Clinical trials: Menopausal
Recurrent Urinary Tract Infection
Antibiotic Bladder Instillations vs. Oral Suppression for the Treatment of Recurrent Urinary Tract Infections
This is a research study that aims to determine if antibiotic bladder instillations (placing an antibiotic directly into the bladder) over several sessions at the office is a good option to prevent recurrent urinary tract…
- Trial name
- NCT04285320
- Testing
- Intravesical antibiotic instillation, Antibiotic oral suppressive therapy
- Volunteers
- 100 people
- Sponsor
- Atlantic Health System
Menopause
The Effect of Soya Foods on Cognitive Function and Menopausal Symptoms in Postmenopausal Women.
Participants will be randomly assigned to one of three treatment groups to receive soyafoods (Alpro drinks) providing a low (<10 mg), medium (35mg) or high-dose (60 mg) of isoflavones daily for a period of 12 weeks.
- Trial name
- NCT03561662
- Testing
- Alpro soya drinks
- Where
- United Kingdom
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Genitourinary Syndrome of Menopause
The Outcome of Chinese Women With Genitourinary Syndrome of Menopause Treated With Vaginal Dehydroepiandrosterone
Genitourinary syndrome of menopause (GSM) is a common condition with prevalence was up to 80%. Symptoms associated with GSM include vaginal or vulvar dryness, itchiness, dyspareunia, increased urinary frequency or urgency and…
- Trial name
- NCT05434351
- Testing
- vaginal dehydroepiandrosterone
- Where
- Hong Kong
- Volunteers
- 4 people
- Sponsor
- Chinese University of Hong Kong
Hot Flashes, Heart Rate
Influence of Nebivolol on Postmenopausal Women
After menopause the coronary artery disease (CAD) risk increases rapidly to an equivalent risk of men with the same age. The rising incidence of CAD could be a subsequent decline of endogenous estrogen blood levels after the…
- Conditions
- Hot Flashes, Heart Rate, Blood Pressure, Endostatin
- Trial name
- NCT01161823
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Ovarian Aging, Adverse Pregnancy Outcomes
The Bone and hEArt Health Consequences of Ovarian agiNg (BEACON) Study
Ovarian aging is a major driver of a woman's long-term health and disease risk. In particular, the rapid decline in the ovarian reserve that occurs with the menopause transition is linked to a striking increase in the risk for…
- Trial name
- BEACON (NCT07621965)
- Volunteers
- 655 people
- Sponsor
- Indiana University
Event, Life Change
Pharmacy Education During Covid-19 Outbreak
Coronavirus disease 2019 (COVID-19) outbreak is considered one of the most important public health crisis all over the world. General recommendations and rules around the world have been legislated to avoid or delay transmission…
- Trial name
- NCT04409951
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Damanhour University
Turner Syndrome, Infertility, Female
Turner Syndrome Minipuberty Study
Rationale: Due to accelerated germ cell loss, infertility is a major problem in girls with Turner syndrome (TS). Therefore, cryopreservation of ovarian tissue or oocytes before exhaustion of the ovarian reserve may preserve…
- Conditions
- Turner Syndrome, Infertility, Female, Premature Ovarian Failure, Gonadal Dysgenesis
- Trial name
- Minipuberty (NCT04189406)
- Testing
- Venapunction
- Where
- 13 sites in Denmark, Germany and 3 more
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Urinary Tract Infections
Impact of Cranberry Juice Consumption on Gut and Vaginal Microbiota in Post-menopausal Women
This study was a randomized, placebo-controlled, crossover, pilot dietary intervention. Ocean Spray Cranberries, Inc provided the experimental and placebo beverages, which have been validated and used in previous studies [26-29].
- Trial name
- NCT04680325
- Testing
- Juice daily consumption
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Arkansas, Fayetteville
Breast Cancer
ITA - Clinical Study Comparing ARIMIDEX™ With NOLVADEX™ in Women With Breast Cancer Treated With NOLVADEX for at Least 2 Years
The purpose of this study was to assess the difference in disease-free survival between post-menopausal women with hormone receptor-positive early breast cancer who switched from tamoxifen to anastrozole and those who continued…
- Trial name
- NCT00286117
- Testing
- Anastrozole, Tamoxifen
- Where
- 25 sites in Italy
- Volunteers
- 448 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Type 2
A Research Study Looking Into the Effect of NNC0519-0130 on Blood Levels of a Birth Control Pill and Emptying of the Stomach in Women After Menopause
The purpose of the study is to investigate if NNC0519-0130 affects the blood levels of a birth control pill that contains the two hormones ethinylestradiol and levonorgestrel.
