymph Nodes Staging
Aim of the study will be to investigate if Endoscopic Ultrasound (EUS) with elastography can be purposed between the routine staging examinations in patients with pancreatic adenocarcinoma without distant metastasis for the…
- Trial name
- NCT06341725
- Testing
- malignant lymph nodes
- Where
- Italy
- Volunteers
- 2 people
- Sponsor
- Paolo Giorgio Arcidiacono, MD
Thyroid Cancer, Papillary
Intraoperative Pathologic Evaluation of Central Lymph Nodes in Papillary Thyroid Carcinoma
Efficacy of Intraoperative pathologic evaluation of central lymph nodes
- Trial name
- NCT07066644
- Testing
- central node dissection
- Where
- South Korea
- Volunteers
- 509 people
- Sponsor
- Seoul National University Hospital
Gastric Neoplasm
A Trial to Evaluate Para-aortic Lymphadenectomy for Gastric Cancer
To evaluate the survival benefit of para-aortic lymphadenectomy in potentially curative gastrectomy
- Trial name
- NCT00149279
- Testing
- Surgery: D2 dissection, Surgery: D2+paraaortic dissection
- Where
- Japan
- Volunteers
- 520 people
- Sponsor
- Japan Clinical Oncology Group
Early Stage Breast Carcinoma
Sentinel Node Vs Observation After Axillary Ultra-souND
The hypothesis of this trial are that: avoiding axillary surgery does not worsen the outcome of patients with small breast cancer the absence of the pathological information on the risk of recurrence given by nodal status is not…
- Trial name
- SOUND (NCT02167490)
- Testing
- Arm 1: sentinel node biopsy
- Where
- 18 sites in Chile, Italy and 2 more
- Volunteers
- 1,560 people
- Sponsor
- European Institute of Oncology
Melanoma
Intraoperative Mapping of Regional Lymphatics Draining the Primary Site of Melanoma Using Isosulfan Blue
The purpose of this study is to determine whether we can consistently identify the first lymph node (the "sentinel node") draining your melanoma.
- Trial name
- NCT00581698
- Where
- United States
- Volunteers
- 876 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
Application of Rapid On-site Evaluation in Lymph Node Biopsy of Breast Cancer
The goal of this clinical trial is to evaluate the value of rapid on-site evaluation（ROSE） in lymph node biopsy of breast cancer.
- Trial name
- NCT06495736
- Testing
- Experimental: ROSE technique stain
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Yunnan Cancer Hospital
Early Gastric Cancer
Endoscopic Submucosal Dissection Combine With Laparoscopic Regional Lymph Node Dissection for Early Gastric Cancer
The purpose of this study is to determine whether Endoscopic Submucosal Dissection combine with Laparoscopic Regional Lymph node Dissection for early gastric cancer can improve Disease-free survival ？
- Trial name
- NCT02325999
- Testing
- ESD AND LRLD
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Friendship Hospital
Prostate Cancer
Choline PET/CT vs. MeAIB PET/CT in Prostate Cancer
Prostate cancer is currently the leading newly diagnosed cancer in the industrialized world. Treatment of prostate cancer is highly dependent on the stage of the disease.
- Trial name
- NCT02232672
- Testing
- Choline PET/CT and MeAIB PET/CT
- Where
- Denmark
- Sponsor
- Odense University Hospital
Colorectal Cancer
Endoscopic Versus Surgical Treatment for T1 Colorectal Cancer
The implementation of population screening programs for colorectal cancer (CRC) has led to a considerable increase in the prevalence T1 CRC originating on polyps amenable by endoscopy.
- Trial name
- EpiT1 (NCT04150081)
- Testing
- Surgery or Endoscopic treatment
- Where
- Spain
- Volunteers
- 1,400 people
- Sponsor
- Hospital Clinic of Barcelona
Lung Adenocarcinoma
Lymph Node Pathologic Grading Strategy
The percentage of high-grade patterns in metastatic LNs (mLNs) that can predict poor outcomes has yet to be determined. Additionally, the potential implications of other histologic patterns in metastatic lymph nodes on patient…
- Trial name
- NCT06745830
- Testing
- No intervention
- Where
- China
- Volunteers
- 2,998 people
- Sponsor
- Fudan University
Rhabdomyosarcoma, Melanoma
A Study of Lymphoseek® as a Lymphoid Tissue Targeting Agent in Pediatric Patients With Melanoma, Rhabdomyosarcoma, or Other Solid Tumors Who Are Undergoing Lymph Node Mapping
Open label, non-randomized, multi-center, within-subject comparative study to evaluate the tolerability and the diagnostic utility of Lymphoseek with optional comparison to VBD in pediatric subjects with melanoma…
- Trial name
- NCT02509598
- Testing
- Tc99m tilmanocept, Vital Blue Dye (optional), Lymph Node Mapping
- Where
- 6 sites in United States
- Volunteers
- 24 people
- Sponsor
- Cardinal Health 414, LLC
Acute Myeloid Leukemia, Acute Lymphoid Leukemia
Irradiation-based Myeloablative Conditioning Followed by Treg/Tcon Immunotherapy in HSCT
To evaluate if hyper-fractionated TBI or TMLI followed by Treg/Tcon adoptive immunotherapy improve cGvHD/disease free survival after allogeneic HSCT in patients affected by high-risk acute leukemias or other hematologic…
- Conditions
- Acute Myeloid Leukemia, Acute Lymphoid Leukemia, Myeloproliferative Disorders, Lymphoma
- Trial name
- NCT03977103
- Testing
- High dose irradiation conditioning + Treg/Tcon
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University Of Perugia
Breast Cancer, Sentinel Lymph Node
Sentinel Lymph Node Biopsy in Early Breast Cancer: a Real-world Multicenter Cross-sectional Study (CABS001 Study)
Objective: To investigate the current clinical practice of sentinel lymph node biopsy (SLNB) in patients with early stage breast cancer in China.
- Trial name
- NCT04156841
- Testing
- mapping agent, neoadjuvant chemotherapy
- Where
- China
- Volunteers
- 21,000 people
- Sponsor
- Xijing Hospital
Breast Cancer
Hormone Therapy in Treating Postmenopausal Women With Receptor-Positive Breast Cancer
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using tamoxifen may fight breast cancer by blocking the uptake of estrogen.
- Trial name
- NCT00002646
- Testing
- fenretinide, tamoxifen citrate
- Where
- 85 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Eastern Cooperative Oncology Group
Sentinel Lymph Node, Breast Cancer
Application of Surgical Navigation System in Sentinel Lymph Node of Breast Cancer Research
The purpose of this study is to compare the sentinel lymph node (SLN) detection rate of early breast cancer patients between using Indocyanine green (ICG) and Methylene blue with a novel surgical navigation system.
- Trial name
- NCT02084784
- Testing
- Indocyanine green, methylene blue
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Chinese Academy of Sciences
Lymph Node Dissection
Prognostic Value of Lymph Node Dissection in Patients With Transitional Cell Carcinoma of the Upper Urinary Tract
Recent studies showed the therapeutic benefit of lymphadenectomy in advanced stage urothelial carcinoma of the upper urinary tract, but there is still a lack of prospective studies.
- Trial name
- NCT03474926
- Testing
- Routine Template-based lymphadenectomy, LND only for lymph nodes enlargement found in preoperative image or during surgery
- Where
- 2 sites in China
- Volunteers
- 504 people
- Sponsor
- RenJi Hospital