Clinical trials: Medication Interaction
Autism Spectrum Disorder
SPARK Exercise Program and Game-based Training in Children With Autism Spectrum Disorder
This randomized controlled trial (RCT) will compare the effects of the SPARK program versus game-based circuit training on motor skills and social interaction in 22 children with Autism Spectrum Disorder (ASD) aged 5-12 years.
- Trial name
- NCT07579000
- Testing
- Structured Sports, Play, and Active Recreation for Kids Exercise program (SPARK), Game-based Training
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
HIV, Tuberculosis
Rifampin and Efavirenz Interactions in Older Children
Efavirenz is an essential component of HIV treatment in children aged 3 years or older on anti-tuberculosis (anti-TB) treatment. However, the appropriate efavirenz dose during anti-TB treatment remains unclear.
- Trial name
- NCT01704144
- Where
- Ghana
- Volunteers
- 160 people
- Sponsor
- The Miriam Hospital
Infant Development
Interactions Between Environmental Exposures and Gut Microbiota in Early Life
Recruit the mothers and their infants who bron in Peking University People's Hospital from 2023 to 2026, to evaluate the interaction between environmental exposure and gut microbiota.
- Trial name
- NCT06479928
- Testing
- delivery mode
- Where
- China
- Volunteers
- 756 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Healthy
Effect of Ginkgo Biloba on Phenytoin Elimination
This study will examine how the herbal remedy ginkgo biloba may affect the body's elimination of other medicines. Many people take ginkgo biloba to improve memory, mental alertness and overall feeling of well being.
- Trial name
- NCT00011063
- Testing
- Ginkgo Biloba
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Violence by Teachers
Preventing Violence by Teachers in Primary Schools in Haiti
Violence has severe and long-lasting negative consequences for children's and adolescents' well-being and academic functioning, which can hinder communities' and societies' economic growth.
- Trial name
- ICC-T_HAITI (NCT05081622)
- Testing
- Interaction Competencies with Children - for Teachers (ICC-T)
- Where
- Haiti
- Volunteers
- 1,064 people, healthy volunteers welcome
- Sponsor
- Bielefeld University
Violence by Teachers
Preventing Violence by Teachers
Brief Summary: Violence against children is regarded as a key contributor to poverty and damages lifetime prospects for children in disadvantaged communities.
- Trial name
- ICC-T_Tz (NCT03893851)
- Testing
- Interactions Competencies with Children - for Teachers (ICC-T)
- Where
- Tanzania
- Volunteers
- 914 people, healthy volunteers welcome
- Sponsor
- Bielefeld University
Cystic Fibrosis
Cystic Fibrosis Microbiome-determined Antibiotic Therapy Trial in Exacerbations: Results Stratified
Antimicrobial resistance is a significant challenge facing global healthcare. The unnecessary use of antibiotics is a key driver in the development of antibiotic resistance.
- Trial name
- CFMATTERS (NCT02526004)
- Testing
- Ceftazidime, Tobramycin
- Where
- Ireland
- Volunteers
- 223 people
- Sponsor
- University College Cork
Premature Birth
Effects of Early Intervention for Preterm Children at School Age
Despite the remarkable achievements in neonatal survival of preterm infants with very low birth weight (VLBW, birth weight < 1,500 g) over the past three decades, improvements have produced little change in their prevalence of…
- Trial name
- NCT01952093
- Testing
- Home-based intervention program, Clinic-based intervention program
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
HIV Prevention
Digital Limited Interaction Efficacy Trial of LifeSkills Mobile to Reduce HIV Incidence in YTW
The LifeSkills Mobile app will be evaluated in a randomized controlled trial (RCT) among 5,000 young transgender women (YTW), ages 16-29 in the United States (U.S.).
- Trial name
- LifeSkills (NCT05018611)
- Testing
- LifeSkills Mobile
- Where
- United States
- Volunteers
- 5,100 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Anxiety
School-Based Treatment for Early Childhood Anxiety
This pilot will be used for academic research, in hopes of developing effective treatments for early childhood anxiety. The intervention is an adaptation of Parent-Child Interaction Therapy (PCIT).
- Trial name
- NCT04811482
- Testing
- TCIT-CALM (Teacher-Child Interaction Training-CALM)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
HIV Infections
A Phase I Trial to Evaluate the Safety and Pharmacokinetics of 1592U89
To assess the safety of single oral doses of 1592U89 (abacavir succinate, ABC) administered to HIV-positive individuals. To determine the pharmacokinetics of 1592U89 after single oral doses.
- Trial name
- NCT00002141
- Testing
- Abacavir sulfate
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Burroughs Wellcome
Anxiety, Pain
Effect of Augmented Reality on Dental Anxiety and Pain Perception in Children
The aim of this study is to reduce dental anxiety in children by using augmented reality (AG) with a special content and innovative interactive methods, to determine the level of stress experienced by patients during dental…
- Trial name
- NCT06530654
- Testing
- Distraction by dentist, Distraction by cartoon movie, AG-active distraction group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Istanbul University
COVID, Drug Effect
Assessment of Mortality Rates in COVID-19 Infected Populations Treated With Repurposed Medications
This retrospective cohort study will include eligible patients that received a positive COVID-19 test and filled a new prescription for one of the repurposed medications (including hydroxychloroquine, chloroquine, with or without…
- Conditions
- COVID, Drug Effect, Drug Interaction, Risk Reduction
- Trial name
- NCT04432350
- Where
- United States
- Sponsor
- Tabula Rasa HealthCare
Sport Injury, Hamstring Injury
System Dynamics Model for Acute Non-contact Lower Extremity Injuries Prediction
Despite the extensive research on prevention and prediction strategies, hamstrings strains injury (HSI) persists at a high rate in team sports and specifically in football.
- Conditions
- Sport Injury, Hamstring Injury, Risk Factors, Interaction
- Trial name
- SDLE (NCT05425303)
- Testing
- Exposure to risk for injury
- Where
- Greece
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Patras
Depression
Effectiveness of Parent-Child Interaction and Emotion Development Therapy in Treating Preschool Children With Depression
This study will evaluate the effectiveness of parent-child interaction therapy that includes an emotion development component in treating depression in preschool children.
- Trial name
- NCT00595283
- Testing
- Parent Child Interaction Therapy-Emotion Development (PCIT-ED), Developmental Education Parenting Intervention (DEPI)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Washington University School of Medicine
Epilepsy
A Study of Possible Drug-drug Interactions Between Stiripentol or Valproate and Cannabidiol in Patients With Epilepsy
This trial consists of 2 parts: a double-blinded phase and an open-label extension phase. The blinded phase only will be described in this record.
- Trial name
- NCT02607891
- Testing
- GWP42003-P
- Where
- 5 sites in Netherlands, Spain and 1 more
- Volunteers
- 35 people
- Sponsor
- Jazz Pharmaceuticals
Acute Coronary Syndrome
Potential Drug Interactions With Bisoprolol in Egyptian Patients With ACS
Acute coronary syndrome (ACS) is any group of clinical symptoms compatible with acute myocardial ischemia and includes unstable angina (UA), non-ST-segment elevation myocardial infarction (NSTEMI), and ST-segment elevation…
- Trial name
- NCT05536284
- Testing
- Bisoprolol Fumarate Tablets
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Damanhour University
Parent-Child Relations
ATTACH™ Program: Promoting Vulnerable Children's Health at Scale
ATTACH™ is a psycho-educational parenting program, designed with community agencies serving families of preschoolers affected by toxic stress (e.g.
- Trial name
- ATTACH™ (NCT04853888)
- Testing
- ATTACH™ Parenting Program
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Language Development
Do Video Materials Help Parents to Support Infant Development?
The aim of this project is to assess whether video materials from the BBC Tiny Happy People (THP) campaign are effective in terms of improving the language skills of socioeconomically disadvantaged children before they start…
- Trial name
- NCT04919343
- Testing
- BBC Education Tiny Happy People videos, Physical health control intervention
- Where
- United Kingdom
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Healthy
Sensitive Periods in Early Flavor Learning
Flavor is the primary dimension by which young children determine food acceptance. However, children are not merely miniature adults since sensory systems mature postnatally and their responses to certain tastes differ markedly…
- Trial name
- NCT00994747
- Testing
- Nutramigen (Flavor and Type of Infant Formula), Enfamil, milk-based formula
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center