- Trial name
- NCT06513104
- Testing
- NNC0519-0130, Levonorgestrel + Ethinylestradiol, Paracetamol
- Where
- Germany
- Volunteers
- 47 people
- Sponsor
- Novo Nordisk A/S
Menopause, Urinary Infections
Preventive Effect of Treatment With Estradiol Vaginal Tablets on Recurrent Urinary Tract Infections in Post-menopausal Women
This trial is conducted in Europe. The aim of this trial is to investigate the preventive effect of treatment with estradiol vaginal tablets on recurrent urinary tract infections (RUTI) in post-menopausal women with signs of…
- Trial name
- NCT00560924
- Testing
- estradiol, 25 mcg
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Novo Nordisk A/S
Postmenopause
Effects of Wellnara on Climacteric Symptoms
Aim of this NIS is to obtain further information on efficacy, tolerability, and acceptance of Wellnara in a large user population under the conditions of routine medical practice.
- Trial name
- NCT00913926
- Testing
- E2/LNG oral (Wellnara, BAY86-5029)
- Where
- Germany
- Volunteers
- 749 people
- Sponsor
- Bayer
Cardiovascular Disease, Skin Health
Effects of Anthocyanin on Skin Health and Markers of Cardiovascular Disease Risk
The purpose of this study is to determine whether short-term exposure to a compound found in some fruits and vegetables (anthocyanin), is effective in improving skin health and reducing the levels of various markers of…
- Conditions
- Cardiovascular Disease, Skin Health, Postmenopause
- Trial name
- NCT00574574
- Testing
- anthocyanin
- Where
- United Kingdom
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Breast Cancer
Anti-tumour Effects & Tolerability of Faslodex Alone or in Combination With Arimidex in Post Menopausal Women Prior to Surgery for Primary Breast Cancer
To compare the anti-tumour effects as measured by changes in various biomarkers, of a combination of Faslodex and Arimidex with Faslodex alone and Arimidex alone in postmenopausal women patients with primary breast cancer who are…
- Trial name
- NCT00259090
- Testing
- Fulvestrant, Anastrazole
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- AstraZeneca
Anxiety Disorder/Anxiety State, Depressive Disorder/Psychology
Trial of the Youth Readiness Intervention
The research will first examine data obtained from YRI participants to investigate effects of the group sessions on psychosocial and functioning outcomes in youth.
- Conditions
- Anxiety Disorder/Anxiety State, Depressive Disorder/Psychology, Social Problems/Psychology, Stress, Psychological
- Trial name
- YRI (NCT01684488)
- Testing
- YRI, EducAid educational programming
- Where
- Sierra Leone
- Volunteers
- 443 people
- Sponsor
- Boston College
Hot Flashes, Menopause
Use of Black Cohosh and Red Clover for the Relief of Menopausal Symptoms
This Phase II study, a follow-up to a Phase I trial in normal volunteers, will determine the efficacy of black cohosh and red clover for the relief of menopausal symptoms.
- Trial name
- NCT00066144
- Testing
- Cimicifuga racemosa, Trifolium pratense, Black cohosh
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Genitourinary Syndrome of Menopause
MonaLisa Touch Randomized Double-Blind Placebo Controlled Study
Aim of the study: To assess the efficacy of MonaLisa Touch procedure for the management of genitourinary syndrome of menopause (GSM) in a randomized double-blind placebo controlled study.
- Trial name
- NCT03331328
- Testing
- MonaLisa Touch
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Michigan Institution of Women's Health PC
Breast Cancer
Survey in Post-menopausal Women Followed up After Treatment With Anastrozole as Adjuvant Therapy
The purpose of this survey is to describe long-term tolerance as seen under current conditions of use for anastrozole.
- Trial name
- ARIES (NCT00542594)
- Volunteers
- 1,840 people
- Sponsor
- AstraZeneca
Effects of Chemotherapy
The Longitudinal Ovarian Reserve Study
Postmenarchal female cancer patients scheduled to undergo cancer therapy may enroll in this study to assess changes in existing and novel surrogate measures of fertility potential before, during and after chemotherapy.
- Trial name
- NCT02395341
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Postmenopausal Osteoporosis
PRIOR Study - A Study of Ibandronate (Boniva) in Postmenopausal Women With Osteoporosis or Osteopenia
The purpose of this study is to evaluate treatment adherence to different regimens of ibandronate in postmenopausal women with osteoporosis or osteopenia who are intolerant to daily or weekly alendronate or risedronate therapy…
- Trial name
- NCT02598453
- Testing
- Ibandronate
- Where
- 60 sites in United States
- Volunteers
- 545 people
- Sponsor
- Hoffmann-La Roche