Clinical trials: Maternal Substance Use
Tobacco Smoking in Mother Complicating Pregnancy, Tobacco Use Disorder
Smoking Reduction In Gravid Substance Use Disorders
The aim of this study is to encourage smoking cessation in women with substance use disorders by providing knowledge of expired carbon monoxide.
- Conditions
- Tobacco Smoking in Mother Complicating Pregnancy, Tobacco Use Disorder, Tobacco Smoking
- Trial name
- SIGS (NCT04132232)
- Testing
- knowledge of expired maternal carbon monoxide and fetal carboxyhemoglobin levels
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Substance Use Disorders, Children of Mothers With Substance Use Disorders
Parenting Intervention for Mothers With Substance Use Disorder
Children of mothers with substance use disorder (SUD) constitute a growing and highly vulnerable population. Evidence-based parenting interventions have the potential to both support parents' recovery and mental health by helping…
- Trial name
- NCT06489522
- Testing
- THRIVE
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Boston Medical Center
Substance Use Disorders
Interventions for HIV+ Mothers With Problem Drinking
The purpose of this study is to evaluate the efficacy of a 14-session behavioral intervention for HIV-infected and uninfected mothers with problem drinking.
- Trial name
- NCT00183209
- Testing
- Family First
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- New York University
Substance Use
Drug Abuse Prevention Among Girls Through a Mother-Daughter Intervention
The purpose of this study is to determine a computer- and family-based drug abuse prevention program is able to reduce drug use among early adolescent girls.
- Trial name
- NCT01236248
- Testing
- Prevention
- Where
- United States
- Volunteers
- 916 people, healthy volunteers welcome
- Sponsor
- Columbia University
Substance Addiction
Maternal Acupuncture for Substance Abuse
To determine the efficacy of daily maternal acupuncture treatments in reducing the frequency and severity of neonatal abstinence syndrome among infants born to substance-using women..
- Trial name
- NCT00225316
- Testing
- Acupuncture
- Where
- Canada
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Behavioral Health
Improving Future Thinking Among Mothers to Reduce Harsh Parenting and Improve Child Outcomes
Parents of children from impoverished communities are disproportionately more likely to engage in harsh physical discipline, which can lead to serious clinical outcomes, including suicidal ideation and attempts.
- Trial name
- NCT05229146
- Testing
- Episodic Future Thinking
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Mother-Child Relations, Substance Use
Optimizing Mental Health for Infants Exposed to Early Adversity: A Comparison of Breaking the Cycle and Maxxine Wright
The goal of this clinical trial is to compare the effectiveness of the Breaking the Cycle (BTC) and Maxxine Wright (MW) programs in substance-involved mothers and their children.
- Trial name
- NCT05768815
- Testing
- Breaking the Cycle Program, Maxxine Wright Program
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of Ottawa
Child Behavior, Parent-Child Relations
A Scaleable Video Coaching Intervention for Opioid-using Mothers
This study will adapt and evaluate a novel, innovative, and highly scalable parenting intervention that employs video coaching to target responsive parenting, Filming Interactions to Nurture Development (FIND), among women who…
- Conditions
- Child Behavior, Parent-Child Relations, Substance Use, Substance Abuse
- Trial name
- NCT04749771
- Testing
- Filming Interactions to Nurture Development, The Healthy Toddler Program
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Oregon
Substance Use Disorders, Parent-Child Relations
MIO-CPP to Improve the Well-being, Permanency, and Safety Outcomes for Young Children at Risk of or in Out-of-home Placement in Philadelphia and Bucks Counties, and Affected by Maternal Substance Use
The goal of the project is to improve child well-being, permanency, and safety, and reduce the risk for involvement in the child welfare system for families with children pre-birth to five years who are affected by parental…
- Conditions
- Substance Use Disorders, Parent-Child Relations, Parent Child Abuse
- Trial name
- NCT04294134
- Testing
- MIO-CPP
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- Children's Hospital of Philadelphia
Opioid-Related Disorders, Drug Addiction
Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study
This is a sub-study of NIDA CTN Protocol 0080: Medication Treatment for Opioid Use Disorder in Expectant Mothers (MOMs; Unique protocol ID: 2019-0429-1).
- Conditions
- Opioid-Related Disorders, Drug Addiction, Pregnancy Related, Substance Abuse
- Trial name
- MOMs-INO (NCT03911739)
- Testing
- Buprenorphine Injection, Buprenorphine Sublingual Product
- Where
- 10 sites in United States
- Volunteers
- 71 people
- Sponsor
- T. John Winhusen, PhD
Opioid Use Disorder, Neonatal Abstinence Syndrome
RESPECT-PLUS: Services for Infants With Prenatal Opiate Exposure
The impact of parental opioid use disorder and other substance use exposure on child welfare and the healthcare system is undeniable.
- Conditions
- Opioid Use Disorder, Neonatal Abstinence Syndrome, Child Development, Child Abuse
- Trial name
- RESPECT-Plus (NCT02334111)
- Testing
- RESPECT-Plus
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Medical Center
Cannabis Use, Marijuana Use
Cannabis Use in Pregnancy and Downstream Effects on Maternal and Infant Health
With perinatal cannabis use rising in Canada, robust data on short-term and long-term effects on newborns are urgently needed. However, past barriers to obtain robust data included limited sample sizes, low self-reporting and no…
- Trial name
- CUPiD (NCT05309226)
- Testing
- Cannabis use in pregnancy or cannabis exposure in utero
- Where
- 4 sites in Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Substance-Related Disorders, Alcohol-Related Disorders
Conflict Between Maternal Autonomy and Child Health in Substance-use
Qualitative project, comprising open-ended semi-structured interviews with healthcare workers, who provide antenatal care to substance-using women.
- Conditions
- Substance-Related Disorders, Alcohol-Related Disorders, Amphetamine-Related Disorders, Inhalant Abuse
- Trial name
- NCT02797990
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Perinatal Opioid Use Disorder, Opioid Use Disorder
Adapting the Penny Chatbot for Perinatal OUD Patients: COPILOT
To address both loneliness and engagement in perinatal and OUD care among perinatal women, the investigators plan to adapt an existing texting support chatbot, Penny, to make it appropriate for use by women who are pregnant and…
- Trial name
- PENNY-COPILOT (NCT06969261)
- Testing
- Penny COPILOT
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania