Clinical trials: Mandibular Retrognathia
Cleft Lip and Palate, Maxillary Hypoplasia
Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better?
Cleft lip and palate patients normally present with a sunken face due to collapse in the middle part of the face and inability of the upper and lower teeth to meet during chewing.
- Trial name
- NCT00930124
- Testing
- Orthognathic surgery, Distraction osteogenesis
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Class III Malocclusion, Maxillary Deficiency
Evaluation of Pain and Functional Impairments When Treating Class III Malocclusion Using Two Treatment Procedures
A clinical examination of each recalled candidate patient will be carried out at Adib Al Lahham Centre at the Ministry of Health Damascus to ensure that he/she meets the inclusion criteria.
- Trial name
- NCT06877780
- Testing
- RMR with SME, BAIMT with RME
- Where
- Syria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Damascus University
Class II Malocclusion
The Use of an Esthetic Twin Block for Patients With Mandibular Retrusion
This experimental study will evaluate the effect of an esthetic Twin-block appliance on the correction of class II malocclusion compared with the traditional Twin-block appliance.
- Trial name
- NCT05418413
- Testing
- CTB, ETB
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Growth Modification
Three-Dimensional Assessment of Dentoskeletal Changes Associated With a Modified Twin Block Appliance
The aim of the current study is to evaluate the skeletal, dental, soft tissue, TMJ, and upper airway size changes associated with a new design of twin block compared to the conventional twin block appliance.
- Trial name
- NCT06589206
- Testing
- modified design of twin block
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Class II Malocclusion, Mandibular Retrognathism
Comparison Of The Effects Of Clear Aligners And Twinblock Appliances In Functional Treatment Of Class II Malocclusion
This prospective clinical study aimed to compare the skeletal and dentofacial effects of Twin Block (TWB) and clear aligners with mandibular advancement, and to evaluate mandibular trabecular bone changes through fractal analysis…
- Trial name
- NCT07454694
- Testing
- Invisalign Clear Aligners, Twinblock Functional Appliance
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Bezmialem Vakif University
Dental Malocclusion, Maxillary Deficiency
Effect on Periodontal Phenotype of Flapless Piezoincission During Orthodontic Treatment
Research Question While the reduction in treatment times and the patient satisfaction after periodontally accelerated osteogenic orthodontics (PAOO) are well sustained in the scientific literature, there is still controversy…
- Trial name
- Piezo_Ortho (NCT06315348)
- Testing
- flapless alveolar decortication with augmentation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Maxillary Deficiency, Cleft Lip and Palate
Evaluation of Maxillary Expansion Using Clear Aligners' Therapy in Patients With Cleft Lip and Palate at the Mixed Dentition Stage
The goal of this clinical trial is to learn if the aligners can expand upper dental arch in patients with cleft lip and palate at age of 6-8 years old to correct their collapsid archs.
- Trial name
- Pilot (NCT06994754)
- Testing
- clear aligners
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Maxillar Hypoplasia
Evaluation of Masticatory Muscle Activity in Pediatric Patients Undergoing Rapid Maxillary Expansion
Transverse maxillary constriction is a malocclusion that subsists when the distance between the upper first molars palatal cuspids is lower than the distance between the lower first molars vestibular center fossae.
- Trial name
- NCT05820438
- Testing
- Electromyography
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- University of Pavia
Malocclusion, Angle Class II
Effects of Modified Fixed Twin Block Versus Removable Twin Block on Skeletal Class 2 Growing Patients With Mandibular Deficiency
Effects of modified fixed twin block versus removable twin block on skeletal class 2 growing patients with mandibular deficiency: A Randomized Clinical Trial
- Conditions
- Malocclusion, Angle Class II, Mandible Small
- Trial name
- NCT05993156
- Testing
- modified Fixed twinblock, removable twin block
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Micrognathia of Lower Jaw, Retrognathism
Comparison Between Internal and External Distractors in Osteogenesis
Distraction osteogenesis is a powerful technique for creating new bone during significant lengthening of the mandible without the need for bone grafting and associated donor site morbidity.
- Conditions
- Micrognathia of Lower Jaw, Retrognathism, Facial Asymmetry
- Trial name
- NCT03540329
- Testing
- Internal Osteogenesis distractor, External Osteogenesis distractor
- Volunteers
- 30 people
- Sponsor
- Assiut University
Benign Thoroid Disease Requiring Total Thyroidectomy
Clinical Trial on Harmonic Focus Shears Versus Ligasure Small Jaw and Clamp-and-tie Technique for Total Thyroidectomy
The Harmonic Focus and Ligasure small-Jaw are the last device designed for thyroid surgery. The aim is to assess: 1. decrease of operative time (minutes); 2. decrease of post-operative blood loss (milliliters); 3.
- Trial name
- NCT01649154
- Testing
- Total Thyroidectomy with cut and tie technique vs Total Thyroidectomy with Ligasure Small-JAW vs Total Thyroidectomy with Harmonic Focus
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Ospedale Regina Apostolorum
Maxillary Deficiency
Associations Between Radiographic Inclination of Premolars and Maxillary Expansion
Recruitment of patients treated using rapid maxillary expanders with dental anchorage, with pre-treatment panoramic X-rays and post-treatment models.
- Trial name
- NCT07095374
- Testing
- Rapid palatal expansion
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Pavia
Mandibular Retrognathism
Comparison of Distalization and Functional Appliance Therapy
The correction of Class II malocclusion is one of the most common problems facing the orthodontist, with an estimated one-third of all orthodontic patients treated for this condition.
- Trial name
- NCT03252782
- Testing
- Herbst Appliance, Distal Jet Appliance
- Volunteers
- 30 people
- Sponsor
- Izmir Katip Celebi University
Skeletal Malocclusion
Cephalometric Evaluation of a Clear Mandibular Advancement Appliance Based on the Twin-block Design
This study evaluates the cephalometric effects of a clear mandibular advancement appliance for the treatment of skeletal class II growing patients suffering from mandibular deficiency.
- Trial name
- NCT03824574
- Testing
- Clear Mandibular Advancement Appliance
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Maxillary Hypoplasia
Effectiveness of SARPE With 3 and 2-Segment Technique: A Randomized Clinical Trial
A few studies state that 3-segment SARPE has the following advantages: a) higher level of expansion symmetry; b) higher level of stability of the expansion achieved; and c) faster bone healing.
- Trial name
- 3S/2S_SARPE (NCT02179593)
- Testing
- 2-Segment SARPE, 3-Segment SARPE
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Federal University of São Paulo
Maxillary Retrognathism, Children
Treatment of Mandibular Overjet in Children With Maxillary Retrognathism
The project involves a 10-year prospective longitudinal cohort multicentre study where orthodontic treatment and treatment effect is followed in children with Cl III due to maxillary retrognathia who undergo standardized…
- Conditions
- Maxillary Retrognathism, Children, Treatment, Class III Malocclusion
- Trial name
- NCT07706400
- Testing
- Interceptive treatment
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Malmö University
Prognathism, Retrognathia
Transoral Versus Transbuccal Placement of Bicortical Screws During Orthognathic Surgery
Bicortical screws have been widely used for mandibular osteosynthesis during orthognathic surgery.Transoral placement of bicortical screws is a rigid fixation method in orthognathic surgery, which is less often used.
- Conditions
- Prognathism, Retrognathia, Jaw Abnormalities
- Trial name
- NCT02658305
- Where
- Belgium
- Volunteers
- 509 people
- Sponsor
- AZ Sint-Jan AV
Peri-operative Hemorrhage or Hematoma, Surgery
Preventive EXACYL® on Perioperative Bleeding During Orthognathism of Maxillary Surgery
Prospective, randomized, double-blind, placebo-controlled, mono center, Phase III trial to compare EXACYL in preventive with placebo on perioperatory bleeding in orthognathism surgery.
- Conditions
- Peri-operative Hemorrhage or Hematoma, Surgery, Retrognathism
- Trial name
- LEFORTEXACYL (NCT02702128)
- Testing
- Tranexamic Acid, saline solution
- Where
- France
- Volunteers
- 157 people
- Sponsor
- University Hospital, Lille
Schizophrenia, Micrognathia
The Relevance Between the microRNA-30e in Plasma and the Prognosis of Schizophrenia Patients
This study investigates the relationship of circulating microRNA-30e and schizophrenia, and shows the relevance of the aberrant microRNA-30e expression in plasma with the variation disease status.
- Trial name
- NCT03007303
- Testing
- Atypical Antipsychotic, atypical antipsychotic combined with MECT
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dalian Seventh People's Hospital
Skeletal Class II Malocclusion, Mandibular Retrognathia
Fixed Versus Conventional Twin Block Appliances for Skeletal Class II Malocclusion
This study compares two types of dental appliances a fixed Twin Block appliance and a conventional (removable) Twin Block appliance used to treat a bite problem called skeletal Class II malocclusion in growing children and…
- Trial name
- NCT07687927
- Testing
- Conventional Twin Block Appliance
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University