Clinical trials: Medication-Related Osteonecrosis of Jaw
Osteonecrosis Due to Drugs, Jaw
Plasma Rich in Growth Factors for Treatment of Medication Related Osteonecrosis of the Jaw
Medication related Osteonecrosis of the Jaw (MRONJ) consists of progressive destruction of bone in the maxillofacial area. It is an established complication which occurs in patients who take two main classes of antiresorptive…
- Trial name
- NCT03390777
- Testing
- surgery, PRGF after surgery
- Volunteers
- 150 people
- Sponsor
- University of Roma La Sapienza
Osteomyelitis of Jaw
Management of Medication Related Osteonecrosis of the Jaws With Double Periosteal Flap Closure
20 patients with MRONJ underwent surgical debridement using piezosurgery then closure using double periosteal flap
- Trial name
- NCT07177378
- Testing
- management of medication related osteonecrosis of the jaw
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tanta University
Medication-Related Osteonecrosis of Jaw
Assessment of Er:YAG Laser-Assisted Surgical Treatment in Medication-Related Osteonecrosis of the Jaw (MRONJ): A Clinical Trial
The aim of this study is assessing the effectiveness of the Er:YAG laser in relation to the use of conventional surgery in the treatment of drug-induced osteonecrosis of the jaws (MRONJ).
- Trial name
- NCT07029815
- Testing
- irradiation with Er:YAG laser, Tissue preparation
- Where
- Poland
- Volunteers
- 65 people
- Sponsor
- Wroclaw Medical University
Medication Related Osteonecrosis of the Jaw
MRONJ and Polynucleotides-Hyaluronic Acid Hydrogel (Regenfast®)
Several circumstances or conditions, such as wound extension or disease, can affect the hard and soft tissue healing after surgical treatment of MRONJ. Supportive therapies are therefore needed to help tissues wound healing.
- Trial name
- REG-MRONJ-1 (NCT06984107)
- Testing
- MRONJ resection plus PN+HA
- Volunteers
- 10 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS