Clinical trials: Memory Problems
Mild Cognitive Impairment, Neurocardiogenic Syncope
VINCI-AD: An Investigation of Transcutaneous Vagus Nerve Stimulation in Mild Cognitive Impairment.
The VINCI-AD study will investigate the impact of non-invasive vagus nerve stimulation (VNS) on memory in participants with existing mild memory impairment. VNS is a safe, existing treatment, licensed in epilepsy and depression.
- Conditions
- Mild Cognitive Impairment, Neurocardiogenic Syncope, Memory Impairment, Inflammatory Response
- Trial name
- NCT05514756
- Testing
- Active t-VNS, Baseline assessments
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- Tallaght University Hospital
Dementia, Memory Impairment
Cultural and Linguistic Adaptation and Normative Study of the Turkish Version of the Free and Cued Selective Reminding Test: 16-Word Version (FCSRT-T)
An Adaptation Study of Free and Cued Selective Reminding Test in Turkish
- Trial name
- FCSRT-T (NCT05756231)
- Testing
- SIHT-16
- Where
- Turkey (Türkiye)
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Child Development, Child Behavioral Problems
LOVING (Learning About Our Behavior is Valuable for Increasing Nurturing Relationships and Healthy Growth) RCT
The LOVING study is a randomized controlled trial designed to determine whether adaptations to an internationally recognized parenting program that enhances sensitive caregiving likewise improves sensitive caregiving in Singapore…
- Conditions
- Child Development, Child Behavioral Problems, Parent Child Relationship
- Trial name
- LOVING (NCT07687524)
- Testing
- VIPP-SD-SingH, "Video-Feedback Intervention to Promote Positive Parenting and Sensitive Discipline Adapted for the Singapore Context with a Health Component", CARE-SD, "Caregiver Awareness of Relationships through E-learning for Sensitivity and Discipline", NeuroEducation for Parents
- Where
- 5 sites in Singapore
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Parkinson Disease, Mild Cognitive Impairment
Uncovering a Novel Therapeutic Target to Reduce Dementia Risk in Parkinson's Disease
The present study is a proof-of-concept clinical trial to test the efficacy of low doses of a repurposed anti-epileptic drug (levetiracetam) in treating memory problems in Parkinson's disease (PD).
- Conditions
- Parkinson Disease, Mild Cognitive Impairment, Memory Impairment
- Trial name
- TRIP (NCT04643327)
- Testing
- Levetiracetam
- Where
- Australia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Difficulty Focusing, Poor Concentration
A Clinical Trial to Evaluate the Effects of a Supplement on Children's Focus and Energy
This study will evaluate the effects of the Auri Super Mushroom Daily Gummies For Kids on focus and energy in children aged 4-12.
- Conditions
- Difficulty Focusing, Poor Concentration, Poor Memory, Low Energy
- Trial name
- NCT07766642
- Testing
- Auri Super Mushroom Daily Gummies For Kids
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Auri Nutrition
T1DM, Sleep Disorders, Circadian Rhythm
Influence of Circadian Clock on Hormonal, Metabolic, Neurocognitive Markers in Adolescents With and Without Diabetes
Type 1 diabetes mellitus (T1DM), makes its appearance during childhood and youth, but management implications last till late adulthood.
- Conditions
- T1DM, Sleep Disorders, Circadian Rhythm, ADHD, Memory Impairment
- Trial name
- NCT04054934
- Testing
- Reversed Circadian Rhythm, Normal Circadian Rhythm
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Cochlear Implants
Pitch Perception and Memory: Deficits and Training
Pitch perception and memory are central in auditory cognition, in particular for sound source segregation and recognition, speech prosody and music processing.
- Trial name
- Pitch_Train (NCT03707691)
- Testing
- Listening tests. Pitch training protocol, visuo-spatial training protocol, EEG/MEG/MRI recordings.
- Where
- France
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Intra Cerebral Hemorrhage, ICH - Intracerebral Hemorrhage
REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study
The investigators propose to perform serial detailed cognitive, motor, behavioral, and blood collection follow-up using longitudinal structured telephone interviews of an anticipated 350 ICH survivors enrolled in Minimally…
- Conditions
- Intra Cerebral Hemorrhage, ICH - Intracerebral Hemorrhage, ICH, Hemorrhage
- Trial name
- ICH03 (NCT05611918)
- Where
- 26 sites in United States
- Volunteers
- 350 people
- Sponsor
- Johns Hopkins University
Neurofibromatosis 1
Non-invasive Stimulation in Neurofibromatosis Type 1
Intellectual impairments are a significant cause of morbidity in children with birth defects along with long term implication on academic and occupational functioning.
- Trial name
- tDCS is NF1 (NCT03310996)
- Testing
- Transcranial direct current stimulation
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Manchester
Lack of Satiety, Dietary Modification
Breakfast Consumption in Preschoolers: Satiety, Diet Quality and Memory
One important factor determining school performance is the consumption of breakfast. While research has shown that older children perform better in school after consuming breakfast, there are little data for preschool-age…
- Conditions
- Lack of Satiety, Dietary Modification, Memory Deficits, Obesity
- Trial name
- NCT02122224
- Testing
- High fiber breakfast, High Protein Breakfast, High Protein/High Fiber Breakfast
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Purdue University
Memory Impairment, Executive Dysfunction
The Effects of Playing High School Football on Later Life Cognitive Functioning and Mental Health
The purpose of this study is to assess the effect of playing high school football on later in life cognitive functioning and mental health.
- Conditions
- Memory Impairment, Executive Dysfunction, Depression
- Trial name
- NCT02833129
- Volunteers
- 3,904 people
- Sponsor
- University of Pennsylvania
Cognitive Impairment, Cognitive Decline
Lithium Treatment to Prevent Cognitive Impairment After Brain Radiotherapy
Randomized, placebo-controlled, double-blinded, parallel group clinical trial to investigate if 6 months of oral lithium tablets (S-lithium 0,5-1,0 mmol/l) will prevent cognitive decline after brain radiotherapy in pediatric…
- Conditions
- Cognitive Impairment, Cognitive Decline, Radiotherapy Side Effect, Radiotherapy; Complications
- Trial name
- LiBRA (NCT06051240)
- Testing
- Lithium
- Where
- 2 sites in Sweden
- Volunteers
- 84 people
- Sponsor
- Region Stockholm
Psychotic Disorders, Cannabis Use Disorder
Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls With Cannabis Use
Cognitive impairment is well established in people with psychosis and is associated with cannabis use. The current study will investigate the neurobiological basis of cognitive change associated with 28-days of cannabis…
- Conditions
- Psychotic Disorders, Cannabis Use Disorder, Cannabis Dependence, Cannabis Use
- Trial name
- NCT05445180
- Testing
- Contingency management
- Where
- Canada
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Emotions, Memory Deficits
Brain Response to Treatment for Pediatric PTSD
This study will examine how brain activation changes as a result of behavioral treatment for posttraumatic stress disorder (PTSD) in adolescents.
- Conditions
- Emotions, Memory Deficits, Post-traumatic Syndrome
- Trial name
- NCT01806701
- Testing
- Trauma-focused cognitive behavioral therapy
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pediatric Iron Deficiency, Anemia
Choline and Iron Deficiency
BACKGROUND: Iron deficiency limits the neurodevelopmental potential of more than 200 million children each year. Iron therapy is typically started when iron deficiency anemia is first diagnosed after screening for anemia or…
- Trial name
- NCT06527391
- Testing
- choline bitartrate
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Minnesota
Psychoses, Substance-Induced
Prevention of N-methyl-D-aspartate (NMDA) Antagonist-induced Psychosis in Kids
Ketamine, an FDA approved anesthetic agent, is becoming the sedative/analgesic of choice for emergency sedation in children because it causes deep sedation with minimal respiratory depression in comparison to other available…
- Trial name
- NCT00205712
- Testing
- Ketamine, Dexmedetomidine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Epilepsy, Cognitive Dysfunction, Cognitive Disorder
HOBSCOTCH-YOUTH and Young Adults
The goal of this clinical trial is to learn more about the home-based epilepsy self-management program, HOBSCOTCH, for improving cognitive function (thinking and memory) and quality of life specifically in young adults, ages 18 …
- Conditions
- Epilepsy, Cognitive Dysfunction, Cognitive Disorder, Memory and Thinking Problems
- Trial name
- NCT07735715
- Testing
- HOBSCOTCH/HOBSCOTCH-YOUTH
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Memory Deficits
Memory Rehabilitation by Means of Working Memory Training in Combination With a Recollection Training
Memory deficits after brain damage are common and there is still a need for evaluated therapy methods. In this study we compare two therapeutic interventions and investigate whether therapy effects can be found on…
- Trial name
- NCT02790151
- Testing
- Standard Therapy, Experimental Intervention
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- University of Oldenburg
Dementia, Cognitive Decline
Ammonia Levels and Cognitive Impairment
The purpose and objective of this study is to determine the prevalence of elevated ammonia levels in subjects with cognitive impairment, and to observe if treating the cause of the elevated ammonia level improves mental status.
- Conditions
- Dementia, Cognitive Decline, Cognitive Impairment, Developmental Delay
- Trial name
- NCT02059356
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Duke University
Autism Spectrum Disorder
The Relationship Between Social Memory Disorders and Sleep Spindles in Children With Autism Spectrum Disorder
Research background and project basis Autism spectrum disorder (ASD) is a lifelong neurodevelopmental disorder characterized by social disorders and repetitive stereotypical behavior.
- Trial name
- NCT06306378
- Testing
- social memory levels and spindle levels
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University