Clinical trials: Medication Interaction
Acquired Immunodeficiency Syndrome, HIV Infections
Once-Daily Drug Regimen for HIV-Infected Patients
This study will examine the safety of giving antiviral therapy for HIV infection in a once-daily dosing schedule, and assess how well patients tolerate this regimen.
- Trial name
- NCT00001968
- Testing
- Amprenavir, Ritonavir, Abacavir
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Fetal Growth, Obstetric Ultrasonography
Clinicians' Trust in AI-Based Fetal Growth Estimates
This study examines how clinicians trust and use artificial intelligence (AI) when estimating fetal weight during pregnancy. Accurate assessment of fetal growth is important for identifying growth problems that may affect…
- Conditions
- Fetal Growth, Obstetric Ultrasonography, Pregnancy, Clinical Decision-making
- Trial name
- NCT07401368
- Testing
- Intervention - AI Performance Information
- Where
- Denmark
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pain (Visceral, Somatic, or Neuropathic), Women of Reproductive Age
Virtual Menstrual Pain Approaches in Females
This research study is testing two self-care approaches that may help prevent or reduce period pain in young females with recurrent painful menstrual cramps.
- Conditions
- Pain (Visceral, Somatic, or Neuropathic), Women of Reproductive Age, Mental Disorder, Digital Health
- Trial name
- AABQ (NCT07497711)
- Testing
- Virtual Auricular Acupressure, Virtual Baduanjin Qigong Exercise, Self Education
- Where
- Singapore
- Volunteers
- 145 people
- Sponsor
- Nanyang Technological University
Community Pneumonia
The Association Mechanism Between the Microbiome and the Development of Community Pneumonia Was Studied Based on the Analysis of Pulmonary Microbiota - Host Interaction Network
1. The difference of lung flora between the healthy group and the CAP group was compared, and the core flora involved in the development of CAP was identified. 2. To predict the metabolites associated with CAP. 3.
- Trial name
- NCT06896019
- Testing
- Community Pneumonia
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Healthy
Cranberry Flavan-3-ols Consumption and Gut Microbiota in Healthy Adults
Consumption of (poly)phenols is recognized to have beneficial effects on health. However, heterogeneous results are obtained in clinical trials due to high inter-individual variability.
- Trial name
- NCT05931237
- Testing
- Cranberry extract capsules
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Laval University
Stress Disorders, Post-Traumatic, Helping Behavior
Clinical Trial of a Supporter-Targeted Intervention to Improve Outcomes in Recent Sexual Assault Survivors
Communication and Recovery Enhancement (CARE) is a 2-session early intervention for survivors of recent sexual assault and their supporters that aims to improve supporters' ability to respond effectively.
- Conditions
- Stress Disorders, Post-Traumatic, Helping Behavior, Help-Seeking Behavior, Stress
- Trial name
- CARE (NCT05345405)
- Testing
- Dyadic CARE, Supporter-Only CARE
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Washington
Pediatric Disorder, Genetic Predisposition
Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy
This study looks at how a medicine called trihexyphenidyl works in children with dystonic cerebral palsy. The study aims to understand how trihexyphenidyl is broken down and used in the body of pediatric patients and whether this…
- Conditions
- Pediatric Disorder, Genetic Predisposition, Dystonia, Secondary, Dystonia
- Trial name
- TRIKE2 (NCT06554288)
- Testing
- Trihexyphenidyl
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Mercy Hospital Kansas City
Obsessive-Compulsive Disorder
Family Focused Treatment of Pediatric Obsessive Compulsive Disorder
Pediatric obsessive compulsive disorder (OCD) is a chronic, impairing condition that accrues significant concurrent and long-term risk to affected youth (Piacentini et al. 2003; Pine et al. 1998).
- Trial name
- PFIT (NCT01409642)
- Testing
- Individual Child CBT, Positive Family Interaction Therapy
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of California, Los Angeles
Mental Health, Physical Fitness
Mixed PE Program Using Sports Games and Ball Sports in Left-Behind Children
This randomized controlled trial evaluates whether a 12-week school-based physical education program that combines cooperative sports games and ball sports can improve mental health and physical fitness in rural left-behind…
- Conditions
- Mental Health, Physical Fitness, Left-Behind Children
- Trial name
- MIXPE-LBC (NCT07452302)
- Testing
- Mixed Physical Education Program, Usual Physical Education
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Anhui Normal University
Autoimmune Hepatitis
Host-Diet-Gut Interaction Post Vegan Diet in Pediatric Autoimmune Hepatitis.
Pediatric autoimmune liver diseases (AILDs), including autoimmune hepatitis (AIH) and overlap syndromes like sclerosing cholangitis, are among the most common chronic liver conditions in the pediatric population.
- Trial name
- NCT07118657
- Testing
- Vegan Diet, Standard Diet
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Stuttering, Down Syndrome
How Stuttering and Gestures Influence the Intelligibility of Individuals With Down Syndrome
This study wants to determine the relationship between spontaneous hand gestures, stuttering and intelligibility in individuals with Down syndrome. One third of these individuals has fluency problems, such as stuttering.
- Conditions
- Stuttering, Down Syndrome, Intelligibility, Speech, Gestures
- Trial name
- NCT03698539
- Testing
- hand gestures
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Language Development, Language Delay
A Language Intervention Study of Preterm Infants
This is a randomized controlled trial to study a reading intervention in the NICU among preterm infants using LENA (Language Environment Analysis) recordings, linguistic feedback, and a language curriculum to improve the neonatal…
- Conditions
- Language Development, Language Delay, Mother-Infant Interaction, Maternal Behavior
- Trial name
- NCT03688386
- Testing
- Reading intervention, Infant bonding, LENA recording
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Autism Spectrum Disorder, Visual Rehabilitation
Visual Rehabilitation in Children With Autism Spectrum Disorder and Visual Disorders
Children with autism spectrum disorder (ASD) often have visual problems that add difficulty to social interaction and communication.
- Conditions
- Autism Spectrum Disorder, Visual Rehabilitation, Vision, Social Communication
- Trial name
- NCT07644468
- Testing
- Visual Rehabilitation
- Where
- Taiwan
- Volunteers
- 9 people
- Sponsor
- National Taiwan University Hospital
Disruptive Behavior
A Study of Internet Delivered Parent Child Interaction Therapy
The purpose of this study is to learn more about how feasible remote parent child interaction therapy (PCIT) is for children with disruptive behaviors and how to augment treatment with wearable devices.
- Trial name
- AI I-PCIT (NCT05725525)
- Testing
- Remote PCIT augmented with wearable devices
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Behavior Problems in Children, Parent-Child Relations
Dino Study: Daily Intervention-based Research on Nurturing Opportunities in Young Children
The goal of this clinical trial is to evaluate the effectiveness of the Incredible Years Dinosaur Program in children aged 4 to 8 years with conduct problems.
- Conditions
- Behavior Problems in Children, Parent-Child Relations, Oppositional Behavior, Social Skills
- Trial name
- Dino (NCT07051642)
- Testing
- Incredible Years Dinosaur Child Program
- Where
- Netherlands
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tilburg University
Breast Cancer, Cancer
Vinorelbine and XR9576 to Treat Cancer
Tumor resistance to anti-cancer drugs is a major problem in cancer treatment. Studies have found that a protein (P-glycoprotein) on some cancer cells pumps chemotherapy drugs out of the cells, reducing treatment effectiveness.
- Conditions
- Breast Cancer, Cancer, Lung Cancer, Ovarian Cancer
- Trial name
- NCT00001944
- Testing
- Vinorelbine, XR9576
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
Acute Respiratory Failure With Hypoxia
NAVA Helmet in Pediatric Respiratory Failure
Neurally Adjusted Ventilatory Assist (NAVA) is a new form of partial support wherein the machine applies positive pressure throughout inspiration in proportion to the electrical activity of the diaphragm (EAdi), Because…
- Trial name
- NCT02050217
- Testing
- Neurally Adjusted Ventilatory Assist
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Premature Births
Long-term Effect of The Mother Infant Transaction Program (MITP)
The purpose of this study is to investigate if a cost and time effective intervention in a previous RCT for preterm infants and their parents can reduce the parents experience of concern and stress, and improve the childrens…
- Trial name
- 2007/2/0150 (NCT00903149)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Child Behavior, Parenting
Natural Helpers and PCIT
The purpose of the study is to evaluate the effect of a time-limited (i.e., 18 weeks) community health worker (CHW) intervention, referred to as the Parent Child Interaction Therapy (PCIT) plus natural helper (NH) model, on…
- Trial name
- NCT05400434
- Testing
- Standard Parent-Child Interaction Therapy (PCIT), Natural Helpers (NH)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Miami
Development Delay
Parent-Child Interaction in Garding Activities for Early Intervention Preschool Children
Post-COVID-19, children's reduced interaction with nature has hindered their sensory development, particularly affecting those with developmental delays.
- Trial name
- NCT06507358
- Testing
- Parent-Child Interaction group
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital