Clinical trials: Mandible Small
Class II Malocclusion
The Use of an Esthetic Twin Block for Patients With Mandibular Retrusion
This experimental study will evaluate the effect of an esthetic Twin-block appliance on the correction of class II malocclusion compared with the traditional Twin-block appliance.
- Trial name
- NCT05418413
- Testing
- CTB, ETB
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Growth Modification
Three-Dimensional Assessment of Dentoskeletal Changes Associated With a Modified Twin Block Appliance
The aim of the current study is to evaluate the skeletal, dental, soft tissue, TMJ, and upper airway size changes associated with a new design of twin block compared to the conventional twin block appliance.
- Trial name
- NCT06589206
- Testing
- modified design of twin block
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Malocclusion
Laser in Orthodontic Leveling and Alignment
to evaluate the outcome of LLLT regarding leveling and alignment of the mandibular anterior segment.
- Trial name
- NCT04376164
- Testing
- low level laser therapy
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Tharwat osman Mohi Eldeen Elshehawy
Malocclusion, Angle Class II
Effects of Modified Fixed Twin Block Versus Removable Twin Block on Skeletal Class 2 Growing Patients With Mandibular Deficiency
Effects of modified fixed twin block versus removable twin block on skeletal class 2 growing patients with mandibular deficiency: A Randomized Clinical Trial
- Conditions
- Malocclusion, Angle Class II, Mandible Small
- Trial name
- NCT05993156
- Testing
- modified Fixed twinblock, removable twin block
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Micrognathia of Lower Jaw, Retrognathism
Comparison Between Internal and External Distractors in Osteogenesis
Distraction osteogenesis is a powerful technique for creating new bone during significant lengthening of the mandible without the need for bone grafting and associated donor site morbidity.
- Conditions
- Micrognathia of Lower Jaw, Retrognathism, Facial Asymmetry
- Trial name
- NCT03540329
- Testing
- Internal Osteogenesis distractor, External Osteogenesis distractor
- Volunteers
- 30 people
- Sponsor
- Assiut University
Benign Thoroid Disease Requiring Total Thyroidectomy
Clinical Trial on Harmonic Focus Shears Versus Ligasure Small Jaw and Clamp-and-tie Technique for Total Thyroidectomy
The Harmonic Focus and Ligasure small-Jaw are the last device designed for thyroid surgery. The aim is to assess: 1. decrease of operative time (minutes); 2. decrease of post-operative blood loss (milliliters); 3.
- Trial name
- NCT01649154
- Testing
- Total Thyroidectomy with cut and tie technique vs Total Thyroidectomy with Ligasure Small-JAW vs Total Thyroidectomy with Harmonic Focus
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Ospedale Regina Apostolorum
Skeletal Malocclusion
Cephalometric Evaluation of a Clear Mandibular Advancement Appliance Based on the Twin-block Design
This study evaluates the cephalometric effects of a clear mandibular advancement appliance for the treatment of skeletal class II growing patients suffering from mandibular deficiency.
- Trial name
- NCT03824574
- Testing
- Clear Mandibular Advancement Appliance
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Schizophrenia, Micrognathia
The Relevance Between the microRNA-30e in Plasma and the Prognosis of Schizophrenia Patients
This study investigates the relationship of circulating microRNA-30e and schizophrenia, and shows the relevance of the aberrant microRNA-30e expression in plasma with the variation disease status.
- Trial name
- NCT03007303
- Testing
- Atypical Antipsychotic, atypical antipsychotic combined with MECT
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dalian Seventh People's Hospital
Skeletal Class II Malocclusion, Mandibular Retrognathia
Fixed Versus Conventional Twin Block Appliances for Skeletal Class II Malocclusion
This study compares two types of dental appliances a fixed Twin Block appliance and a conventional (removable) Twin Block appliance used to treat a bite problem called skeletal Class II malocclusion in growing children and…
- Trial name
- NCT07687927
- Testing
- Conventional Twin Block Appliance
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion, Angle Class II
Effect of Skeletally Anchored Herbst Appliance in Treatment of Skeletal Class 2 Due to Mandibular Retrusion
Ten adolescent female patients with Class 2 mandibular deficiency with a mean age of 16.5 ±1.71 years treated with type IV Herbst appliance.
- Trial name
- NCT04388046
- Testing
- Herbst fixed functional appliance
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Khaled ELHabbak
Skeletal Class 2
Evaluation of the Effects of Flat and Modified Inclined Fixed Anterior Bite Planes on Mandibular Position in Growing Females With Skeletal Class 2 Malocclusion Due to Mandibular Deficiency and Deep Bite
This study will be conducted to see if unlocking mandible from deep bite in growing females by flat fixed anterior bite plane will change mandibular position in skeletal mandibular deficiency and if there is a difference in the…
- Trial name
- NCT03308175
- Testing
- flat fixed anterior bite plane, modified inclined fixed anterior bite plane
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Class II Malocclusion, Mandibular Deficiency
Dentoskeletal Effects of 3D-Printed Fixed Twin Block Versus MARA Appliances in Management of Skeletal Class II
Objective: to evaluate the dentoskeletal effects of CAD/CAM 3D-Printed fixed twin block versus MARA appliances in the management of skeletal class II due to Mandibular Deficiency in Preadolescence Class II malocclusion is…
- Trial name
- NCT07340242
- Testing
- MARA appliance, fixed twin block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Mandibular Retrognathism, Mandibular Hypoplasia
Twin Block Appliance in Incremental Versus Maximum Bite Advancement in Skeletal Class II
The aim of this study is to compare to different protocols to treat Class II malocclusion in growing subjects using the twin block appliance
- Trial name
- NCT04562545
- Testing
- Modified Twin Block, Twin Block Appliance set to maximum bite
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Surgical Complication, Paresthesia
Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation
The aim of this prospective study is to analyze the postoperative paresthesias experienced in patients who undergo bilateral sagittal split osteotomies (BSSO) using an ultrasonic saw, versus a reciprocating saw.
- Conditions
- Surgical Complication, Paresthesia, Fracture, Nerve Injury
- Trial name
- NCT05205616
- Testing
- Sonopet ultrasonic saw, Reciprocating saw
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Mandibular Hypoplasia
Comparing Stability and Cost-Effectiveness of 3 Bicortical Screws Vs Adjustable Plate and 2 Bicortical Screws in Fixation of BSSRO
In this current study a comparison between 3 positional screws versus the adjustable plating system in conjunction with 2 positional screws. The patients will be selected to have retrognathic mandible requiring advancement.
- Trial name
- NCT02950727
- Testing
- 3 bicortical screws, adjustable plate and 2 bicortical screws
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Joseph Van Sickels
Mandibular Hypoplasia, Relapse
Evaluation of Early Relapse After Mandibular Lengthening Surgery
The goal of this study is to evaluate whether the use of a bone graft substitute at the osteotomy site will result in better stability and diminish early relapse after mandibular lengthening surgery.
- Trial name
- NCT03710512
- Testing
- Bilateral sagittal split osteotomy
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitair Ziekenhuis Brussel
Apnea, Airway Obstruction, Nasal
Upper Airway's Pressure Drop Analyses After Mandibular Advancement and Maxillary Expansion
Breathing is a crucial function for everyone. Breathing impairment in children could lead to behavioral and cognitive problems at least.
- Conditions
- Apnea, Airway Obstruction, Nasal, Mandible Small, Maxillary Hypoplasia
- Trial name
- NCT04190953
- Testing
- Twin block then Hyrax, Hyrax then Twin block
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Craniofacial Abnormalities, Mandibular Hypoplasia
Dexmedetomidine Versus Sevoflurane in Children With Anticipated Difficult Intubation
difficult problem in the paediatric age group because of their small mouth opening and un-cooperativeness.Currently used methods of sedation for fibreoptic intubation such as benzodiazepines, propofol or opioids may cause…
- Trial name
- NCT04426552
- Testing
- dexmedetomidine, sevoflurane
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Sleep Apnea Syndromes in Children, Functional Orthodontic Treatment
Evaluation of Functional Orthodontic Treatment on Sleep Quality
Functional appliances are used in the treatment of Class II anomalies caused by mandibular rethrognathia. Herbst which is a fixed and rigid functional appliance and TWB which is removable appliance can be successful in the…
- Conditions
- Sleep Apnea Syndromes in Children, Functional Orthodontic Treatment, Mandibular Retrognathia, Upper Airway
- Trial name
- NCT06660771
- Testing
- Functional orthodontic treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Gökçenur Gökçe Kara
Cleft Palate, Cleft Lip
Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring
Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population.
- Conditions
- Cleft Palate, Cleft Lip, Laryngospasm, Bronchospasm
- Trial name
- NCT07651904
- Testing
- Standard General Anesthesia per Institutional Protocol
- Volunteers
- 150 people
- Sponsor
- Marmara University Pendik Training and Research Hospital