Clinical trials: Malabsorption
Coeliac Disease
Interest of Urinary Measurement of Immunogenic Gluten Peptides (GIP) in the Follow-up of Pediatric Celiac Patients.
The main reason for insufficient control of celiac disease is non-adherence to the gluten-free diet (GFD), whether voluntary or involuntary. In children, involuntary exposures are common (canteens, snacks, restaurants).
- Trial name
- GIped (NCT07578038)
- Testing
- Urinary measurement of GIP, Usual follow-up and measurement of urinary GIP.
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Lenval
Cholestasis
Use of Omega 3 Oil Emulsion for Parenteral Nutrition Associated Cholestasis
This is a clinical study designed to evaluate the safety and benefit of a fish oil based fat emulsion in the treatment of liver disease associated with prolonged use of intravenous nutrition.
- Trial name
- NCT02148146
- Testing
- Omegaven
- Where
- 2 sites in United States
- Sponsor
- University of California, San Diego
Celiac Disease
Treatment of Mild Enteropathy Celiac Disease
The main purpose of this study is to evaluate the natural history of gluten sensitivity in endomysial antibody positive adults with celiac disease suspicion, who were found to have a only mild enteropathy (Marsh I-II) in the…
- Trial name
- TMCD (NCT00628823)
- Testing
- Gluten-free diet
- Where
- Finland
- Volunteers
- 73 people
- Sponsor
- Tampere University Hospital
Cow's Milk Protein Allergy, Eosinophilic Gastrointestinal Disorders
A Study to Monitor the Use of an Amino Acid-Based Infant Formula
To assess the frequency and nature of adverse events in infants fed a free amino acid based infant formula.
- Conditions
- Cow's Milk Protein Allergy, Eosinophilic Gastrointestinal Disorders, Malabsorption/Maldigestion, Short Bowel Syndrome
- Trial name
- EAGLE (NCT02953223)
- Testing
- Free amino acid infant formula
- Where
- 29 sites in United States
- Volunteers
- 144 people
- Sponsor
- Société des Produits Nestlé (SPN)
Iron Deficiency Anemia of Pregnancy, Iron Malabsorption
Intravenous Iron for Iron-deficiency Anemia in Pregnancy: a Randomized Controlled Trial
Iron deficiency is the most common cause of anemia in pregnancy worldwide, and, when severe, can have serious consequences for mothers and babies.
- Trial name
- IVIDA (NCT03438227)
- Testing
- Iron dextran, Ferrous sulfate 325mg
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- Indiana University
Total Parenteral Nutrition-induced Cholestasis, Cholestasis
Compassionate Use of Omegaven in Children
This is a single-assignment study to evaluate whether Omegaven (IV fish oil) is effective at treating liver disease in children on long-term IV nutrition.
- Conditions
- Total Parenteral Nutrition-induced Cholestasis, Cholestasis, Short Bowel Syndrome, Gastroschisis
- Trial name
- NCT02370251
- Testing
- Omegaven
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Oklahoma
Short Bowel Syndrome
Effect of a Short Message Service Intervention on Patients With Short Bowel Syndrome
The investigators will be using a text messaging intervention to identify potentially dangerous and re- admission causing symptoms in patients with Short Bowel Syndrome (SBS) on Total Parenteral Nutrition (TPN).
- Trial name
- NCT03419156
- Testing
- Text Message Arm Intervention
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- St. Louis University
Short Bowel Syndrome
Long-term Study of Teduglutide in Pediatric Subjects With Short Bowel Syndrome Who Completed the TED-C13-003 Study
The purpose of this study is to evaluate the safety and efficacy of teduglutide treatment of children with short bowel syndrome (SBS) who completed the TED-C13-003 study over a long-term period.
- Trial name
- NCT02949362
- Testing
- Teduglutide, SOC
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 29 people
- Sponsor
- Shire
Cystic Fibrosis, Pancreatic Insufficiency
Evaluation of the Safety and Efficacy of Pancrecarb® MS-16 in Cystic Fibrosis
The primary objective of this study is to determine if PANCRECARB® MS-16 (pancrelipase) is safe and effective in reducing steatorrhea (as measured by 72-hour stool fat determinations) in children and adults with cystic fibrosis…
- Trial name
- NCT00432861
- Testing
- PANCRECARB® (pancrelipase)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Digestive Care, Inc.
Exocrine Pancreatic Insufficiency, Cystic Fibrosis
Control of Steatorrhea in Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency
This study by Aptalis (formerly Axcan) assesses the efficacy and safety of Panzytrat® 25,000 compared to Kreon® 25,000 in the control of steatorrhea in participants with cystic fibrosis (CF) and exocrine pancreatic insufficiency…
- Trial name
- NCT01327703
- Testing
- Panzytrat® 25,000, Kreon® 25,000
- Where
- 13 sites in Germany, Poland
- Volunteers
- 87 people
- Sponsor
- Forest Laboratories
Celiac Disease in Children
"Adding DNA-test for Screening of HLA-DQ2 and DQ8 to Improve Early Diagnosis of Celiac Disease"
Celiac Disease (CD) is an immune-mediated systemic disorder elicited by the ingestion of gluten containing cereals from the normal diet, among others wheat, rye and barley.
- Trial name
- GLUTEN-GEN (NCT06179121)
- Testing
- DNA test for screening HLA-DQ2 and DQ8 from dried blood spots to early detect Celiac Disease
- Where
- Netherlands
- Volunteers
- 508 people
- Sponsor
- Leiden University Medical Center
Short Bowel Syndrome, Necrotizing Enterocolitis
Early Provision of Enteral Microlipid and Fish Oil to Infants With Enterostomy
Necrotizing enterocolitis (NEC) and intestinal perforation are common in premature infants. Often surgery is needed to remove the dead bowel and create an ostomy (a temporary intestinal opening on the infant's abdomen).
- Conditions
- Short Bowel Syndrome, Necrotizing Enterocolitis, Small Intestine Perforation
- Trial name
- EMLFO (NCT01306838)
- Testing
- MicroLipid and fish oil, Routine care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wake Forest University
Celiac Disease
Virtual Celiac Symptoms Study in Adults and Teenagers
The goal of this study is to better understand the symptoms and impacts of celiac disease (CeD). Participants use a smart phone online app to answer daily questionnaires about symptoms and life with CeD for 12 weeks.
- Trial name
- NCT05309330
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 480 people
- Sponsor
- Takeda
Celiac Disease, Celiac Disease in Children
Celiac Disease in Childhood-Adulthood Transition
Aims of this study are to evaluate adolescents with celiac disease during their transition from pediatrics to adult care, and to develop better healthcare follow-up practices.
- Conditions
- Celiac Disease, Celiac Disease in Children, Transition of Care, Follow-up
- Trial name
- CeliCAT (NCT05084937)
- Testing
- CeliCAT form
- Where
- 5 sites in Finland
- Volunteers
- 400 people
- Sponsor
- Tampere University Hospital
Short Bowel Syndrome
Evaluation of the Efficacy and Safety of Recombinant Human Growth Hormone (rhGH) in the Treatment of Children With Short Bowel Syndrome
This is a randomized controlled, parallel group, open label versus "no treatment" trial which evaluate the efficacy of rhGH on weaning off parenteral nutrition in children with short bowel syndrome.The total follow-up is 14…
- Trial name
- NCT00169637
- Testing
- rhGH
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Hospices Civils de Lyon
Celiac Disease in Children, Gluten Enteropathy
Influence of a Gluten Free Food Guide on Diet Quality and Adherence to the GFD in Youth With Celiac Disease
Celiac disease (CD) is an autoimmune gastrointestinal disease that is caused by intolerance to gluten in the diet. The mainstay of treatment is a gluten-free diet (GFD).
- Conditions
- Celiac Disease in Children, Gluten Enteropathy, Diet; Deficiency, Adherence, Treatment
- Trial name
- NCT06038344
- Testing
- Gluten-free food guide teaching
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Celiac Disease in Children
Intestinal Fatty Acid-binding Protein (I-FABP) Levels in Pediatric Celiac Patients
A prospective, longitudinal study meant to compare blood levels of I-FABP in pediatric celiac patients during diagnosis to levels under gluten free diet, it's correlation with traditional serology testing and questionnaire…
- Trial name
- NCT03244254
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Schneider Children's Medical Center, Israel
Short Bowel Syndrome
Safety and Immunogenicity of Rotavirus Vaccine (RotaTeq(R)) in Infants With Short Bowel Syndrome
Rotavirus infection is a common pediatric illness and is the leading cause of severe acute gastroenteritis (vomiting and diarrhea) in infants and young children.
- Trial name
- NCT00767364
- Testing
- Oral, live, pentavalent rotavirus vaccine; RotaTeq(R)
- Where
- 3 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Michigan
Type 1 Diabetes, Celiac Disease
Accessing Care, Clinical Trials and Screening for Underserved Children and Adults With Type 1 Diabetes (ACCESS-T1D)
The purpose of this study is to identify people with T1D or celiac disease (CD) early in the course of their disease and to improve the methods of screening for these diseases.
- Trial name
- ACCESS-T1D (NCT06908057)
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Celiac Disease
Can a Very High Result From a Screening Test for Celiac Disease be Used to Diagnose Celiac Disease?
This study is to see if a high response to the TTG screening test for celiac disease is as accurate as the current method of diagnosing celiac disease which entails a general anesthetic and upper endoscopy to obtain biopsies of…
- Trial name
- NCT00175760
- Testing
- Diagnosis of Celiac Disease
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia